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TumorsPartial nephrectomyVeinPapillaryPerirenalWilmsPrimary renalTubularLesionsNeoplasmsBilateralSpecimenKidneyBenignMalignancyDiagnosisOriginatesChromophobePelvisSuccinateMimicVesselsUncommonIndicativeCapsuleNodulesTissueFlank painRadiotherapyUltrasonographyDifferentiationProcedurePatientsRareCasesChoice
Tumors15
  • Renal oncocytomas are slow-growing tumors that tend to be small, unilateral, and asymptomatic. (medscape.com)
  • Oncocytosis is a rare condition characterized by multiple oncocytic tumors with histologic features, including renal oncocytoma, hybrid oncocytic tumor, and, occasionally, chromophobe RCC. (medscape.com)
  • Unfortunately, different renal tumors can have similar histologic features, making differential diagnostics challenging. (medscape.com)
  • Large tumors that extend beyond the midline, have vascular extension, or both are relative contraindications, since some surgeons elect to obtain tissue via surgical excision, but this may expose patients to increased surgical risks. (medscape.com)
  • In patients with bilateral Wilms tumors, solitary kidney, or kidney insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
  • Grossly, tumors presented as well-circumscribed solid masses, contained in the renal capsule in all cases. (journalmc.org)
  • Macroscopically, tumors presented as solid grayish white well-demarcated unencapsulated nodules with foci of hemorrhage in 2 cases. (journalmc.org)
  • Partial nephrectomy may be feasible in only 10%-15% of patients, as most tumors are too large at initial diagnosis. (medscape.com)
  • 3] In the presence of bilateral Wilms tumors, solitary kidney, or renal insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
  • Renal malakoplakia may imitate renal lead and tumors to needless surgery. (buyresearchchemicalss.net)
  • The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
  • The role of genotyping and ancillary tools, in particular immunohistochemistry, in correctly classifying these tumors is highlighted in the section on Renal Cell Carcinoma. (abdominalkey.com)
  • More than 80% of renal tumors of childhood are Wilms tumor (nephroblastoma) ( 1 , 2 ). (abdominalkey.com)
  • Synovial sarcoma and sarcomatoid renal cell carcinoma may be indistinguishable on pure histologie and immunohistochemical grounds, but these tumors contain distinctly different sets of chromosomal abnormalities. (the-medical-dictionary.com)
  • Fifteen of the 16 previous cases of primary renal SS were diagnosed using reverse-transcription polymerase chain reaction to detect the SYT-SSX gene fusion transcript caused by the t(X;18) translocation,2,3 whereas in the one remaining case a t(X;18) translocation was identified by cytogenetic analysis but no further karyotypic details were published.2 Therefore, the background cytogenetic profile of these tumors was unknown. (the-medical-dictionary.com)
Partial nephrectomy4
Vein3
  • The tumor extends into the renal vein in 40% of cases. (medscape.com)
  • There was no invasion in the surrounding perinephric fat or in the renal vein in the hilum. (journalmc.org)
  • Perirenal extension and renal vein thrombosis have been reported. (buyresearchchemicalss.net)
Papillary2
  • Papillary adenomas are also benign renal neoplasms, but they arise from the renal tubular epithelium and almost always are located within the cortex. (medscape.com)
  • Other genetically linked conditions also increase the risk of RCC, including hereditary papillary renal carcinoma, hereditary leiomyomatosis, Birt-Hogg-Dube syndrome, hyperparathyroidism-jaw tumor syndrome, familial papillary thyroid carcinoma, von Hippel-Lindau disease and sickle cell disease. (wikipedia.org)
Perirenal1
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
Wilms9
  • Wilms tumor is rare in adults, accounting for only 0.5% of renal lesions. (medscape.com)
  • Gross nephrectomy specimen shows a Wilms tumor pushing the normal renal parenchyma to the side. (medscape.com)
  • Wilms tumor arises from the primitive embryonal renal tissue. (medscape.com)
  • Grossly, Wilms tumor is typically an intrarenal solid or cystic mass, which may displace and, in rare cases, invade the renal collecting system. (medscape.com)
  • According to the NWTSG protocol, the first step in the treatment of Wilms tumor is surgical staging followed by radical nephrectomy, if possible. (medscape.com)
  • A three-year old child presents with a large renal mass suspected to be a Wilms tumor. (pedsurglibrary.com)
  • Surgical resection is performed and pathologic evaluation shows completely resected Wilms tumor with focal penetration of the renal capsule. (pedsurglibrary.com)
  • Children with which of the following conditions should receive screening renal ultrasounds for nephroblastoma (Wilms tumor)? (pedsurglibrary.com)
  • Wilms tumor usually presents as an asymptomatic abdominal mass in an otherwise healthy child. (pedsurglibrary.com)
Primary renal4
  • Oncocytoma is the most common benign solid renal tumor and accounts for 3-7% of all primary renal neoplasms. (medscape.com)
  • Most previous cases of primary renal synovial sarcoma were confirmed by molecular biology techniques, which detected the SYT-SSX gene fusion transcript typical of this tumor, but no details of the other chromosomal anomalies have been published. (the-medical-dictionary.com)
  • If primary renal SS is indeed a form of sarcomatoid differentiation that arises from renal cell carcinoma (RCC), then it is reasonable to expect that the t(X;18)(p11.2:q11.2) translocation associated with the SS phenotype would occur within a cytogenetic profile characteristic of the underlying RCC subtype. (the-medical-dictionary.com)
  • VVe present a case of primary renal SS assessed by standard cytogenetic analysis, which confirms a karyotype that is characteristic of SS as opposed to RCC with or without further genetic aberrations. (the-medical-dictionary.com)
Tubular3
  • Mucinous tubular and spindle cell carcinoma of the kidney is a rare and a distinctive renal tumor with a relatively indolent behavior. (journalmc.org)
  • Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare variant of renal cell carcinoma, which has recently been described in case reports or small series [ 1 ]. (journalmc.org)
  • The tumour arises from the cells of the proximal renal tubular epithelium. (wikipedia.org)
Lesions4
  • This technique assists in detection and localization of the tumor, and CT scanning may help in characterizing the mass, especially if fat-containing lesions (eg, angiomyolipomas) are present. (medscape.com)
  • Commonly, multiple poorly defined renal lesions enlarging the kidney, and often involving both kidneys, are present. (buyresearchchemicalss.net)
  • The renal lesions can distort the pelvis and calices but seldom cause obstruction. (buyresearchchemicalss.net)
  • Focal renal lesions are usually poorly defined and hypoechoic on ultrasound study. (buyresearchchemicalss.net)
Neoplasms1
  • Imaging characteristics of oncocytoma and RCC overlap, and differentiating an oncocytoma from an RCC and other solid renal neoplasms is not always possible with ultrasonography, CT scanning, or magnetic resonance imaging (MRI). (medscape.com)
Bilateral2
  • If imaging studies demonstrate bilateral disease, nephrectomy is not performed, but biopsy specimens are obtained. (medscape.com)
  • Bilateral renal involvement by tumor is present at diagnosis. (pedsurglibrary.com)
Specimen1
  • b) blood vessels within the specimen outside of the parenchyma contain tumor. (pedsurglibrary.com)
Kidney4
  • Although end-stage kidney disease after unilateral radical nephrectomy is uncommon (0.25% in the NWTSG trial), preserving healthy kidney tissue may prevent this complication, especially in patients with an underlying intrinsic kidney disease (eg, WAGR [Wilms tumor, aniridia, genitourinary anomalies, and mental retardation] syndrome, Denys-Drash syndrome). (medscape.com)
  • Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. (wikipedia.org)
  • 7, 8] A complete surgical procedure can be performed by laparoscopy when the tumor is small, allowing a first approach to the renal vessels without mobilization of the kidney. (medscape.com)
  • An ultrasound research of his still left kidney uncovered a hypoechoic heterogeneous mass in top of the pole calculating 6254mm. (buyresearchchemicalss.net)
Benign1
  • In addition, preliminary but encouraging data indicate that a laparoscopic approach to nephrectomy in benign disease is associated with decreased lengths of hospital stay and analgesic requirements in the pediatric patient. (medscape.com)
Malignancy1
  • All patients were female without history of genitourinary or renal malignancy. (journalmc.org)
Diagnosis6
  • As a result of variations in its classic appearance, difficulty in standardizing diagnostic criteria, and entities that mimic oncocytoma, such as eosinophilic variant chromophobe renal cell carcinoma (RCC) and succinate dehydrogenase-deficient RCC, pathologic diagnosis remains a challenge. (medscape.com)
  • Histological slides were reviewed and diagnosis of renal MTSCC was based on the criteria established by the WHO classification system [ 2 , 3 ]. (journalmc.org)
  • diagnosis was renal malakoplakia. (buyresearchchemicalss.net)
  • The medical diagnosis of malakoplakia should be considered for patients delivering using a renal mass and NOTCH1 a brief history of long-term repeated renal attacks or renal failing [4]. (buyresearchchemicalss.net)
  • The patient inside our survey Gemcitabine HCl novel inhibtior acquired renal malakoplakia but underwent a nephrectomy using the scientific medical diagnosis of a renal tumor. (buyresearchchemicalss.net)
  • A nephrectomy could be a choice for unifocal malakoplakia, however the preoperative medical diagnosis of renal malakoplakia in suitable scientific configurations can prevent needless surgery. (buyresearchchemicalss.net)
Originates1
Chromophobe1
  • With more than 95% confidence, the nested pattern, myxoid stroma, granular cytoplasm, and round nuclei are likely indicative of renal oncocytoma, whereas varying nuclear size, raisinoid nuclei, and reticular cytoplasm indicate a higher likelihood of chromophobe RCC. (medscape.com)
Pelvis1
  • The ureteric bud divides and branches forming the collecting system (renal pelvis, infundibulae, calyces, and tubules) for urine drainage. (esur2023.com)
Succinate2
  • Succinate dehydrogenase-deficient (SDH-deficient) renal cell carcinoma (RCC) is a rare subtype of RCC. (sajo.org.za)
  • Succinate dehydrogenase- (SDH)-deficient renal cell carcinoma (RCC) is a rare subtype of RCC, estimated to comprise 0.05% - 0.2% of all cases of RCC globally. (sajo.org.za)
Mimic1
  • The large, rapidly Gemcitabine HCl novel inhibtior growing nodules of malakoplakia may mimic renal cell carcinoma in imaging studies. (buyresearchchemicalss.net)
Vessels1
Uncommon1
  • A unifocal renal lesion is usually uncommon and can resemble a necrotic renal cell carcinoma [1]. (buyresearchchemicalss.net)
Indicative1
  • It is now known that this classic triad of symptoms only occurs in 10-15% of cases, and is usually indicative that the renal cell carcinoma (RCC) is in an advanced stage. (wikipedia.org)
Capsule1
Nodules1
  • Gross inspection of the lesion discloses gentle tan-yellow homogenous plaques and confluent nodules that are often significantly less than 1cm in size but can range up to 3 to 4cm and replace huge regions of renal Gemcitabine HCl novel inhibtior parenchyma. (buyresearchchemicalss.net)
Tissue2
  • The cut surface is typically solid, soft, and gray or pink, with a texture and appearance resembling brain tissue. (abdominalkey.com)
  • The ureteric bud grows laterally and invades the center of the metanephric blastema, the primordial renal tissue [4]. (esur2023.com)
Flank pain2
  • The initial symptoms of RCC often include blood in the urine (occurring in 40% of affected persons at the time they first seek medical attention), flank pain (40%), a mass in the abdomen or flank (25%), weight loss (33%), fever (20%), high blood pressure (20%), night sweats and generally feeling unwell. (wikipedia.org)
  • This classic triad is 1: haematuria, which is when there is blood present in the urine, 2: flank pain, which is pain on the side of the body between the hip and ribs, and 3: an abdominal mass, similar to bloating but larger. (wikipedia.org)
Radiotherapy1
  • First-line therapy included radical prostatectomy or radiotherapy ± androgen deprivation therapy in 14 (74 %) subjects. (bvsalud.org)
Ultrasonography1
  • Imaging exploration (ultrasonography and computed tomography scan) showed a well-circumscribed renal mass ( Fig. 1 ) in all the cases (3 left-sided and 1 right-sided mass). (journalmc.org)
Differentiation1
  • CT scanning also helps in detection of calcifications and in differentiation of a complex cyst from a solid neoplasm. (medscape.com)
Procedure1
  • Through the procedure, the mass was noticed mounted on his descending digestive tract and psoas muscles. (buyresearchchemicalss.net)
Patients5
  • About one third of patients have signs and/or symptoms, with flank/abdominal pain, hematuria, and/or a flank mass among the most common. (medscape.com)
  • All patients were treated by nephrectomy (radical in 2 cases and partial in 2 cases). (journalmc.org)
  • Conclusion Renal malakoplakia must be kept in mind for patients presenting with a renal mass and a history of long-term recurrent renal infections or renal failure. (buyresearchchemicalss.net)
  • Since this is a relatively rare type of cancer, large studies haven't been conducted, but, from the number of cases reported, there is usually a swelling around the affected area, and often there is pain or discomfort (however, some patients can have no pain or discomfort at all). (the-medical-dictionary.com)
  • Coadministration of sodium polystyrene and antacids (calcium carbonate and magnesium oxide, in this case) has been reported to cause metabolic alkalosis in patients with end-stage renal disease and advanced stages of CKD. (abdominalkey.com)
Rare1
  • Large oncocytomas are rare and can be difficult to distinguish from RCCs on the basis of clinical findings or imaging characteristics alone. (medscape.com)
Cases1
  • When this occurs, origin of this unusual tumor type has been the subject of debate in the literature, with a suggestion that previously reported cases may be more correctly described as renal cell carcinoma with sarcomatoid dedifferentiation. (the-medical-dictionary.com)
Choice1
  • Computed tomography (CT) scanning of the abdomen, combined with intravenous administration of iodinated contrast medium, is the examination of choice and the best modality for evaluating a solid renal mass. (medscape.com)