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  • oxidative stress
  • Our results indicate that the major pathogenic factors in the endothelial damage are oxidative stress and mitochondrial damage within endothelial cells, while mitochondria-targeted antioxidants could be an effective tool for the protection of tissue from negative effects of ischemia. (msu.ru)
  • laparoscopic
  • VRIS may be broadly applicable to provide an indicator of organ ischemia during open and laparoscopic procedures. (spiedigitallibrary.org)
  • 4 We describe a method of selective renal parenchymal clamping (SRPC) with a kidney clamp that can be adopted in open, conventional, or robot-assisted laparoscopic NSS. (hkmj.org)
  • Organ
  • Assessment of endothelial damage, its role in pathological changes in organ functioning, and approaches to normalization of endothelial and renal functions are vital problems that need to be resolved. (msu.ru)
  • hemodynamics
  • On the other hand, an inhibitor of NO-synthases, L-nitroarginine, abolished the positive effects of SkQR1 on hemodynamics and protection from renal failure. (msu.ru)
  • parenchyma
  • Vermooten suggested that peripheral encapsulated renal neoplasms could be excised locally while leaving a margin of normal parenchyma around the tumor. (cancerlink.ru)
  • In all cases, the renal blood flow autoregulation system is unable to maintain perfusion of renal parenchyma at the level corresponding to the energy requirement of the nephron. (msu.ru)
  • Methods
  • Animal experiments focus on understanding the mechanism behind IRI and try to find methods to minimize IRI either before, during or after ischemia. (biomedcentral.com)
  • 2 Various vascular control methods have been described to achieve a bloodless field for tumour dissection and excision, with the traditional way being renal hilar clamping (HC) that results in global renal ischaemia. (hkmj.org)
  • Different methods of regional ischaemia have been reported including manual compression and various parenchymal clamps. (hkmj.org)
  • complications
  • Complications, although rare, occur with renal biopsies. (biomedcentral.com)
  • At this time, however, PN was associated with significant complications, including renal bleeding, urinary fistula, and death as compared with total nephrectomy, which had a lower operative morbidity and satisfactory long-term results. (cancerlink.ru)
  • vivo
  • For in vivo studies, the Lewis renal graft was stored in 4°C Soltran preserving solution for 24 h and transplanted into the Lewis recipient, and the lungs were harvested 24 h after grafting. (asahq.org)
  • In vivo ischemia has a more significant influence on RNA integrity, and tumor tissues have different tolerances to pre-analytical variables. (springer.com)
  • biochemical
  • The mechanisms of renal damages are complex, multifactorial and interdependent leading to biochemical, structural and functional alterations. (springer.com)
  • failure
  • S.N was a 28-year-old female in End Stage Renal Failure (ESRF), with systemic lupus erythematosus and recurrent lower limb deep vein thrombosis since adolescence. (surgeryresearchjournal.com)
  • results
  • it results from the drastic reduction of blood pressure in systemic vasodilatation or heart disorders or in case of excessive vasoconstriction of renal vasculature. (msu.ru)
  • excision
  • In 1887, Czerny was the first to use PN for excision of a renal neoplasm when he successfully removed an angiosarcoma from the upper third of the right kidney of a gardener. (cancerlink.ru)