Renal cell carcinoma after nephrectomy. Medical search. Frequent questions

The study enrolled patients with metastatic clear cell renal cell carcinoma at the time of diagnosis. (ascopost.com)
Similarly, Choueiri also collaborated with William Kaelin Jr. in translational and clinical research, including recently around HIF2 inhibitors in clear-cell renal cancer, where he reported on activity and safety of MK-6482 in highly-refractory RCC patients. (wikipedia.org)
Objectives: To determine whether preoperative laboratory values are independently associated with death from clinically confined clear cell renal cell carcinoma (RCC) after radical nephrectomy. (elsevierpure.com)
Go to Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma for more complete information on these topics. (medscape.com)
Histological examination of the surgical specimen revealed clear cell renal carcinoma pT2 N0. (cdlib.org)
The purpose of this study is to assess the efficacy and safety of oral belzutifan (MK-6482) plus intravenous (IV) pembrolizumab (MK-3475) compared to placebo plus pembrolizumab, in the adjuvant treatment of Clear Cell Renal Cell Carcinoma (ccRCC) post nephrectomy. (cancersa.org.au)
The results are based on an analysis of patients with complex biopsy-proven clear cell renal cell carcinoma in the single-arm PADRES (Prior Axitinib as a Determinant of Outcome of Renal Surgery) trial . (medpagetoday.com)
Machine learning to improve prognosis prediction of metastatic clear-cell renal cell carcinoma treated with cytoreductive nephrectomy and systemic therapy. (cdc.gov)

The Kidney Cancer Risk Equation for predicting post-nephrectomy ESKD builds on the ubiquitous Kidney Failure Risk Equation and is easy to use, according to investigators. (renalandurologynews.com)
This phase 3 trial randomized patients to post-nephrectomy to 1 year of treatment with sunitinib vs placebo. (onclive.com)
Pembrolizumab as post nephrectomy adjuvant therapy for patients with renal cell carcinoma: Results from 30-month follow-up of KEYNOTE-564. (urologytimes.com)

Although the procedure is a well-established treatment modality for organ-confined clinical stage T1-2 renal tumors that are not treatable by nephron-sparing surgery, its role in the management of higher-stage tumors, although, is not yet established. (urologytimes.com)
This is known as a partial nephrectomy or kidney-sparing or nephron-sparing surgery. (mayoclinic.org)
[ 7 ] including radical or partial nephrectomy or nephron-sparing surgery. (medscape.com)
This is known as nephron-sparing surgery, or partial nephrectomy, and is commonly performed using traditional open surgery. (scienceblog.com)
Increasingly, renal cell cancers are diagnosed at an earlier stage, and nephron-sparing surgery and thermal ablation are gaining acceptance as a treatment of choice for smaller tumors. (medscape.com)

The role of cytoreductive nephrectomy (CN) in treatment of locally advanced or metastatic renal cell carcinoma (mRCC) in the era of targeted therapies (TT) is still not clearly defined. (muni.cz)
The incorporation and efficacy of targeted therapies to management has called into question the conventional standard of using cytoreductive nephrectomy prior to sunitinib. (cancertherapyadvisor.com)
CHICAGO-Sunitinib monotherapy was not inferior to cytoreductive nephrectomy (CN) followed by sunitinib among patients with intermediate- and poor-risk metastatic renal cell carcinoma (mRCC) , according to data presented during the Plenary Session at the American Society of Clinical Oncology 2018 Annual Meeting on Sunday, June 3. (cancertherapyadvisor.com)
In a study, the Selection for Cytoreductive Nephrectomy (SCREEN) score demonstrated superiority in predicting first-year mortality among patients with metastatic kidney cancer compared with an IMDC model. (renalandurologynews.com)
Cytoreductive nephrectomy for favorable risk patients with metastatic renal cell carcinoma? (bvsalud.org)
No, cytoreductive nephrectomy should no longer be routinely performed. (bvsalud.org)

Indeed, practice patterns are evolving toward a laparoscopic standard of care for many renal tumors, yet there will likely always be a role for open surgery. (urologytimes.com)
Sarcomatoid renal cell carcinoma (SRCC) is currently defined in the 2004 World Health Organization (WHO) classification of renal tumors as any histologic type of renal cell carcinoma (RCC) containing foci of high-grade malignant spindle cells. (medscape.com)
however, occasional tumors composed entirely of rhabdoid cells have been described in which no RCC component is detected despite extensive sampling. (medscape.com)
Currently, the 2004 WHO classification of renal tumors recognizes this transformation as "sarcomatoid change" or "sarcomatoid features" arising within RCC, rather than as a separate histologic entity. (medscape.com)
Radical nephrectomy is commonly preferred for treatment of tumors that extend into the inferior vena cava. (medscape.com)
Renal masses are a biologically heterogeneous group of tumors, ranging from benign masses, to indolent cancers that behave in a benign fashion, and finally, extremely aggressive and deadly cancers. (ahrq.gov)
1,2 The true incidence of renal masses (including benign lesions) is unknown, but benign lesions comprise approximately 20% of surgically resected tumors. (ahrq.gov)
No test is effective at screening for renal cell carcinoma, and most tumors are detected incidentally during an evaluation for unrelated or non-specific complaints. (ahrq.gov)
In addition to reductions in tumor size and RENAL scores, Hakimi and his colleagues reported that 34.6% of patients had a partial response to treatment, 65.4% achieved stable disease, 34.6% had tumors downstaged on imaging, and 92.3% achieved negative margins. (medpagetoday.com)
Radical nephrectomy is the standard for larger and central tumors. (medscape.com)

Studies have shown that radical nephrectomy and inferior vena cava TT removal for patients with locally advanced renal cancer can effectively improve the prognosis, and the 5-year tumor-specific survival rate is 40-65% [ 2 ]. (biomedcentral.com)

In 2017, Choueiri led a study which found that patients with metastatic papillary renal cell carcinoma benefited from savolitinib, a drug targeted to an abnormal genetic pathway causing cancerous growth. (wikipedia.org)
Rhabdoid differentiation is found in 3-7.5% of RCCs, most commonly in CCRCC, although rare cases have been reported involving papillary RCC, chromophobe RCC, and collecting duct (Bellini duct) carcinoma. (medscape.com)
4 Seventy-five percent of patients have clear cell histology (ccRCC), 10% to 15% have papillary, 5% have chromophobe histology, and the additional patients have even more rare subtypes such as translocation or renal medullary carcinoma. (onclive.com)
After excluding poor image-rendered images, 27 patients remained (benign cyst = 1, oncocytoma = 2, clear cell RCC = 15, papillary RCC = 7, and chromophobe RCC = 2). (ojp.gov)

Later that year, Choueiri presented during the plenary session of the ASCO meeting the results of KEYNOTE-564 trial that showed for the first time that immunotherapy can be efficacious in the adjuvant setting in high-risk renal cancer, culminating in the FDA approval of pembrolizumab in RCC after surgery. (wikipedia.org)
Immunotherapy with an anti-programmed cell death protein 1 (PD-1) inhibitor-pembrolizumab (Keytruda)-showed encouraging responses in patients with advanced cutaneous T-cell lymphoma (either mycosis fungoides or Sézary syndrome). (ascopost.com)
An updated analysis of the phase 3 KEYNOTE-564 trial (NCT03142334) found that adjuvant treatment with pembrolizumab (Keytruda) continued to demonstrate improved disease-free survival (DFS) vs placebo in patients with renal cell carcinoma (RCC) who are at high risk of recurrence. (urologytimes.com)

For patients with localized disease, partial or radical nephrectomy is the standard of care for most, and surveillance or ablation can be considered in a subset of patients with stage I disease. (onclive.com)

Viterbo added, "Results of the study show robot assisted partial nephrectomy to be a safe and technically feasible minimally invasive approach to kidney sparing surgery. (scienceblog.com)

If it is a high-risk Mayo grade 0 TT or even grade 1 TT, traditionally two steps were utilized including management of the inferior vena cava and removement of the TT, and then nephrectomy after changing the surgical position. (biomedcentral.com)
The aim of the study was to explore the feasibility of single position transperitoneal laparoscopic radical nephrectomy (LRN) and high-risk Mayo 0 and 1 tumor thrombectomy and the surgical techniques were described in detail. (biomedcentral.com)
Our outcomes compare favorably to published data on open surgical radical nephrectomy in this setting, and HALN should be considered in centers with experience with this technique. (nih.gov)
REINFORCE (evaluation of robot-assisted surgical services in NHS) and PARTIAL (a randomised trial of partial vs radical nephrectomy for renal cell carcinoma). (abdn.ac.uk)
Experienced laparoscopic surgeons at high volume centers, such as Fox Chase, are now using the da Vinci(R) robot assisted surgical system for patients with kidney cancer, or renal cell carcinoma. (scienceblog.com)
The advanced technology has enabled faster and greater technical proficiency allowing for completion of complex surgical procedures, facilitating a minimally invasive approach for partial nephrectomy. (scienceblog.com)
Renal mass sampling can be done by fine needle aspiration with a reading of the sample by a cytopathologist, or by core biopsy with a reading of the sample by a surgical pathologist. (ahrq.gov)
The most common treatment for kidney cancer is a surgical procedure called a nephrectomy. (massgeneral.org)
Secondary outcomes included change in tumor diameter, RENAL nephrometry score, renal function based on eGFR, tumor response, and surgical complications. (medpagetoday.com)
Six of the 26 patients had Clavien grade III-IV surgical complications after partial nephrectomy, including urine leaks in four patients. (medpagetoday.com)
Introduction: For a range of kidney abnormalities, including both neoplastic and nonneoplastic disorders, nephrectomy is a popular surgical treatment. (who.int)
Surgical resection remains the only known effective treatment for localized renal cell carcinoma, and it is also used for palliation in metastatic disease. (medscape.com)

In a study, diabetes increased the odds of pathologic upgrading of renal cell carcinoma by 65% and 32%, among patients undergoing partial and radical nephrectomy, respectively. (renalandurologynews.com)
22 (12%) and 158 (88%) patients underwent partial and radical nephrectomy, respectively, and 47 (26.1%) of whom were treated with a laparoscopic approach.Mean patient age was 82.3 years. (elsevierpure.com)

The risk of the emergence of pulmonary metastasis of renal carcinoma after surgery has been estimated between 30 and 40 percent, with average delay of 15 months [ 1 ]. (cdlib.org)
The occurrence of metastasis of renal cell carcinomas in the head and neck region is extremely rare. (thieme-connect.com)

Right nephrectomy for high grade sarcomatoid T4 renal cell carcinoma. (cancer.org)
Focal spindling due to noncohesion of tumor cells is not considered to represent sarcomatoid differentiation. (medscape.com)
Sarcomatoid differentiation also occurs in around 29% of carcinomas of the collecting duct of Bellini. (medscape.com)
13 Inclusion criteria comprised patients with a clear-cell component and met criteria for a high risk of recurrence (pT2 with nuclear grade 4 or sarcomatoid differentiation, pT3+, pTanyN+, or M1 NED post completely resected metastatic disease within 1 year of nephrectomy). (onclive.com)

Comparative Genomic Landscape of Urothelial Carcinoma of the Bladder Among Patients of East and South Asian Genomic Ancestry. (moffitt.org)

The data show that laparoscopy is as effective as open surgery for the management of locally advanced renal cancers,' said Dr. Aron, who worked on the study with Inderbir S. Gill, MD, MCh. (urologytimes.com)
Kidney and renal pelvis cancers are one of the 10 most common new malignant diagnoses in both men and women in the United States, with an estimated 52,360 new cases in men and 29,440 new cases in women per year. (onclive.com)
4 While renal cell carcinoma only represents 2% of adult cancers, it is among the most lethal, with approximately 35% of patients dying within 5 years of diagnosis. (ahrq.gov)
About 9 out of 10 kidney cancers are renal cell carcinomas. (massgeneral.org)

Nephrectomy has been the standard of care for metastatic renal cell carcinoma for 20 years, but now that targeted therapies have improved outcomes substantially, the question is whether all patients should have nephrectomy as well as targeted therapy. (ascopost.com)
Liver metastasis, high-grade tumor, absence of CN, non-clear cell histology, and MSKCC (Memorial Sloan-Kettering Cancer Center) poor prognosis status were associated with adverse treatment outcomes. (muni.cz)
A retrospective study revealed no significant difference in 36-month progression-free survival and renal function outcomes in patients with small renal masses. (renalandurologynews.com)
To assess outcomes after hand-assisted laparoscopic nephrectomy (HALN) for renal cell cancer tumor thrombus confined to the renal vein and to compare outcomes with published series in this setting. (nih.gov)
Looking at renal functional outcomes at the 1-month mark, renal function outcomes were preserved pretty well," Hakimi said. (medpagetoday.com)

Intermediate-term oncologic results after laparoscopic radical nephrectomy for locally advanced renal cell carcinoma are similar to those of open nephrectomy. (urologytimes.com)
Dr. Mohamed Abdelsalam and his co-authors sought out to examine image-guided thermal ablation of recurrent renal cell carcinoma (RCC) post-ipsilateral partial nephrectomy, and its oncologic benefits. (urotoday.com)

We evaluated the morbidity of nephrectomy in patients older than 80 years of age.Between June 2002 and March 2011, 2,530 patients underwent surgery for renal tumor at 5 French academic centers. (elsevierpure.com)
Thirteen patients underwent HALN for radiologic T3b disease (tumor thrombus confined to the renal vein on preoperative computed tomography) under the care of three surgeons at two centers between 1997 and 2006. (nih.gov)
A total of 1674 patients underwent nephrectomy during the study period. (ima.org.il)
Fourteen patients underwent nephrectomy for neoplastic conditions such as Wilm'stumor and renal cell carcinoma (RCC). (who.int)

Other types of kidney cancer include transitional cell carcinoma of the renal pelvis and Wilms tumor. (massgeneral.org)

1 The median overall survival was 18.4 months for patients treated with targeted therapy using sunitinib vs 13.9 months for those treated with nephrectomy followed by sunitinib-the current standard of care. (ascopost.com)
Sunitinib alone is noninferior to nephrectomy followed by sunitinib in some intermediate- and poor-risk patients with metastatic renal cell carcinoma. (ascopost.com)
Patients were randomized 1:1 to receive nephrectomy followed by sunitinib or sunitinib alone. (ascopost.com)

Nearly 30 percent of all patients with renal cell carcinoma will eventually present with metastatic disease after radical nephrectomy. (cdlib.org)

To explore the feasibility of single-position laparoscopic radical nephrectomy (LRN) and tumor thrombectomy for left renal cell carcinoma with high-risk Mayo 0 and 1 tumor thrombus (TT). (biomedcentral.com)

The retrospective study, presented by Monish Aron, MD, a clinical fellow in advanced laparoscopic urology at the Cleveland Clinic, represents one of the largest series to date specifically evaluating laparoscopic nephrectomy for higher-stage renal masses. (urologytimes.com)
See Renal Cell Carcinoma: Recognition and Follow-up , a Critical Images slideshow, to help evaluate renal masses and determine when and what type of follow-up is necessary. (medscape.com)
This article details research associated with the development of software to assess the potential aggressiveness of incidentally detected renal masses. (ojp.gov)
Renal masses were correlated with tumor roughness. (ojp.gov)
Conclusion of the research found that using basic CT imaging software, tumor topography ("roughness") can be quantified and correlated with histologies such as RCC subtype and could lead to determining aggressiveness of small renal masses. (ojp.gov)
All solid renal masses and cystic lesions with solid components are suspicious for renal cell carcinoma. (ahrq.gov)
1, 19-21 In addition, all current standard imaging modalities (CT, magnetic resonance imaging (MRI) and ultrasound) are able to provide insight into whether renal masses are localized or locally advanced, thus suggesting pathologic aggressiveness. (ahrq.gov)
SAN DIEGO -- Use of neoadjuvant axitinib (Inlyta) resulted in significant reductions in tumor size and complexity, enabling partial nephrectomy in a cohort of patients with highly complex renal masses in whom the procedure would ordinarily not be feasible, according to an interim analysis from a small phase II trial. (medpagetoday.com)
For patients that have large masses that have imperative indications for partial nephrectomy -- such as a decreased eGFR [estimated glomerular filtration rate] or some other indication that would make them dialysis dependent if they underwent a radical nephrectomy -- using a neoadjuvant approach can make them amenable to a partial nephrectomy and allow them to conserve more renal function and avoid dialysis dependence or some other complication from chronic kidney disease. (medpagetoday.com)
So we showed that in this complex cohort of patients, axitinib can be used to cytoreduce masses and enable partial nephrectomy in a highly specific cohort of patients with imperative indications for the procedure," Hakimi concluded, adding that accrual for the trial is ongoing, with a targeted enrollment of 5o patients. (medpagetoday.com)

Enrolled participants had clear cell histology, no evidence of brain metastases, acceptable organ function, and were eligible for sunitinib therapy. (cancertherapyadvisor.com)
The imaging examination of case 3 showed left kidney tumor with retroperitoneal lymphadenopathy, left renal vein TT (Mayo grade 0) and multiple lung metastases. (biomedcentral.com)
The pancreas is an uncommon but recognizable site for metastases from renal cell carcinoma (RCC). (scirp.org)
Isolated pancreatic RCC metastases are still rarer and often present years after initial nephrectomy. (scirp.org)
The median interval between initial curative nephrectomy and re-presentation with pancreatic metastases w as 12.5 years. (scirp.org)
K. Chiu, A. Razack and A. Maraveyas, "Targeted Therapy in the Management of Elderly Patients with Pancreatic Metastases from Renal Cell Carcinoma," Journal of Cancer Therapy , Vol. 4 No. 9B, 2013, pp. 15-21. (scirp.org)

Neoadjuvant immunotherapy with the programmed cell death protein 1 (PD-1) inhibitor nivolumab (Opdivo) is safe and feasible in early-stage non-small cell lung cancer (NSCLC). (ascopost.com)
Moffitt Cancer Center continues to distinguish itself as a world leader in the development of novel immunotherapy treatments, capitalizing on the natural power of the body's immune system to defend itself against the growth and spread of cancerous cells. (moffitt.org)
It is a phase 2b randomized trial of autologous dendritic cell immunotherapy (CMN-001) plus standard treatment for advanced renal cell carcinoma after a nephrectomy ( MCC 21083 ). (moffitt.org)
This CMN-001 is an autologous, tumor antigen-loaded dendritic cell immunotherapy. (moffitt.org)

We successfully treated the patient with locally advanced HLRCC-associated kidney cancer, who has received active surveillance because of at-risk individual, by radical nephrectomy and extended retroperitoneal lymph node dissection, and examined surgically resected samples from a molecular point of view. (biomedcentral.com)
We recommended that 13 at-risk individuals from a family with HLRCC should receive active surveillance for early detection of renal cancer. (biomedcentral.com)
Resected samples showed two thirds tumor tissue necrosis as well as high expression of serine/threonine kinase Akt and low expression of nuclear factor E2-related factor 2 (Nrf2) which activates anti-oxidant response and protects against oxidative stress in viable cancer cells. (biomedcentral.com)
Conclusions: Abnormal preoperative laboratory values including hypercalcemia, anemia, and elevated ESR are independently associated with increased risk of cancer-specific death from clinically confined clear cell RCC. (elsevierpure.com)
These data demonstrate that HALN for renal cell cancer with tumor thrombus limited to the renal vein is feasible. (nih.gov)
For patients with advanced non-small cell lung cancer (NSCLC) harboring the ALK gene rearrangement, ceritinib (Zykadia) provided longer progression-free survival than chemotherapy in patients previously treated with chemotherapy and crizotinib (Xalkori), but gastrointestinal toxicity was. (ascopost.com)
We wanted to focus specifically on patients with clear cell kidney cancer , and that's why we mandated the biopsy ahead of time. (medscape.com)
We ultimately ended up enrolling 24 patients with clear cell kidney cancer, all biopsy proven, all locally advanced disease, and gave them axitinib for a total of 12 weeks. (medscape.com)
The most common type of kidney cancer is renal cell carcinoma. (mayoclinic.org)
Depending upon the stage and severity of cancer, surgeons may remove the affected kidney altogether - a procedure known as a nephrectomy or radical nephrectomy. (mayoclinic.org)
Prospective Randomized Trial of Interferon Alfa-2a Plus Vinblastine versus Vinblastine Alone in Patients with Advanced Renal Cell Cancer," Journal of Clinical Oncology, Vol. 17, No. 9, 1999, pp. 2859-2867. (scirp.org)
R. I. Fisher, S. A. Rosenberg and G. Fyfe, "Long-Term Survival Update for High-Dose Recombinant Interleukin-2 in Patients with Renal Cell Carcinoma," The Cancer Journal From Scientific American, Vol. 6, Suppl. (scirp.org)
Dr. Spiess' research interests include novel therapies for advanced renal, bladder and penile cancer. (moffitt.org)
1 Renal cell carcinoma (RCC) is the most common malignancy of the kidney and globally accounts for approximately 2% of cancer diagnoses and deaths. (onclive.com)
We describe a patient with renal cell cancer of the pelvic kidney who underwent radical nephrectomy at our institute. (karger.com)
Histological examination revealed a pT2N0GIV renal cell cancer. (karger.com)
The histopathology report indicates the grade and the stage of the carcinoma or cancer in the right kidney tissue. (ndtv.com)
Renal cell carcinoma (RCC) and urothelial cell carcinoma (UCC) are the two most common types of kidney cancer. (ahrq.gov)
Median survival for patients with pT3a disease and perinephric or renal sinus fat involvement was 36 months with a 36% 5-year cancer specific survival rate. (nih.gov)
Cancer is caused by malignant (cancerous) cells that grow and multiply without control. (massgeneral.org)
When cancer begins in the tissues of a kidney, it is called kidney cancer (or renal cancer). (massgeneral.org)
According to the ACS , renal cell carcinoma (also known as renal cell cancer) is "by far the most common type of kidney cancer. (massgeneral.org)
Immunotherapies include checkpoint inhibitory antibodies, chimeric antigen receptor (CAR) T-cells, cancer vaccines, and oncolytic viruses. (moffitt.org)
Now researchers at Moffitt are working to develop a dendritic cell vaccine targeting HER3, a protein involved in the growth and spread of many different cancer types. (moffitt.org)
Dendritic cell vaccines can potentially be used to treat different cancer types. (moffitt.org)
Dr. Jad Chahoud , a medical oncologist in the Department of Genitourinary Oncology at Moffitt Cancer Center, is conducting a study on dendritic cells for kidney cancer. (moffitt.org)
Renal cell carcinoma (see the image below) is the most common type of kidney cancer in adults. (medscape.com)
Renal cancer occurs in a sporadic (nonhereditary) and a hereditary form, and both forms are associated with structural alterations of the short arm of chromosome 3 (3p). (medscape.com)
Genetic studies of the families at high risk for developing renal cancer led to the cloning of genes whose alteration results in tumor formation. (medscape.com)

Nephrectomy may be more appropriate for low-volume disease, and initiating therapy with sunitinib alone may be more appropriate for high-volume disease as initial therapy. (ascopost.com)
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant tumor susceptibility syndrome, and the disease-related gene has been identified as fumarate hydratase (fumarase, FH ). (biomedcentral.com)
Disease free survival of 124 patients undergoing robotic partial nephrectomy. (biomedcentral.com)
Acquired cysts can be simple or part of acquired cystic kidney disease (ACKD), also called acquired renal cystic disease (ARCD). (medscape.com)
Patients with more advanced disease may present with signs and symptoms due to cyst hemorrhage or infection, or distant metastasis from a malignant renal neoplasm. (medscape.com)
Dialysis prolongs the patient's survival to allow more time for acquired renal cystic disease to occur. (medscape.com)
Compensatory growth: The profound loss of renal tissue in end-stage kidney disease promotes tubular cell hypertrophy and hyperplasia. (medscape.com)
Treatment protocols for renal cell carcinoma are provided below, including treatment of localized and advanced disease and recommendations for patients with predominantly clear cell carcinoma and those with predominantly non-clear cell carcinoma. (medscape.com)
Chronic Kidney Disease Chronic kidney disease (CKD) is long-standing, progressive deterioration of renal function. (msdmanuals.com)

It is feasible to control left renal vein and partial inferior vena cava through descending colon mesentery in a single position during LRN and tumor thrombectomy for the treatment of high-risk Mayo grade 0 and 1 TT. (biomedcentral.com)

In the surgery arm, sunitinib was initiated 3 to 6 weeks after nephrectomy. (ascopost.com)
Chicago, IL (UroToday.com) Renal cell carcinoma is often treated with surgery. (urotoday.com)
Left renal vein TT is more complicated than right renal vein TT and the length of Mayo grade 0 TT determines the complexity of the surgery. (biomedcentral.com)

Allogeneic hematopoietic stem cell transplantation is the only potentially curative treatment for myelofibrosis. (ascopost.com)
PURPOSE: Up to 10% of recurrences develop beyond 5 years after curative treatment of localized renal cell carcinoma (RCC). (koreamed.org)
The incidence of metastasis in renal cell carcinomas can be observed even many years following initial curative treatment of the primary tumor. (thieme-connect.com)

A 48-year-old woman with a left renal tumor and involvement of multiple regional lymph nodes with high accumulation of fluorine-18-deoxyglucose on positron emission tomography was treated with axitinib as a neoadjuvant therapy. (biomedcentral.com)
All patients with left renal cell carcinoma and venous TT (high-risk Mayo grade 0 and 1) who were performed single-position LRN and tumor thrombectomy were involved. (biomedcentral.com)
After the renal artery was controlled by Hem-o-lok, the left renal vein was dissected through descending colon mesentery. (biomedcentral.com)
The left renal vein was divided by EndoGIA for high-risk Mayo grade 0 TT. (biomedcentral.com)
For Mayo grade 1 TT, part of the inferior vena cava was blocked by a bulldog clamp after milking the TT into the left renal vein and the inferior vena cava was sutured after complete excision of the TT. (biomedcentral.com)
If it is a low-risk Mayo grade 0 TT, the end of the TT is on the left side of the mesenteric artery, the left renal vein can be fully controlled by traditional approach. (biomedcentral.com)
In order to simplify the procedure, we explored the trans-mesocolon approach to fully dissect the left renal vein to the inferior vena cava in single position to treat high-risk Mayo 0-grade and grade 1 TT. (biomedcentral.com)

The primary indication for kidney transplantation is End-stage renal failure. (msdmanuals.com)

Reflux of infected urine into the renal pelvis is the usual mechanism. (msdmanuals.com)

Research into the cystic fluid and epithelium suggests that the cysts arise from proliferation of renal tubules. (medscape.com)
William Krassan came to Fox Chase after learning he had renal cell carcinoma in the right kidney and cystic renal cell carcinoma in the left. (scienceblog.com)

Thus to confirm the renal neoplasia origin of a pulmonary mass, percutaneous fine-needle aspiration biopsy (FNAB) is often used. (cdlib.org)
Percutaneous fine needle aspiration biopsy of the lung via the right anterior chest wall, using a 20 gauge fine needle, showed metastasis from renal cell carcinoma. (cdlib.org)

Pseudoaneurysms following partial nephrectomies for Wilms' Tumor and renal cell carcinoma. (llu.edu)

In the modern era of targeted therapy, some patients with metastatic renal cell carcinoma may be able to forgo nephrectomy and be treated with sunitinib (Sutent) alone, according to results of the phase III CARMENA trial reported during the Plenary Session at the 2018 ASCO Annual Meeting. (ascopost.com)
What's New in the Field of Neoadjuvant Therapy and Renal Cell Carcinoma? (medscape.com)
The latest addition to oncotherapy is the use of dendritic cell (DC) vaccine therapy. (moffitt.org)
A dendritic cell vaccine is a cross between a vaccine and a cell therapy. (moffitt.org)
CMN-001 is indicated for the treatment of intermediate/poor-risk patients with advanced renal cell carcinoma (RCC) in combination with nivolumab plus ipilimumab as first-line therapy and in combination with lenvatinib plus everolimus as 2nd line therapy post-first-line failure. (moffitt.org)

Results of the research investigated 30 subjects that underwent partial or radical nephrectomy. (ojp.gov)

Simple Enucleation Is Equivalent to Traditional Partial Nephrectomy for Renal Cell Carcinoma : Results of a Non-randomized, Retrospective, Comparative Study. (unifi.it)
A retrospective analysis was conducted of all patients who underwent nephrectomy over a period of 30 years (1987-2016) in a large tertiary medical center. (ima.org.il)

Anatomy17

Organisms2

Diseases88

Chemicals and Drugs44

Analytical, Diagnostic and Therapeutic Techniques and Equipment55

Phenomena and Processes23

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science6

Named Groups1

Health Care19

Clear cell renal8

Post-nephrectomy3

Nephron-sparing5

Cytoreductive6

Tumors10

Advanced renal cancer1

Papillary4

Pembrolizumab3

Radical nephrectomy is the standard1

Robot-assisted partial nephrectomy1

Surgical12

Partial and radical nephrectomy2

Metastasis of renal2

Sarcomatoid4

Urothelial Carcinoma1

Cancers4

Outcomes5

Oncologic2

Patients underwent4

Transitional Cell Carc1

Followed by sunitinib3

Metastatic disease1

Laparoscopic radical1

Masses10

Metastases6

Immunotherapy4

Cancer29

Disease9

Feasible1

Surgery3

Curative3

Left renal7

Stage renal1

Pelvis1

Cystic2

Fine-needle asp2

Wilms1

Therapy5

Underwent partial1

Retrospective2