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  • genome
  • The temporal order of replication of all the segments in the genome, called its replication-timing program, can now be easily measured in two different ways. (wikipedia.org)
  • Seven basic replication strategies exist based on genome type (including DNA or RNA and single‐ or double‐stranded genomes) but these may vary widely within a specific type. (els.net)
  • Genome instability is a hallmark of cancer, and DNA replication is the most vulnerable cellular process that can lead to it. (nih.gov)
  • Any condition leading to high levels of DNA damage will result in replication stress, which is a source of genome instability and a feature of pre-cancerous and cancerous cells. (nih.gov)
  • process
  • The process of duplicating DNA is called DNA replication , and it takes place by first unwinding the duplex DNA molecule, starting at many locations called DNA replication origins, followed by an unzipping process that unwinds the DNA as it is being copied. (wikipedia.org)
  • Figure D-1 and its accompanying text provides an overview of the Oracle Database Advanced Replication process. (oracle.com)
  • If you want to understand the chemical structure of life and why life appears the way that it does, you have to understand the process of DNA-replication. (brighthub.com)
  • Learn about the DNA replication steps to better understand the process. (brighthub.com)
  • An understanding of the process of DNA replication can help you gain basic knowledge about genetic engineering and how genetic mutations. (brighthub.com)
  • In this Review, we discuss the link between persistent replication stress and tumorigenesis, with the goal of shedding light on the mechanisms underlying the initiation of an oncogenic process, which should open up new possibilities for cancer diagnostics and treatment. (nih.gov)
  • crucial
  • Focusing on the fields of economics, political science, sociology and psychology, in which ready access to raw data and software code are crucial to replication efforts, we survey deficiencies in the current system. (nature.com)
  • Site
  • Local changes are distributed to a remote master site where the replication server, acting as a client, sends commands to the Oracle Internet Directory server that implements them. (oracle.com)
  • Authors
  • We propose reforms that can both encourage and reinforce better behaviour - a system in which authors feel that replication of software code is both probable and fair, and in which less time and effort is required for replication. (nature.com)
  • We also personally experienced antagonism between replicators and authors in a programme sponsored by the International Initiative for Impact Evaluation (3ie), a non-governmental organization that actively funds software-code replication. (nature.com)
  • The organization also offered the original authors the opportunity to review and comment on the replications. (nature.com)
  • Original authors of five studies wrote in public comments that the replications actively sought to refute their results and were nitpicking. (nature.com)
  • Although one effort replicated all the results in the original paper, the originating authors wrote, "we disagree with the unnecessarily aggressive tone of some statements in the replication report (particularly in the abstract)" (see go.nature.com/2esdjkr ). (nature.com)
  • database
  • Removes all metadata for tracer tokens older than the specified date from a database published using transactional replication. (microsoft.com)
  • Removes metadata for a specific tracer token from a database published using transactional replication. (microsoft.com)
  • Advanced Replication enables you to synchronize database tables across two Oracle databases. (oracle.com)
  • If it is appropriate for your deployment, Oracle recommends that you use LDAP-based replication instead of Oracle Database Advanced Replication-based replication for better performance. (oracle.com)
  • The Oracle Single Sign-On database schema that resides in the same database as Oracle Internet Directory is also replicated by Advanced Replication. (oracle.com)
  • The new change log is pushed From Replica A to Replica B through Oracle Database Advanced Replication. (oracle.com)
  • data
  • A smoothed line (blue) is drawn through the data to visualize the domains of different replication timing. (wikipedia.org)
  • For a flexible one-stop shop for high-volume, robust, secure information replication across heterogeneous data stores. (ibm.com)
  • Save those transactions in a replication log including changes that insert, delete, or update data. (ibm.com)
  • In fact, in the 11 top-tier economics journals we surveyed, we could find only 11 replication studies - in this case, defined as reanalyses using the same data sets - published since 2011. (nature.com)
  • stores
  • The consumer replication servers apply the remote changes to their own local directory servers, and then purge the applied remote changes from their local stores. (oracle.com)
  • cell
  • Replication timing is correlated with the expression of genes such that the genetic information being utilized in a cell is generally replicated earlier than the information that is not being used. (wikipedia.org)
  • provides
  • Although a negative aspect of replication stress is its prominent role in tumorigenesis, a positive aspect is that it provides a potential target for cancer therapy. (nih.gov)
  • better
  • While there may be a consensus in the industry that hedge funds clones will bring better liquidity and lower fees, it is still debatable whether replication products should serve as a complement in the hedge fund allocation decision or as a replacement. (springer.com)
  • questions
  • This week has been dominated by questions of replication and of what standards are required to serve the interests of transparency and/or science (not necessarily the same thing). (realclimate.org)
  • costs
  • Many authorities say that in the limit, the cost of self-replicating items should approach the cost-per-weight of wood or other biological substances, because self-replication avoids the costs of labor, capital and distribution in conventional manufactured goods. (wikipedia.org)