• For specific dosing information in patients with renal impairment, refer to the product information of the co-administered protease inhibitor. (who.int)
  • Need to decrease dose in patients with renal impairment. (cdc.gov)
  • KEYTRUDA plus LENVIMA is approved in the U.S., the EU, Japan and other countries for the treatment of advanced renal cell carcinoma (RCC) and certain types of advanced endometrial carcinoma. (streetinsider.com)
  • Darmstadt, Germany and New York, US, May 14, 2019 - Merck KGaA, Darmstadt, Germany, which operates its biopharmaceutical business as EMD Serono in the US and Canada, and Pfizer Inc. (NYSE: PFE) today announced that the US Food and Drug Administration (FDA) has approved BAVENCIO® (avelumab) in combination with INLYTA® (axitinib) for the first-line treatment of patients with advanced renal cell carcinoma (RCC). (pfizer.com)
  • Opdivo and Opdivo -based combinations are important treatment options with established benefit across many cancer types, including melanoma, renal cell carcinoma, non-small cell lung cancer, mesothelioma, head and neck cancer, and bladder cancer, as well as esophageal, gastric, and gastroesophageal junction cancers. (bms.com)
  • Cases of myopathy and rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported. (nih.gov)
  • Myositis and rhabdomyolysis are the same forms of myopathy, with rhabdomyolysis being a more severe form of myopathy. (qscience.com)
  • We suggest that myopathy, in the form of myositis, should be recognized as a potential side effect of gabapentin in the literature. (qscience.com)
  • Qiu X, Tackett E, Zeid K. A case of gabapentin overdose induced rhabdomyolysis requiring renal replacement therapy. (qscience.com)
  • A. algerae has emerged as a cause of myositis, particularly in coastal Australia. (cdc.gov)
  • Acute renal failure (ARF) is a frequent tients who required kidney biopsy. (who.int)
  • Snakebite, malaria, liver diseases and Multivariate logistic regression analysis road traffic accidents are common health was carried out to study potential factors problems in Saudi Arabia [ 7-9 ], and the that might affect survival of acute renal contribution of these conditions to the de- failure. (who.int)
  • His course of illness was complicated with septic shock, acute renal failure, acute respiratory distress syndrome and disseminated intravascular coagulation and he succumbed to his illness on the eighth day of admission. (biomedcentral.com)
  • We describe a renal transplant recipient who presented with tropical myositis and acute allograft dysfunction 2(1/2) years after transplantation. (symptoma.com)
  • Scleroderma renal crisis is a true medical emergency in rheumatology, one that requires prompt diagnosis and treatment. (the-rheumatologist.org)
  • Patients with renal and central nervous involvement were excluded from the study. (bmj.com)
  • Significant renal and neurologic involvement was uncommon. (nih.gov)
  • Organisms also were seen in the alveolar septae, renal tubular cells, and parenchyma of the adrenal glands and liver ( 10 ). (cdc.gov)
  • 2011. Renal tubular dysfunction in patients with American cutaneous leishmaniasis. (ajtmh.org)
  • Valencia Deray KG , Taylor MG , Blessing MM , Bocchini CE , Schallert EK, Ruderfer D , Srivaths PR , Malatesta Muncher R . Necrotizing enterovirus myositis in a pediatric renal transplant recipient. (viictr.org)
  • While there is a recently described association of statin use with an immune-mediated necrotizing myositis through the formation of an autoantibody against HMG-CoA Reductase, this epidemiological study aimed to look at the incidence of statin use against all confirmed cases of IIM. (the-hospitalist.org)
  • 2014. Preliminary study on tubuloglomerular dysfunction and evidence of renal inflammation in patients with visceral leishmaniasis. (ajtmh.org)
  • Particular toxicity is seizures, primarily in renal failure or in the face of ongoing or preceding mind harm [url=https://dit.edu.ng/docs/purchase-cheap-kamagra-gold-online-no-rx/] erectile dysfunction doctors in massachusetts buy kamagra gold on line[/url]. (ehd.org)
  • multi-organ failure (septic shock, renal failure, respiratory failure). (cdc.gov)
  • citation needed] Myositis: Myalgias - muscular aches and pains - are common, but in the majority of patients muscular debilitation, electromyographic alterations, and elevations in muscular enzymes, like in pure polymyositis are not observed. (wikipedia.org)
  • Renal excretion is the primary route of elimination, whether aminocaproic acid is administered orally or intravenously. (globalrph.com)
  • Cases were divided into community-ac- spite substantial advances in renal replace- quired ARF, defined as renal failure devel- ment therapy and health care delivery, oping outside the hospital, and hospital- morbidity and mortality rates associated acquired ARF, defined as renal failure that with ARF have remained high [ 1-3 ]. (who.int)
  • Patients with this rare autoantibody suffered from a homogenous overlap connective tissue disease defined by Raynaud phenomenon (32/32), features of scleroderma (31/32), arthritis (31/32, erosive in 9/32), myositis (28/32), lung restriction (25/32), calcinosis (15/32), and sicca (11/32). (nih.gov)
  • Background Awareness of renal disease in scleroderma dates back many years. (the-rheumatologist.org)
  • Clostridial soft-tissue infections include cellulitis, myositis, and clostridial myonecrosis. (msdmanuals.com)
  • A. algerae has caused severe myositis in patients taking immunosuppressive medication for rheumatoid arthritis or solid-organ transplantation ( 3 , 5 , 8 ). (cdc.gov)
  • There is mounting evidence of an infrequent side effect known as idiopathic inflammatory myositis (IIM), that requires immunosuppressive therapy rather than just discontinuation of the medication. (the-hospitalist.org)
  • We report a case of probable gabapentin-induced myositis in a patient with spinal cord injury who was on an increasing dose of gabapentin. (qscience.com)
  • Clostridial myositis (suppurative infection of muscle without necrosis) is most common among injection drug users. (msdmanuals.com)
  • For dogs that cannot tolerate doxycycline, initial therapy with a penicillin is appropriate, but this should be followed by a 2-wk course of doxycycline to eliminate the renal carrier phase of infection. (rodpub.com)
  • What is the association between exposure to statin medications and histologically confirmed idiopathic inflammatory myositis? (the-hospitalist.org)
  • There was a statistically significant association between statin use and the incidence of idiopathic inflammatory myositis, which suggests that this condition is a potential serious side effect of statin therapy. (the-hospitalist.org)
  • Association of statin exposure with histologically confirmed idiopathic inflammatory myositis in an Australian population. (the-hospitalist.org)
  • Cefepime Dosing in a Critically Ill Neonate Receiving Continuous Renal Replacement Therapy With the Cardio-Renal Pediatric Dialysis Emergency Machine (CARPEDIEM). (viictr.org)
  • This report was undertaken to tion, duration of renal failure and having study the pattern of ARF in hospitalized pa- concomitant liver disease were included tients in southern Saudi Arabia. (who.int)
  • Renal failure and liver disease are treated with fluid therapy and other supportive measures to maintain normal fluid, electrolyte, and acid-base balance. (rodpub.com)
  • citation needed] Renal disease: The absence of severe renal disease is a marker of MCTD. (wikipedia.org)
  • In patients with pre-existing renal disease, a greater than or equal to 2-fold elevation over the baseline level. (cdc.gov)
  • Gabapentin-induced myositis was diagnosed by a combination of new-onset generalized body pain with tenderness, an increase in creatine kinase, elevated myoglobin levels, and a score of 6 on the Naranjo adverse drug reaction probability scale. (qscience.com)
  • Decrease dosage in patients with impaired renal function. (cdc.gov)
  • Drugs that decrease renal function could decrease clearance. (cdc.gov)
  • A. algerae myositis was first described in 2004 in a patient from Pennsylvania, USA, who had rheumatoid arthritis ( 3 ). (cdc.gov)
  • First Recommendations for Cancer Screening in Myositis Issued The guideline defines individual patient risk stratification, screening approaches, and frequency. (medscape.com)
  • Successful Outpatient Treatment of Severe Diabetic-Foot Myositis and Osteomyelitis Caused by Extensively Dr. (amjcaserep.com)
  • dolutegravir will increase the level or effect of dofetilide by decreasing renal clearance. (medscape.com)
  • Renal clearance (116 mL/min) approximates endogenous creatinine clearance. (globalrph.com)
  • Elevated creatine kinase, myositis-specific antibodies, diagnostic muscle biopsy. (mhmedical.com)
  • Results were similar even when excluding necrotizing myositis, which already has a known association with statin use, which suggests that statin use could be associated with all types of IIM. (the-hospitalist.org)
  • A retrospective, population-based, case-control study was conducted that compared the incidence of histologically confirmed IIM identified from the South Australian Myositis Database in patients 40 years or older with known statin exposure (n = 221) against population-based controls obtained from the North West Adelaide Health Study. (the-hospitalist.org)
  • McHugh et al report describe a rare benign tumour in the upper back termed proliferative myositis (PM). Surveillance is the preferred option with reports suggesting PM spontaneously regresses. (imj.ie)