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  • serotype
  • The results showed that a new serotype, combined with resistance to beta-lactams, could emerge in a susceptible strain via a single transformation event. (harvard.edu)
  • Ceftriaxone
  • Ceftriaxone resistance was not observed. (hindawi.com)
  • Using Clinical and Laboratory Standards Institute (CLSI) breakpoints, the correlation between the zones of inhibition of the ODD test and the MICs of penicillin and ceftriaxone was determined. (vanopijnenlab.com)
  • Conclusions There was good correlation between ODD zones of inhibition and penicillin meningeal breakpoints but weak correlation between the ODD results and non-meningeal breakpoints for both penicillin and ceftriaxone. (vanopijnenlab.com)
  • MICs
  • Comparison of the ODD test zones of inhibition and the penicillin MICs, using the CLSI meningeal breakpoints, showed good correlation (Cohen's kappa coefficient = 0.8239). (vanopijnenlab.com)
  • penA
  • However, when a coresident penA mutation is present, resistance increases 8- to 10-fold ( 10 , 22 , 24 ). (asm.org)
  • protein
  • Carapito R, Chesnel L, Vernet T et al (2006) Pneumococcal β-lactam resistance due to a conformational change in penicillin-binding protein 2x. (springer.com)
  • Marrec-Fairley M, Piette A, Gallet X et al (2000) Differential functionalities of amphiphilic peptide segments of the cell-septation penicillin-binding protein 3 of Escherichia coli . (springer.com)
  • Witherden, EA 2014 , 'Phenotypic and genotypic characterisation of altered penicillin-binding protein 3 (PBP3) mediated resistance in Haemophilus influenzae and Haemophilus haemolyticus', PhD thesis, University of Tasmania. (edu.au)
  • Transformation
  • When introduced into strain FA19 by transformation, a single base pair deletion in the mtrR promoter sequence from strain FA6140 was sufficient to provide high-level resistance to HAs (e.g., erythromycin and Triton X-100) but only a twofold increase in resistance to penicillin. (asm.org)