Research clone. Medical search. Frequent questions

Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
Figure 1: Dog cloned by somatic-cell nuclear transfer. (nature.com)
Before the announcement in February 1997 of the cloning of a sheep by somatic cell nuclear transfer, existing legislation in a number of countries already precluded human cloning for reproductive purposes, sometimes implicitly. (who.int)

NEW YORK, September 21, 2003 - New research from Memorial Sloan Kettering Cancer Center (MSKCC), Cornell University, and The University of Connecticut describes a novel way of producing therapeutic nerve cells that can cure mice with Parkinson's-like disease. (mskcc.org)
Is so-called 'therapeutic' human cloning really necessary? (biosafety-info.net)
The heated debate in our society over reproductive cloning, as well as therapeutic cloning to obtain embryonic stem cells, has been fueled by misconceptions and hyperbole on both sides. (flfamily.org)
In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
Therapeutic cloning, which creates embryonic stem cells . (medlineplus.gov)
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. (sigmaaldrich.com)
Many research and therapeutic applications are currently limited by the low efficiency of precise HDR-based editing. (nature.com)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)

When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
In most countries, it is illegal to attempt reproductive cloning in humans. (eurostemcell.org)
2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
These preparatory interregional and interdisciplinary meetings focused on the following areas: cloning and human reproductive health, biologicals, organ transplantation, research, and medical genetics. (who.int)
The main objection to the use of human cloning for reproductive purposes is that it would be contrary to human dignity as it would violate the uniqueness and indeterminateness of the human being. (who.int)
Some, however, consider that reproductive cloning could be acceptable in certain cases, such as otherwise untreatable infertility, or to avoid inherited genetic diseases. (who.int)
In terms of existing ethical guidelines for biomedical research involving human subjects, human cloning for reproductive purposes raises concerns about risk in relation to benefit, informed consent, and accountability. (who.int)
Human cloning for reproductive purposes is seen as having the potential to disrupt intergenerational relations and family structures, with major psychological, social and legal consequences for the individuals and communities concerned. (who.int)
Some also perceive reproductive cloning as a high-technology intervention of little relevance to the health needs of the vast majority of the world's population. (who.int)
Since then, many countries have adopted government decrees or introduced legislation to impose an explicit ban on human cloning for reproductive purposes. (who.int)

Twenty years ago today, the world's first clone made from the cells of an adult mammal made her public debut. (pewresearch.org)
To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
The world's first human clone of an adult has now been made, by an American biotechnology company in Massachusetts, Advanced Cell Technology. (globalchange.com)
Roy is the lead author of the widely used NiCad clone detection system and co-editor of the world's first book on code clone analysis. (usask.ca)
The US is the world's leader in research funding, and it plans to continue making advances in stem-cell research even as the United States remains behind in other fields such as cancer treatments and embryonic stem cell research, which are also important for human health, some medical ethicists say. (supermercadosfrigo.com.uy)

Dolly, a Finn Dorset sheep, was introduced to the public in 1997 after scientists at the Roslin Institute at the University of Edinburgh in Scotland implanted the cell nucleus from a sheep into an egg that was subsequently fertilized to create a clone. (pewresearch.org)
1 No one has ever cloned a human being , though scientists have cloned animals other than Dolly , including dogs, pigs, cows, horses and cats. (pewresearch.org)
Still, a majority of adults (60%) say cloning animals like Dolly is morally wrong, compared with 34% who say it's morally acceptable. (pewresearch.org)
Remember in 1996, Dolly the sheep was cloned as the first known animal to survive a cloning process. (truthseekerforum.com)
Let's wind back the clock: these scientists had already carried out successful human nuclear transfer into an unfertilised egg before Dolly the sheep clone had been made. (globalchange.com)
But even they omitted to tell us anything until Dolly was seven months old, well over a year after the cloning technique was successfully carried out and a good two to three years perhaps after they began their secretive work. (globalchange.com)
The most famous clone was a Scottish sheep named Dolly. (medlineplus.gov)

Catholic teaching on difficult issues, like stem cell research and cloning, must be understood in order to recognize and respect all human life. (catholicscomehome.org)

Molecular Cloning: A Laboratory Manual, (3rd ed. (neb.com)
Molecular cloning of DNA was used to investigate the expression of type b capsule and its association with H. influenzae virulence. (jci.org)
Despite improvements in the CRISPR molecular toolbox, identifying and purifying properly edited clones remains slow, laborious, and low-yield. (nature.com)
It is ranging from cloning and molecular development to production and characterization. (lu.se)

No persuasive reason exist for cloning save for genetic determinists who believe an organism is nothing more than the sum total of its genetic make-up and that it is their right to exploit cloned human embryos for spare body parts. (biosafety-info.net)
Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)
A clone is an organism that is a genetic copy of an existing one. (who.int)

Part of the reason is that cloning can introduce profound genetic errors , which can result in early and painful death. (pewresearch.org)
In 2001, Lorenz Studer, MD , Head of the Stem Cell and Tumor Biology Laboratory at MSKCC, and his colleagues at Rockefeller University published research in which they generated unlimited numbers of genetically matched dopamine nerve cells using cloned stem cells whose genetic material originated from the mouse's own tail. (mskcc.org)
After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
The copied material, which has the same genetic makeup as the original, is referred to as a clone. (medlineplus.gov)
5. Most countries in the African Region have no specific regulations and policies governing genetic manipulations for assisted conception, treatment and research. (who.int)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)

Through cloning of functional p53-binding sites (p53-tagged sites) from the human genome, we isolated a novel gene inducible by wild-type p53. (aacrjournals.org)
The entire genome of human papilloma virus type 1a was cloned in Escherichia coli using the plasmid pBR322 as vector. (pasteur.fr)
Viral DNA isolated from a single wart was partially methylated at only one out of the four HpaII sites, d(C-C-G-G). Recognition sites for Bg/I, Bg/II, PstI and PvuII restriction endonucleases were located on the cloned genome. (pasteur.fr)
When genome editing induces a phenotypic alteration that is detectable by fluorescence (i.e., cell-surface expression of a target that can be non-lethally assessed with fluorescently labeled antibody), FACS provides a method of enriching edited cells 9 , narrowing the number of clones to propagate and analyze. (nature.com)
The team set out to learn which parts of the genome tend to be mutated in clones, which mutations are most harmful, and how clones arise and expand their numbers. (innovitaresearch.com)

Paul Wagle, M.A., discusses his experience with a life-saving adult stem cell treatment, and the importance of promoting ethical approaches to medical research. (flfamily.org)
For decades, proponents of destructive embryo research have given at least lip service recognition to the serious ethical concerns inherent to such research. (flfamily.org)
Cracking Cloning Nuclear transfer research encompasses some of the most compelling biological and ethical puzzles of our time. (the-scientist.com)
The Commission has also requested that the European Group of Ethics provide an updated opinion on the ethical aspects of cloning techniques, paying particular attention to the health risks for cloned farm animals and the possible effects on biodiversity. (pigprogress.net)
Ethical concerns relate to the risk of causing physical and psychological harm, lack of respect for ethical research standards, exploitation of the poor and conflict of interest if financial interests are involved. (who.int)
3 The resolution recognizes the need to respect the freedom of ethical scientific research and to ensure access to the benefits of its application. (who.int)
It reports on implementation of resolution WHA50.37 concerning ethical, scientific and social implications of cloning in human health. (who.int)
Resolution WHA50.37 requested the Director-General to clarify the potential applications of cloning procedures in human health and their ethical, scientific and social implications. (who.int)

Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport. (jci.org)
We have recently cloned, sequenced, and characterized a rat kidney cDNA (D2) that stimulates cystine as well as dibasic and neutral amino acid transport. (jci.org)
In order to evaluate the role of this protein in human inherited diseases such as cystinuria, we have isolated a human D2 clone (D2H) by low stringency screening of a human kidney cDNA library using the radiolabeled D2 insert as a probe. (jci.org)
In this article, we report cloning of the rat apelin receptor cDNA. (nih.gov)

They took a cell from Dr Jose Cibelli, a research scientist and combined it with a cows egg from which the genes had already been removed. (globalchange.com)

Using TCR alpha and beta repertoire sequencing for T-cell subsets, as well as single-cell RNAseq and TCRseq, we track the concentrations and phenotypes of individual T-cell clones in response to primary and secondary yellow fever immunization - the model for acute infection in humans - showing their large diversity. (elifesciences.org)
The resulting diverse naïve repertoire contains T-cell clones that recognize epitopes of yet unseen pathogens, and can participate in the immune response to infection or vaccination. (elifesciences.org)
Selection of edited cell clones currently relies on limiting dilution or fluorescence-activated cell sorting (FACS)-based single-cell sorting to isolate single cells. (nature.com)

Hwang became a national hero in South Korea after he claimed to have cloned the first human stem cell line in 2004, and stunned medical experts in 2005, claiming to have created 11 patient-specific human stem cell lines. (newscientist.com)
Dolly's debut set off a firestorm about both the practical value and ethics of cloning, including the possibility of human cloning. (pewresearch.org)
Currently, more than 40 countries - including the UK, France, Germany and Japan - formally ban human cloning. (pewresearch.org)
At the same time, labs in a variety of countries have successfully cloned human embryos for the purpose of producing stem cells that can be used in medical therapies. (pewresearch.org)
2 Eight-in-ten American adults (81%) say cloning a human being is not morally acceptable, according to a May 2016 Gallup poll . (pewresearch.org)
There has been overwhelming opposition to human cloning since 2001. (pewresearch.org)
In a 2010 Pew Research Center survey , 48% of adults said that a human being would definitely or probably be cloned by 2050, compared with 49% who said such an event would not happen. (pewresearch.org)
We need to separate the facts from the popular fictions about human cloning. (flfamily.org)
Our products are intended for in-vitro use only for manufacturing and research and are not suitable for human or animal use. (innov-research.com)
Cow / human clone hybrid - cow and human mixed together. (globalchange.com)
What is Human Cloning? (globalchange.com)
Technically 1% of the human clone genes would have belonged to the cow - the mitochondria genes. (globalchange.com)
Judging by the successful growth of the combined human-cow clone creation it appears that cow mitochondria may well be compatible with human embryonic development. (globalchange.com)
However the biggest piece of news is not what they did in human cloning - sensational enough - but the fact that they kept cloning secret for three years after doing it, and presumably they were trying to do it at least a couple of years before that. (globalchange.com)
The lesson is this: today's headlines on human cloning tell us history. (globalchange.com)
Elsewhere on this site I describe my own conversations with a British scientist in the 1980s who was attempting then to clone human embryos - with some success. (globalchange.com)
In these human-cow clones one imagines every court in the world would agree that the child born would be capable of being prosecuted for murder, even though it would technically be 1% cow. (globalchange.com)
Human cloning : Will he ever be able to make himself a new body? (globalchange.com)
In the face of grave concerns about human rights and the use of biomedical research money for illicit purposes, the Chinese government should immediately 클럽 에이 카지노 withdraw its proposed $75 billion investment to advance biomedical research and to accelerate the country's successful advancement in tissue engineering,» Nelson said. (supermercadosfrigo.com.uy)
Cloning is a way to provide better treatment to the poorest Chinese citizens by enabling better medical care and potential 바카라 게임 방법 ly reducing the cost of biomedical research,» said John Delgambo, director of the Center for Gene Therapy and Human Genetics at New York University. (supermercadosfrigo.com.uy)
WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
Several international health-related professional associations and religious bodies have issued statements calling for the careful monitoring and regulation of scientific developments in the field of cloning and human genetics. (who.int)
They emphasize the need to promote the teaching of ethics in medical education and to establish effective measures to protect developing countries from the risk of unregulated expatriate research involving human subjects. (who.int)

Cloning of chromosomal DNA from Haemophilus influenzae. (jci.org)

Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
Scientists have found a way to successfully clone American elm trees that have survived repeated epidemics of their biggest killer -- Dutch elm disease. (sciencedaily.com)
The subject of cloning animals and their offspring is set to go under the microscope in the coming weeks, after the European Commission announced today that it had asked scientists to assess the risks involved. (pigprogress.net)
U.S. officials said Chinese investments in biomedical research could generate $25 billion to $50 billion in revenue, and that the money would be used to support Chinese scientists who are seeking new areas of research, or to develop countries where new and innovativ 온라인 카지노 추천 e biomedical technologies are available. (supermercadosfrigo.com.uy)

Below you can see some examples of the infrastructure for research on genes and cells, available for researchers at Lund University. (lu.se)

P. aeruginosa isolates referred to the ARSP, epidemic clone. (who.int)

A year ago, when the World Bank president, Jim Yong Kim, announced his ambitious plan to push China to put billions of dollars into scientific cloning, many were skeptical he would succeed. (supermercadosfrigo.com.uy)

4 The public is divided about the prospect of using cloning to bring back to life species of animals that are currently extinct , such as the carrier pigeon or even the woolly mammoth. (pewresearch.org)
In a 2013 Pew Research Center poll , half of all adults surveyed (50%) said that by 2050 researchers will be able to use cloning to bring back extinct species, with 48% predicting such a development won't occur. (pewresearch.org)

Clones (We're All)" is a 1980 single by American rock singer Alice Cooper taken from his fifth solo studio album Flush the Fashion (1980). (wikipedia.org)

3 Americans are divided as to whether humans will be cloned in the near future. (pewresearch.org)
5 Fewer Americans are concerned with cloning animals than with the prospect of cloning humans , according to the same 2016 Gallup survey . (pewresearch.org)

Roy was recognized for his research into the detection and management of software clones: duplicated fragments of code in software systems that result in increased errors and maintenance costs. (usask.ca)
Subsequently a stable CHO cell line expressing the receptor fused at its C-terminal part with the enhanced green fluorescent protein (EGFP) was established, allowing to verify its cell surface distribution and to determine the affinity of various apelin and angiotensin fragments on the cloned receptor. (nih.gov)

Fetal Tissue Research: Antiquated and Unethical? (flfamily.org)
The accuracy of any impression material, including Thermo Clone VPS, can be increased with the use of Ultradent's Tissue Management System . (ultradent.com)
Looking for new techniques to clone and produce resistant trees through micropropagation, the Guelph researchers selected tissue samples from survivors in Ontario, including a century-old elm tree growing on the U of G campus. (sciencedaily.com)
But, recently, Kim said China would invest $50 billion in cloning and $75 billion in tissue engineering, leading many analysts to put more faith in Kim's plans. (supermercadosfrigo.com.uy)
Cloning, tissue distribution and methylation analyses of Lhx9 in Chinese tongue sole (Cynoglossus semilaevis). (bvsalud.org)
Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. (lu.se)

Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)

The increased level of sensitivity allowed the team to find clones in more than 8,000 participants, many of whom had acquired similar mutations. (innovitaresearch.com)

The committee said Hwang had forced two of his junior researchers to give eggs for his stem cell research, contrary to his earlier denials of forcing any of his staff to contribute eggs. (newscientist.com)
Roy is widely credited with helping revitalize interest in software clones, which have seen increased attention from researchers around the world since his first work in the field. (usask.ca)
USask researchers received two additional awards at the 17th International Workshop on Software Clones. (usask.ca)
The researchers were then able to figure out the specific ways that the inherited variants made people vulnerable to developing clones. (innovitaresearch.com)

At the end of the 60 Minutes episode, the doctor /scientist who was responsible for the cloning procedure spoke about the past, present, and future of cloning. (truthseekerforum.com)
This research has the potential to bring back the beloved American elm population to North America," said Prof. Praveen Saxena, a plant scientist who worked on the project with Professor Alan Sullivan. (sciencedaily.com)
A University of Saskatchewan (USask) computer scientist has earned another honour for his influential work in the rising field of software clone research. (usask.ca)
He is a previous recipient of the College of Arts and Science's New Scientist Research Award, USask's New Researcher Award and the CS-Can/Info-Can Outstanding Young Computer Science Researcher Award. (usask.ca)

The European Food Safety Authority (EFSA) has been asked to assess the implications of cloning for food safety, animal health, animal welfare and the environment, in a bid to help the Commission determine how to deal with such animals and their by-products in the years to come. (pigprogress.net)

1. Cloning is an umbrella term traditionally used to describe different processes for duplicating biological material. (who.int)

But there are still concerns about the ethics of putting money into such research, he added. (supermercadosfrigo.com.uy)

The Ph.D.™ Peptide Display Cloning System contains M13KE vector, the parent vector of NEB's Ph.D. libraries. (neb.com)
Because this is a phage, rather than a phagemid vector, all 5 copies of pIII on the surface of each virion will be fused to the cloned peptide. (neb.com)

This material is sold for in-vitro use only for manufacturing and research. (innov-research.com)
The breakthrough is the first known use of in vitro culture technology to clone buds of mature American elm trees. (sciencedaily.com)
Six parasites ont montré une résistance in vitro au stibogluconate de sodium en utilisant le test de détection des amastigotes dans les macrophages J774 murins. (who.int)

We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
Support Research grants are competed for in order to afford frontline genomic methods and expert data handling. (lu.se)

Clonal hematopoiesis is increasingly appreciated to be an important biomarker of risk for future illness, but we haven't known what brings it about," said the study's co-senior author, Steven McCarroll , the Dorothy and Milton Flier Professor of Biomedical Science and Genetics at HMS and director of genetics at the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard. (innovitaresearch.com)

Just 13% of adults in 2016 say cloning is morally acceptable. (pewresearch.org)
In 2016, China will invest nearly $100 billion in biomedical research - an amount equivalent to the entire annual research budget of the NIH,» said Lee. (supermercadosfrigo.com.uy)

So 21 years ago, it started and now we can clone fully functional Super Horses, which Adolfo has used to win several Polo Championships. (truthseekerforum.com)

Disgraced cloning expert Woo-Suk Hwang has admitted making donations to politicians using funds donated for his research, said South Korean state auditors on Monday. (newscientist.com)
They said that the information would be passed on to prosecutors who are already probing Hwang for possible fraud in connection with his research funding. (newscientist.com)
The Board of Audit and Inspection (BAI) said in a report that Hwang had failed to account for 6.2 billion won ($6.4 million) in donations for his research - one billion won in state funds and 5.2 billion won in private donations. (newscientist.com)

A 4.4-kb EcoRI fragment, common to both DNA clones, was used to characterize clinical isolates representing all six encapsulated serotypes as well as several capsule-deficient H. influenzae by Southern hybridization analysis. (jci.org)
The resistant isolates showed different restriction profiles when the amplified kDNA PCR products were digested with ALU1 restriction enzyme, indicating that resistance was mediated by different parasite clones. (who.int)

So China's future biomedical research spending may outstrip the NIH funding in the next two decades. (supermercadosfrigo.com.uy)

But his fall from grace came swiftly at the end of 2005 and has been gathering momentum since the beginning of 2006 when a scientific verification panel found he had created no embryonic stem cells of any kind and that his research data was fabricated . (newscientist.com)
The work, which will be published in the October issue of Nature Biotechnology (available online September 21), provides the first evidence that cloned cells can cure disease in an animal model. (mskcc.org)
CLI's Vice President and Research Director, Dr. David Prentice, recently joined Molly Smith, host of From the Median, to explain the science, history, and politics of stem cells. (flfamily.org)
Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
a , Snuppy, the first cloned dog, at 67 days after birth (right), with the three-year-old male Afghan hound (left) whose somatic skin cells were used to clone him. (nature.com)
Using this method, single-clone editing efficiencies, including the rate of mono- and bi-allelic indels or precise nucleotide replacements, can be assessed within 10 days from Cas9 ribonucleoprotein introduction in cells. (nature.com)
These genetically dominant blood cells are called clones. (innovitaresearch.com)
To do so, co-first authors Po-Ru Loh , assistant professor of medicine at HMS and Brigham and Women's Hospital, and Giulio Genovese , senior computational biologist in the McCarroll lab, developed a mathematical approach that let them identify clones early on, when they accounted for as little as 1 percent of a person's white blood cells. (innovitaresearch.com)
Previous methods lacked the precision to detect clones unless they had expanded to at least 15 to 20 percent of white blood cells. (innovitaresearch.com)
Hastening the return of the body's white blood cells can reduce the possibility of serious or overwhelming infection associated with stem cell transplantation," Peter Marks, MD, PhD, director of the FDA's Center for Biologics Evaluation and Research, said in an agency press release . (medscape.com)

China would also be pushing in cloning research of more types of animals, such as primates and elephants, said Jochen Steltenberg, director of China's Center for Genomics and Technology. (supermercadosfrigo.com.uy)

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