Renal etiology multiple organ failure. Medical search. Frequent questions

A 26-year-old Caucasian woman presented with acute renal failure as an initial manifestation of sarcoidosis. (medscape.com)
Some studies have shown that granulomatous tubulointerstitial nephritis is associated with acute renal failure and may lead to hemodialysis. (medscape.com)
Acute renal failure (ARF) is characterized by a rapid onset of renal insufficiency/failure, reduction in glomerular filtration rate and renal plasma flow, and the clinical and biochemical aftermath of the excretory failure. (vin.com)
Acute renal failure is a tenuously reversible state, which must be diagnosed quickly and aggressively treated. (vin.com)
Acute renal failure is frequently a complication of other surgical or medical diseases and must be recognized within the clinical features of these associated disorders. (vin.com)
Quantitation of urine output may not sufficiently differentiate acute renal failure from polyuric forms of chronic renal failure. (vin.com)
23-25 Likewise, acute renal failure and hepatorenal syndrome are important complications of ALF and are primarily a result of the hemodynamic alterations in ALF. (emdocs.net)
Acute renal failure (ARF) is a prominent feature of leptospirosis. (tmu.edu.tw)
He was admitted to the surgical intensive care unit of the CHRU La Cavale Blanche of Brest on 12 September, 2015 for decompensated diabetic ketoacidosis, acute renal failure and hemolytic anemia. (scirp.org)

For the others, the most common non-renal causes are multiple organ dysfunc-tion syndrome (MODS) that occurs as a result of cardiac insufficiency, hepatic in-sufficiency or after surgeries, as well as in hemato-oncologic diseases. (signavitae.com)
The information recorded included demographics, preexisting comorbidities, which were summarized by using the Charlson index ( 3 ) and McCabe classification ( 4 ), and clinical manifestations described by organ system (e.g., cardio-circulatory, cerebral, respiratory, renal, and hepatic). (cdc.gov)
Acute liver failure is the clinical manifestation of sudden and severe hepatic injury, and has a variety of underlying etiologies, including drug toxicity, viral infections, autoimmune and genetic disorders, thrombosis, malignancy, heat injury, and ischemia. (emdocs.net)
Hepatic failure occurs when the liver loses the ability to regenerate or repair, so that decompensation occurs. (patient.info)
There are many causes of hepatic failure and the following represent just a few. (patient.info)
This occurs with intentional overdose or with therapeutic dosing in patients with reduced clearance of colchicine due to pre-existing renal or hepatic impairment. (biomedcentral.com)
The potential of new extracorporeal molecular technologies allows their successful use in severe cardiac and respiratory failure, acute kidney injury and hepatic dysfunction and in complex therapy for severe infections and sepsis and extreme metabolic violations. (oaepublish.com)

Failure to respond to corticosteroids or relapse after withdrawal may be associated with worsening of renal failure, requiring dialysis and even kidney transplantation. (medscape.com)
Replacment of Renal Function by Dialysis, ed. 2. (signavitae.com)
The newly introduced ADVanced Organ Support (ADVOS) system (previously known as the Hepa Wash procedure), combining liver and renal support, based on albumin dialysis, has been shown to improve dysfunction of the liver and kidney and the circulatory system and survival in an animal model of acute liver failure [ 10 ]. (springeropen.com)
Renal dialysis may be required to help with kidney failure or fluid overload. (mountelizabeth.com.sg)
He owns the absolute priority in the development and the introduction into the clinical practice of Russian clinics of modern methods of correction and maintaining homeostasis, including albumin dialysis, combined plasma filtration and adsorption, selective hemoperfusion, etc. at extremely severe contingent of patients of different age groups having multiple organ failure and septic complications after cardiac surgery. (oaepublish.com)
For patients on renal dialysis, an additional dose of [HA570 trade name] is recommended after each dialysis. (who.int)

Oliguria and less frequently anuria were at one time considered signatures of ARF and discriminators for chronic renal failure. (vin.com)
Many animals with compensated and asymptomatic chronic renal insufficiency sustain subtle insults (e.g., fever, concomitant disease, vomiting, diarrhea, congestive heart failure, drug administration), which precipitate a seemingly acute uremic crisis (designated A acute-on-chronic@ renal failure). (vin.com)
Because of the abrupt onset of uremia, patients are usually well fleshed, have glossy well groomed hair coats, and pink mucous membranes in contrast to animals with chronic diseases and chronic renal failure. (vin.com)
However, acute uremia is frequently superimposed on other diseases or chronic renal failure, and the physical manifestations of these primary conditions may dominate the clinical presentation and mask the features of ARF. (vin.com)
The results show that the most common renal causes to perform haemodialysis are: haemolytic uremic syndrome (HUS), chronic renal failure, nephrotic syndrome and congenital bilateral nephrolithiasis. (signavitae.com)
He has a history of red cell and platelet transfusion dependent myelofibrosis, iron overload due to multiple red cell transfusion, chronic renal failure, ischemic heart disease, left ventricular systolic dysfunction, cerebrovascular disease, peripheral vascular disease, hypertension, and hyperlipidemia. (biomedcentral.com)

Chronic fatigue syndrome (CFS) is defined by symptoms and disability, has no confirmatory physical signs or characteristic laboratory abnormalities, and the etiology and pathophysiology remain unknown. (biomedcentral.com)

Sepsis and Septic Shock Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. (msdmanuals.com)
Renal anomalies, which may include unilateral agenesis of the kidney, ectopic kidneys, horseshoe kidney, and crossed-fused ectopia, occur in 30% of patients with RMKH syndrome. (medscape.com)
Extracorporeal blood purification is becoming increasingly important in intensive therapy for multiple organ dysfunction syndrome (MODS) and sepsis, considering all of their pathophysiological aspects. (oaepublish.com)
[ 1 ] up to 90% of the AKI in this group are part of a multiple organ dysfunction syndrome (MODS), indicating the severity of the patients' condition. (oaepublish.com)
There is a continuum of clinical manifestations from SIRS to sepsis to severe sepsis to septic shock to Multiple Organ Dysfunction Syndrome (MODS). (atsu.edu)
Hence, we set out to address the aetiology and outcome of this still highly fatal syndrome. (rcpe.ac.uk)

Liposomal formulations have been found to have less renal toxicity than deoxycholate, and fewer infusion-related reactions. (wikipedia.org)
29,30 Likewise, direct renal toxicity may be seen, as is in the case of acetaminophen toxicity or amanita poisoning. (emdocs.net)
We report a case of acute pancreatitis without other organ toxicity related to recent commencement of colchicine for acute gout, occurring in an elderly male with pre-existing renal impairment. (biomedcentral.com)

Overview of Plasma Cell Disorders Plasma cell disorders are a diverse group of disorders of unknown etiology characterized by Disproportionate proliferation of a single clone of B cells Presence of a structurally and electrophoretically. (merckmanuals.com)
On 31 December 2019, the WHO China Country Office was informed of cases of pneumonia [of] unknown etiology (unknown cause) detected in Wuhan City, Hubei Province of China. (thrivetimeshow.com)
From 31 December 2019 through 3 January 2020, a total of 44 case-patients with pneumonia of unknown etiology were reported to WHO by the national authorities in China. (thrivetimeshow.com)

1) Colchicine should be used with care in elderly patients or patients with impaired renal function. (biomedcentral.com)

A history of weight loss, polyuria, polydipsia, nocturia or isosthenuria, or laboratory evidence of preexisting renal insufficiency suggest an underlying chronic condition. (vin.com)
Common manifestations include lytic lesions in bones that cause pain and/or fractures, renal insufficiency, hypercalcemia, anemia, and recurrent infections. (merckmanuals.com)
The small number of patients with renal insufficiency not requiring RRT had a more favorable hospital outcome and mortality, but long-term survival remained poor. (biomedcentral.com)

[ 4 ] Renal manifestations of sarcoidosis include changes in calcium metabolism, nephrocalcinosis and nephrolithiasis. (medscape.com)
Systemic scleroderma is a rare disease in which visceral manifestations occur, particularly peripheral vascular, digestive, cardiopulmonary and renal. (scirp.org)

Leptospirosis represented 31% of all cause etiology and 88% of infectious causes. (vin.com)
Cases were classified as excluded based on confirmed etiology other than leptospirosis or negative paired serologic test. (tmu.edu.tw)

The disease affects virtually all mammals and has a broad range of clinical effects, from mild, subclinical infection to multiple-organ failure and death. (merckvetmanual.com)
Status of SARS-CoV-2 infection in patients on renal replacement therapy. (revistanefrologia.com)
The major cause of MOF is sepsis, which has been recently redefined by the European Society of Intensive Care Medicine as a "life-threatening organ dysfunction due to a dysregulated host response to infection" [ 11 ]. (springeropen.com)
As with any infectious organism, an infection can affect multiple organs. (mountelizabeth.com.sg)
[ 1 ] Globally, the incidence varies and viral infection accounts for the majority of cases of liver failure. (patient.info)
Infection rates among lung transplant recipients appear to be higher than those encountered in other solid organ transplant populations, likely related to the unique exposure of the lung allograft to the external environment and to the greater magnitude of immunosuppression employed 1 , 2 . (ersjournals.com)
Although passive transfer of occult infection with the transplanted organ is an additional concern, the presence of organisms on Gram stain of donor bronchial washings is not predictive of subsequent pneumonia in the recipient 4 . (ersjournals.com)
Conclusion The aetiology of ARDS in tropical medical setting is infection related. (rcpe.ac.uk)

Standard definitions were used for organ system failures and severe sepsis and septic shock ( 5 ). (cdc.gov)
Hyperdynamic circulation with multiple organ failure may mimic septic shock. (patient.info)

Treatment of children with complications of cancer therapy and multiple organ failure. (signavitae.com)
The present clinical case is that of a man with the renal complications of scleroderma and the difficulties of the treatment even in the developed countries like France. (scirp.org)
It is the second leading cause of maternal mortality worldwide 7 , 8 and may also lead to other serious maternal complications, including stroke, eclampsia, and organ failure. (aafp.org)

In Multiple Sclerosis Interferonb has been used as a first line treatment regimen for the past 15 years and many patients have shown therapeutic benefit and continue to do so from this 'natural' immune modulator. (hrb.ie)
There were 18 (52.9%) primary nephrologic pa-tients, while 16 (41.05%) were patients whose renal failure was caused by other etiology. (signavitae.com)
Patients on renal replacement therapy (RRT) have not been unaware of this situation and due to their characteristics they are especially vulnerable. (revistanefrologia.com)
Multiple organ failure (MOF) is a major contributor to the mortality of patients with sepsis in the intensive care unit (ICU) [ 1 ]. (springeropen.com)
As proposed by Ronco and Bellomo, single-organ support may be a simplistic view for the management of ICU patients, suggesting that multi-organ support therapy should represent the most logical future conceptual and practical evolution to achieve the goal of extracorporeal blood purification [ 9 ]. (springeropen.com)
2 , 3 Although pregnant women can have other hypertensive conditions along with preeclampsia, preeclampsia is defined as new-onset hypertension (or, in patients with existing hypertension, worsening hypertension) occurring after 20 weeks of gestation, combined with either new-onset proteinuria (excess protein in the urine) or other signs or symptoms involving multiple organ systems. (aafp.org)
4 Patients with severe injuries that develop rhabdomyolysis-induced renal failure have a mortality of approximately 20% but is higher if multiple organ dysfunction is present. (wfsahq.org)
Methotrexate elimination is reduced in patients with impaired renal functions, ascites, or pleural effusions. (nih.gov)
If approved by the U.S. FDA, it may provide a new option for patients with severe CKD and sodium- or volume-dependent comorbidities who may otherwise require renal replacement therapy for acidosis control. (mhmedical.com)
Renal replacement therapy (RRT) is a routine method for intensive care patients with acute kidney injury (AKI). (oaepublish.com)
The highest mortality rates (38% and 45%, respectively) were noted for patients with a SIRS score of 4 on day 2 or 3, suggesting the importance of failure of early resuscitation to ameliorate the proinflammatory response in critically ill patients. (jamanetwork.com)
9 Patients with heart failure, chronic kidney disease (CKD) with volume overload state and chronic obstructive pulmonary disease were excluded. (rcpe.ac.uk)
We gathered outcome data on patients who had severe renal dysfunction on transfer to our regional weaning center (RWC) for attempted weaning from prolonged mechanical ventilation (PMV). (biomedcentral.com)
RRT was withheld at patient/family request in five patients with progressive renal failure. (biomedcentral.com)
None of the 50 patients who received RRT recovered renal function during treatment at our RWC. (biomedcentral.com)
The five patients in whom RRT was withheld were predominantly in progressive multisystem organ failure, and were unlikely to have survived regardless of RRT. (biomedcentral.com)
In this study, we gathered outcome data on the cohort of ventilator-dependent patients with severe renal dysfunction on admission to our RWC in order to further elucidate the impact of renal dysfunction on weaning from PMV. (biomedcentral.com)

The clinical presentation and outcome of ARF varies depending on the cause, severity, previous therapy, and associated diseases predisposing the renal injury. (vin.com)
The manifestation, timing, and severity of ALF's clinical features vary according to its underlying etiology, and a high index of suspicion is required to make an early diagnosis. (emdocs.net)
The severity of the different organ dysfunctions in sepsis and its correlation to mortality can be estimated by the sepsis-related organ failure assessment (SOFA) score, which covers six different organ systems (and parameters) graded from 0 (no dysfunction) to 4 (severe dysfunction/failure), including the liver (bilirubin) and the kidney (creatinine) [ 12 ]. (springeropen.com)
The clinical presentation of rhabdomyolysis varies depending on the aetiology and severity. (wfsahq.org)
The results of treatment, particularly in children, considering their anatomical and physiological features, are related to the severity and progression of organ failure, the indications that are found, the choice of method, and the timely initiation of blood purification. (oaepublish.com)

The ADVOS procedure showed a promising safety and efficacy profile and improved survival in a sepsis-like animal model with dysfunction of multiple organs. (springeropen.com)
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference, Definitions for sepsis and organ failure, and guidelines for the use of innovative therapies in sepsis. (jamanetwork.com)

Although acute liver failure (ALF) is a rare clinical presentation in the ED, it carries a high mortality, morbidity, and resource cost. (emdocs.net)

An abdominal ultrasound demonstrated normal liver texture, oedematous pancreas, and multiple small incidental calculi within a normal walled gallbladder, no hepatobiliary ductal dilatation or pericholecystic fluid, normal pancreatic duct, enlarged spleen and multiple bilateral renal cysts without hydronephrosis. (biomedcentral.com)

This case describes a patient presenting as acute myocardial infarction (AMI) with cardiogenic shock and acute hypoxic respiratory failure secondary to COVID-19 complicated by acute embolic stroke. (cardiologyresearchjournal.com)
As such, we present a patient presenting as acute myocardial infarction with cardiogenic shock, undergoing revascularization and developing acute hypoxic respiratory failure secondary to COVID-19 resulting in multiorgan failure. (cardiologyresearchjournal.com)
Influenza, one of the most common infectious diseases, is a highly contagious airborne disease that occurs in seasonal epidemics and manifests as an acute febrile illness with variable degrees of systemic symptoms, ranging from mild fatigue to respiratory failure and death. (medscape.com)

The excretory failure is identified by rapid (hours to days) increases in BUN, serum creatinine and phosphate, and variable hyperkalemia and metabolic acidosis. (vin.com)

An amelioration of major organ functions (heart and lung) combined with removal of markers for kidney and liver function was observed. (springeropen.com)

Cardiac rehabilitation programs are designed to improve heart health through activities such as monitored exercise, and they are often recommended for individuals who have heart failure or who have had a heart attack. (healthyplace.com)
Discontinuing drugs that worsen and heart failure have been reported to be associated fatigue could assist, including cardiac medicines, benzowith larger rates of depression, though this is controdiazepines, sure antidepressants or opioids, if pain is versial. (ehd.org)
Within these 28 cases, 15 died of sudden cardiac arrest and 13 of acute heart failure. (nature.com)
Heart failure and sudden cardiac arrest occur at various ages with inter- and intrafamilial phenotypic variability, and presentation can include progressive neurological disease. (nature.com)

While there are more than 40 definitions of acute liver failure in use, many of themodern definitions recognize the distinct disease phenotypes and seek to quantify the interval between the onset of symptoms and the development of encephalopathy. (emdocs.net)
There are multiple possible onset patterns for post-COVID conditions that have been identified, which further exemplifies their heterogeneity. (cdc.gov)
Important clinical conditions associated with increased risk include a history of eclampsia or preeclampsia (particularly early-onset preeclampsia), previous adverse pregnancy outcome, maternal comorbid conditions (type 1 or 2 diabetes, gestational diabetes, chronic hypertension, renal disease, and autoimmune diseases), and multifetal gestation. (aafp.org)
The onset and etiologies of respiratory and renal failures were assessed and recorded based on the transfer records. (biomedcentral.com)

Since May 2015 Mr. MG has been presenting with recurrent pleural effusions and lower extremity edema without initial etiology identified. (scirp.org)

However, anti-TNF-α therapies have limitations, including known adverse safety risk, loss of therapeutic efficacy due to drug resistance, and lack of efficacy in numerous autoimmune diseases, including multiple sclerosis. (frontiersin.org)
Loss of immune tolerance to autoantigens associated with a specific organ results in the activation of organ-specific T and B cells that in turn cause organ-specific inflammation and the development of autoimmune diseases such as multiple sclerosis (MS) ( 5 ), rheumatoid arthritis (RA) ( 6 ), psoriasis ( 7 ), and type 1 diabetes (T1D) ( 8 ). (frontiersin.org)

Multiple myeloma is a cancer of plasma cells that produce monoclonal immunoglobulin and invade and destroy adjacent bone tissue. (merckmanuals.com)
Key Statistics About Multiple Myeloma. (merckmanuals.com)

Sarcoidosis is a systemic disease caused by noncaseating granulomas in multiple organs. (medscape.com)
The objective of this presentation is to guide any practitioner towards diagnosis of renal crisis in the face of sudden multiple organ failure resulting from progressive systemic sclerosis. (scirp.org)
The etiology mentioned was progressive systemic sclerosis. (scirp.org)

Conversely, in the USA and much of Europe, the incidence of virally associated liver failure has declined substantially, with most cases now arising from drug-induced liver injury, frequently from acetaminophen or idiosyncratic drug reactions. (emdocs.net)
In the present work, the safety and efficacy of a recently developed ADVanced Organ Support (ADVOS) system in a newly developed large animal two-hit model of liver failure combined with endotoxemia were tested. (springeropen.com)
In severe cases, both types of hepatitis may result in liver failure. (mountelizabeth.com.sg)
You may find the Liver Failure article more useful, or one of our other health articles . (patient.info)
What is liver failure? (patient.info)
If this occurs rapidly in a patient with no previous liver disease it is termed acute liver failure. (patient.info)
If the person has previously had liver disease it is termed acute on chronic liver failure. (patient.info)
How common is liver failure? (patient.info)
In the Western world, acute liver failure is estimated to affect fewer than 6.5 people per million population per year. (patient.info)

[3] The disease can quickly progress to multi-organ system failure leading to shock followed by death. (statpearls.com)
Acute pancreatitis has rarely been reported, and only in association with severe colchicine overdose accompanied by multi-organ failure. (biomedcentral.com)

During each of the influenza pandemics of the 20th century, secondary bacterial pneumonia was a frequent cause of illness and death and S. pneumoniae was reported as the most common etiology. (cdc.gov)
26-28 Initially renal injury is prerenal in etiology secondary to hypovolemia, but acute tubular necrosis rapidly develops due to ongoing ischemia of renal tubules. (emdocs.net)
Peripheral tolerance occurs in the secondary lymphoid organs (e.g. spleen, lymph nodes, and mucosal/gut associated lymphoid tissues) and peripheral tissues. (frontiersin.org)

In this study we prospectively studied the aetiology of ARDS and its short-term outcome. (rcpe.ac.uk)
Moreover, the aetiology of ARDS might be different compared to other regions of the world. (rcpe.ac.uk)

Across the developing world, the underlying etiology is primarily viral, with hepatitis B and E infections recognized as leading causes in many countries. (emdocs.net)
His pneumonia was felt to be viral in etiology and he was not placed on any antibiotics. (hawaii.edu)

After endotoxemia, the ADVOS procedure stabilized cardiovascular, respiratory, and renal parameters and eliminated surrogate markers as bilirubin [2.3 (IQR 2.3-3.0) vs. 5.5 (IQR 4.6-5.6) mg/dl, p = 0.001] and creatinine [1.4 (IQR 1.1-1.7) vs. 2.3 (IQR 2.1-3.1) mg/dl, p = 0.01]. (springeropen.com)
Orthostatic hypotension (OH) and supine hypertension (SH) are two cardiovascular symptoms of autonomic failure that frequently coexist in the same patient. (journalca.com)
Consensus statement on the definition of neurogenic supine hypertension in cardiovascular autonomic failure by the American Autonomic Society (AAS) and the European Federation of Autonomic Societies (EFAS). (journalca.com)

In the present case, the management of this disease required a high dose of corticosteroid therapy and extra-renal purification. (scirp.org)
Multiple organ support therapy is the aim of introducing and applying blood purification today. (oaepublish.com)

Renal involvement is an uncommon feature of sarcoidosis and it is essential to establish a fast and correct diagnosis because early therapy avoids progression to terminal renal failure. (medscape.com)
Failure to initiate therapy may result in irreversible parenchymal damage or death. (vin.com)
In the intensive care unit (ICU) setting, the combination of mechanical ventilation and renal replacement therapy (RRT) has been associated with prolonged length of hospital stay, high cost of care and poor outcome. (biomedcentral.com)

Central tolerance occurs during lymphocyte development in the primary lymphoid organs (i.e. thymus and bone marrow), where T or B cell clones that recognize autoantigens with high-affinity are deleted. (frontiersin.org)

For these reasons, we report three observations, whose etiologies, clinical presentation, and treatment are different, namely diabetes, multiple system atrophy type C (MSA) and Parkinson's disease. (journalca.com)

The etiology of ARF varies geographically as differences in infectious causes will differ regionally as will therapeutic practices that might predispose to acute renal injury. (vin.com)

1 It has multiple subtypes and potentially serious, even fatal health outcomes. (aafp.org)

Shock is a state of organ hypoperfusion with resultant cellular dysfunction and death. (msdmanuals.com)

Indeed, MOF results from an "altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention" [ 8 ]. (springeropen.com)

Anatomy5

Organisms2

Diseases31

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Phenomena and Processes2

Information Science4

Health Care18

Acute renal f9

Hepatic7

Dialysis6

Chronic renal f6

Pathophysiology1

Syndrome6

Toxicity3

Unknown etiology3

Impaired renal function1

Insufficiency3

Manifestations2

Leptospirosis2

Infection8

Septic2

Complications3

Patients17

Severity5

Sepsis2

Mortality1

Enlarged spleen1

Respiratory failure3

Acidosis1

Kidney1

Cardiac4

Onset4

Pleural effusions1

Autoimmune diseases2

Myeloma2

Systemic3

Liver9

Multi-organ2

Secondary3

ARDS2

Viral2

Cardiovascular3

Purification2

Therapy3

Occurs1

Etiologies1

Varies1

Outcomes1

Hypoperfusion1

Altered organ function1