• Nine years prior to admission, he underwent nonanatomic left lateral liver resection for a 2 cm well-differentiated hepatocellular carcinoma using a "sandwich technique. (hindawi.com)
  • The Dutch D1/D2 trial reported an increased median survival for a subgroup of patients with single metastasis who underwent resection. (unige.ch)
  • After two or three cycles of DOS, patients underwent surgical resection. (bvsalud.org)
  • Patients and Methods: Between 2007 and 2015, 62 consecutive patients underwent surgical resection for gastric submucosal tumors. (iiarjournals.org)
  • Case Report: In June 2022, two patients with Siewert type II carcinoma of esophagogastric junction underwent laparoscopic proximal gastrectomies, using a novel esophagogastrostomy technique of Conical remnant GastroEsophageal side-Overlap fundoplication (CGEO). (cancerdiagnosisprognosis.org)
  • Outcomes were poor overall for patients with BM, but patients who underwent neurosurgical resection had improved survival. (elsevierpure.com)
  • Stage I-III (locoregional disease) - Available modalities are endoscopic therapies (eg, mucosal resection or ablation), esophagectomy, preoperative chemoradiation, and definitive chemoradiation. (medscape.com)
  • In addition, the guidelines recommend endoscopic eradication therapy with RFA, photodynamic therapy (PDT), or endoscopic mucosal resection (EMR) rather than surveillance for patients with high-grade dysplasia. (medscape.com)
  • It is a thin, weblike constriction located at the squamo-columnar mucosal junction at or near the border of the LES. (medquizzes.net)
  • Torek F. The first successful resection of the thoracic portion of the esophagus for carcinoma. (medscape.com)
  • Carcinoma of the esophagus: successful resection of lower end of esophagus with reestablishment of esophageal gastric continuity. (medscape.com)
  • The Society of Thoracic Surgeons practice guidelines on the role of multimodality treatment for cancer of the esophagus and gastroesophageal junction. (medscape.com)
  • The CGEO procedure has advantages for gastric tube reconstruction and side-to-side overlap anastomosis of the esophagus to gastric remnant and is suitable for radical resection of type II esophagogastric junction carcinoma or proximal gastric cancer. (cancerdiagnosisprognosis.org)
  • A single-institution retrospective review identified 583 patients treated from January 1997 to January 2016 for stages I through IV cancer of the esophagus and esophagogastric junction (follow-up, ≥3 months). (elsevierpure.com)
  • The National Comprehensive Cancer Network (NCCN) guidelines and Memorial Sloan Kettering's internal guidelines both split the esophagus and the stomach at the gastroesophageal junction. (cancernetwork.com)
  • The third and most prominent angulation occurs after traversing the diaphragmatic crura and above the esophagogastric junction, where the terminal esophagus turns to the left (see Figure 1). (sts.org)
  • In Hong Kong and Malaysia, many EGJ adenocarcinomas have been detected at a stage not amenable to endoscopic resection. (elsevierpure.com)
  • In Japan, histological curability criteria for endoscopic resection cases have not been established. (elsevierpure.com)
  • Patients with oligometastatic gastric and esophagogastric junction cancer are randomized after chemotherapy to either undergo resection followed by adjuvant chemotherapy or to undergo definitive chemotherapy. (unige.ch)
  • This report presents an unusual case of synthetic mesh used in a liver resection and its eventual migration and intraluminal erosion into the stomach. (hindawi.com)
  • a) Left, computed tomography scan 7 years after resection, showing the mesh (arrow) extraluminal to the stomach and duodenum. (hindawi.com)
  • The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction - a phase III trial of the German AIO/CAO-V/CAOGI. (helsedirektoratet.no)
  • Biweekly fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) for patients with metastatic adenocarcinoma of the stomach or esophagogastric junction: a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie. (helsedirektoratet.no)
  • In particular, LECS may have merit in the removal of upper-third tumors by avoiding wedge resection, which carries the risk of excessive resection and deformity of the stomach. (iiarjournals.org)
  • Until recently, wedge resection (WR) ( 5 , 6 ) or alternative gastrectomy have been mainly performed, despite accurate pre- and intraoperative information on tumor location in the stomach and tumor type (intra- or extragastric growth type). (iiarjournals.org)
  • lt;p>The aim of the study was to assess the quality of life (QoL) in patients exposed to proximal resection of the stomach in various modifications. (vestnik-surgery.com)
  • Although proximal gastrectomy allows for retention of distal stomach function, the anatomy of the esophagogastric junction is destroyed, and the capacity to prevent reflux is lost. (cancerdiagnosisprognosis.org)
  • 1. Introduction Cancers of the stomach (GC), the gastroesophageal junction (GEJ) and the distal oesophagus are the second ⇑ Corresponding author at: Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany. (docksci.com)
  • Preoperative diagnosis of the cyst hystotype is rarely established via endoscopic ultrasound (EUS)-guided fine-needle aspiration, and resection is usually performed due to uncertainty about the origin of the lesion (the pancreas or stomach). (e-ce.org)
  • 6. Specimen extraction : The resection stomach is extracted via the umbilical port under vision with the camera being introduced via the 13 mm right sided port. (lapguru.com)
  • Guideline] NCCN Clinical Practice Guidelines in Oncology: Esophageal and Esophagogastric Junction Cancers. (medscape.com)
  • Abstract Gastroesophageal cancers comprising gastric cancer (GC), and cancers of the distal oesophagus and gastroesophageal junction (GEJ) are a global health threat. (docksci.com)
  • Can multimodal treatment with tumor resection and metastasectomy combined with perioperative chemotherapy, increase the chances of survival in oligometastatic patients? (unige.ch)
  • Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. (helsedirektoratet.no)
  • Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer: The AIO-FLOT3 Trial. (helsedirektoratet.no)
  • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. (helsedirektoratet.no)
  • Generally, clinically staged T1N + M0 and T2-T4aN(any)M0 gastric cancer requires surgical resection with adequate lymphadenectomy, together with perioperative or adjuvant chemotherapy. (frontiersin.org)
  • We conducted the first phase 2 trial to investigate the efficacy and safety of neoadjuvant docetaxel , oxaliplatin , and S-1 (DOS) chemotherapy for cStage III gastric or esophagogastric junction (EGJ) adenocarcinoma in Japan . (bvsalud.org)
  • In February 2022, the dosing of the first patient was completed in the Phase III clinical trial of TUOYI ® in combination with standard chemotherapy as the adjuvant treatment after radical resection of gastric or esophagogastric junction adenocarcinoma (JUPITER-15 study, NCT05180734). (cambodiatribune.com)
  • Recently the therapeutic treatment for advanced, stage T2-T4 gastro-oesophageal junction cancer and those adjacent to the regional lymph nodes involves neoadjuvant chemotherapy with subsequent surgical intervention. (akjournals.com)
  • A potential alternative for adenocarcinoma tumors at the gastroesophageal junction is perioperative chemotherapy. (cancernetwork.com)
  • Especially in highly malignant gastric submucosal tumors, such as gastrointestinal stromal tumors (GIST), partial resection using laparoscopic surgery and open surgery have common indications according to the Japanese ( 3 , 4 ) and National Comprehensive Cancer Network (NCCN) guidelines. (iiarjournals.org)
  • WR may require a relatively large resection of the gastric wall causing subsequent deformity and be a potential risk for reduced oral intake, whereas alternative gastrectomy for tumors near the esophago-gastric junction or pylorus, performed to avoid the definite risk of subsequent deformity due to WR ( 7 - 9 ), has a high probability of causing post-gastrectomy syndromes and nutritional disorders ( 10 - 13 ). (iiarjournals.org)
  • Gastrointestinal stromal tumors (GIST) of the esophagogastric junction might pose a major problem to surgical resection. (biomedcentral.com)
  • Postoperative chemoradiation is the preferred option after complete gastric resection for patients with T3-T4 tumors and node-positive T1-T2 tumors. (jnccn.org)
  • Conventionally, proximal tumors (Esophagogastric Junction (EGJ)) are distinguished from distal tumors. (gavinpublishers.com)
  • For tumors of the gastroesophageal junction, the letter U was associated with the word cardia (II or III). (gavinpublishers.com)
  • Eleftheriadis N, Inoue H, Ikeda H, Onimaru M, Maselli R, Santi G. Submucosal tunnel endoscopy: Peroral endoscopic myotomy and peroral endoscopic tumor resection. (wjgnet.com)
  • It has been more than 140 years since Theodor Billroth's (1829-1894) first successful gastric resection for cancer in 1881. (frontiersin.org)
  • Regardless of the scientific and technological advancement, the development of a multimodal treatment approach using resection (surgical or endoscopic) is still the foundation of curative management in gastric cancer ( 7 ). (frontiersin.org)
  • Primary DCF therapy for patients with unresectable esophageal cancer resulted in conversion surgery for 41.7% (20/48) of patients, in which R0 resection was achieved in 19 patients (39.6%) [ 5 ]. (biomedcentral.com)
  • it is a sign that the cancer has progressed beyond the point at which surgical resection remains possible. (medscape.com)
  • In instances of upper gastric cancer or partial esophagogastric junction cancer, total gastrectomy is the standard surgical intervention ( Zhonghua Wei Chang Wai Ke Za Zhi 24(5) (2021)">3 ). (cancerdiagnosisprognosis.org)
  • Neoadjuvant oncological treatment for gastro-oesophageal junction cancer previously consisted of the intravenous administration of epirubicin, cisplatin and fluorouracil (ECF) or epirubicin, cisplatin and capecitabine (ECX) combination (Group I). In the course of the new protocol (FLOT-, F: 5-FU, L: leucovorin, O: oxaliplatin, T: docetaxel), patients were included with resectable gastro-oesophageal junction cancer who had a clinical-stage cT2 or higher nodal positive cN+ disease (Group II). (akjournals.com)
  • However, the traditional open radical resection of esophageal cancer usually causes big traumas and high risk, and its efficacy is not satisfactory [ 2 , 3 ]. (biomedres.info)
  • This international, multicenter, randomized, double-blind phase III study intends to recruit 680 patients who have received radical gastrectomy (R0 resection, D2 or more extended lymphadenectomy) with postoperative pathological stage II or III (AJCC Cancer Staging Manual, 8th Edition) gastric or EGJ adenocarcinoma to evaluate the efficacy and safety of JS001 combined with postoperative adjuvant chemotherapy versus placebo combined with postoperative adjuvant chemotherapy. (centerwatch.com)
  • We investigated whether the incidence of brain metastasis (BM) from primary esophageal and esophagogastric cancer is increasing. (elsevierpure.com)
  • and a type III tumor is a proximal gastric cancer extending upwards to the gastroesophageal junction. (cancernetwork.com)
  • I beskrivningen av förloppet står det att bland annat symtom som nytillkomna sväljsvårigheter ska väcka misstanke om cancer och då ska en snabb remiss skickas för gastroskopi (undersökning där en slang med kamera förs ner i magsäcken). (cancercentrum.se)
  • SVF startas då en välgrundad misstanke (VGM) uppstår, vilket innebär att det föreligger en betydande risk för cancer. (cancercentrum.se)
  • This case describes a patient who had undergone a left hepatic resection with mesh pledgets sutured along the cut edge of the liver. (hindawi.com)
  • Benefits and limits of hepatic resection for gastric metastases. (helsedirektoratet.no)
  • There is inadequate information to document the effectiveness of PEI as an alternative to surgical resection for the treatment of hepatic metastases. (aetna.com)
  • Multimodal treatment with resection doubled the median survival of oligometastatic patients in the German AIO-FLOT 3 study and as a consequence, the AIO-FLOT 5 (RENAISSANCE) trial was designed. (unige.ch)
  • The results of the ongoing randomized trials will show if oligometastatic patients benefit from a multimodal treatment with resection. (unige.ch)
  • The topics to be addressed in this session will include the methods of evaluation and imaging, the proper use of neoadjuvant therapy, and controversies in the extent of resection and lymphadenectomy. (facs.org)
  • Carcinoma of the cardia: carcinoma of the gastroesophageal junction-classification, pathology and extent of resection. (wikipedia.org)
  • We compared the results of the randomly assigned nine patients from earlier ECF/ECX protocol (Group I). We analyzed the effect of the different neoadjuvant therapy on tumor regression, and evaluated the types of possible side effects, type of surgery, and the oncological radicality of surgical procedures (number of removed regional lymph nodes, resection margins). (akjournals.com)
  • Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial. (helsedirektoratet.no)
  • The latter procedure, along with peritoneal lavage is recommended for stage IB-III patients before surgical resection ( 9 ). (frontiersin.org)
  • R0 resection was achieved in 44 (92%) patients , and the pathological response rate (≥ grade 1b) was 63% (30/48). (bvsalud.org)
  • Aim: In this study, we aimed to present our 10-year experience regarding clinicopathology characteristics and overall survival of 69 patients with adenocarcinomas of esophag ogastric junction (AEJs). (selcukmedj.org)
  • The patients were exposed to proximal gastric resection using isoperistaltic jejunogastroplasty (Merendino-Dillard-modified) (50 patients, main group I) and conventional proximal gastric resection using direct esophagogastroanastomosis (47 patients, control group II). (vestnik-surgery.com)
  • Proximal gastric resection with the Merendino-Dilard-modified digestive tract reconstruction creates more optimal conditions for the rapid rehabilitation of functional parameters, which positively affects the quality of life of patients. (vestnik-surgery.com)
  • Background: There is currently no universally-accepted, ideal method of esophagogastric reconstruction to address reflux esophagitis and anastomotic complications of esophagogastrostomy after proximal gastrectomy. (cancerdiagnosisprognosis.org)
  • The Siewert-Stein classification (often called the Siewert classification in less precise shorthand reference) is a system of anatomical classification used for adenocarcinomas of the esophagogastric junction. (wikipedia.org)
  • On computed tomography (CT), a hypodense, 6 ×4-cm-sized, oval-shaped lesion of uncertain origin was found along the gastric lesser curvature near the esophagogastric junction, extending toward the diaphragmatic pillar, adjacent to the pancreatic body, and close to the left adrenal gland ( Fig. 1A ). (e-ce.org)
  • Baxter Biosciences- Tisseel, Fibrin Sealant, for High Risk Bowel Anastomosis: Laparoscopic Gastric Bypass Roux en Y in the Porcine Model. (crownvalleycosmeticsurgery.com)
  • As a result, the esophagogastric junction takes position lateral to the xiphoid process of the sternum and to the left of the 12th vertebral body. (sts.org)
  • The first one changes from the median position at the pharyngoesophageal junction (Figures 2 and 3) toward the left at the base of the neck (see Figure 3). (sts.org)