Repeated sequence. Medical search. Frequent questions

Simple Sequence Repeat (SSR) DNA markers or Microsatellites are di-, tri-, tetra-nucleotide tandem repeats containing loci of eukaryotic genomes. (tubitak.gov.tr)
The simple sequences and repetitive elements common to plant genomes are a major challenge, he said, noting that "it gives Illumina a fit and with PacBio it works well. (pacb.com)
Many genomes contain kilobases of DNA sequence that do not code for protein or RNA. (biomedcentral.com)
A large proportion of the genomes of species belonging to the genus Allium comprises repetitive sequence DNA, a component implicated as a cause of the large variation in C-values between even closely related species. (nottingham.ac.uk)
Data relating to the evolution and maintenance, functions and effects of repetitive-sequence DNA in eukaryotic genomes are reviewed and where possible the data pertaining to Allium are discussed in context with such information from other species. (nottingham.ac.uk)
Sequence analysis of the Daphnia pulex genome holds some surprises that could not have been anticipated from what was learned so far from other arthropod genomes. (biomedcentral.com)
Simple sequence repeats (SSRs) are highly variable features of all genomes. (biomedcentral.com)
Long terminal repeat (LTR) retroelements represent a successful group of transposable elements (TEs) that have played an important role in shaping the structure of many eukaryotic genomes. (biomedcentral.com)

Nanopore sequencing is an evolving third/fourth generation sequencing technology for direct detection of nucleotide sequences with kb or even Mb base pairs (7)(8) . (researchsquare.com)

From this experiment they find several thousand mononucleotide repeats of up to eight bases (for example, AAAAAA) and about 2300 trinucleotide repeats (for example GAT) which appear more often in the E. coli genome than expected by chance. (biomedcentral.com)
To provide the clinical diagnostics community with accurate protocols and measurements for the detection of genetic disorders, we have established a quantitative a quantitative measurement program for trinucleotide repeats associated with human disease. (nist.gov)
For example, a trinucleotide repeat is made up of sequences of three nucleotides, and a tetranucleotide repeat is made up of sequences of four nucleotides. (medlineplus.gov)
Here, we report the discovery of exonic GGC trinucleotide repeat expansions, encoding poly-glycine, in zinc finger homeobox 3 (ZFHX3) in these families. (lu.se)

There are two types of melodic sequences: real and tonal. (pressbooks.pub)

For minisatellites and microsatellites, the number of times the sequence repeats at a single locus can range from twice to hundreds of times. (wikipedia.org)
Short tandem repeats (STRs), also known as microsatellites, are repetitive DNA sequences consisting of 1-6-bp motifs present in a genome. (researchsquare.com)

Each SSR locus can easily be amplified by using a polymerase chain reaction (PCR) knowing the DNA sequence flanking the repeat region specifically. (tubitak.gov.tr)
Tandem repeats, which display a greater propensity to mutate, and are often hypomethylated in cancer patients, have never been investigated in individuals exposed to PM. We measured methylation of three tandem repeats (SATα, NBL2, and D4Z4) by polymerase chain reaction-pyrosequencing on blood samples from truck drivers and office workers (60 per group) in Beijing, China. (nih.gov)

It is demonstrated that these loci are very polymorphic due to the change in the number of repeating units among the individuals of populations. (tubitak.gov.tr)
Although NanoSTR needs further optimization and development, it is useful as an analytical method for the detection of STR loci by nanopore sequencing. (researchsquare.com)
These highly individual-specific number of repeats and the abundance of motifs have contributed to the polymorphism of STR loci. (researchsquare.com)

The only limiting feature of the application of these markers is the need for prior sequence information for developing primers in locus-specific PCR amplification. (tubitak.gov.tr)
This limitation is alleviated for the economically important species and the ones closely related, since primer sequences of the SSR DNA markers and the amplification conditions are available in the literature. (tubitak.gov.tr)
The genetic structure and variability was described among 52 oil palm inter-population crosses after two selection cycles using simple sequence repeats markers (SRR). (academicjournals.org)
In Specific Aim 1, we will characterize the modular domain organization of LCR22-2 and LCR22-4, by generating BAC based physical maps by screening filters containing BAC clones from different libraries, obtaining end sequence and typing with PCR markers. (elsevierpure.com)
In this study, 20 representative accessions of peach germplasm from the National Germplasm Repository of Peach in China were used to select a set of 18 simple sequence repeat (SSR) markers for accurate species discrimination. (ashs.org)
Soriano JM, Domingo ML, Zuriaga E, Romero C, Zhebentyayeva T, Abbott AG, Badenes ML. Identification of simple sequence repeat markers tightly linked to plum pox virus resistancein apricot. (rosaceae.org)
In this study, we generated 42 simple sequence repeat (SSR) markers from the peach genome assembly v1.0 and an apricot bacterial artificial chromosome clone identified in the physical map of the PPV resistance locus previously defined in apricot. (rosaceae.org)
Analysis of the publicly available genome sequence of Nipponbare near the Pi-z locus revealed numerous SSRs that could be converted into markers. (springer.com)
In this study, we assessed the diversity among sweet potato landraces from Kenya, Uganda and Tanzania using morphological and simple sequence repeats (SSR) markers. (mak.ac.ug)

Because the environment of one base in an SSR is a lot like that of its neighbors, the DNA replication machinery can confuse one base with another, skip a base or repeat replication of a base. (biomedcentral.com)

Repeated sequences (also known as repetitive elements, repeating units or repeats) are short or long patterns of nucleic acids (DNA or RNA) that occur in multiple copies throughout the genome. (wikipedia.org)
Much of this DNA is simple sequence repeats (SSRs), long repeats of simple nucleotide patterns. (biomedcentral.com)
Our results show that three groups of DNA attributes, namely certain sequence patterns, specific DNA repeats, and a particular DNA structure, are each highly correlated with CpG island methylation (correlation coefficients of 0.64, 0.66, and 0.49, respectively). (mpg.de)
The most important aspect of paying attention to repeating numbers is to recognize both the patterns and messages they contain. (alanmorrison.us)
We have assembled a Repeat Pattern Toolkit (RPT) to analyze the patterns of repeats occurring in DNA. (aaai.org)

However, an abundance of neutral repeats can still influence genome evolution as they accumulate over time. (wikipedia.org)

As a consequence, SSRs are more likely to mutate than are other DNA sequences. (biomedcentral.com)
A and T appear more often in these repeats than G and C. The putative SSRs were not randomly distributed in the genome. (biomedcentral.com)
Finally, the authors compare the sequences of 14 SSRs among 23 strains of E. coli . (biomedcentral.com)
argue that the SSRs they find near gene sequences are biologically important, but this needs to be confirmed by mutational analysis in vitro . (biomedcentral.com)

Our hypothesis, based upon preliminary data, is that there are clusters of shared polymorphic sequences (SPSs) between the two LCR22s, representing intervals of enhanced historic gene conversion events. (elsevierpure.com)
The availability of this extended region of contiguous sequence has allowed us to analyze the nature and prevalence of repetitive sequences in the genome of a eukaryotic organism with a high gene density. (aaai.org)
This cDNA can then be fluorescently labeled and hybridized to the target gene sequences on the microarray. (medscape.com)
The DNA sequence of a gene can be altered in a number of ways. (medlineplus.gov)
changes the DNA sequence by adding one or more nucleotides to the gene. (medlineplus.gov)
changes the DNA sequence by removing at least one nucleotide in a gene. (medlineplus.gov)
occurs when a stretch of one or more nucleotides in a gene is copied and repeated next to the original DNA sequence. (medlineplus.gov)
An inversion changes more than one nucleotide in a gene by replacing the original sequence with the same sequence in reverse order. (medlineplus.gov)

In summary, our results suggest that DNA composition of CpG islands (sequence, repeats, and structure) plays a significant role in predisposing CpG islands for DNA methylation. (mpg.de)

One challenge for this plant is its 3 Mb of rDNA repeats. (pacb.com)
You can never assemble rDNA repeats," Albert said of other sequencing platforms. (pacb.com)

When the repeating sequence is only 2-10 nucleotides long, the repeat is referred to as a short tandem repeat (STR) or microsatellite. (wikipedia.org)
Measuring tandem-repeat hypomethylation in easy-to-obtain blood specimens might identify individuals with biological effects and potential cancer risk from PM exposure. (nih.gov)

Similarly, their polymorphism results might be diagnostically useful as probes to distinguish between E. coli strains, but probes to long repeat sequences can cross-react, so it might be difficult to put this idea into practice. (biomedcentral.com)

The presence of repeated sequence DNA makes it easier for areas of homology to align, thereby controlling when and where recombination occurs. (wikipedia.org)
In addition to playing an important role in recombination, tandem repeats also play important structural roles in the genome. (wikipedia.org)
Non-allelic homologous recombination (NAHR) events between two, 240 kb low copy repeats, termed LCR22-2 and LCR22-4, mapping 3 Mb apart, lead to several genomic disorders including velo-cardio-facial/DiGeorge syndrome (VCFS/DGS), occurring in 1/4,000 live births. (elsevierpure.com)

See how the University of Washington used HiFi sequencing to uncover a key finding about ALS and the human genome. (pacb.com)
Researchers from China and the US have produced the first broad benchmark of genomic and metagenomic assemblers specifically for PacBio HiFi sequence data. (genomeweb.com)

A repetition of the melodic material takes the original material and either repeats it so that it is exactly the same, or repeats it so that it is primarily the same but is transposed so that it starts on a different pitch. (pressbooks.pub)
Bar 6 repeats bar 5 starting on a different pitch level, so is labeled as a repetition (R). Bar 7 consists of new material (N). Bar 9 looks a lot like bar 5, but is decorated with a grace note and has a different rhythm. (pressbooks.pub)
The repeat units are not tandemly arranged but are juxtaposed and inserted by unrelated sequences of high repetition. (ox.ac.uk)

Some repetitive elements are neutral and occur when there is an absence of selection for specific sequences depending on how transposition or crossing over occurs. (wikipedia.org)
McClintock's work set the stage for the discovery of repeated sequences because transposition, centromere structure, and telomere structure are all possible through repetitive elements, yet this was not fully understood at the time. (wikipedia.org)
We label sequences by their type as well as their interval of transposition. (pressbooks.pub)
To name the level of transposition, look at the first note of the statement in comparison to the first note of the sequence. (pressbooks.pub)

In this article we will be focusing our attention to using sequences with repeating motives. (delcoguitaracademy.com)

Although the complete sequence of the two LCR22s is available for two alleles of chromosomes 22 and it allowed us to generate this hypothesis, it is insufficient to test it. (elsevierpure.com)
To test our hypothesis, we propose to generate the finished sequence of LCR22-2 and -4 from additional normal alleles of chromosome 22 from existing BAC libraries, roughly 4.4 Mb of sequence. (elsevierpure.com)
In Specific Aim 2, the minimal tiling path of BAC clones encompassing five alleles will be sequenced and a variation map containing all the insertions, deletions or inversions as well as nucleotide polymorphisms, will be generated. (elsevierpure.com)
Non-expanded alleles carried one or more interruptions within the repeat. (lu.se)

This thematic series of companion papers constitutes the initial exploration of the genome biology of the waterflea (Daphnia) building on the first complete crustacean genome sequence. (biomedcentral.com)

Tandem repeats may vary in the number of nucleotides comprising the repeated sequence, as well as the number of times the sequence repeats. (wikipedia.org)
When the repeating sequence is 10-60 nucleotides long, the repeat is referred to as a minisatellite. (wikipedia.org)
Some regions of DNA contain short sequences of nucleotides that are repeated a number of times in a row. (medlineplus.gov)

DNA-dispersed repeats were increasingly recognized as a potential source of genetic variation and regulation. (wikipedia.org)
Structural and sequence variation within the two LCR22s has not been defined. (elsevierpure.com)
Bar 11 looks like the material in b. 7, but with variation in rhythm and contour, so it called a variation (V). Look at the example below and listen to the recording again to see if you can hear the differences between creating new material, varying the material, and repeating the material. (pressbooks.pub)

ANGEL NUMBERS - A Guide to Repeating Number Sequences and their Messages and Meanings. (blogspot.com)
We'll examine how these sequences can offer guidance and insight into our lives, and explore the different types of sequences and their meanings. (alanmorrison.us)

In the 1990s, more research was conducted to elucidate the evolutionary dynamics of minisatellite and microsatellite repeats because of their importance in DNA-based forensics and molecular ecology. (wikipedia.org)
Click molecule labels to explore molecular sequence information. (nih.gov)
The repeat contains a G + C-rich reiterated sequence, an A + T-rich sequence with the potential of forming a hairpin structure which may form part of an origin of DNA replication, and three open reading frames predicted to encode primary translation products with approximate molecular weights of 140 000, 30 000 and 20 000. (gla.ac.uk)
These interruptions in the perfect repeating sequence could possibly be practical, and also have been recommended to perform a part in molecular versatility, formation of networkNIH-PA Author Manuscript NIH-PA Writer Manuscript NIH-PA Author ManuscriptJ Struct Biol. (dot1linhibitor.com)
Unusual molecular characteristics of a repeat sequence island within a Giemsa-positive band on the mouse X chromosome. (ox.ac.uk)

such sequences display quantitative and qualitative modulations in their organisation. (nottingham.ac.uk)

Continuing the avian theme, Duke's Erich Jarvis spoke about the B10K project, an effort to sequence every species of bird on the planet. (pacb.com)
The work presented here represents part of the first phase in the characterisation of some of these repetitive sequences in a number of Allium species. (nottingham.ac.uk)

repetitive sequence elements in the members had been in contact with bacterial genome have shown con- patients for several hours. (who.int)

His lab has found that PacBio sequencing produces genome assemblies of much higher quality than those from short-read data (in some cases increasing the contig N50 from as little as 30 kb to as much as 10 Mb, and reducing contig counts from more than 120,000 to about 1,000). (pacb.com)
As practice, I wrote this function that produces a repeatable sequence of prime numbers (i.e. the sequence can be iterated multiple times, and will make use of results from past iterations to speed up future iterations). (stackexchange.com)

O made use of to investigate the effect of interruptions during the Gly-Xaa-Yaa repeating sequence on triple-helix conformation, stability and folding (Hwang and Brodsky, 2012). (dot1linhibitor.com)

Join us on this journey as we uncover the secrets and power of number sequences. (alanmorrison.us)

The disposition of repetitive elements throughout the genome can consist either in directly adjacent arrays called tandem repeats or in repeats dispersed throughout the genome called interspersed repeats. (wikipedia.org)
DNA microarrays are simply platforms that consist of small solid supports onto which the sequences from thousands of different genes are attached at fixed locations. (medscape.com)

A statistical analysis of simple repeat motifs in DNA across the Escherichia coli genome is described. (biomedcentral.com)
Of the many motifs that were explored, the urea protection scheme proved to be the most amenable to the coupling reactions required to prepare segmer units with a para-ortho-para sequence. (pitt.edu)

The introduction of complementary DNA (cDNA) microarray technology in 1995 has helped to facilitate the identification and classification of DNA sequence information and the assignment of functions to these new genes by allowing investigators to analyze expression of thousands of genes simultaneously in a single experiment. (medscape.com)

We also found ZFHX3 repeat expansions in three additional families, all from the region of Skåne in southern Sweden. (lu.se)
Our findings demonstrate that SCA4 is caused by repeat expansions in ZFHX3. (lu.se)

This process is repeated to build specific oligonucleotide sequences. (medscape.com)
This process is repeated as needed to widen the bore. (cdc.gov)

These are computer-generated random strings of sequence with the same nucleotide composition as the real E. coli genome. (biomedcentral.com)
I am using After effects and I have imported the image sequence, made a composition (30fps, 2 min long) changed the time remapping so each drawing is displayed during 15 frames (0.5 seconds). (stackexchange.com)

They then compare SSR sequences from several strains of E. coli , and report the polymorphisms - the sequence differences - between strains. (biomedcentral.com)
The number of repeat units differs between individuals, resulting in highly complex allele polymorphisms. (researchsquare.com)
In practice, however, the high error rate and special data characteristics of long-read sequencing have limited the efficient identification of STR polymorphisms, and therefore, further evaluation of the analytical methods is required (9)(10) . (researchsquare.com)

Short tandem repeats (STRs) are widely present in the human genome. (researchsquare.com)
DESCRIPTION (provided by applicant): Low copy repeats (LCRs;also known as segmental duplications) constitute roughly 5% of the human genome and are known to mediate chromosome rearrangements associated with mental retardation disorders. (elsevierpure.com)

In the 2000s, the data from full eukaryotic genome sequencing enabled the identification of different promoters, enhancers, and regulatory RNAs which are all coded by repetitive regions. (wikipedia.org)
There are a few methods for STR identification based on nanopore sequencing, and the representative software are Tandem-Genotypes (11) , NanoSatellite (12) , STRique (13) ， etc. (researchsquare.com)

NanoSTR can be used for STR detection and genotyping based on long-read data from nanopore sequencing with improved accuracy and efficiency compared with other existing methods, such as Tandem-Genotypes and TRiCoLOR. (researchsquare.com)
The mouse genome contains 50 copies of a long complex repeat unit localized as a repeat sequence island to the A3 Giemsa-positive (dark) band on the mouse X chromosome. (ox.ac.uk)
second, it features a high concentration of L1 long interspersed repeat sequences. (ox.ac.uk)
Anticipation was observed in all families and correlated with different repeat lengths determined through long-read sequencing in two family members. (lu.se)

However, there are few methods for STR detection based on nanopore sequencing due to the challenges posed by the sequencing principles and the data characteristics of nanopore sequencing. (researchsquare.com)
In terms of data characteristics, NanoSTR effectively avoids the non-random sequencing errors and unexpected insertions-deletions (indels) associated with nanopore sequencing (8)(9) and thus improves the efficiency of sequencing data utilization, the detection rate of STR genotypes, and the accuracy of STR profiling. (researchsquare.com)

Over 3.6 million bases of DNA sequence from chromosome III of the C. eleganshave been determined. (aaai.org)

Nevertheless, occasionally some repeats may be exapted for other functions. (wikipedia.org)
O n the Math 1 test, there is often one and occasionally two questions about sequences. (schoolbag.info)

Sequences flanking these clusters would be unique to one LCR or the other and would be marked by paralogous sequence variants (PSVs). (elsevierpure.com)

El estudio investigó, en un recorte longitudinal, modelos predictivos de la competencia aritmética (CA) en el primer año a partir de habilidades de lenguaje y funciones ejecutivas evaluadas en edad preescolar. (bvsalud.org)
En el primer año, los niños también se evaluaron en CA. Los padres proporcionaron información sobre NSE y los profesores indicaron a los niños con dificultades en el curso de la EI. (bvsalud.org)

The event was a hit with customers and PacBio staff alike, and discussions we heard in the hallways and during breaks told us there was some great knowledge exchange that should give labs inspiration for generating and analyzing their SMRT Sequencing data. (pacb.com)
He offered some historical perspective on throughput improvements over time for the SMRT Sequencing platforms (believe it or not, throughput has increased 100x in the past five years) and shared some data produced by the Sequel System. (pacb.com)

has been identified as the 2nd most consensus (ERIC) sequences which · 60 environmental samples were tak- frequent organism causing ventilator- are common to Gram-negative enteric en throughout the ICU, including associated pneumonia, the 4th most bacteria [11,12]. (who.int)

Today, the structural and regulatory roles of repetitive DNA sequences remain an active area of research. (wikipedia.org)
Introduction of biological practical sequences Animal collagen may be the big cIAP-1 Antagonist supplier structural protein delivering physical help of tissues, and in addition has a variety of biological functions by interacting with cell surface receptors and also other extracellular matrix molecules. (dot1linhibitor.com)

Overall, repeated sequences are an important area of focus because they can provide insight into human diseases and genome evolution. (wikipedia.org)
Concerted evolution refers to the pattern in which copies of multigene families show high intraspecific sequence homogeneity but high interspecific sequence diversity. (biomedcentral.com)
The tools include identifying significant local alignments (utilizing both two-way and three-way alignments), dividing the set of alignments into connected components (signifying repeat families), computing evolutionary distance between repeat fanfily members, constructing minimum spanning trees from the connected components, and visualizing the evolution of the repeat families. (aaai.org)
Evolution of repeated DNA sequences by unequal crossover. (bvsalud.org)

On the Math 1 test, the most common type of question concerning sequences gives you a rule and asks you to find a particular term. (schoolbag.info)

STs, sequence types. (cdc.gov)
The three types of sequences that occur most often are repeating sequences, arithmetic sequences, and geometric sequences. (schoolbag.info)
By understanding the significance of repeating numbers and other types of sequences, you can tap into the power of numerology and potentially improve your life. (alanmorrison.us)
En Égypte, les isolats des patients étaient de types ERIC VII, VIII et IX et correspondaient à ceux des tubulures des appareils d'aspiration et de respiration artificielle et des cuvettes. (who.int)

In this blog post, we'll delve into the world of number sequences and their deep spiritual and numerological significance. (alanmorrison.us)
Exploring the significance of repeating numbers can offer a moment of stillness and introspection, a chance to connect with something bigger than ourselves. (alanmorrison.us)

The major inverted repeat of 7319.5 base pairs is present at an internal site in the varicella-zoster virus genome and at one terminus. (gla.ac.uk)
A DNA sequence of 7747 base pairs containing the repeat was determined and analysed. (gla.ac.uk)

Although the repetitive DNA sequences were conserved and ubiquitous, their biological role was yet unknown. (wikipedia.org)
Tandem repeats have a wide variety of biological functions in the genome. (wikipedia.org)
For instance, in some S. pyogenes strains, the CL domain of Scl1 protein can interact with integrins 21 and 111 as a IL-17 Inhibitor Biological Activity result of the sequence GLPGER (Caswell et al. (dot1linhibitor.com)

With the bonus that also works in case the number sequence grows to more than two numbers. (microsoft.com)
The numbers in the list are called the terms of the sequence. (schoolbag.info)
These repeating numbers aren't just a coincidence - they hold significant meaning and power. (alanmorrison.us)
By understanding the power behind repeating numbers, we can tap into a deeper understanding of ourselves and the world around us. (alanmorrison.us)
When you begin to notice a repeated sequence of numbers, don't ignore it. (alanmorrison.us)
The next time you observe a specific sequence of numbers, take a moment to reflect on them, trust your intuition, and let the numbers guide you towards the right path in your life. (alanmorrison.us)
The universe speaks to us in many ways, and repeating numbers are one of them. (alanmorrison.us)
Embrace the power of repeating numbers! (alanmorrison.us)
Sequences with ascending or descending numbers, such as 123 or 987, suggest a path of progress and success. (alanmorrison.us)
The Seq (Sequence) field sequentially numbers chapters, tables, figures, and other items in a document. (microsoft.com)

In many organisms, a significant fraction of the genomic DNA is repetitive, with over two-thirds of the sequence consisting of repetitive elements in humans. (wikipedia.org)
One repetitive DNA sequence family, BIOOO, isolated from the genome of A. sativum, has been characterised with respect to the genomic organisation, reiteration frequency and sequence divergence of its members within A. sativum. (nottingham.ac.uk)
Understanding the basis for 22q11.2 rearrangements on the sequence level can serve as a model for other newly discovered genomic disorders, such as the reciprocal duplication disorder on 22q11.2 and elsewhere in the genome. (elsevierpure.com)

Anatomy10

Organisms11

Diseases1

Chemicals and Drugs47

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Phenomena and Processes85

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science5

Genomes8

Nucleotide sequences1

Trinucleotide4

Melodic Sequences1

Microsatellites2

Polymerase chain re2

Loci3

Markers9

Skip1

Patterns5

Abundance1

SSRs4

Gene8

Methylation1

RDNA2

Tandem repeat2

Probes1

Recombination3

HiFi2

Repetition3

Transposition4

Motives1

Alleles4

Genome sequence1

Nucleotides3

Variation3

Meanings2

Molecular5

Quantitative1

Species2

Repetitive-sequence1

Produces2

Interruptions1

Uncover1

Consist2

Motifs2

Genes1

Expansions2

Process is repeated2

Composition2

Polymorphisms3

Human genome2

Identification2

Long4

Detection2

Chromosome1

Occasionally2

Variants1

Primer2

Data2

Organism1

Structural2

Evolution4

Type1

Types4

Significance2

Base pairs2

Biological3

Numbers10

Genomic3