Researchers cells use genetic. Medical search. Frequent questions

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. (news-medical.net)
By combining whole exome sequencing, machine learning, and network analysis, researchers have identified new, ultra-rare gene mutations within specific biological pathways that may contribute to eating disorders. (news-medical.net)
A study of nearly 6,000 families, combining three genetic sequencing technologies, finds that mutations that occur after conception play an important role in autism. (news-medical.net)
All identified mutations in the ESCO2 gene prevent the cell from producing any functional ESCO2 protein, which causes some of the glue between sister chromatids to be missing around the chromosome's constriction point ( centromere ). (medlineplus.gov)
which means both copies of the gene in each cell have mutations. (medlineplus.gov)
Deeper understanding of the pathobiology of non-small cell lung cancer (NSCLC) has led to the development of small molecules that target genetic mutations known to play critical roles in the progression to metastatic disease. (medscape.com)
[ 7 ] researchers identified EGFR mutations in 50.5% of surgically resected lung adenocarcinomas. (medscape.com)
These changes, called "mutations," cause your lung cells to grow out of control. (webmd.com)
Researchers are working all the time to look for new kinds of gene mutations. (webmd.com)
It has been discovered they can undergo genetic silencing to guard themselves from mutations. (icr.org)
Strong inflammation produced swelling, scarring, and genetic mutations to cells in the lungs of the mice. (cdc.gov)
Studying tumor cells for genetic mutations has led to many advances in the understanding of cancer. (scienceblog.com)
Instead, these cells influence surrounding cells to grow quickly, setting the stage for additional genetic mutations in cells that then become cancerous. (scienceblog.com)

A personal cancer treatment vaccine that targets distinctive "neoantigens" on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard. (news-medical.net)
The type and subtype of osteosarcoma is determined by looking at the tumor cells through a microscope. (cancer.net)
But when Murchison sequenced the tumor cells, their genetic makeup didn't match the DNA of their hosts. (popsci.com)
When the research team looked at PPB tumors to see if there is any DICER1 protein being made from the remaining normal copy of the gene, they were surprised by the results: "We expected to see that the tumor cells had no DICER1 protein giving us a nice explanation for why the tumor cells had gone haywire. (scienceblog.com)
ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)

While studying mice that had the KCNE2 gene removed from their genome, the researchers observed that the animals developed symptoms of hypothyroidism, especially during pregnancy, and gave birth to pups with dwarfism, alopecia (baldness) and cardiomegaly (enlarged heart). (sciencedaily.com)
Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. (nih.gov)
Genetic factors are thought to play a role in susceptibility to Behcet's disease, with the human leukocyte antigen (HLA) B-51 gene region of the genome, accounting for about 20 percent of genetic risk for the disease. (nih.gov)
The current study represents an important advance because it dramatically broadens the spectrum of genetic loci associated with Behcet's disease," said Dan Kastner, M.D., Ph.D., scientific director of the Intramural Research Program at the National Human Genome Research Institute and senior author of the study. (nih.gov)
Researchers conducted a genome-wide association study (GWAS) that enrolled 1,209 Turkish people affected by Behcet's disease and 1,278 unaffected Turkish people - all residents of the country. (nih.gov)
We manipulated the genome of zebrafish embryos and made bone-forming cells fluorescently visible in green. (scitechdaily.com)
Ongoing clinical trials use CRISPR for somatic cell genome editing to treat hereditary diseases or cancer. (cdc.gov)
In these studies, cells are either removed and edited in tissue culture and then readministered to the patient (ex vivo), or genome editors are packaged within viral vectors or lipid nanoparticles and given intravenously to home to specific tissues (in vivo). (cdc.gov)
The study provides new mechanistic evidence for a link between the cellular levels of Smarca5 and selected hallmarks of cancer that include genome instability, epigenetic reprogramming, evasion of cellular senescence, and cell immortality. (who.int)

NEW YORK (GenomeWeb) - 23andMe has launched its Genotyping Services for Research (GSR) platform which it hopes will help streamline scientists' ability to integrate genetic data into their studies and give study participants something back for their contribution. (genomeweb.com)
A team led by Johns Hopkins scientists has unraveled the first step in translating genetic information in order to build a protein, only to find that it's not one step but two. (news-medical.net)
Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus. (news-medical.net)
Led by scientists at UNC-Chapel Hill and UC-San Francisco, research reveals new non-coding genetic variants associated with Alzheimer's disease functioning in microglia - brain cells already implicated in the progression of this often-fatal. (newswise.com)
Scientists figuring out which of the 5,000-plus genetic variants associated with schizophrenia have an actual causal effect in the development of the condition. (newswise.com)
A research team including Dr. Stefan Schiller, his assistants Dr. Matthias Huber and Dr. Andreas Schreiber, and further groups from Freiburg and Hungary has refuted a long-held assumption in biology: The scientists have shown that it is not only possible to extend the functions of organelles â€" organs of the cell â€" but also to form them from scratch with the help of genetic blueprints. (healthmedicinet.com)
With the help of chemical reactions that were previously impossible in the cell, scientists now have new means at their disposal for producing biotechnological products. (healthmedicinet.com)
Historically, scientists haven't targeted the proteins in cancer cells that are involved in gene splicing," said Zefeng Wang, PhD, associate professor in the department of pharmacology and senior author of the Cancer Cell paper. (sciencedaily.com)
But scientists have not managed to isolate such cells from farm animals, and must rely instead on injecting genes randomly into early embryos. (newscientist.com)
In an attempt to address these issues with a genetic intervention, scientists reprogrammed neurons in mouse eyes to regrow after inducing glaucoma or crushing the optic nerve, and restored visual acuity in healthy, middle-aged mice to that of younger mice by expressing a set of genes known to revert cells to a pluripotent state, according to a study published in Nature Wednesday (December 2). (the-scientist.com)
In a 2016 Cell paper, a different group of scientists had activated these transcription factors in mice with progeria, a condition that causes premature aging, and found that the treatment alleviated symptoms and extended their lifespan by a matter of weeks. (the-scientist.com)
Many of the steps researchers once had to do manually to determine the structures of cells are becoming automated, allowing scientists to identify new structures at vastly higher speeds. (bigthink.com)
Scientists at the Walter and Eliza Hall Institute have for the first time visualised the molecular changes in a critical cell death protein that force cells to die. (edu.au)
Their success shows that cephalopods - which include squid and octopuses - can finally be studied using the same kind of genetic tools that have let scientists explore the biology of more familiar lab animals like mice and fruit flies. (npr.org)
What's more, scientists have sequenced the DNA that makes up this squid's genetic code. (npr.org)
The new model will permit more robust exploration of the cells, their properties and how scientists might circumvent the barrier for therapeutic purposes. (wisc.edu)
We can really investigate disease," says Palecek, noting that an ability to track cells as they progress through various phases of development can help scientists see the cascade of cellular events that occur as neurological conditions manifest themselves. (wisc.edu)
Our expansive research facilities, state-of-the-art technologies and unique location within The Royal Children's Hospital, are some of the reasons we're home to over 1,400 leading researchers and scientists. (edu.au)
Like sorting through multiple candid photos before posting the "good" ones on social media, researchers analyze hundreds of thousands of cryo-EM images for quality, reconstructing 3-D images of molecules that allow scientists to study how they behave. (cancer.gov)
Bringing together Universities and high school students, UniStem Day is an opportunity to foster learning, discovery and debate in the field of stem cell research - inspiring the scientists of tomorrow. (lu.se)
These and many more questions will be answered by PhD students, postdoctoral fellows, and senior scientists from Lund Stem Cell Center during UniStem Day 2024. (lu.se)

Tongcheng Qian , a Wisconsin postdoctoral researcher in chemical and biological engineering, led the study. (wisc.edu)

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. (genomeweb.com)
A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature. (news-medical.net)
Some of genetic variants regulate or alter the expression of genes involved in the. (newswise.com)
Genes previously known to be essential to the coordinated, rhythmic electrical activity of cardiac muscle -- a healthy heartbeat -- have now also been found to play a key role in thyroid hormone (TH) biosynthesis, according to researchers. (sciencedaily.com)
More importantly, biotechnologists will for the first time be able to manipulate the genes of cells from farm animals directly before growing them into embryos. (newscientist.com)
Researchers can insert new genes into these or knock out existing genes with great precision. (newscientist.com)
ABOVE: A mouse's crushed optic nerve, composed of retinal ganglion cell axons (bright streaks), regenerates after researchers injected a virus into the eye that contains genes whose activity dedifferentiates cells into a more youthful state, allowing them to regrow. (the-scientist.com)
They looked to genes that encode transcription factors that de-differentiate cells. (the-scientist.com)
Researchers identified two important transcription factors, genetic material responsible for regulating the expression of other genes. (theaggie.org)
If you have non-small-cell lung cancer (NSCLC), your disease began with changes to your genes. (webmd.com)
Genes are pieces of DNA inside each of your cells. (webmd.com)
Turn on" the genes that help your cells grow, divide, or stay alive. (webmd.com)
Turn off" the genes that make sure cells divide or die at the right time. (webmd.com)
The result of all these changes to your genes: Some cells become cancerous and grow out of control. (webmd.com)
Phoenix, AZ, October 10, 2006--Researchers at the Translational Genomics Research Institute (TGen) have released findings that further define the underlying genes associated with Alzheimer's Disease and neurofibrillary tangles (NFTs), a physical problem found in some brain cells of patients with Alzheimer's Disease. (tgen.org)
Published in the October issue of the journal, Neurobiology of Aging, TGen's researchers have identified several possible genes that could be linked to NFT formation. (tgen.org)
To identify the underlying causes of brain cell death, TGen researchers analyzed the extent to which genes are turned on or off in these cells that are so strongly affected by Alzheimer's Disease. (tgen.org)
Once we can figure out the genetic cause, we can then use these genes as potential therapeutic targets, meaning that we may be able to develop drugs to either turn on or turn off the genes responsible for causing Alzheimer"s Disease, ultimately affecting patient outcome in a meaningful way. (tgen.org)
The cells of the body contain our genetic make-up (DNA), which contains genes. (lu.se)
Most of us have learnt in school that our DNA is the same in all our cells that we cannot influence our genes. (lu.se)
the cells of the body can activate and deactivate genes, which means that the function of the cells can be altered. (lu.se)

The protein information, although modest, gave really important information on cell structure," said Mark Adams, a professor at the Jackson Laboratory, commenting on a presentation by Weill Cornell Medicine's Chris Mason on the use of NanoString's platforms to create human tissues atlases. (genomeweb.com)
Ramachandran credited single-cell RNA-seq for paving the way to a protein-friendly AGBT. (genomeweb.com)
At the conference, 10x presented a poster demonstrating a marriage of its sample multiplexing capabilities with cell surface protein detection in single cells. (genomeweb.com)
10x also said that it will offer a multiomics kit for its Visium spatial platform that can detect protein and gene expression on the same formalin-fixed, paraffin-embedded tissue section, as well as a 35-plex human immune cell profiling panel for the Visium CytAssist instrument. (genomeweb.com)
In a study of UK Biobank samples, the firm discovered more than 10,000 protein quantitative trait loci - associations between genetic variants and plasma protein levels - 85 percent of which were novel, she said. (genomeweb.com)
By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs. (news-medical.net)
â€œFor the first time ever, we have succeeded in forming a new organelle in the cell and equipping it with functions on the basis of rationally designed protein building blocks. (healthmedicinet.com)
This gene provides instructions for making a protein that is important for proper chromosome separation during cell division . (medlineplus.gov)
The gene product, Wiskott-Aldrich Syndrome Protein (WASp) is a 502 amino acid protein expressed within the cytoplasm of non-erythroid hematopoietic cells. (medscape.com)
WAS results from an X-linked genetic defect in the Wiskott-Aldrich syndrome protein (WASp). (medscape.com)
The protein RBM4, a molecule crucial to the process of gene splicing, is drastically decreased in multiple forms of human cancer, including lung and breast cancers, researchers have discovered. (sciencedaily.com)
People with SCD have abnormally shaped hemoglobin, the protein in red blood cells that carries oxygen from the lungs to bodily tissues. (medicalnewstoday.com)
This protein helps your cells grow and divide. (webmd.com)
The KRAS gene plays a role in making a protein called K-Ras, which helps cells grow and divide. (webmd.com)
As the former editor-in-chief of Science magazine and as a researcher who has studied hard-to-visualize large protein structures for decades, I have witnessed astounding progress in the development of tools that can determine biological structures in detail. (bigthink.com)
In the 20th century, electron microscopy offered even greater detail, revealing the elaborate structures within cells , including organelles like the endoplasmic reticulum, a complex network of membranes that play key roles in protein synthesis and transport. (bigthink.com)
Dr Peter Czabotar (left) and Dr Dana Westphal have visualised the molecular changes in a critical cell death protein that force cells to die. (edu.au)
NFTs are twisted remnants of a protein that is essential for maintaining proper cell structure and function found inside brain cells. (tgen.org)
An abnormality in this protein disrupts normal cell activity and is thought to contribute to cell death. (tgen.org)
They found that the benign cells that grew on the surface of the tumor had lost the DICER1 protein. (scienceblog.com)
These cells produce an abnormal protein called M protein , which can be detected in the blood and urine. (healthline.com)
SMN was an essential protein in all cell type and was reported to play important roles in multiple fundamental cellular homeostatic pathways. (bvsalud.org)
However, insertion of the Cre-recombinase cassette in the gene of interest can alter transcription, protein expression, or function, either directly, by modifying the landscape of the locus, or indirectly, due to the lack of genetic compensation or by indirect impairment of the non-targeted allele. (bvsalud.org)

A phase 2 study, led by Thomas W. Ferkol, MD, at the UNC School of Medicine, demonstrates safety and efficacy of idrevloride with hypertonic saline for treatment of primary ciliary dyskinesia, a rare genetic disorder that can lead to permanent lung. (newswise.com)
Roberts syndrome is a genetic disorder characterized by limb and facial abnormalities. (medlineplus.gov)
Sickle cell anemia, or sickle cell disease (SCD), is the most common form of inherited blood disorder. (medicalnewstoday.com)
Alzheimer's Disease is an irreversible, progressive disorder in which brain cells (called neurons) deteriorate, resulting in the loss of cognitive functions including memory, judgment and reasoning, movement coordination, and pattern recognition. (tgen.org)
It is a genetic disorder that results from a mutation in the hemoglobin gene, causing red blood cells to become sickle-shaped. (proprofs.com)
Researchers working on the Study to Explore Early Development (SEED) have recently published many studies reporting on important findings related to autism spectrum disorder (ASD). (cdc.gov)

Pixelgen Technologies, a Swedish startup , for example, stepped out in public to share its NGS-based technology for spatial resolution of cell surface proteins. (genomeweb.com)
Serge Saxonov, CEO and cofounder of 10x Genomics, agreed that his company's single-cell assays, which can pair antibody panels with transcriptomics, made proteins analysis more palatable to the AGBT crowd. (genomeweb.com)
Not only can the technology count proteins, but it also can provide information on their spatial arrangement on the cell. (genomeweb.com)
It can tell, for example, if the proteins are dispersed, clustered, or even concentrated at one "pole," such as in some cell binding events. (genomeweb.com)
The firm's kits offer the ability to analyze 75 proteins in up to 1,000 cells, with eight reactions in a kit. (genomeweb.com)
A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones. (news-medical.net)
Misfolded proteins are toxic to cells. (phys.org)
Then his team conducted further experiments to pinpoint changes in the activity of these proteins in various kinds of human cancer cells and in mouse models. (sciencedaily.com)
ERAP1 codes for a molecule that processes microbial proteins in white blood cells. (nih.gov)
However, there has been a resolution gap between a cell's smallest structures, such as the cytoskeleton that supports the cell's shape, and its largest structures, such as the ribosomes that make proteins in cells. (bigthink.com)
From the 1940s to 1960s, biochemists worked to separate cells into their molecular components and learn how to determine the 3D structures of proteins and other macromolecules at or near atomic resolution. (bigthink.com)
Researchers have used this approach, for example, to show how proteins move and are degraded inside an algal cell . (bigthink.com)

Over the years, dedicated sickle cell disease programs and research initiatives have greatly improved patient care and life expectancy. (newswise.com)
To develop SCD, a newborn must receive two copies of the sickle cell gene or sickle cell trait (SCT) from their parents. (medicalnewstoday.com)
People with one sickle cell gene carry SCT, which typically does not cause severe disease. (medicalnewstoday.com)
SCD affects cells so that they become crescent- or sickle-shaped instead of being rounded, and they become less rigid than those in people without the condition. (medicalnewstoday.com)
Sickle cell disease usually presents in babies at birth. (medicalnewstoday.com)
This is in contrast to the other options listed - Cystic Fibrosis, Sickle Cell Disease, and Colorblindness - which can all be present from birth or develop early in life. (proprofs.com)
Sickle cell disease is not caused by nondisjunction in meiosis. (proprofs.com)
these include relatively rare heritable diseases like cystic fibrosis and sickle cell disease, along with many others. (cdc.gov)
Inducing fetal hemoglobin (HbF) in red blood cells can alleviate ß-thalassemia and sickle cell disease. (cdc.gov)
Data from two pivotal trials suggest that a single infusion of the CRISPR-based gene therapy exagamglogene autotemcel (exa-cel) can provide a 'functional cure' for patients with transfusion-dependent beta-thalassemia or severe sickle cell disease. (cdc.gov)
Ex vivo therapies have focused on blood disorders, including at least 6 trials aiming to cure sickle cell disease (SCD) or transfusion-dependent ß-thalassemia (TDT). (cdc.gov)

Rearranged during transfection (RET), kinase alterations, which include fusions and activating point mutation, lead to overactive RET signaling and uncontrolled cell growth. (medscape.com)
A mutation on this gene also affects how your cells grow and spread. (webmd.com)
ATSDR reviewed medical records and conducted genetic testing for the JAK2V617F mutation to confirm the PV diagnosis. (cdc.gov)
In 2005, researchers identified a genetic mutation in most PV patients. (cdc.gov)
In a genetic analysis of 310 Labradors, the researchers found that 23 percent of them had a mutation in the POMC gene, which they think is responsible for producing two compounds essential for telling the dogs when they've had enough. (discovermagazine.com)
The researchers searched for the genetic mutation in 38 other species of dog, but found it in only one, flat coat retrievers, a close relative of Labs. (discovermagazine.com)
Anything for a Treat The dogs with the genetic mutation also responded more strongly to food - they begged for a treat more often and paid greater attention at mealtimes. (discovermagazine.com)

Scrutinizing the first days of development in abnormal embryonic stem cells, researchers have uncovered a basic mechanism underlying fragile X syndrome, the most common inherited cause of mental retardation in boys. (sciencenews.org)
Researchers have identified a rare genetic syndrome characterized by intellectual disability, seizures, an abnormal gait and distinctive facial features. (news-medical.net)
ROS-1 gene alterations, thought to lead to abnormal cells, have been identified in various cancers, including NSCLC. (medscape.com)
Nondisjunction in meiosis can lead to an abnormal number of chromosomes in the resulting cells, which is the cause of Down syndrome, Turner's syndrome, and Klinefelter's syndrome. (proprofs.com)
Loss of DICER1 in the airway lining cells could disrupt this communication, possibly setting the stage for abnormal growth. (scienceblog.com)
MGUS is a benign condition in which an individual has abnormal plasma cells in the bone marrow. (healthline.com)
In solitary plasmacytoma, abnormal plasma cells are found to be concentrated in a single tumor called a plasmacytoma. (healthline.com)

At present, this is only possible with mice, using so-called embryonic stem cells. (newscientist.com)
The researchers found that the mice didn't develop tumors, even after more than a year. (the-scientist.com)
To test whether adult mice can regain this ability, the researchers crushed the optic nerves of some mice and induced glaucoma in another set of mice by inserting tiny beads into their eyes, then injected the virus encoding the three transcription factors into all the mice's eyes. (the-scientist.com)
The majority of studies on cancer stem cells have been carried out in vitro or in immunodeficient mice models, which do not account for a fully functioning immune response. (newkerala.com)
The team also demonstrated that supplementing the mice inoculated with cancer stem cells with a molecule called nicotinamide mononucleotide resulted in the proliferation of non-senescent macrophages and reduced the immunosuppressive factors produced by senescent macrophages, preventing tumour growth and leading to increased survival times in mice. (newkerala.com)
Researchers have identified a pathway between the brain and the immune system in mice that may explain why psychological stress can worsen gut inflammation . (newscientist.com)
The researchers then performed a colonoscopy on the mice and rated gut inflammation and intestinal damage between 0 and 15, with higher scores indicating worse outcomes. (newscientist.com)
They found that mice with persistently elevated glucocorticoids had changes in specialised neural cells called enteric glia. (newscientist.com)
In this study, researchers examined what happens when mice breathe in carbon nanotube s. (cdc.gov)
In a study published in Nature Metabolism, Tune H Pers and his colleagues identified several cell populations in the brainstem that control the energy balance of mice. (lu.se)
When we activated two of those cell populations, mice with a predisposition to obesity reduced their eating. (lu.se)

But recent work published in the journals Mitochondrion and BMC Molecular and Cell Biology by Aloka Abey Bandara, a research associate professor in the Department of Biomedical Sciences and Pathobiology in the Virginia-Maryland College of Veterinary Medicine , and his team offers mitochondrial disease patients and their parents a glimmer of hope. (mitoaction.org)
this topic is an extremely active area of cell biology research. (medscape.com)
Dr Peter Czabotar , Professor Peter Colman and colleagues in the institute's Structural Biology division , together with Dr Dana Westphal from the institute's Molecular Genetics of Cancer division , made the discovery which is published in the latest edition of the journal Cell . (edu.au)
What happens when you mix a group of tumor biology researchers with software developers and AI researchers? (lu.se)

Lymphoma is the most common blood cancer, but the diagnosis belies a wildly diverse and little understood genetic foundation for the disease that hampers successful treatment. (news-medical.net)
Researchers in the UNC School of Medicine have developed an AI model that can predict whether or not cancerous tissue has been fully removed from the body during breast cancer surgery. (newswise.com)
Chinese researchers, looking for a cure to lung cancer, inject the first ever Crispr-edited cells into a human being. (lifeboat.com)
The finding offers a new route toward therapies that can thwart the altered genetic pathways that allow cancer cells to proliferate and spread. (sciencedaily.com)
Wang, a member of the UNC Lineberger Comprehensive Cancer Center, studies how alternative splicing happens in normal cells and in cancer cells. (sciencedaily.com)
Wang's group also found that RBM4 played a role in controlling another splicing regulator called SRSF1, which is highly expressed in some cancer cells. (sciencedaily.com)
The cancer begins in squamous cells, the flat cells that line the inside of the lung airways. (webmd.com)
ice with healthy immune systems are exposed to cancer stem cells, which cause macrophage ageing and tumour growth. (newkerala.com)
A variety of cells, the most significant of which are cancer stem cells, make up malignant tumours. (newkerala.com)
Finding cancer stem cell biomarkers and creating treatments that specifically target these cells have been the main goals of research. (newkerala.com)
A group of researchers at Hokkaido University's Institute for Genetic Medicine, under the direction of Associate Professor Haruka Wada, looked into the ways in which cancer stem cells avoid the immune system in mouse models. (newkerala.com)
It was demonstrated that cancer stem cells cause macrophages, which are immune cells in charge of the initial stage of cancer cell death, to undergo senescence. (newkerala.com)
The lack of effectiveness of cancer stem cell-targeting drugs indicates that the immune response or lack thereof is more important than previously considered. (newkerala.com)
The team used two cell lines of glioblastoma tumour, one of which was capable of inducing tumour formation (cancer stem cell) and the other of which was not. (newkerala.com)
further investigation showed that macrophages cultured with cancer stem cells exhibit senescence or cellular ageing. (newkerala.com)
The team identified interleukin 6 (IL-6) produced by cancer stem cells as the molecule responsible for triggering these effects. (newkerala.com)
Cancer begins when healthy cells change and grow out of control. (cancer.net)
Although the causes of esophageal cancer aren't completely understood, researchers do know that certain factors can place someone at an elevated risk for developing the condition. (moffitt.org)
Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions. (edu.au)
Insufficient cell death can cause cancer by allowing cells to become immortal while excessive cell death of neurons may be a cause of neurodegenerative conditions. (edu.au)
Similarly, agents that drive Bax into its active form could force immortal cells such as cancer cells to die, providing the basis for a potential new class of anti-cancer agents. (edu.au)
Cancer stems from mutated cells continually making copies of themselves inside an individual. (popsci.com)
If you had cancer, those cells would contain your own DNA, and when you died, your cancer would ( usually ) perish with you. (popsci.com)
Under normal circumstances, you wouldn't be able to transfer cancer to others, and unless researchers made a particular effort to preserve them , the cancerous cells would die too. (popsci.com)
At first, researchers suspected a virus was behind the cancer. (popsci.com)
Multiple myeloma is a cancer that affects plasma cells in the bone marrow. (healthline.com)
This is believed to be due to the accumulation of cancer-promoting genetic changes over an individual's lifetime. (healthline.com)
For cancer, this means better understanding how cancer cells survive, grow, and interact with therapies and other cells. (cancer.gov)
Dr. Nilsson focuses on how genetic variation influences blood cell formation and blood cancer risk. (lu.se)
Basal cell carcinoma (BCC) is a nonmelanocytic skin cancer (ie, an epithelial tumor) that arises from basal cells (ie, small, round cells found in the lower layer of the epidermis). (medscape.com)
Håkan Axelson's research group is part of the large EU-funded KATY project, which focuses on the most common type of kidney cancer, clear cell renal cell carcinoma, which is one of the ten most common types of cancer worldwide. (lu.se)
Hopefully, with the help of AI, they can connect a multitude of data that leads to new treatments for kidney cancer - that's at least what the researchers in the EU-project KATY envision. (lu.se)
The engineers and AI researchers need to understand what our biological information consists of, and we cancer researchers need to understand what AI can do. (lu.se)
The focus is on the most common type of kidney cancer, clear cell renal cell carcinoma, which is one of the ten most common types of cancer worldwide. (lu.se)
It is a well-documented form of cancer that researchers have extensive knowledge about. (lu.se)

The research also highlights the value of embryonic stem cells for studying genetic diseases, says Yang Xu, a stem cell researcher at the University of California, San Diego. (sciencenews.org)
The new technique means they will not need embryonic stem cells. (newscientist.com)

He has made important contributions to our understanding of genetic predisposition for hematologic malignancies, the genetic regulation of immunoglobulin levels, and the computational analysis of genomics data. (lu.se)
The researchers found that four of those cell populations were associated with genetic obesity predisposition. (lu.se)
Tune H Pers receives the Leif C. Groop Award for Outstanding Diabetes Research in 2024 for research that has increased the understanding of how specific brain areas and cell populations regulate glycemic control, energy homeostasis, and genetic predisposition to obesity. (lu.se)

Mitochondrial diseases are a group of debilitating genetic disorders that affect one in 5,000 people throughout the world, most of them being children. (mitoaction.org)
Judge's research focuses on genetic diseases of the heart and skeletal muscle. (ucsfhealth.org)
A structural component of brain cells, tau has also been linked to Alzheimer's and Parkinson's diseases. (medlineplus.gov)
How can we use viruses to fight genetic diseases? (lu.se)

It has long been known that the thyroid influences cardiac function and cardiac arrhythmias," says study senior author Dr. Geoffrey W. Abbott, associate professor of pharmacology in medicine at Weill Cornell Medical College, "but our findings demonstrate a novel genetic link between inherited cardiac arrhythmia and thyroid dysfunction. (sciencedaily.com)
National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics. (nih.gov)
While the researchers think their findings may someday lead to new therapies for conditions induced by stroke or oxygen-scarce environments, such as underwater and high altitudes, algae are far from ready to enter our blood circulation. (scitechdaily.com)
By showing that the gene acts similarly in both man and his best friend, researchers may be able to translate their findings to humans. (discovermagazine.com)
The findings presented here can guide researchers establish appropriate experimental design for muscle stem cell genetic studies. (bvsalud.org)
Researchers from all around the world are able to share their findings. (cdc.gov)
We can share our unique findings with other researchers across the world. (cdc.gov)
It works with researchers from many top institutions, and through the Registry we are able to share key findings that will benefit other research projects. (cdc.gov)

After getting IRB approval to return genetic test results to participants, researchers can order spit kits online from 23andMe, and send them to participants' homes or to the study site. (genomeweb.com)
A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy. (genomeweb.com)
A new study has revealed insights into how cells sense and respond to the weightlessness experienced in space. (phys.org)
Each of the genetic factors may contribute a little to the overall risk of disease," said Elaine F. Remmers, Ph.D., staff scientist in NHGRI's Inflammatory Disease Section and study co-author. (nih.gov)
To be able to study the blood vessels in the inner auditory organ, the researchers used a synchrotron system. (hearingreview.com)
In a study published in Toxicological Sciences , researchers tested the effects of five drugs (including caffeine and the blood thinner warfarin) on the growth of zebrafish embryos. (scitechdaily.com)
Zebrafish embryos are transparent and grow outside the mother, so we can monitor the behavior of live cells as they develop," said Toru Kawanishi, project assistant professor at the University of Tokyo's Department of Biological Sciences at the time of the study. (scitechdaily.com)
A risk of using Yamanaka factors in vivo is that dedifferentiation can cause cells to divide rapidly, so researchers in the Cell study only turned them on in short bursts. (the-scientist.com)
In a June study conducted by UC Davis and Cornell plant biologists, researchers gained new insight into these differences. (theaggie.org)
And ongoing development of one particular technique, cryo-electron tomography, or cryo-ET , has the potential to deepen how researchers study and understand how cells function in health and disease. (bigthink.com)
Historically, this squid has been important for neurobiologists because it has a giant, easy-to-study nerve cell. (npr.org)
For example, a decade ago researchers from Macquarie University conducted a study that was "the first to. (icr.org)
A new study has found genetic makeup does not predispose people to tooth decay, however the research did. (edu.au)
The study was published in the journal Cells . (who.int)
The objective of this study is to isolate and characterize stem cells from the pulp of permanent third molars and analyze the cells obtained in terms of their morphology and chondrogenic, osteogenic and adipogenic cell differentiation. (bvsalud.org)

In a report published this week (Nov. 8, 2017) in Science Advances , researchers from the University of Wisconsin-Madison detail a defined, step-by-step process to make a more exact mimic of the human blood-brain barrier in the laboratory dish. (wisc.edu)

Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. (news-medical.net)

A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers. (news-medical.net)
Myeloproliferative neoplasms (MPN) are a group of blood cancers where the bone marrow makes too many blood cells. (cdc.gov)
Unlike normal cancers, these cells don't share the same genetic code of the animals they infect. (popsci.com)

Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy (DMD). (news-medical.net)
The team focused on a specific genetic marker for a group of cells involved in craniofacial development in both mammals and fish. (scitechdaily.com)
Research from 2011 found differences in specific genetic events between males and females with multiple myeloma. (healthline.com)

Using an innovative genetic ablation and multi-omics profiling strategy, the researchers documented the highly complex molecular and phenotypic programmes dependent on the Smarca5 gene. (who.int)
Ever since its introduction as a genetic tool, the Cre-lox system has been widely used for molecular genetic studies in vivo in the context of health and disease, as it allows time- and cell-specific gene modifications. (bvsalud.org)

Researchers repaired what is otherwise irreversible damage in the animals' ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells. (the-scientist.com)
The team focused on retinal ganglion cells (RGCs), which are neurons whose axons make up the optic nerve and snake their way into the brain, transmitting information from light-sensitive photoreceptors. (the-scientist.com)
Glial cells help maintain neurons and communicate with many different types of cells, and they respond to stress hormones by pumping out inflammatory molecules . (newscientist.com)
Genetic analysis also revealed that stress alters neurons in the gut, making them appear less mature. (newscientist.com)

UNC Health Care and the UNC School of Medicine have launched a tool for media to request interviews with experts and researchers at the forefront of the global Zika research initiative. (newswise.com)
Current research includes investigating the role of immune cells in decompression sickness using lung-on-a-chip devices, developing "bottom-up" multifunctional magnetic microrobots, and using acoustically responsive particles for capture and purification of disease biomarkers. (wikipedia.org)
Judge is a member of the American Academy of Pediatrics and International Society for Stem Cell Research. (ucsfhealth.org)
Cryo-electron tomography, or cryo-ET, is the future of cell research. (bigthink.com)
If you would like to give to a specific research program or support the work of a particular researcher, contact our fundraising team today. (edu.au)
As well as explaining the detail of how cell death occurs, our research could provide clues about how to design potential new therapeutic agents that target Bax," Dr Czabotar said. (edu.au)
Much of what's known about how nerve cells send electrical signals comes from studies of this cell, and the research led to a Nobel prize in 1963. (npr.org)
By identifying specific chemical molecules that can chaperone the cells through the various stages of development to become the brain endothelial cells, the Wisconsin team, in effect, provides a recipe to standardize making the cells in quantities useful for research and things like high-throughput drug screens. (wisc.edu)
Understanding what leads to brain cell death at the most fundamental level will surely allow new therapeutic strategies to be developed," said Dr. Dietrich Stephan, Director of TGen's Neurogenomics Division and Deputy Director of Discovery Research. (tgen.org)
Two MCRI researchers have been recognised by the National Health and Medical Research Council (NHMRC) with. (edu.au)
Dr Ken Pang is a Senior Research Fellow, consultant paediatrician and biomedical researcher. (edu.au)
Research from Lund University Diabetes Centre has described what epigenetic changes occur in fat cells in connection with physical activity. (lu.se)
Over the course of the day, researchers from the Center will showcase their cutting-edge research, provide insights into their daily work, and explain the mechanisms behind scientific breakthroughs by offering lessons, group discussions, practical workshops, and laboratory visits. (lu.se)
The diabetes researcher at the University of Copenhagen is now awarded the LUDC Leif C. Groop award for his research on obesity and type 2 diabetes. (lu.se)
His groundbreaking research combines genetic data, single-cell technologies and machine learning and could lead to new treatments for patients with obesity or type 2 diabetes. (lu.se)
Muscle stem cells are required for skeletal muscle growth, regeneration and to delay muscle disease progression, hence providing an attractive model for stem cell research. (bvsalud.org)

Genetic ablation of SMN or small interfering RNA-base knockdown of SMN expression aggravated the tubular injury and interstitial fibrosis. (bvsalud.org)
In genetic ablation studies lacking proper controls, this inherent defect could be misinterpreted as being provoked by the deletion of the factor of interest. (bvsalud.org)

Researchers then compared SNP differences between people with and without disease. (nih.gov)
The exact cause of craniofacial differences is not fully understood, but researchers currently think that multiple factors may be involved. (scitechdaily.com)
Specifically, researchers isolated segments of DNA where expression would result in differences in color or fruit quality. (theaggie.org)
The researchers theorized that these differences could influence further genetic changes that contribute to multiple myeloma. (healthline.com)

In this way, they can identify different cell types, investigate changes in gene expression patterns, or detect genetic variations among different cells. (lu.se)

These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical and biological processes. (mitoaction.org)
The main advance is we now have a fully defined process that uses small molecules to guide cells through the developmental process," says University of Wisconsin-Madison Professor of Chemical and Biological Engineering Sean Palecek of the method that substitutes chemical factors for cells to push stem cells to become the brain endothelial cells that compose the blood-brain barrier. (wisc.edu)
To develop the new method for making the cells, Palecek collaborated with the laboratory of UW-Madison chemical and biological engineering Professor Eric Shusta . (wisc.edu)

These newly discovered genetic associations provide a link between Behcet's disease and other more common illnesses, and thereby suggest new therapies for Behcet's disease. (nih.gov)
Akouos is developing targeted adeno-associated viral vector (AAV)-based gene therapies for sensorineural hearing loss, which results from dysfunction or damage to sensory cells and/or nerve fibers of the inner ear. (hearingreview.com)
By exposing cells to various agents, researchers can assess toxicity and effect of promising therapies. (wisc.edu)
To gain insight into pathological mechanisms and lay the potential groundwork for developing targeted therapies, we characterized the neurophysiologic and cell-type-specific transcriptomic consequences of a mouse model of HNRNPU haploinsufficiency. (bvsalud.org)

Delayed cell division can be a signal that the cell should undergo self-destruction. (medlineplus.gov)

The amount of information gathered via next-generation sequencing has made the diagnosis of genetic disorders quicker and more accessible to clinicians than ever before, but with expanded testing options come questions about ordering the correct type of testing. (news-medical.net)

Before cells divide, they must copy all of their chromosomes. (medlineplus.gov)
They tell the cell what to do and how to divide, which is the way cells multiply. (webmd.com)
This causes cells to live too long, divide, and spread. (webmd.com)
This gene plays a role in how your cells grow and divide. (webmd.com)
In multiple myeloma , these cells grow and divide out of control, leading to tumors in the bones . (healthline.com)

Building upon that work, she and her colleagues figured out how to inject gene-altering materials into the fertilized egg, to disrupt a gene involved in coloring the squid's skin and eye cells. (npr.org)

Instead, CTVT spreads between dogs by the transfer of cancerous cells themselves. (popsci.com)
And more than a dozen strains of cancerous cells drift in seawater , infecting several species of mussels and clams. (popsci.com)

This means that individuals with this blood type have both the A and B antigens on their red blood cells. (proprofs.com)
Sixty percent of cases express 1 or more T-cell antigens (CD3 + , CD43, or CD45RO). (medscape.com)

Lange and his colleagues analyzed genetic sequences from nine commercial cannabis strains and found distinct gene networks orchestrating each strain's production of cannabinoid resins and terpenes, volatile compounds behind the plant's powerful aroma. (phys.org)
From nearly 800,000 SNPs, researchers detected and mapped a small number that are found in those who have Behcet's disease at a significantly higher rate than in those without the disease, suggesting that the variant or another one nearby contributes to the disease. (nih.gov)
Researchers found age-related hearing loss is related to a decrease in inner-ear cholesterol, and that supplements could address the issue. (hearingreview.com)
They found that all five had the same effect, impairing the migration of bone-forming cells which resulted in the onset of facial malformation. (scitechdaily.com)
This had the positive side effect of making these dogs easier to train, the researchers found. (discovermagazine.com)

Researchers suspect that other genetic and environmental factors may be involved. (medlineplus.gov)
Named for the Turkish physician who described it in 1937, Behcet's (pronounced BET'-chets) disease is triggered by complex genetic and environmental factors, and causes inflammation of blood vessels in various parts of the body. (nih.gov)
These so-called Yamanaka factors, named after biologist Shinya Yamanaka, are widely used to generate induced pluripotent stem cells (iPSCs). (the-scientist.com)
while the proliferation of T cells was unchanged, their antitumor activity was suppressed due to the immunosuppressive factors produced by senescent macrophages. (newkerala.com)
In a recent commentary , McCarthy and Birney argue that these studies can provide an evidentiary path to personalized medicine - but only if they are done in diverse populations, and integrate rare and common genetic risk factors with measurements of changing environments and health indices over time. (cdc.gov)
Genetic and non-genetic risk factors interact in ways that can often be hard to measure, much less integrate in a way that informs risk estimates. (cdc.gov)

A year ago, we showed that you could do it with cells from embryos," says Wilmut. (newscientist.com)
Particularly valuable animals could be cloned from adult cells without the uncertainties of crossing them with other animals or tinkering with embryos. (newscientist.com)
These fluorescent images of live zebrafish embryos show the movement, assembly, and growth of cartilage-forming cells at 48, 72, and 96 hours post-fertilization. (scitechdaily.com)

In studies of identical twins, researchers from Lund University have identified mechanisms that could be behind the development of type 2 diabetes. (lu.se)

Conceivably, the mutated cells do not turn into tumors themselves. (scienceblog.com)
These tumors can crowd out healthy blood cells, leading to the symptoms associated with multiple myeloma like bone pain and bruising easily. (healthline.com)

We show that consistently the Pax7-CreERT2 allele targeted into the Pax7 coding sequence (knock-in/knock-out allele) produces an inherent defect in regeneration, manifested as delayed post-injury repair and reduction in muscle stem cell numbers. (bvsalud.org)

NIH researchers identify new gene variants associated with risk for complex inflammatory syndrome. (nih.gov)

Using induced cells, adult cells from patients, which are reprogrammed to an embryonic stem cell-like state, will also allow researchers to better understand the etiology and progression of a variety of neurological disorders. (wisc.edu)
Experimental stem cell transplant therapy may hold promise for patients with a speciﬁc type of multiple sclerosis (MS). Patients who received the treatment did not experience a relapse of MS symptoms, progression of disability, or new brain lesions for ﬁve years. (medlineplus.gov)

Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells. (medindia.net)
The two most significant physical problems in brain cells affected by Alzheimer's Disease are neuritic plaques and NFTs. (tgen.org)

These reports provide foundational information about SEED for other researchers, policymakers, and clinicians. (cdc.gov)

Bone- and cartilage-forming cells in the head, called cranial neural crest cells (CNCCs), generally move a long distance from where they are first formed around the back of the neck, to their intended destinations such as the jaw or nose," explained Kawanishi. (scitechdaily.com)

[ 3 ] This ultrastructural component of cellular architecture is involved fundamentally in intracellular and cell substrate interactions and signaling via its role in cell morphology and movement. (medscape.com)
Analysis of the cellular phenotype showed that the cells were negative for CD45, CD69, CD117 and HLADR, and positive for CD13, CD44, CD73, CD90 and CD105. (bvsalud.org)

The signs and symptoms of Roberts syndrome may result from the loss of cells from various tissues during early development. (medlineplus.gov)
He employs an approach called "disease modeling in a dish," which involves growing human cell types and tissues in the laboratory. (ucsfhealth.org)
Stem cells are cells with a low degree of differentiation that have the capacity to reproduce and can generate differentiated cells of several different types of tissues 1 . (bvsalud.org)

Now that we can see how Bax changes its shape to move from the inactive to the active form, it may be possible to block Bax activation, to prevent cell death in conditions such as neurodegenerative disorders, where illness is caused by excessive cell death. (edu.au)
This condition is rare, making up only about 2 to 5 percent of all plasma cell disorders. (healthline.com)
PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)

UniStem Day is the largest educational outreach initiative on stem cells and regenerative medicine in Europe. (lu.se)

The team theorizes that something else must happen to the normal copy of DICER1 in lung cells for a tumor to develop. (scienceblog.com)
During lung development the cells that line the airways and the cells that make up the support structures have to communicate. (scienceblog.com)

Harvard Medical School geneticist David Sinclair and his colleagues aimed to reset the biological clocks of a group of cells to see if they could rejuvenate injured and aging cells. (the-scientist.com)
Just as it becomes easier to understand how complicated systems work when you know what they look like, understanding how biological structures fit together in a cell is key to understanding how organisms function. (bigthink.com)
They've evolved these big brains and this behavioral sophistication completely independently," says Joshua Rosenthal , a researcher at the Marine Biological Laboratory in Woods Hole, Massachusetts. (npr.org)

A link between the health of the brain tissue associated with cognitive functioning and the presence of dementia in Down's syndrome patients has been discovered by researchers at Sanders-Brown Center on Aging at the University of Kentucky. (medindia.net)

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. (genomeweb.com)

This zebrafish larva has been genetically modified so that the bone-forming cells in the face emit a green fluorescence. (scitechdaily.com)
We then treated them with chemicals that are known to cause facial defects in human newborns, and tracked the trajectories of the bone-forming cells throughout embryonic stages," explained Kawanishi. (scitechdaily.com)
We were surprised that regardless of how each chemical acts on cells molecularly, impaired migration of bone-forming cells in early development was responsible for the onset of facial malformation for all the five chemicals. (scitechdaily.com)
It develops from immature bone cells that normally form new bone tissue. (cancer.net)

The algae actually produced so much oxygen that they could bring the nerve cells back to life, if you will," says senior author Hans Straka of Ludwig-Maximilians-University Munich. (scitechdaily.com)
Straka was studying oxygen consumption in tadpole brains of African clawed frogs ( Xenopus laevis ) when a lunch conversation with a botanist sparked an idea to combine plant physiology with neuroscience: harnessing the power of photosynthesis to supply nerve cells with oxygen. (scitechdaily.com)
It affects nerve cells in the brain and spinal cord, causing nerves in the muscle to die. (cdc.gov)

At Harvard's Wyss Institute, Shields developed cytokine-releasing macrophage "backpacks" that maintain a tumor-killing state in cells, travel to tumor sites, and slow their growth. (wikipedia.org)

With the full launch of the service today, 23andMe announced it is collaborating with researchers at a number of institutions, including McMaster University/St. Joseph's Healthcare Hamilton, the University of California, San Diego, and Washington University in St. Louis. (genomeweb.com)
A team led by University of Iowa researchers has identified a gene linked to rare, often fatal kidney-related birth defects. (news-medical.net)
And Jonathan Slack, an embryologist at the University of Bath, says that it is dangerous to base big ideas on a single case of a lamb raised from an adult ewe cell. (newscientist.com)
When Some is Never Enough A team of researchers from the University of Cambridge in the U.K. says that they have discovered why some dogs seem to be shameless gluttons. (discovermagazine.com)

With their latest discovery, researchers have significantly advanced the understanding of how human cells protect themselves from constant and potentially destructive changes in gene expression. (news-medical.net)
They differ among other things with regard to their internal structure: Higher cells contain organelles that â€" like organs in the human body â€" serve special functions. (healthmedicinet.com)
A team of UW-Madison researchers has developed a tightly defined, step-by-step process to turn multipurpose stem cells (top) into the cells that make the human blood-brain barrier (bottom), the anatomical feature that protects our brain from toxins and other threats that may be in circulating blood. (wisc.edu)
Rudimentary models of the barrier have been created in the laboratory dish using human stem cells, but such models have depended on mixing a cocktail of cell types to elicit the complex chemical interplay that directs blank slate stem cells to become the endothelial cells that make up the blood-brain barrier. (wisc.edu)
In stem cell science, directing stem cells to become any of the hundreds of cell types that make up the human body is often as much art as science. (wisc.edu)
Human genetic diversity alters off-target outcomes of therapeutic gene editing. (cdc.gov)

Researchers are hoping to incorporate this into a clinical strategy to better manage treatment for athletes who suﬀer a concussion. (medlineplus.gov)

Researchers from the United Kingdom and France have identified four separate biochemical subgroups in a selection of cases of Creutzfeldt-Jakob disease. (news-medical.net)
The genetic associations have helped classify Behcet's disease with more common inflammatory conditions such as psoriasis, inflammatory bowel disease and a form of spinal arthritis called ankylosing spondylitis. (nih.gov)
the large (L) segment en- severity of disease caused by DOBV-Ap infections is more codes viral RNA-dependent RNA polymerase, the medium often moderate to severe. (cdc.gov)
The disease starts in cells that release substances, like mucus. (webmd.com)
But researchers have tracked the disease in 90 countries, on every continent except Antarctica. (popsci.com)
CRISPR gene editing holds great promise to modify DNA sequences in somatic cells to treat disease. (cdc.gov)
More researchers are studying the disease today, and technology continues to improve. (cdc.gov)

They then remove the original chromosomes from these to leave DNA-free cells. (newscientist.com)
Chromosomes are thread-like structures located inside the nucleus of cells that contain genetic information. (proprofs.com)

Anatomy11

Organisms6

Diseases1

Chemicals and Drugs18

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Psychiatry and Psychology20

Phenomena and Processes26

Disciplines and Occupations31

Anthropology, Education, Sociology and Social Phenomena27

Technology, Industry, Agriculture3

Humanities16

Information Science64

Named Groups5

Health Care69

Geographicals5

Mutations13

Tumor cells5

Genome9

Scientists21

Postdoctoral researcher1

Genes21

Protein23

Disorder6

Proteins12

Sickle11

Mutation7

Abnormal7

Mice11

Biology4

Cancer35

Embryonic stem2

Predisposition3

Diseases4

Findings8

Study15

20171

Cystic fibrosis1

Cancers3

Specific genetic3

Molecular2

Neurons4

Research16

Ablation2

Differences4

Variations1

Chemical and biological3

Therapies4

Undergo1

Diagnosis1

Divide5

Disrupt1

Cancerous cells2

Antigens2

Found5

Factors6

Embryos3

Diabetes1

Tumors2

Defect1

Variants associated1

Progression2

Alzheimer's2

Clinicians1

Neural crest1

Cellular2

Tissues3

Disorders3

Regenerative medicine1

Lung2

Biological3

Syndrome1

Advances1

Bone4

Nerve cells3

Macrophage1

University4

Human6

Clinical1

Disease7

Chromosomes2