Although renal tumors are primarily detected on various imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), or ultrasound, they do not offer a definitive diagnosis. (e-urol-sci.com)
The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
The role of genotyping and ancillary tools, in particular immunohistochemistry, in correctly classifying these tumors is highlighted in the section on Renal Cell Carcinoma. (abdominalkey.com)
More than 80% of renal tumors of childhood are Wilms tumor (nephroblastoma) ( 1 , 2 ). (abdominalkey.com)
Postchemotherapy excision of the tumor is indicated in patients with bilateral tumors, tumors that extended beyond the midline and have shrunk, and tumors with vascular extension. (medscape.com)
Large tumors that extend beyond the midline, have vascular extension, or both are relative contraindications, since some surgeons elect to obtain tissue via surgical excision, but this may expose patients to increased surgical risks. (medscape.com)
In patients with bilateral Wilms tumors, solitary kidney, or kidney insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
Patients with tumors measuring clinically larger than 4 cm can be treated by BCT if the patient has large breasts. (basicmedicalkey.com)
Options for patients with tumors considered too large relative to the size of the breast for BCT include neoadjuvant systemic therapy to shrink the tumor or an oncoplastic procedure, involving either transfer of tissue into the breast or surgery to reduce the size of the opposite breast to obtain symmetry. (basicmedicalkey.com)
Clear cell renal2
Metastasis of clear cell renal cell carcinoma (ccRCC) to the thyroid gland is rare, and simultaneous occurrence of ccRCC and papillary thyroid carcinoma (PTC) is even rarer. (spandidos-publications.com)
Go to Renal Cell Carcinoma Treatment Protocols , Clear Cell Renal Cell Carcinoma , and Sarcomatoid and Rhabdoid Renal Cell Carcinoma for complete information on these topics. (medscape.com)
Tumor16
After the operation, the pathological examination results suggested the following: Renal clear cell carcinoma, pT1aN0M0, the tumor sized ~4.0×4×3.5 cm 3 , with no lymph node cancer metastases or distant metastasis. (spandidos-publications.com)
[6] Therefore, renal mass biopsy (RMB) is necessary to assess the histological type of the tumor, as well as to guide treatment decisions of SRMs. (e-urol-sci.com)
One patient who had 50-gene panel only also had his metastatic site (esophagus) of his tumor tested with FoundationOne. (cancerindex.org)
The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
The therapeutic approach to renal cell carcinoma (RCC) is guided by the probability of cure, which is related directly to the stage or degree of tumor dissemination. (medscape.com)
Renal cell carcinoma is an immunogenic tumor, and spontaneous regressions have been documented. (medscape.com)
Partial or radical nephrectomy may be used, depending on tumor and patient characteristics. (medscape.com)
Wilms tumor, treatment for which includes surgery (radical or partial nephrectomy), is the fifth most common pediatric malignancy and the most common type of renal tumor in children. (medscape.com)
Wilms tumor is rare in adults, accounting for only 0.5% of renal lesions. (medscape.com)
Gross nephrectomy specimen shows a Wilms tumor pushing the normal renal parenchyma to the side. (medscape.com)
Wilms tumor arises from the primitive embryonal renal tissue. (medscape.com)
Grossly, Wilms tumor is typically an intrarenal solid or cystic mass, which may displace and, in rare cases, invade the renal collecting system. (medscape.com)
The tumor extends into the renal vein in 40% of cases. (medscape.com)
Wilms tumor is bilateral in 6% of cases. (medscape.com)
According to the NWTSG protocol, the first step in the treatment of Wilms tumor is surgical staging followed by radical nephrectomy, if possible. (medscape.com)
New protocols in the management of bilateral Wilms tumor are being explored. (medscape.com)
Partial2
The patient then underwent bilateral partial renal nephrectomy and right adrenalectomy. (bvsalud.org)
These range from conventional radical approaches such as radical nephrectomy, partial nephrectomy, to more conservative approaches such as active surveillance, and some novel emerging management strategies such as various thermal ablation techniques. (e-urol-sci.com)
Resection5
In April 2018, the patient underwent radical resection of the left kidney for ccRCC at Xinqiao Hospital, Third Military Medical University (Chongqing, China). (spandidos-publications.com)
Surgical resection remains the only known effective treatment for localized renal cell carcinoma, and it also is used for palliation in metastatic disease. (medscape.com)
Surgical resection is recommended in selected patients with metastatic renal carcinoma. (medscape.com)
The study also revealed increased risk of death due to renal cell carcinoma in patients who did not undergo surgical resection of metastasis. (medscape.com)
[ 18 ] A study by Alt et al found that complete resection of multiple renal cell carcinoma metastases may be associated with long-term survival. (medscape.com)
Underwent1
METHODS: This retrospective trial consisted of 52 consecutive patients who underwent radical prostatectomy. (kocaelimj.org)
Pheochromocytoma1
Histopathologic examination reported clear renal cell carcinoma and pheochromocytoma of the right adrenal gland mass. (bvsalud.org)
Biopsy4
If imaging studies demonstrate bilateral disease, nephrectomy is not performed, but biopsy specimens are obtained. (medscape.com)
INTRODUCTION: The objective of this current study was to compare the histological findings of 12-core transrectal ultrasound (TRUS) guided prostate biopsy results with that of corresponding radical prostatectomy specimens. (kocaelimj.org)
The diagnostic ability of biopsy cores, cancer locations and the histological findings particularly Gleason grades of 12-core biopsies were compared with that of radical prostatectomy specimens. (kocaelimj.org)
Unilateral disease on biopsy was mostly associated with bilateral cancer on corresponding radical prostatectomy specimen. (kocaelimj.org)
Therapies2
Parathyroid carcinoma (PC) is a rare endocrine malignancy with no approved systemic therapies for unresectable locally invasive or distant metastatic disease. (cancerindex.org)
Dr. Spiess' research interests include novel therapies for advanced renal, bladder and penile cancer. (moffitt.org)
This review should include oncologic issues, renal functional issues, and potential complications. (medscape.com)
Unilateral1
Although end-stage kidney disease after unilateral radical nephrectomy is uncommon (0.25% in the NWTSG trial), preserving healthy kidney tissue may prevent this complication, especially in patients with an underlying intrinsic kidney disease (eg, WAGR [Wilms tumor, aniridia, genitourinary anomalies, and mental retardation] syndrome, Denys-Drash syndrome). (medscape.com)
Solitary1
About 25-30% of patients have metastatic disease at diagnosis, and fewer than 5% have a solitary metastasis. (medscape.com)
Adjuvant1
This applies as well in the adjuvant treatment of surgically resected renal cell carcinoma, for which no therapy has yet been found to offer survival benefit. (medscape.com)
The 2009 American Urological Association guideline for management of the clinical T1 renal mass recommends reviewing all available treatment options and the associated benefits and risks with the patient. (medscape.com)
The treatment of metastatic renal cell carcinoma is problematic, and, whenever possible, patients should be directed to approved and controlled clinical trials. (medscape.com)
He has dedicated his clinical practice to the surgical management of metastatic disease, particularly to the liver and peritoneum. (stanford.edu)
Tissue2
A 52 year male undergoing elective coronary artery bypass grafting was incidentally discovered to have a large soft tissue mass of variable consistency with cartilaginous elements arising from the right costal margin and adjoining ribs by a broad attachment and protruding into right pleural cavity. (biomedcentral.com)
The ureteric bud grows laterally and invades the center of the metanephric blastema, the primordial renal tissue [4]. (esur2023.com)
Genetic1
RCC comprises different subtypes with specific histopathological and genetic characteristics, of which clear cell RCC (ccRCC) is the predominant pathological type, accounting for nearly 80% of all RCC cases ( 2 ). (spandidos-publications.com)
Surgical1
Open, laparoscopic, or robotic surgical techniques may be used. (medscape.com)
Patients4
Comparative Genomic Landscape of Urothelial Carcinoma of the Bladder Among Patients of East and South Asian Genomic Ancestry. (moffitt.org)
Targeted therapy and immunomodulatory agents are considered standard of care in patients with metastatic disease. (medscape.com)
Candidates for active surveillance include selected patients older than 70 years who have asymptomatic renal masses and slow growth documented on serial imaging. (medscape.com)
Originally it was thought that local therapy had little influence on overall survival, but it is becoming clear that local therapy is responsible, at least in part, for some patients developing metastatic disease. (basicmedicalkey.com)
Urology1
In 1961, Schlegel et al first reported the usefulness of sonography in urology, for the detection of renal calculi . (medscape.com)
Masses2
Small renal masses (SRM) are defined as contrast-enhancing solid masses detected on diagnostic imaging, with a size of less than or equal to 4cm, corresponding to renal cell carcinoma stage T1a. (e-urol-sci.com)
Small renal masses (SRM) are defined as contrast-enhancing solid masses detected on abdominopelvic imaging, with a size of ≤4 cm. (e-urol-sci.com)
Disease2
Coyne T, Olson M, Bradham K, Garcon M, Gregory P, Scherch L: Dietary satisfaction correlated with adherence in the Modification of Diet in Renal Disease Study [url=https://collegegate.org/lab/purchase-cheap-caverta/] erectile dysfunction mayo clinic best purchase caverta[/url]. (ehd.org)
However about 71% of these cases was bilateral disease on radical prostatectomy specimens. (kocaelimj.org)
Endocrine1
The endocrine portion consists of cells called islets of Langerhans, which secrete varied hormone-like substances that assist the body in utilization and power elements [url=https://collegegate.org/lab/buy-eulexin-online/] man health tips in hindi buy eulexin with mastercard[/url]. (ehd.org)
Survival1
A large retrospective analysis from a single institution revealed improved cancer-specific survival advantage, even with metastasectomy of more than one lesion. (medscape.com)
Effectiveness of perioperative chemotherapy and radical cystectomy in treating bladder cancer. (moffitt.org)
Mass2
Subsequent abdominal computed tomography scan revealed heterogeneous enhancing solid mass in bilateral kidneys, avidly enhancing mass in the right adrenal gland, bilateral simple renal cortical cysts, and a pancreatic cyst. (bvsalud.org)
[1] According to the American Urological Association (AUA) guidelines, the most important indication for RMB is a mass suspicious of hematologic, metastatic, inflammatory, or infectious nature. (e-urol-sci.com)
Include1
Experimental treatment approaches include vaccines and nonmyeloablative allogeneic peripheral blood stem cell transplantation. (medscape.com)
System1
The ureteric bud divides and branches forming the collecting system (renal pelvis, infundibulae, calyces, and tubules) for urine drainage. (esur2023.com)
It was essentially a type-3 acromion, which was converted to a type 1 by aiming the burr anterior from the posterior portal excising the larger anterior spur. (mtsamples.com)
Primary1
Primary cutaneous signet-ring cell melanoma: a clinico-pathologic and immunohistochemical research of two circumstances Am J Dermatopathol. (ehd.org)