Research on human embryonic stem cells embryonic stem cells clone cells. Medical search. Frequent questions

Along the same lines, a writer in the Baltimore Chronicle accused "opponents of embryonic stem-cell research" of "prolonging the suffering of millions. (breakpoint.org)
He labeled the president, and other opponents of embryonic stem-cell research, as an "obstacle to hope for a scientific breakthrough, a miracle. (breakpoint.org)
Rep. Elijah Cummings, a Democrat, said that "opponents of embryonic stem cell research seem to have difficulty containing their glee" over the case of disgraced cloning researcher Hwang Woo-suk, who is now under investigation for fraudulent claims of human stem cell breakthroughs. (jpost.com)

After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
Up to 14 days a human blastocyst - the earliest stage of fetal development - consists almost entirely of pluripotent cells, which are those that could develop into the constitutive elements of any organ in the human body. (thetablet.org)
Stem cells were then derived from the inner cell mass of the blastocyst. (scienceblog.com)
The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (scienceblog.com)
A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)
From there, Dr. Brinster became interested in modifying the development of animals and their germ lines, and he went on to become the first person to show that it was possible to colonize a mouse blastocyst with stem cells from older embryos. (avma.org)
Moreover, Dr. Brinster first demonstrated that teratocarcinoma cells could combine with blastocyst cells to form adult chimeric mice, establishing the feasibility of this approach to change the genetic character of mice. (avma.org)

The Threat of Human Cloning concludes by calling for laws prohibiting both human cloning and the creation of embryos for research. (thenewatlantis.com)
China enacted regulations early this year to allow the cloning of human embryos for research, and South Korea enacted similar legislation to allow research days ahead of the February announcement. (publicintegrity.org)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)

The most famous clone was a Scottish sheep named Dolly. (medlineplus.gov)
Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
Dolly the sheep was cloned in 1996. (thetablet.org)
The cloning of Dolly the sheep at the Roslin Institute and the cultivation of human embryonic stem cells at Johns Hopkins and at the University of Wisconsin intensified an already fractious debate. (powells.com)
At the appropriation hearings to fund the NIH that followed the birth of Dolly, Varmus gave an impromptu, unscripted talk about stem cells, cloning and cell biology to a rapt audience. (powells.com)
When the world learned in 1997 of Dolly the sheep, the first clone produced from an adult mammal, a broad public discussion about the ethics of human cloning ensued, largely focused on the nature, meaning, and future of human procreation. (thenewatlantis.com)
Several western scientists have been conducting their research in Asian countries in the past few years, including Cibelli, formerly of Advanced Cell Technology, an early U.S. pioneer of embryo research, as well as Alan Colman, now located in Singapore, one of the scientists who helped create the first mammalian clone, the sheep Dolly. (publicintegrity.org)
With the announcement last November that Ian Wilmut, who cloned Dolly the sheep, was ditching cloning in favor of the "amazingly efficient" method of induced pluripotent stem-cell research (iPS) - which reprograms adult stem cells into embryonic ones without using human embryos or eggs - pro-lifers had reason to celebrate. (crisismagazine.com)
Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)

Researchers hope to use these cells to grow healthy tissue to replace injured or diseased tissues in the human body. (medlineplus.gov)
There is nothing in the policy that stops researchers from using stem cells obtained elsewhere, like adult stem cells. (breakpoint.org)
The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
A six-person review committee consisting of stem cell researchers, an editor from the journal Nature, and members of the Science editorial boad determined that the editors of Science followed the correct review procedures at the time the papers were published. (lifenews.com)
Before patient-specific stem cells can potentially be used in the clinic, a variety of issues must be addressed, the researchers emphasized. (scienceblog.com)
In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. (scienceblog.com)
From the 185 donated oocytes, endowed with the genetic material from a different person (or in one case, the same person), the researchers report development of 31 hollow balls of cells called "human nuclear-transfer blastocysts. (scienceblog.com)
The researchers generated these stem cell lines ten times more efficiently than in their 2004 Science study, using improved laboratory methods. (scienceblog.com)
Such "guidelines" will ensure that stem cell researchers are not treated poorly as was Hwang when he was eventually found guilty of falsifying his data. (lifeissues.net)
In the first report [2], researchers from Edinburgh and Oxford took cells from the mouse brain marked with transgene 1, and cultured them together with ES cells marked with a second transgene, 2. (i-sis.org.uk)
These researchers pointed out that the spontaneous fusion rate (without interleukin-3) was extremely low, between 2-11 per million bone marrow cells, and is unlikely to account for all the findings with adult stem cells. (i-sis.org.uk)
In the current issue of the same journal [6], researchers compared the frequency and type of mutation induced in embryonic stem cells and embryonic somatic cells. (i-sis.org.uk)
hero" is the right word for how Hwang Woo-suk is revered by the media -- and by a large section of the Korean public who have bought into the false promises of embryonic stem cell and cloning researchers. (blogspot.com)
A Korean television station whose investigative report was the nail in the coffin that prompted human cloning scientist Hwang Woo-suk to admit he lied about egg donations his researchers made says he may have lied about the results of his research as well. (blogspot.com)
The researchers of the paper from Advanced Cell Technology, collaborated with scientists from the Institute of Regenerative Medicine at Wake Forest University School of Medicine, Winston-Salem, North Carolina, and the University of Chicago, Chicago, Illinios. (news-medical.net)
Then in 1970 he took a scientific faculty position at the University of California at San Francisco, where researchers such as J. Michael Bishop and Herbert Boyer were doing groundbreaking research in molecular biology. (powells.com)
Chinese scientists at various research institutions have reported successful experiments in human cloning, including the production of human-rabbit hybrid embryonic stem cells, according to the claims of Professor Lu Guangxiu at Xiangya Medical College, who told the Wall Street Journal in March of 2002 that researchers at the College had been successfully cloning embryos for two years. (publicintegrity.org)
While an international framework to regulate cloning remains stalled in the United Nations, some Asian countries are offering more stable climates for researchers to pursue their work. (publicintegrity.org)
Below you can see some examples of the infrastructure for research on genes and cells, available for researchers at Lund University. (lu.se)

By destroying the most basic human bond of all-that between mother and child-abortion dissolves the precious glue that binds our nation together. (lifenews.com)
2 Furthermore, the National Cancer Institute commissioned a study lead by Dr. Janet Daling, an abortion supporter, and her colleagues at the Fred Hutchinson Cancer Research Center which found a link between abortion and cancer: "among women who had been pregnant at least once, the risk of breast cancer in those who had experienced an induced abortion was 50% higher than among other women. (lifenews.com)
A House Democrat has filed an amendment to the state budget that would bar the use of Department of Corrections funds for abortion, cloning or stem cell research. (missourinet.com)
The House has given first round approval to legislation meant to allow medical workers in Missouri refuse to participate in certain procedures including abortion, human cloning and stem cell research if they have a religious or moral objection to them. (missourinet.com)
Public funding of abortion or embryonic stem cell research. (iowacatholicconference.org)
They highlighted five "non-negotiable" items for voters to consider: abortion, euthanasia, embryonic stem call research, human cloning and gay marriage. (americamagazine.org)
The way I vote now is to look at the issues, starting with the five non-negotiables: Abortion, Euthanasia, Embryonic Stem Cell Research, Human Cloning, and Same-Sex Marriage. (lifesitenews.com)

It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)

Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)
The copied material, which has the same genetic makeup as the original, is referred to as a clone. (medlineplus.gov)
These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
Genetic match for the patient - you use their skin cells. (cbc-network.org)
Recent experimentation that has cultured lab-grown monkey embryos for up to 20 days and the possibility of creating human-monkey chimeras - beings that contain genetic codes from two different species - has further pushed the envelope on embryonic stem cell research. (thetablet.org)
Each of the 11 new human embryonic stem cell lines was created by transferring the nuclear genetic material from a non-reproductive cell of a patient into a donated egg, or "oocyte," whose nucleus had been removed. (scienceblog.com)
In their new paper, Science author Woo Suk Hwang from Seoul National University in Seoul, Korea and colleagues replaced the nuclei from donated oocytes with nuclei from skin cells from male and female patients, ranging in age from 2 to 56, who had spinal cord injuries, juvenile diabetes and the genetic disease "congenital hypogamma-globulinemia. (scienceblog.com)
The science fiction definition of "clone" suggests that the cloned organism would be an exact genetic copy of another creature-human or beast-created in the laboratory by any of a number of means. (all.org)
These biobanks are important for conducting research that integrates genetic and environmental factors. (technavio.com)
This form of genetic engineering would deny the children it produces an open future, burdening them with the expectation that they will be like the individuals from whom they were cloned. (thenewatlantis.com)
And cloning could make possible still more dramatic forms of genetic engineering. (thenewatlantis.com)
Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
UNESCO development of national ethics committees (NECs) and also reflected on recent surveys, including the 2014 NEC establish effective mechanisms of regional harmonization survey, and the 2009 UNESCO regional Legal survey, which and cooperation to address emerging issues related to bio- covered 10 issues related to medical and genetic research in ethics. (who.int)
A clone is an organism that is a genetic copy of an existing one. (who.int)
5. Most countries in the African Region have no specific regulations and policies governing genetic manipulations for assisted conception, treatment and research. (who.int)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)

In short, the remaining ethical barriers that preserve human dignity and God's rights in Creation are steadily coming down. (lifenews.com)
Established in 2010 at the request of Archbishop Philip Hannan, The BDF Hannan Institute is an educational outreach in service of educating medical students, law students and post-doctorate scientists to incorporate principles of human dignity in their professions and to engage in the law and policy debate with the goal of restoring the human right to life. (bdfund.org)
The Iowa Catholic Conference's legislative agenda was formulated in consultation with its Human Life and Dignity Committee and Education Committee, and was approved by the Iowa Catholic Conference board of directors. (iowacatholicconference.org)
As Pope Francis reminds us, "The dignity of each human person and the pursuit of the common good are concerns which ought to shape all economic policies. (iowacatholicconference.org)
It is in this spirit we reiterate our Catholic tradition that teaches that health care is a natural human right, essential to protecting human life and dignity. (iowacatholicconference.org)
The Vatican document "Dignitas Personae" ("The Dignity of a Person") warns that certain recent developments in stem-cell research, gene therapy and embryonic experimentation violate moral principles and reflect an attempt by man to "take the place of his Creator. (thetablet.org)
There will always be some people who will be trying to push the boundaries for their own interests, aware or unaware that they are pushing beyond what is for the common good or in keeping with human dignity," she said. (thetablet.org)
Michael Cook edits BioEdge, a bioethics newsletter, and MercatorNet, an on-line magazine whose focus is human dignity. (bioedge.org)
The Church is not a political organism, but as you hopefully have learned in the US Bishops Faithful Citizenship material (which we have made widely available to you in the parishes, in the Compass and on-line), the Church has the responsibility to speak out regarding moral issues, especially on those issues that impact the "common good" and the "dignity of the human person. (catholicherald.org)
These are areas that are "intrinsically evil" and cannot be supported by anyone who is a believer in God or the common good or the dignity of the human person. (catholicherald.org)
Work is so critical to the family and to the sense of human dignity. (catholicherald.org)
Considered contrary to the moral law, since (it is in) opposition to the dignity both of human procreation and of the conjugal union. (wikiquote.org)
Cultural and political clashes centering on the dignity of human life continue to intensify, as emerging medical technologies bring a dizzying array of new products and services to the marketplace. (catholicculture.org)
He acknowledged the "stupendous progress" of scientific research while issuing a grave warning that their new "domination" of the "forces of nature" was beginning to degrade the dignity of the very "transmission of life. (catholicculture.org)
The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)
related research and developments should therefore be carefully monitored and assessed, and the rights and dignity of patients respected. (who.int)

Scientists, many of whom are sold on utilitarian-based ethical analysis, try to downplay the issue of human life in stem-cell research. (catholicnewsagency.com)
"PrimeGen , based in Irvine, California, says that its scientists have converted specialised adult human cells back to a seemingly embryonic state - using methods that are much less likely to trigger cancer than those deployed previously. (cbc-network.org)
The company also claims to be able to produce reprogrammed cells faster and much more efficiently than other scientists. (cbc-network.org)
Many scientists today believe it is important to find meaningful ways to include the wider public in the discourse around various research practices. (thetablet.org)
I have been asked to comment on the latest news that scientists are now able to harvest embryonic stem cells without killing the embryo. (christianliferesources.com)
Chinese scientists have successfully created chimeric embryos containing a combination of human and pig cells. (bioedge.org)
Scientists announced this week that they have successfully produced embryonic stem cells by transferring the DNA of human skin cells into unfertilized human eggs to produce embryos, a technique the Church considers to be an abuse of human life. (womenofgrace.com)
Scientists at Stanford University in California have been able to coax embryonic stem cells into becoming eggs and sperm, which could one day lead to the creation of children through entirely artificial means. (womenofgrace.com)
British scientists are hailing the recent creation of human sperm cells that they believe could revolutionize fertility treatment. (womenofgrace.com)
Scientists have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury. (scienceblog.com)
The work also moves scientists one step closer to the goal of transplanting healthy cells into humans to replace cells damaged by diseases such as Parkinson's and diabetes. (scienceblog.com)
From the 31 nuclear-transfer blastocysts, the scientists derived 11 stem cell lines. (scienceblog.com)
Many scientists think that religion will always try to restrict legitimate scientific research, and will attempt to suppress any conclusion that disagrees with some group's theology. (equip.org)
It doesn't happen as often as it should, because scientists are human and change is sometimes painful. (todayinsci.com)
But his accounts of setting priorities for research, using science to set policy, handling scandals involving NIH scientists, and dealing with Congress do show that research politics can be a helmet sport. (powells.com)
However, following the successful derivation of human embryonic stem cells in 1998, the debate over human cloning largely shifted to the question of whether it is acceptable for scientists to create human embryos only to destroy them. (thenewatlantis.com)
But cloning research continued, and American scientists announced in 2013 that they had for the first time successfully obtained stem cells from cloned human embryos. (thenewatlantis.com)
In Japan, scientists at Kyoto University announced in January that they had successfully produced embryonic stem cells domestically for the first time. (publicintegrity.org)
Umbilical Cord Blood Storage Company Sees Growth Umbilical Cord Stem Cell Storage Resources Arkansas House Votes to Create Umbilical Cord Stem Cell Bank Scientists Claim They Discovered Molecule That Might Help Embryonic Stem Cells Grow US Senate Vote for. (physiciansforlife.org)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)

While Somerville does not seem to disagree with the creation of embryos for in vitro fertilization, she states that embryos are indeed human life that should be respected. (catholicnewsagency.com)
While the Catholic Church has maintained opposition to in vitro fertilization and experimentation on the developing human fetus, what limits should be placed on science and how to enforce them have been debated since culturing humans in labs became possible in the 1970s. (thetablet.org)
Today, this technique continues to form the foundation for research on mammalian embryos, including technologies such as transgenic engineering, embryonic stem cell therapy, human in vitro fertilization, mammalian cloning, and knockout engineering. (avma.org)
… "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
Egg harvesting and Embryonic Stem-cell Research Pose Serious Threat to Women's Health A congressional hearing last Thursday raised awareness on the risks to women's health and fertility by in vitro fertilization (IVF), human cloning, embryonic stem-cell. (physiciansforlife.org)
Apparently distinct mechanisms of de novo lumen formation observed in vitro - in three-dimensional cultures of endothelial and Madin-Darby canine kidney (MDCK) cells - and in vivo - in zebrafish vasculature, Caenorhabditis elegans excretory cells and the Drosophila melanogaster trachea - in fact share many common features. (bvsalud.org)
In this thesis, human glia-to-neuron direct conversion and engineered viral vectors are explored using pre-clinical in vitro and ex vivo models. (lu.se)

Specificity Comments: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. (thermofisher.com)
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. (thermofisher.com)
In this One-on-One, Medscape Editor-in-Chief Eric Topol talked with Dr Church about his many research interests, the promise and controversy of CRISPR gene editing, and how he never gets bored. (medscape.com)
Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)

TORONTO (CNS) - The international scientific body governing stem cell research is abandoning the absolute 14-day limit on culturing human embryos in the laboratory, putting pressure on Canada's law prohibiting the practice. (thetablet.org)

Although the latest scientific work related to cloning has been focused on potential medical applications, much of that research is relevant to the creation of cloned children. (thenewatlantis.com)

The other paper claimed Hwang's team successfully cloned a human embryo to be killed for her stem cells. (lifenews.com)
On the other hand, research involving adult stem cells has not only been around for a long time, it has also been used successfully for decades! (all.org)
Last year, Hwang's team said it successfully cloned a human embryo from embryonic stem cells. (blogspot.com)
However, Korean television station MBC has conducted interviews with an unnamed member of Hwang's research team who says the cells were never cloned successfully. (blogspot.com)

This means that critical medical treatments can be refused patients or removed from them without their consent, live organs can be removed, or, as bioethicist Dr. Richard Frye (Senior Scholar, The Hastings Center) publishes, we have a strong moral obligation to use such non-person human beings ("possible people") in purely experimental destructive research for the greater good of society IN PLACE OF THE HIGHER PRIMATES WHO ARE PERSONS. (lifeissues.net)
Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
A stem cell is a type of cell found throughout the body of all human beings. (all.org)
If you're armed with the facts, you can defend millions of embryonic human beings, and maybe even help celebrities and media figures learn the truth. (all.org)
The New Atlantis is building a culture in which science and technology work for, not on, human beings. (thenewatlantis.com)
Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)
2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)

This study describes for the first time, a differentiation system that does not require co-culture with animal cells or products, thus allowing the production of pathogen-free RPE cells suitable for transplantation into patients. (news-medical.net)
First, we utilized single cell sequencing to dissect the differentiation of stem cells to midbrain dopaminergic neurons. (lu.se)
Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM). (bvsalud.org)
Notch-1, Jagged-1, Jagged-2, and stem cell marker Nanog are expressed in SHED cultured in KGM which may be involved in the differentiation into epithelial-like cells in human dental pulp tissues. (bvsalud.org)
Since the Notch signaling pathway molecules play an important role in differentiation of epithelial cells, it is important to identify the presence of notch signaling molecules in SHED during the process of cell differentiation. (bvsalud.org)
The Notch signaling pathway provides important intercellular signaling mechanisms essential for cell fate specification and it regulates differentiation and proliferation of stem or progenitor cells by para-inducing effects 3-4 . (bvsalud.org)
Notch signaling pathway is also involved in the regulation of epithelial cell differentiation in various tissues 5-6 . (bvsalud.org)
Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)
Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age. (lu.se)

In addition to retinal cells, other stem-cell derivatives are likely to play an important role in the future of regenerative medicine. (news-medical.net)
Advanced Cell Technology is a leading biotechnology company in the emerging field of regenerative medicine. (news-medical.net)

There are differences-so much so that despite the "exact copy" claim, the cloned organism is actually unique genetically. (all.org)
XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
… "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)

An Australian ban on therapeutic cloning was lifted in December 2006 after a long debate in Federal parliament. (bioedge.org)
During a recent appearance on the Oprah Winfrey show, the popular cardiovascular surgeon and television personality, Dr. Mehmet Oz, announced to a stunned audience that due to advances in adult stem cell technology, the debate over embryonic stem cells "is dead. (womenofgrace.com)
Reproductive cloning in humans and therapeutic cloning in primates: is the ethical debate catching up with the recent scientific advances? (bmj.com)
The finding that adult cells can fuse with ES cells is therefore irrelevant to the debate, and the fact that it was used in an attempt to discredit adult stem cells is itself revealing, particularly in view of other recent findings on ES cells. (i-sis.org.uk)
In the ongoing debate over embryonic stem cells some have argued that the cells have not demonstrated their potential value in medicine. (news-medical.net)
Regardless of how well read you are on the embryonic stem cell debate, I think you will find Brahm's treatment to be accessible and informative. (alexchediak.com)

For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
There are those in the government and scientific community who say more money must be spent on human embryonic stem cell research because it holds the most promise for helping people with conditions such as Alzheimer's disease. (all.org)
Alzheimer's researcher Ned Potter said, however, that human embryonic stem cell research would not help the Alzheimer's patient at all. (all.org)
In Alzheimer's, it is the degeneration of the nerve cells that cause the problem because they lose their ability to connect with each other. (all.org)

If research involving human embryonic stem cells (ESCs) is to achieve its potential for creating breakthrough medical therapies, additional new cell lines should be created, and therapeutic cloning--or somatic cell nuclear transfer (SCNT)--should be employed, according to an expert panel of the National Academy of Sciences. (the-scientist.com)
These progenitors which are derived from either embryonic stem cells (ESCs) or healthy induced pluripotent stem cells (iPSCs) express wild-type levels of a-syn, thus making them equally susceptible to developing Lewy bodies over time. (lu.se)

A new controversy is brewing over government backing of Ebola vaccines that are using aborted fetal cell lines even though vaccines developed from moral alternatives are just as effective. (womenofgrace.com)
Transplantations of fetal tissue in the 1980s and 1990s provided proof-of-concept for the potential of cell replacement therapy for PD and some patients benefitted greatly from their transplants. (lu.se)

The first part of the thesis (Paper I, II, III) shows the development and improvement of a hESC-based system of for virus-mediated direct reprogramming of human glial progenitor cells into both induced dopaminergic neurons (iDANs) and GABAergic interneurons. (lu.se)
To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)

It reportedly has access to 7,200 human eggs for its research. (bioedge.org)
Other improvements over the last paper include the reduced use of animal products in laboratory procedures and better evidence that the cell lines matched the patients' cells and did not have a parthenogenetic origin, where unfertilized eggs can divide on their own. (scienceblog.com)
Even if you don't have a religious view of the sanctity of life, you have to ask is there going to be a massive trade in human eggs from poor women to rich countries. (wikiquote.org)
Rep. Mark Souder, Republican chairman of the House of Representatives Government Reform subcommittee on criminal justice and drug policy, said he was disturbed by reports that women in South Korea were paid to donate their eggs for the fraudulent research. (jpost.com)

When we announced the big iPSC breakthrough on November 20th, 2007 we have continued to see more and more promise AND progress with this ethical research. (cbc-network.org)
Keep in mind, this is ethical adult stem cell research, which is in human clinical trials, helping patients NOW. (cbc-network.org)
Blowing past the 14-day limit opens numerous ethical challenges, said Suzanne Scorsone, research director for the Archdiocese of Toronto, who was a commission member in the 1990s. (thetablet.org)
Specifically, two new procedures are being reported in an effort to avoid the ethical offense of killing the embryo when extracting stem cells. (christianliferesources.com)
The director of the lobby group Australians for Ethical Stem Cell Research, David van Gend, criticised the issuing of the licence. (bioedge.org)
In a Science "Policy Forum" related to the team's latest findings, David Magnus and Mildred Cho from Stanford University in Palo Alto, CA discuss international oversight and ethical issues in oocyte donation, including the need to promote realistic expectations of the outcomes of stem cell research. (scienceblog.com)
While ethical issues about (egg) donation should be debated and the process regulated, the scientific conclusions of Dr. Hwang's research remain intact," Schatten said in a statement. (blogspot.com)
The report offers an ethical and policy analysis, articulating what makes cloning morally repugnant and calling for the practice to be definitively prohibited in the United States. (thenewatlantis.com)
Ethical concerns relate to the risk of causing physical and psychological harm, lack of respect for ethical research standards, exploitation of the poor and conflict of interest if financial interests are involved. (who.int)
3 The resolution recognizes the need to respect the freedom of ethical scientific research and to ensure access to the benefits of its application. (who.int)

And the federal policy doesn't prohibit the use of all embryonic stem cells. (breakpoint.org)
Other policy options, such as supposed compromises that would prohibit "reproductive cloning" but permit "therapeutic cloning" by prohibiting not the act of creating a cloned embryo but the act of transferring a cloned embryo to a woman's uterus, would inherently mandate the wide-scale destruction of human embryos. (thenewatlantis.com)

They found that the spontaneous mutation frequency in ES cells is 100-fold lower than that in mouse embryonic fibroblasts (a somatic cell line), which is similar to adult cells in vivo . (i-sis.org.uk)
2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)
Human CMV grows only in human cells and replicates best in human fibroblasts. (medscape.com)

According to MBC, the scientist "maintains that Hwang's team fabricated data because in reality it failed to clone a somatic cell and instead used a frozen embryo from the hospital to make stem cells. (blogspot.com)

While he was NIH director, controversy over embryo research was unremitting. (powells.com)
Among the largest Asian countries, Japan was an early pioneer in regulating human embryo research, pledging international cooperation on the issue following pronouncements on the subject at a June 1997 meeting of the Group of Eight in Denver, Colorado. (publicintegrity.org)

In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)
Our facilities provide the opportunity to study molecules, cells, organs and entire organisms. (lu.se)

Right now, the hottest area in stem cell biology is that of induced pluripotent stem cells, or iPS cells, which have the ability to develop into several different tissue types. (cbc-network.org)
If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)
Obtaining stem cells from fatty tissue, bone marrow, or the umbilical cord after the birth of a baby, on the other hand, may be done ethically. (all.org)
Based on the physical characteristics of the sample, biobanks can be classified into several categories, such as tissue biobanks, cell biology banks, and blood biobanks. (technavio.com)
Two reports appeared as advance online publications in the top British journal Nature , accompanied by a news report that begins, "The hyped ability of adult stem cells to sprout replacement tissue types is being called into question. (i-sis.org.uk)
Adult Stem Cells Taken from Human Fat Tissue Used to Treat Heart Failure Sweden Company Wants To Start First Stem Cell Research Factory Leading Scientist Charges Colleagues With "Misleading" Public British Stem Cell Researcher: Benefits of. (physiciansforlife.org)
A lumen can be generated by tissue that enwraps a pre-existing extracellular space or it can arise de novo either between cells or within a single cell in a position where there was no space previously. (bvsalud.org)
However, post-mortem analysis of transplanted tissue revealed accumulation of pathological Lewy bodies in a small subset of transplanted cells over time, revealing a host-to-graft disease propagation. (lu.se)
Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. (lu.se)

To refer to an already existing human embryo, who science has documented for over a hundred years is a new already living human being, as "a child to be" or "future child" is ridiculous on its face, and oddly reminiscent of the draconian government public policies of recent major bioethics British eugenicist and Oxford don R. M. Hare (mentor of Peter Singer). (lifeissues.net)

This was confirmed by examining the cells chromosomes and identifying the distinctive chromosomes from both mouse lines. (i-sis.org.uk)
The hybrid cells carrying four sets of chromosomes (instead of the usual two) behaved as stem cells when injected into mouse embryos. (i-sis.org.uk)
The fused cells were found to have 4 to six sets of chromosomes by DNA analysis, and they behaved as ES cells when tested. (i-sis.org.uk)

Margaret Somerville, founding director of the McGill Centre for Medicine, Ethics and Law at McGill University in Montreal, makes her case from a purely academic and secular perspective in a comment published in the National Post last week, called "The ethics of stem cells. (catholicnewsagency.com)
Research ethics and lessons from Hwanggate: what can we learn from the Korean cloning fraud? (bmj.com)
1 ). Bioethics is multidisciplinary and pluralistically draws on evant bioethics-related issues such as ethics during disasters science, life technology, laws, traditions, and human values and emergencies. (who.int)
In recent decades, great strides have been made in biomedi- cal ethics, especially in the fields of education, research and legislation. (who.int)
Great Iranian Muslim scholars netics, stem cell research, and organ trans- laid huge emphasis on teaching and practis- plantation are some of the medical issues ing ethics. (who.int)

Stem cell research has limitless potential to help cure devastating diseases, from Parkinson's to diabetes and even many forms of cancer," said Governor Rod Blagojevich. (bioedge.org)
2. Omitting that the diseases everyone is talking about curing (diabetes, Parkinson's, paralysis) have already been treated with adult stem cells. (alexchediak.com)
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? (lu.se)
Based on discussions held by a global collaborative initiative on translation of stem cell therapy in Parkinson's disease, we have identified a set of key questions that we believe should be addressed ahead of every clinical stem cell-based transplantation trial in this disorder. (lu.se)
In this article, we first provide a short history of cell therapy in Parkinson's disease and briefly describe the current state-of-art regarding human stem cell-derived dopamine neurons for use in any patient trial. (lu.se)
With this background information as a foundation, we then discuss each of the key questions in relation to the upcoming therapeutic trial and critically assess if the time is ripe for clinical translation of parthenogenetic stem cell technology in Parkinson's disease. (lu.se)
Stem cell-based therapies for Parkinson's dis- ogy company International Stem Cell Corporation ease (PD) are rapidly moving towards clinical trials. (lu.se)

Human embryos do not possess "human status": "In fact, the only result we can see of a law commanding doctors to treat the microscopic embryo as a 'patient' is a not-so-subtle conferring of 'human status' on embryos, which the Council has allegedly disavowed because of disagreement over the moral status of embryos. (lifeissues.net)
Not only would cloning-to-produce-children be a dangerous experimental procedure, one that cannot be consented to by its subjects (the children created by it), it is also a profound distortion of the moral meaning of human procreation. (thenewatlantis.com)

An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. (thermofisher.com)
Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. (lu.se)

But, although the mutation frequency of genes was much lower in ES cells, mutant ES cells accumulated with time in culture. (i-sis.org.uk)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)
Below is a non-exhaustive list of in-house infrastructures that are categorized into three overarching themes: bio-imaging, proteins, genes & cells and other resources. (lu.se)
In addition to infrastructures for bioimaging, protein and genes & cells, we also provide other resources e.g., databases, networks and specialized labs. (lu.se)

These cell lines will enable the study of human disease in cells in the laboratory. (scienceblog.com)
In laboratory culture, these cell lines displayed signs of immunological compatibility with the patients' cells, Science authors reported. (scienceblog.com)

On May 26, the International Society for Stem Cell Research said it was relaxing the 14-day rule, which prohibited experiments on human embryos past 14 days of development in the lab. (thetablet.org)
It is unspeakable that we should continue this project of creating living human embryos with the sole purpose of destroying them when the compelling justification for such experiments has gone,' Dr van Gend said. (bioedge.org)
Human cloning is a reality, with human cloning experiments now being conducted-not by fictional wild-eyed rebels, but by credentialed experts working in some of the world's most respected institutions, some of which are publicly funded with tax dollars. (all.org)
US lawmakers debated embryonic stem cell research Tuesday in the aftermath of fabricated experiments in South Korea. (jpost.com)
After speaking on a 3 Aug 2005 radio show, he drew criticism for his extreme opinion that embryonic stem cell compares with Nazi deathcamp experiments. (todayinsci.com)
Neither report cited a paper published last year in the journal Blood [4], where a group from the Stem Cell Institute, Department of Medicine, and Cancer Center, University of Minnesota Medical School, Minneapolis, reported the most comprehensive experiments proving that a single adult stem cell can differentiate into all cell types in culture. (i-sis.org.uk)

The NAS recommendations are likely to further fuel public policy debates over the future of human ESC research. (the-scientist.com)
The Threat of Human Cloning begins by laying out the scientific and policy background of the cloning debates. (thenewatlantis.com)
The present report gives an overview of the terms and methods used in cloning and summarizes the debates in the General Assembly. (who.int)

A well-respected medical ethicist from one of Canada's leading universities says Canada must not legalize embryonic cloning for any purpose, including therapeutic purposes. (catholicnewsagency.com)

After being inserted into the egg, the adult cell nucleus is reprogrammed by the host cell. (eurostemcell.org)

Can a person be considered cultured today with only slight knowledge of fields such as molecular biology, artificial intelligence, chaos theory, fractals, biodiversity, nanotechnology or the human genome? (edge.org)
These cells expressed RPE-specific molecular markers and were capable of phagocytosis, an important RPE function. (news-medical.net)
Differentiomics could also be a valuable predictive tool for quality assessment of other ES cell derivatives based on their molecular signature. (news-medical.net)
Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)

Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)

Thanks to our world-class research infrastructure, Lund University is well equipped to help lead the way towards future scientific breakthroughs. (lu.se)

Some in vivo transplantation studies have reported robust (35-50%) levels of transdifferentiation, which makes it unlikely that the results are due to cell fusion events. (i-sis.org.uk)

He added that treatments for dreaded diseases "could be right at our fingertips" if we lifted "the stem cell ban. (breakpoint.org)
The papers claimed the team created patient specific embryonic stem cells that would overcome the problems of a patient's immune system rejecting the cells in treatments. (lifenews.com)
Yet, human embryonic stem cell research has thus far been unsuccessful in the quest to develop any therapeutic treatments. (all.org)
Research institutions are exploring in-depth ways to develop personalized treatments using biological samples. (technavio.com)
Biobank equipment plays an important role in maintaining sample quality and integrity for precision medicine research and personalized treatments. (technavio.com)
The developments utilizing adult stem cells, however, have been truly amazing with medical treatments (not mere potential or grand promises) already helping thousands of people. (blogspot.com)
Cloning-for-biomedical-research also endangers the health and safety of the women called on to undergo dangerous hormone treatments to serve as egg donors. (thenewatlantis.com)

He said no human clinical trials or therapeutic applications using human embryonic stem cells currently exist. (jpost.com)
Today, clinical trials using stem cell-derived dopaminergic progenitors have commenced. (lu.se)

Frozen storage of human ova, embryonic stem-cell research, surrogate motherhood, and the question of human cloning make up just part of the growing list of medically acceptable but morally objectionable techniques and practices. (catholicculture.org)

Japan subsequently enacted legislation in late 2000 criminalizing the cloning of human embryos for reproductive purposes. (publicintegrity.org)

This method is called "somatic cell nuclear transfer" or SCNT. (scienceblog.com)

For example, the stem cells can differentiate into cells that display characteristics of skin and retina cells, muscle cell bundles, bone matrix cells and cells of the gastrointestinal and respiratory lining. (scienceblog.com)
Besides use in the aging retina, human embryonic stem cells have now demonstrated the potential to change the face of several age-related degenerative diseases, perhaps one day allowing physicians to prescribe young cells they way they dispense pills today. (news-medical.net)

Currently, the procedure for isolating non-reproductive cells for the nuclear transfer method involves animal enzymes and serum. (scienceblog.com)
The single cell line generated in the 2004 Science paper resulted from nuclear transfer in which the oocyte and non-reproductive ("somatic") cell came from the same healthy female. (scienceblog.com)
The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. (scienceblog.com)
More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)

The following product was used in this experiment: SOX2 (Embryonic Stem Cell Marker) Recombinant Rabbit Monoclonal Antibody (SOX2/4267R) from Thermo Fisher Scientific, catalog # 6657-RBM7-P1. (thermofisher.com)
However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker. (thermofisher.com)
RNA was reverse-transcribed to obtain the cDNA and then proceeded with PCR using specific primers for the Notch signaling pathway molecules (Notch1, Jagged-1, Jagged-2 and, Hes1) as well as stem cell marker (Nanog). (bvsalud.org)

Kass calls it "cruel to suggest that stem-cell-based therapies are 'at our fingertips. (breakpoint.org)
The data presented in this thesis may serve as valuable resources to help optimize future cell replacement therapies for patients suffering from PD. (lu.se)
It's adequately funded, but our main work is on finding therapies for human diseases. (medscape.com)

Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
Cloning-to-produce-children could also be used to attempt to control the physical and even psychological traits of children, extending the eugenic logic of those who would use reproductive biotechnology to have the perfect child. (thenewatlantis.com)
China has reportedly been increasing its funding for cloning and other biotechnology research efforts. (publicintegrity.org)

The U.S. Food and Drug Administration (FDA) has approved the world's first human clinical trial of a therapy involving embryonic stem cells, a move that has been condemned by the Vatican as "unacceptable. (womenofgrace.com)
There are more than 70 diseases or conditions-including leukemia, immune system and other blood disorders, cancers, and autoimmune diseases-that respond well when adult stem cell therapy is used. (all.org)
Because of this local degeneration of a relatively small population of dopaminergic neurons in the midbrain, PD has been considered an especially interesting candidate for cell-replacement therapy. (lu.se)
The overall aim of this thesis has been to assess the potential of autologous grafting in cell replacement therapy for PD. (lu.se)
Next, in order to study the potential of autologous cell replacement therapy we transplanted progenitors derived from a PD patient into a pre-clinical rat model. (lu.se)

Human embryonic stem cell research began in the 1990s. (thetablet.org)

In the name of science and health, human life is destroyed at its very inception and "limited" cloning is used to produce usable cells that can be manipulated and harvested to aid the living. (lifenews.com)
When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
It involves extracting a cell from an embryo and then stimulating that cell to produce stem cells. (christianliferesources.com)
More than 90% of cloning attempts fail to produce viable offspring. (wikiquote.org)
They also have the capability to produce other types of specialized cells, such as brain cells, muscle cells, and lung cells, to name but a few. (all.org)
This kind of cloning is today being performed at several scientific labs in the United States, despite the availability of alternative techniques that produce cells of nearly the same scientific and medical value but that require neither the creation nor destruction of human embryos. (thenewatlantis.com)
In sexual reproduction, clones are created when a fertilized egg splits to produce identical (monozygous) twins with identical genomes. (who.int)
Several academic and industry efforts are well under owned subsidiary Cyto Therapeutics, it had received way to produce dopaminergic neurons from stem approval by the Australian government to conduct a cells under conditions compliant with use in patients. (lu.se)

This report - written to be understood by non-specialists, including policymakers and the general public - explains the history of cloning as well as recent developments. (thenewatlantis.com)

Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)

The privately-funded experiment, which took place at Seoul National University under the guidance of Korean Hwang Woo-suk and American Jose Cibelli, was only the latest in a group of announcements from research institutions in Asia in the last few years, and demonstrates that cloning research is becoming "globalized" like any other commodity. (publicintegrity.org)

Anatomy34

Organisms7

Diseases2

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Psychiatry and Psychology1

Phenomena and Processes34

Disciplines and Occupations5

Technology, Industry, Agriculture1

Humanities1

Information Science2

Opponents of embryonic stem-cel3

Blastocyst10

Embryos for research3

Dolly10

Researchers19

Abortion7

Somatic cells2

Genetic18

Dignity18

Scientists21

Vitro7

Gene4

Culturing human embryos1

Creation of cloned1

Successfully4

Beings10

Differentiation11

Regenerative Medicine2

Organism3

Debate6

Alzheimer's4

ESCs2

Fetal2

Progenitor cells2

Eggs4

Ethical10

Prohibit2

Fibroblasts3

Hwang's1

Embryo research2

Organisms4

Tissue9

Existing human embryo1

Chromosomes3

Ethics5

Parkinson's7

Moral2

Pluripotent state2

Genes5

Laboratory2

Experiments6

Debates3

Therapeutic purposes1

Adult cell1

Molecular4

Biology1

Lund University1

Transplantation1

Treatments7

Clinical trials2

Surrogate1

Reproductive purposes1

SCNT1

Retina2

Nuclear4

Marker3

Therapies3

Biotechnology3

Therapy5

1990s1

Produce8

Developments1

Genetically identical3

Demonstrates1