• Clinical trials of off-pump coronary artery bypass grafting (CABG) have largely excluded patients with CKD. (usuhs.edu)
  • Using a nonrandomized cohort of 742,909 non-emergent, isolated CABG cases, which included 158,561 off-pump cases, in the Society of Thoracic Surgery Database from 2004 through 2009, we evaluated the association between pump status (off-pump versus on-pump) and in-hospital death or incident renal replacement therapy (RRT) across strata of preoperative renal function. (usuhs.edu)
  • Patients who received on-pump and off-pump CABG had similar mean age and distribution of preoperative estimated GFR (eGFR). (usuhs.edu)
  • In a propensity-weighted analysis, off-pump CABG was associated with a reduction in the composite in-hospital death or RRT, with patients having lower preoperative renal function exhibiting greater benefit, on average. (usuhs.edu)
  • In summary, these data suggest that patients with CKD experience less death or incident RRT when treated with off-pump compared with on-pump CABG. (usuhs.edu)
  • We aimed to evaluate the occurrence of adverse renal outcomes, in diabetic patients, between on-pump (CPB) and off-pump (OPCAB) coronary artery bypass graft (CABG). (strath.ac.uk)
  • CABG surgery involves bypassing the blocked coronary arteries with a blood vessel graft. (apollohospitals.com)
  • There is a paucity of direct data on the incidence and predictors of intracranial bleeding (ICB) after coronary artery bypass graft surgery (CABG). (frontiersin.org)
  • The predictors of ICB after CABG were age ≥ 75 years, hypertension, pre-existing dementia, history of ischemic stroke or transient ischemic attack, and end-stage renal disease. (frontiersin.org)
  • Coronary artery bypass graft surgery (CABG) offers a better survival rate than percutaneous coronary intervention (PCI) and is therefore the treatment of choice in patients with severe coronary artery disease (CAD). (frontiersin.org)
  • We previously reported that there was no significant difference at 30 days or at 1 year in the rate of the composite outcome of death , stroke , myocardial infarction , or renal failure between patients who underwent coronary- artery bypass grafting (CABG) performed with a beating- heart technique (off-pump) and those who underwent CABG performed with cardiopulmonary bypass (on-pump). (bvsalud.org)
  • A total of 4752 patients (from 19 countries) who had coronary artery disease were randomly assigned to undergo off-pump or on-pump CABG. (bvsalud.org)
  • For this report , we analyzed a composite outcome of death , stroke , myocardial infarction , renal failure , or repeat coronary revascularization (either CABG or percutaneous coronary intervention ). (bvsalud.org)
  • Coronary artery bypass grafting (CABG) is a common procedure, but one with significant costs and complexities. (getinge.com)
  • For more than 50 years, coronary artery bypass graft (CABG) surgery has been the standard of care for revascularization of patients with coronary artery disease. (getinge.com)
  • Prediction scoring systems for coronary artery bypass grafting (CABG) patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) have not yet been reported. (biomedcentral.com)
  • We developed the pRedicting mortality in patients undergoing veno-arterial Extracorporeal MEMBrane oxygenation after coronary artEry bypass gRafting (REMEMBER) score, which might help the clinicians to select patients that would benefit from VA-ECMO after CABG. (biomedcentral.com)
  • Two large trials presented at the American College of Cardiology meeting in San Francisco and published simultaneously in the New England Journal of Medicine provide important new information about the ongoing debate over whether CABG should be performed with or without cardiopulmonary bypass. (cardiobrief.org)
  • Previous 30-days results from CORONARY (CABG Off or On Pump Revascularization Study), which randomized 4,752 patients to on-pump or off-pump CABG, showed no significant difference in the primary outcome (death, MI, stroke, or new renal failure requiring dialysis) between the two groups. (cardiobrief.org)
  • In the GOCABE (German Off-Pump Coronary Artery Bypass Grafting in Elderly Patients) study, 2,539 patients 75 years of age or older were randomized to on-pump or off-pump CABG. (cardiobrief.org)
  • The authors write that their trial "does not support the assumption that off-pump CABG can improve the early outcome in high-risk patients. (cardiobrief.org)
  • The demand for improved anesthesia during off-pump coronary artery bypass grafting (OP-CABG) is continually increasing. (clinicaltdd.com)
  • Coronary angiogram showed coronary artery diseases (3-vessel diseases) and CABG was planned. (accjournal.org)
  • However, lower extremity angiogram showed stenosis of both common iliac arteries and stent implantation of both iliac arteries were done before CABG. (accjournal.org)
  • He underwent CABG and IABP was inserted for weaning from cardiopulmonary bypass. (accjournal.org)
  • Coronary artery bypass grafting (CABG) involves bypassing native coronary arteries that have high-grade stenosis or occlusion not amenable to angioplasty with stent insertion. (msdmanuals.com)
  • A number of patients undergo coronary artery bypass graft (CABG) surgery as treatment for ischaemic heart disease. (druglib.com)
  • OPCABG avoid CPB to the human body's internal environment disrupt a series of complications, compared with the pump coronary artery bypass grafting (conventional CABG, CCABG), OPCABG also reduce the body's inflammatory response, and significantly reduce oxygen free radical production and myocardial injury [ 2 - 4 ]. (biomedres.info)
  • Meloxicam is contraindicated in treatment of perioperative pain after coronary artery bypass surgery (CABG). (medicines.org.uk)
  • The use of coronary artery bypass grafting (CABG) supported by cardiopulmonary bypass (CPB) evolved into a practical technique during the late 1960s and has since then been the state of the art with low morbidity and mortality. (medicus.ru)
  • Adding to the breadth of our experience and expertise we successfully completed on-time and within budget constraints an entire CABG (Coronary Artery Bypass Grafting) program. (ihcresearch.com)
  • Coronary artery bypass grafting (CABG) is performed for patients with coronary artery disease (CAD) to improve quality of life and reduce cardiac-related mortality. (medscape.com)
  • Despite these initial positive results, the European Coronary Surgery Study conducted in the 1970s indicated that the significant improvement in 5-year survival rates with CABG was not apparent in the subsequent 5 years. (medscape.com)
  • CABG may be performed as an emergency procedure in the context of an ST-segment elevation MI (STEMI) in cases where it has not been possible to perform percutaneous coronary intervention (PCI) or where PCI has failed and there is persistent pain and ischemia threatening a significant area of myocardium despite medical therapy. (medscape.com)
  • The authors hypothesized that, compared with normothermia, hypothermic CPB would result in superior neurologic and neurocognitive function after coronary artery bypass graft surgery. (asahq.org)
  • Three hundred patients undergoing elective coronary artery bypass graft surgery were prospectively enrolled and randomly assigned to either normothermic (35.5-36.5 degrees C) or hypothermic (28-30 degrees C) CPB. (asahq.org)
  • Methods This study was a post hoc analysis of the Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Patient Undergoing Coronary Artery Bypass Graft Surgery trial involving adult patients undergoing coronary artery bypass graft. (bmj.com)
  • We evaluated perioperative kidney injury and function in patients treated with conventional extracorporeal circulation (CECC), minimized extracorporeal circulation (MECC), and off-pump coronary artery bypass grafting (OPCAB). (nih.gov)
  • Conclusion During coronary artery bypass grafting, CECC temporarily induces more tubular injury than MECC or OPCAB. (nih.gov)
  • The aim of our study was to compare early and long-term outcome of patients undergoing either on-pump or off-pump coronary artery bypass grafting with special focus on impairment of renal function. (uni-koeln.de)
  • Five hundred ninety-three consecutive patients undergoing coronary artery bypass grafting were retrospectively analyzed. (uni-koeln.de)
  • Coronary artery bypass grafting: are risk models developed from on-pump surgery valid for off-pump surgery? (pacecpmregistry.org)
  • Importantly, the majority of these cases have been performed as off-pump coronary artery bypass (OPCABs) on a beating heart, allowing for the immediate physiologic evaluation of grafting. (medscape.com)
  • The fluorescent technique illuminates in the arterial phase both the native TVECA and the graft to visualize flow down both vessels, competitive flow interactions, whether grafting has compromised the native coronary flow and the anastomosis integrity (Figure 1). (medscape.com)
  • Using a specific data acquisition protocol, this imaging technology and software compares regional myocardial perfusion before and after grafting, and quantifies the difference, if any, that results from the bypass graft (Figure 3). (medscape.com)
  • Traditional coronary artery bypass grafting involves thoracotomy via a midline (median) sternotomy. (msdmanuals.com)
  • Unmeasured confounders in observational studies comparing bilateral versus single internal thoracic artery for coronary artery bypass grafting: a meta-analysis. (jamanetwork.com)
  • Arterial revascularization in primary coronary artery bypass grafting: direct comparison of 4 strategies-results of the Stand-in-Y Mammary Study. (jamanetwork.com)
  • The purpose of this study is to evaluate the anesthesia methods by observing hemodynamic changes, oxygen supply and demand balance in order to provide the reference for the Off-Pump Coronary Artery Bypass Grafting (OPCABG) anesthesia management level during OPCABG. (biomedres.info)
  • first reported Off-Pump Coronary Artery Bypass Grafting (OPCABG), with the growing maturity of surgical techniques, anesthesia management level continues to improve, as well as surgical instruments, advanced cardiac fixation devices (such as Octopus). (biomedres.info)
  • Twenty patients undergoing coronary artery bypass grafting were included. (peertechzpublications.com)
  • A 52 year male undergoing elective coronary artery bypass grafting was incidentally discovered to have a large soft tissue mass of variable consistency with cartilaginous elements arising from the right costal margin and adjoining ribs by a broad attachment and protruding into right pleural cavity. (biomedcentral.com)
  • A wide excision of the mass with the adjoining muscle and periosteum along with quadruple coronary artery bypass grafting was done. (biomedcentral.com)
  • This report is unusual on account of a) being the first reported case in world literature of concomitant excision of chondrosarcoma and coronary artery bypass grafting and b) the conservative management of the incidentally discovered chondrosarcoma by wide excision rather than chest wall resection with no local recurrence to date. (biomedcentral.com)
  • A 52 year old male smoker undergoing coronary artery bypass grafting for three vessel coronary artery disease and moderately impaired left ventricular function was felt to have a mass arising from the under surface of right costal margin adjacent to right lower sternal margin while sternopericardial ligament was being broken off by finger dissection prior to sternotomy. (biomedcentral.com)
  • Percutaneous Coronary Interventions (PCI) Percutaneous coronary interventions (PCI) include percutaneous transluminal coronary angioplasty (PTCA) with or without stent insertion. (msdmanuals.com)
  • One large clinical program assessed patients undergoing percutaneous coronary intervention, and in patients with or at risk for heparin-induced thrombocytopenia and thrombosis syndrome (HIT/HITTS) undergoing PCI. (ihcresearch.com)
  • A study of 21,848 non-emergent, high-risk patients who underwent percutaneous coronary intervention (PCI) with percutaneous ventricular assist devices (PVADs), including Impella® heart pumps, demonstrates the PVAD patients had a lower rate of mortality and complications than patients who underwent PCI with intra-aortic balloon pumps (IABPs). (heartrecovery.com)
  • An intra-aortic balloon pump was placed due to hemodynamic instability following percutaneous coronary intervention. (journalmc.org)
  • The left internal mammary artery is typically used as a pedicled graft to the left anterior descending coronary artery. (msdmanuals.com)
  • Occasionally, the right internal mammary artery or radial artery from the nondominant arm can be used. (msdmanuals.com)
  • The material which is grafted to the heart in order to be circumvented the narrowing or blockage of the coronary artery is either the great saphenous vein (vena safena magna) which is taken from the lower limb of the patient or internal mammary artery (arteria mammaria interna) which is located in the thoracic cavity. (myhealthlegacy.com)
  • Methods Blood and urine samples, collected at baseline and up to 72 hours after surgery from patients of the HEPCON trial (DRKS00007580, 120 patients randomized for heparin management and for surgical technique), were analyzed for differences in renal injury and function. (nih.gov)
  • However, late changes of renal function parameters occur irrespective of extracorporeal perfusion mode and even in off-pump surgery. (nih.gov)
  • The decision to go for an off-pump or on-pump surgery completely lies with your surgeon. (apollohospitals.com)
  • At the ACC news conference, Mark Davies said that "these trials may temper our enthusiasm for off-pump surgery. (cardiobrief.org)
  • The authors present a patient with coronary artery disease undergoing off-pump coronary artery bypass surgery after the institutional protocol of two COVID-19 reverse-transcriptase polymerase chain reaction tests reported negative. (perfusion.com)
  • Radial artery versus saphenous vein as the second conduit for coronary artery bypass surgery: a meta-analysis. (jamanetwork.com)
  • Radial-artery or saphenous-vein grafts in coronary-artery bypass surgery. (jamanetwork.com)
  • The purpose of this study is to determine whether Glyceryl Trinitrate (GTN) reduces injury to the heart during heart-lung bypass surgery in combination with the newer technique of remote ischaemic preconditioning (RIPC). (druglib.com)
  • The study is known as CiPRICS (Ciclosporin to Protect Renal function In Cardiac Surgery) and is a double-blind, randomized and placebo-controlled clinical phase II study to include a total of 150 patients. (abliva.com)
  • The patients will be treated with CicloMulsion® in connection with coronary artery bypass surgery at the Clinic for Cardiothoracic Surgery at Skåne University Hospital in Lund, Sweden. (abliva.com)
  • We know that patients who suffer from a transient reduction in renal function in connection with heart surgery have a poorer prognosis, and there are currently no preventive treatments available. (abliva.com)
  • What's unique about our study is that we'll focus specifically on patients with the highest risk of kidney injury and will monitor renal function very closely in the days following surgery. (abliva.com)
  • During cardiac surgery, the heart is usually stopped during surgery to enable procedures such as heart valve repair or coronary artery bypass grafts. (abliva.com)
  • This applies particularly to patients where renal function is already compromised prior to surgery and where the risk of complications is considered the greatest. (abliva.com)
  • Consequently, there has been a growing interest in safer alternatives to CCAB including off-pump beating heart bypass surgery (OPCAB). (ecrjournal.com)
  • Since the introduction of OPCAB for coronary artery disease numerous studies were published to evaluate the impact of OPCAB surgery compared with CCAB. (ecrjournal.com)
  • Based on haemodynamic and functional considerations it is less reasonable to identify coronary left main stenosis as a special risk factor for OPCAB surgery. (ecrjournal.com)
  • Beating heart coronary surgery supported by an axial blood flow pump / Медикус. (medicus.ru)
  • With a medical focus on cardiac surgery, cardiology, anesthesiology and intensive care, we offer further comprehensive diagnostic measures and non-surgical therapies for all heart diseases, for example TAVI (minimally invasive heart valve replacement), defibrillator and pacemaker implantations, interventional mitral valve therapy (MitraClip), electrophysiological examinations (EPU), ablation procedures, highly complex coronary interventions. (myacare.com)
  • [ 3 ] Denault et al described difficult (or pharmacologically assisted) separation from bypass (DSB) as the requirement for at least both vasoactive and inotropic agents from the end of CPB until the end of surgery. (medscape.com)
  • [ 3 ] Both hemodynamic instability and sympathetic activity during surgery are harmful for renal function. (medscape.com)
  • In addition, there has been no systematic review that comprehensively focuses on the potential renal effect of dexmedetomidine in adult cardiac surgery. (medscape.com)
  • However, patients in the off-pump group required more repeat revascularization procedures, though they had lower rates of bleeding, acute kidney injury, and respiratory complications. (cardiobrief.org)
  • The primary endpoint was the composite of death, stroke, MI, repeat revascularization, or new renal-replacement therapy at 30 days and one year. (cardiobrief.org)
  • Patients who will experience little benefit from coronary revascularization are also excluded. (medscape.com)
  • In the presence of ongoing ischemia or left ventricular dysfunction, pre-operative IABP counterpulsation therapy can provide myocardial protection by reducing perioperative myocardial ischemia, stabilizing hemodynamics and improving coronary perfusion. (getinge.com)
  • Post-CPB bleeding is a common problem caused by various factors, including hemodilution, heparin use, platelet dysfunction due to exposure to the bypass pump, disseminated intravascular coagulation, and induced hypothermia. (msdmanuals.com)
  • What is further evident in the literature is that decompensated liver disease increases the risk of postoperative complications (eg, acute hepatic failure, infections including sepsis, bleeding, poor wound healing, and renal dysfunction). (medscape.com)
  • It also reduces the risk of postoperative brain damage, intraoperative blood loss, renal dysfunction and postoperative cognitive dysfunction [ 5 ]. (biomedres.info)
  • 0.1 μg/kg/min), or an intra-aortic balloon pump (IABP). (biomedcentral.com)
  • The intra-aortic balloon pump (IABP) is a mechanical device that increases myocardial oxygen perfusion and indirectly increases cardiac output through afterload reduction. (wikipedia.org)
  • After multiple attempts of failed weaning, intra-aortic balloon pump and high inotropes helped to wean. (perfusion.com)
  • Postoperative odds ratios (OR) of off-pump group in comparison to on-pump group were higher without reaching significance in terms of incidence of gastrointestinal complications and pneumonia (OR = 2.23 and 1.61, respectively) as well as hazard ratios (HR) on long-term follow-up for mortality and incidence of myocardial infarction (HR = 1.50 and 2.29, respectively). (uni-koeln.de)
  • The aim of off-pump is to minimize the risk of other complications like renal failure, stroke and reduce the need for blood transfusion. (apollohospitals.com)
  • Other possible complications are cerebral embolism during insertion, infection, dissection of the aorta or iliac artery, perforation of the artery and bleeding in the mediastinum. (wikipedia.org)
  • Most of the CABG's are done off pump thereby reducing post operative neurological, renal and respiratory complications for the patients. (kmchhospitals.com)
  • This analysis also revealed an OPCAB benefit concerning post-operative renal failure, blood transfusion requirement and peri-operative inotropic support. (ecrjournal.com)
  • These grafts are usually taken from the patient's own arteries and veins located in the chest (thoracic), leg (saphenous) or arm (radial). (apollohospitals.com)
  • A surgical procedure that is used to treat coronary artery disease. (ihhmalaysia-international.com)
  • With the increasing incidence of coronary heart disease, coronary heart disease has become a threat to human (especially the elderly) one of the major health diseases. (biomedres.info)
  • With the development of operation technology and the improvements of the anesthetic management level, OPCABG has become one of the effective methods which are used to cure the coronary heart disease. (biomedres.info)
  • Coexistence of coronary artery disease and cancer with both requiring surgical treatment at the same time is rare. (biomedcentral.com)
  • Pathology of chondrosarcoma, in particular, and various management strategies when coronary artery disease and cancer coexist, in general, is discussed. (biomedcentral.com)
  • The operation is performed in cases where the coronary vessels of the patient are severely affected by the disease and there is a real risk of having a heart attack, meaning also potential death. (myhealthlegacy.com)
  • When the disease of the heart is accompanied by certain other diseases such as cerebrovascular disease or renal failure, or disorders of the liver function, the risk is slightly higher - up to 2 percent. (myhealthlegacy.com)
  • What is the guarantee that the disease will not be restored again regardless of the operation and how many years can a patient with a bypass graft survive provided that his heart has been working as one of a healthy person? (myhealthlegacy.com)
  • Placing the balloon too distal from the aortic arch may induce occlusion of the renal artery and subsequent kidney failure. (wikipedia.org)
  • Each frame illustrates a single time point in the full-phase angiography sequence: baseline, arterial, microvascular, venous and residual, from a patient undergoing off-pump coronary artery bypass. (medscape.com)
  • Before initiation of CPB, the patient is given a very high dose of heparin to prevent clotting in the bypass circuit. (msdmanuals.com)
  • The patient had a stormy postoperative course, with low oxygenation, bleeding, low-cardiac-output syndrome, rhabdomyolysis of lower limb muscles, requiring multiple blood and blood product transfusion, and renal replacement therapy. (perfusion.com)
  • Once the cardiac muscle pump is operational the surgical patient starts its second life. (myhealthlegacy.com)
  • Is it possible to be made a repeated bypass of a patient who has been once operated? (myhealthlegacy.com)
  • Our study suggests that use or not use of coronary artery bypass did not influence postoperative renal function. (uni-koeln.de)
  • Intraoperative conventional angiography has proven to be overly cumbersome and associated with elevated risk of iatrogenic postoperative renal insufficiency. (medscape.com)
  • Here, we sought to determine whether pump status affects outcomes in patients with CKD. (usuhs.edu)
  • Early and long-term outcomes were analyzed with special focus on renal function. (uni-koeln.de)
  • Ten weeks after discharge, he presented with signs and symptoms of CES (e.g., livedo reticularis, acrocyanosis, acute renal failure), and a new left ventricular apical thrombus. (journalmc.org)
  • The in situ LIMA graft is shown, along with the target vessel epicardial coronary artery native circumflex marginal branches in this single frame from the 1020 frame, 34 s image data sequence captured with each indocyanin green dye fluorophobe injection. (medscape.com)
  • Serum creatinine, blood urea levels, and estimated glomerular filtration rate were determined to monitor renal function. (nih.gov)
  • An IABP was inserted by a cut down on the left femoral artery. (wikipedia.org)
  • In logistic regression models the effect of cardioplegia on 30-day mortality, IABP/ECLS (intraaortic balloon-pump/extracorporal life support) implantation, transient neurological deficit, stroke, renal failure, new-onset atrial fibrillation, and troponin T release was estimated. (minervamedica.it)
  • The pulmonic valve is located between the pulmonary arteries and the right ventricle and is responsible for allowing blood flow from the heart to the lungs. (bartleby.com)
  • Neutrophil gelatinase-associated lipocalin, α glutathione S-transferase, liver fatty acid-binding protein, and kidney injury molecule-1 were measured as urinary protein markers of renal tubular injury. (nih.gov)
  • Time courses of renal function parameters, as well as the development of acute kidney injury in 15 patients (13.5%), were irrespective of surgical technique. (nih.gov)
  • This means to circumvent the narrowed section of the coronary vessel which was struck by atherosclerotic plaque. (myhealthlegacy.com)
  • In dialysis patients with severe renal failure, the dose should not exceed 7.5 mg (half a 15 mg tablet) per day. (medicines.org.uk)
  • For patients with non-dialysed severe renal failure, see section 4.3). (medicines.org.uk)
  • Severe postoperative bleeding after PCNL is associated with renal puncture via the inferior calyx, multiple renal stones and solitary kidney stones. (archivesofmedicalscience.com)
  • Diabetes mellitus is a major cause of nephropathy and end-stage renal failure. (strath.ac.uk)
  • No dose reduction is required in patients with mild to moderate renal impairment (i.e. patients with a creatinine clearance of greater than 25 ml/min). (medicines.org.uk)
  • coronary artery bypass graft operation has been shown to be a safe and feasible procedure with the potential benefits of reduced operative bleeding and myocardial damage without prolonging intraoperative support or total operating time. (medicus.ru)
  • His renal function continued to improve and he was discharged without the need for dialysis. (journalmc.org)
  • Prospective trials comparing these procedures in patients with impaired preoperative renal function are warranted. (usuhs.edu)
  • After management by massive hydration and alkalization of urine with sodium bicarbonate, he was recovered without renal replacement therapy and discharged in good condition. (accjournal.org)
  • Contrast-induced AKI and management of renal replacement therapy will be addressed in a separate review. (nih.gov)