AntidepressantsSelective serotoninDepressionAntidepressant DrugsTherapeuticTCAsAmoxapineEfficacyAmitriptylineDosageImipramineDifferentialTherapeuticsCentresEffectivenessEffectsInnovationEffectivePotentialProductsJournalClassArticleAntidepressant agentAtypicalSSRICompoundsAntipsychoticNorepinephrinePsychotropic agentsMajor depressiPracticeTreatmentGrantsDrugEnvironmentalTopicsIndividualIntroductionPublicMedical
Antidepressants19
- Newer antidepressants, such as serotonin selective reuptake inhibitors (SSRIs) and venlafaxine, have a wider therapeutic index than the older tricyclic antidepressants. (nih.gov)
- Tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, and gabapentinoids have some evidence for efficacy in central neuropathic pain. (wustl.edu)
- Westenberg, H. G.M. / Anxiety disorders : A review of tricyclic antidepressants and selective serotonin reuptake inhibitors . (tau.ac.il)
- Although serotoninergic agents such as antidepressants have been shown to increase neurogenesis, the effects of MnRN lesions remain to be elucidated. (fapesp.br)
- In the following decades, the monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants were introduced. (beatcfsandfms.org)
- Toxic manifestations of amoxapine overdosage differ significantly from those of other tricyclic antidepressants. (genelabs.com)
- Barbiturates like butabarbital may increase the metabolism of tricyclic antidepressants like amoxipine. (genelabs.com)
- Monitor for decreased therapeutic effects of tricyclic antidepressants if a barbiturate is initiated/dose increased, or increased effects if a barbiturate is discontinued/dose decreased. (genelabs.com)
- Barbiturates such as butalbital may increase the metabolism of tricyclic antidepressants amoxapine. (genelabs.com)
- Selective serotonin reuptake inhibitors versus tricyclic and heterocyclic antidepressants: comparison of drug adherence. (ox.ac.uk)
- SELECTION CRITERIA: Parallel group randomised controlled trials comparing selective serotonin reuptake inhibitors with tricyclic or heterocyclic antidepressants in people with depression. (ox.ac.uk)
- Tricyclic antidepressants and carbamazepine have become the mainstay in the treatment of neuropathic pain. (omeka.net)
- In the absence of research into the efficacy and safety of antidepressants in this group of patients, their off-label prescription is common. (easap.asia)
- The Research on Asia Psychotropic Prescription Pattern on Antidepressants worked collaboratively in 2013 to study the prescription pattern of antidepressants in Asia using a unified research protocol and questionnaire. (easap.asia)
- Tricyclic antidepressants (TCAs) are of proven benefit. (medscape.com)
- As a nootropic , and for cognitive health, St. John's wort is as effective at relieving mild-to-moderate depression as the most commonly prescribed SSRI and TCA (tricyclic) antidepressants. (nootropicsexpert.com)
- This review summarizes the recent research on pharmacotherapy for LLD, updates information on monotherapy using recommended antidepressants, and discusses the clinical features and diagnostic criteria for LLD. (jkma.org)
- Compared to tricyclic antidepressants, these tend to be stronger antihistamines and have less anticholinergic side effects. (drugbank.com)
- Mildly depressed patients were often not good candidates for the tricyclic antidepressants used since the 1950s, or didn't want to risk the potentially severe side-effects of monoamine oxidase inhibitors. (medicaltuesday.net)
Selective serotonin6
- or exp serotonin uptake inhibitors/ or exp serotonin agents/ or (selective serotonin reuptake inhibitors or SSRI? (nationalacademies.org)
- BACKGROUND: Selective serotonin reuptake inhibitors are thought to have better discontinuation rates (i.e. less people dropping out) than tricyclic and heterocyclic antidepressant drugs. (ox.ac.uk)
- OBJECTIVES: To assess the comparative tolerability of selective serotonin reuptake inhibitors and tricyclic/heterocyclic antidepressant drugs. (ox.ac.uk)
- The selective serotonin reuptake inhibitors showed less participants dropping out compared to the tricyclic/heterocyclic group (odds ratio 1.21, 95% confidence interval 1.12 to 1.30). (ox.ac.uk)
- REVIEWER'S CONCLUSIONS: Whilst selective serotonin reuptake inhibitors do appear to show an advantage over tricyclic drugs in terms of total drop-outs, this advantage is relatively modest. (ox.ac.uk)
- This has implications for pharmaco-economic models, some of which may have overestimated the difference of drop-out rates between selective serotonin reuptake inhibitors and tricyclic antdepressants. (ox.ac.uk)
Depression4
- Add-on polytherapy with antidepressant agents was reviewed in 42 inpatients with major depression diagnosed according to the ICD-10 criteria. (elsevierpure.com)
- Clinically, not every patient with major depression can tolerate the adverse side effects induced by an effective dose of a single tricyclic antidepressant. (elsevierpure.com)
- Although single drugs in one or two classes were available for the treatment of depression several decades ago, multiple therapeutic modalities now exist, often with many agents within each class. (beatcfsandfms.org)
- A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. (drugbank.com)
Antidepressant Drugs1
- OR exp anti-anxiety agents/ or exp antipsychotic agents/ OR exp Anticonvulsants/ OR exp Serotonin Reuptake Inhibitors/ or exp Tricyclic Antidepressant Drugs/ or Adrenergic Blocking Drugs/ or exp neuroleptic Drugs/ or exp Anticonvulsive Drugs/) Psychotherapies Set (exp psychotherapy/ or psychotherap$.ti,ab. (nationalacademies.org)
Therapeutic1
- The present study evaluates the possible synergistic antidepressant effect of sub-therapeutic dose of iron co-administered with citalopram or imipramine in female Institute of Cancer Research mice. (bvsalud.org)
TCAs1
Amoxapine3
- Amoxapine, the N -demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). (genelabs.com)
- Amoxapine is a tricyclic antidepressant of the dibenzoxazepine class, chemically distinct from the dibenzodiazepines, dibenzocycloheptenes, and dibenzoxepines. (genelabs.com)
- Atazanavir may increase the effect and toxicity of the tricyclic antidepressant, amoxapine, by decreasing its metabolism. (genelabs.com)
Efficacy3
- More careful assessment of the efficacy of an agent at early and regular intervals, with early revision of the treatment modality if it is not optimal, is an important new guideline that applies not only to somatic treatments, but also to psychotherapeutic approaches and combination psychotherapy-pharmacotherapy when treatment is not proceeding optimally. (beatcfsandfms.org)
- A panel convened in November 2010 found that among the currently recommended analgesic products for arthritis-related pain, fixed-low-dose combination products hold promise for pain control because such products allow lower doses of individual agents resulting in decreased toxicity and acceptable efficacy due to synergy between the individual drugs. (openrheumatologyjournal.com)
- Due to the balance of its efficacy benefit and risk of side effects, as the overall discontinuation rate shown, the acceptability of this agent is not more than placebo. (biomedcentral.com)
Amitriptyline1
- Another example of this is the tricyclic antidepressant, Amitriptyline. (amymyersmd.com)
Dosage2
- Nineteen (67.8%) patients of the polytherapy group were treated with a dosage equivalent to 150 mg/day of tricyclic antidepressant. (elsevierpure.com)
- The tricyclic antidepressant dosage will likely need to be increased during concomitant barbiturate therapy, and reduced upon barbiturate discontinuation. (genelabs.com)
Imipramine2
- So, the effects of MnRN lesion on hippocampal neurogenesis in animals chronically stressed and treated or not with Imipramine (a tricyclic antidepressant) will be investigated too. (fapesp.br)
- Imipramine is a tricyclic antidepressant that possesses anti-inflammatory activity and has been reported to inhibit the progression of highly metastatic non-small cell lung cancer. (bvsalud.org)
Differential1
Therapeutics1
- Like an old dog with new tricks, research is continually finding new ways to use older therapeutics and medications. (amymyersmd.com)
Centres1
- Our interdisciplinary Research Centres are the home of world-class research that brings together expertise from across the University enabling us to provide real-world solutions and opportunities that have an impact on society. (uclan.ac.uk)
Effectiveness1
- Recent research shows its effectiveness in treating cancer, inflammation, bacterial and viral diseases. (nootropicsexpert.com)
Effects1
- The study concluded that ketamine benefits the increase of prefrontal serotonin release, rapidly eliciting antidepressive effects. (amymyersmd.com)
Innovation1
- We have a strong reputation for applied business research, entrepreneurship and innovation, offering a wide range of specialist business support. (uclan.ac.uk)
Effective1
- Managing pain from chronic conditions, such as, but not limited to, osteoarthritis and rheumatoid arthritis, requires the clinician to balance the need for effective analgesia against safety risks associated with analgesic agents. (openrheumatologyjournal.com)
Potential1
Products1
- Antidepressive medicinal products should continue for at least six months following remission. (tajgenerics.com)
Journal2
- Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. (mdpi.com)
- The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal. (mdpi.com)
Class1
- We offer a vibrant and world-class research environment, matched by excellent facilities, comprehensive research support and award-winning training opportunities. (uclan.ac.uk)
Article2
Antidepressant agent1
- Although it is chemically a classical tricyclic antidepressant agent, trimipramine shows atypical pharmacological properties. (nih.gov)
Atypical1
- Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. (drugbank.com)
SSRI1
- The increased risk was particularly notable for the selective serotonin-reuptake inhibitor (SSRI) paroxetine and the tricyclic antidepressant amitriptyline. (survivingantidepressants.org)
Compounds1
- The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. (edu.au)
Antipsychotic3
- To evaluate the association between antipsychotic and antidepressant agents and the risk of hip fracture in older adults, across multiple studies. (medscape.com)
- An English-language PubMed/MEDLINE search for studies from January 1966 to January 2011 was conducted, using key words including aged, hip fracture, fractures, antidepressive agents, and antipsychotic agents, as well as individual drug names. (medscape.com)
- A thioxanthine used as an antipsychotic agent. (drugbank.com)
Norepinephrine1
- Patients with anergic dysthymia, the authors suggest, may have a better response to treatment with agents that increase norepinephrine or dopamine. (medscape.com)
Psychotropic agents1
- meta-analysis, which included studies conducted up to 1996, many of the currently available second-generation psychotropic agents were unavailable or had not been studied sufficiently. (medscape.com)
Major depressi1
- SELECTION CRITERIA: All RCTs comparing fluoxetine with any other AD (including non-conventional agents such as hypericum) for patients with unipolar major depressive disorder (regardless of the diagnostic criteria used) were included. (ox.ac.uk)
Practice3
- Nevertheless, answering our research question is quite relevant for clinical practice and therapeutic prescription and should be further investigated especially considering the high drop-out rates in drug treatment. (frontiersin.org)
- For the study, researchers obtained data from United Kingdom's General Practice Research Database, which contains medical records for more than 6.4 million patients from about 450 general practices across the country. (survivingantidepressants.org)
- The assessment and treatment of back and neck pain: an initial investigation in a primary care practice-based research network. (omeka.net)
Treatment1
- To understand the changing patterns of preventive treatment following the introduction of these new agents, we must first characterize the patterns which preceded their introduction. (elsevierpure.com)
Grants1
Drug1
- Criteria for study inclusion were mean subject age greater than or equal to 65 years, adjusted for age and sex, hip fracture-specific results provided, data specific to a drug class, subclass, or single agents, and cohort or case-controlled study design. (medscape.com)
Environmental3
- If you are giving a presentation about an environmental health topic or just looking for general information about environmental health research or the institute, this page will help. (nih.gov)
- NIEHS is committed to conducting the most rigorous research in environmental health sciences, and to communicating the results of this research to the public. (nih.gov)
- NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
Topics2
Individual1
Introduction1
- The introduction of these agents in the market has passed through seemingly strict regulatory control. (biomedcentral.com)
Public2
- Fall prevention has received considerable attention in research and public policy, resulting in a large body of findings on risks for falling as well as clinical guidelines for fall prevention. (medscape.com)
- The WHO Covid-19 Research Database is a resource created in response to the Public Health Emergency of International Concern (PHEIC). (bvsalud.org)
Medical1
- 1. There is still very little legitimate, thorough medical research on this subject. (erowid.org)