• 1999. Exposure rates associated with high level fluoroscopic equipment and data recording modes. (cdc.gov)
  • Introduction 1 Situations such as prolonged exposure to naturally occurring radionuclides (e.g., radon), improper operation of radioactive sources, and leakage of nuclear materials may considerably increase the risk of radioactive substances entering the body through inhalation, ingestion, and absorption, thereby resulting in internal radiation exposure. (sinap.ac.cn)
  • When these image detectors are stimulated by light following radiation exposure, they release the energy, and this light is then converted to rows and columns of pixels that represent the various x-ray intensities. (medscape.com)
  • In order to obtain information on human exposure, we conducted a monitoring study on human milk with three series of mother-child pairs (2004, 2005, 2006), with focus on cosmetic UV filters in relation to other endocrine disrupters. (researchgate.net)
  • Testing radioanalytical laboratory capabilities during a nuclear/radiological incident was an exercise objective, and developing clear messaging on low-dose exposure and long-term health concerns was a primary output of the exercise. (cdc.gov)
  • The more important radionuclides contributing to dose with exposure starting at day D + 1 were 239Np and 133I. (cdc.gov)
  • Administer the first dose as soon as possible after suspected or confirmed exposure to myelosuppressive doses of radiation, and a second dose one week after. (drugs.com)
  • Exposure to a variety of TCE-related compounds, which include metabolites of TCE and other parent compounds that produce similar metabolites, can alter or enhance TCE metabolism and toxicity by generating higher internal metabolite concentrations than would result from TCE exposure by itself. (who.int)
  • Numerous studies are under way to identify specific imaging markers for different types of dementia, including cerebral volumetric measurements, diffusion imaging, spectroscopy, very-high-field MRI scans of senile plaques, and PET scan markers of senile plaques. (medscape.com)
  • The HEXITEC$_{MHz}$ system aims to deliver the same high resolution spectroscopy but at a continuous frame rate of 1 MHz. (cern.ch)
  • In this study, we use diffuse reflectance spectroscopy, a non-invasive optical fiber-based technique, to determine the effects of different doses of radiation on the tumor microenvironment, as well as to determine the sensitivity of diffuse reflectance spectroscopy to low doses of radiation that are used in the treatment of certain cancers. (bioone.org)
  • Our findings show that diffuse reflectance spectroscopy is sensitive to microenvironmental changes in tumors treated with doses of radiation as low as 1 Gy/fraction. (bioone.org)
  • When the tumors grew to 200 mm 3 , we distributed the mice into a control group or one of three radiation groups: 1, 2, or 4 Gy/fraction, and they underwent treatment for five consecutive days. (bioone.org)
  • DESIGN, SETTING, AND PARTICIPANTS: The results of a systematic literature search informed a two-round Delphi process with a panel of 28 PCa experts in medical or radiation oncology, urology, radiology, medical physics, and nuclear medicine. (bvsalud.org)
  • The ability of circulating tumor DNA liquid biopsy assays to monitor cancer in situ also allows for the ability to monitor response to therapy, to detect minimal residual disease and as an early biomarker for cancer recurrence. (frontiersin.org)
  • The main goal of RT consists in delivering a precise dose of radiation in a target volume, such as tumor, promoting the tumor cells eradication with as minimal damage as possible in surrounding normal tissues ( 13 ). (frontiersin.org)
  • Real-time monitoring of the effects of radiation on the tumor microenvironment can contribute to the development of better treatment plans. (bioone.org)
  • There was a significant increase in tumor vascular oxygenation, which was primarily due to an increase in oxygenated hemoglobin, in response to a 1 Gy/fraction of radiation, while there was a decrease in tissue scattering in response to all doses of radiation. (bioone.org)
  • Immunohistochemical analysis revealed that tumor cell proliferation and apoptosis were higher in irradiated groups compared to the control group. (bioone.org)
  • High Precision X-ray Measurements 2021 conference is the second edition of the HPXM2018 workshop, held at the INFN Laboratories of Frascati in 2018. (infn.it)
  • Expression and estrogen sensitivity of target genes and nuclear receptor coregulators were altered at mRNA and protein levels in adult uterus, prostate and brain. (researchgate.net)
  • In this study, spatially and temporally dependent isotopic compositions from a simulated nuclear detonation and Monte Carlo methods were used to relate contamination activity levels to the measurable radiation levels at select distances away from an individual with whole-body contamination. (cdc.gov)
  • Calculations are presented for radionuclide concentrations in air, dose to staff from inhalation, and how exposures and the resulting doses can be altered by air-turnover rates and the use of filters with varying efficiency. (cdc.gov)
  • The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and of exposures to other agents, such as radiation and viruses. (who.int)
  • The Monographs represent the first step in carcinogenic risk assessment, which involves examination of all relevant information in order to assess the strength of the available evidence that certain exposures could alter the incidence of cancer in humans. (who.int)
  • High exposures have occurred to various occupational groups. (who.int)
  • To quantitatively evaluate the radiation dosages for individual organs and tissues under such circumstances, it is critical to accurately determine the distribution of radionuclides in the body and the corresponding radioactivity. (sinap.ac.cn)
  • The ability to fully evaluate the correlation and sensitivity of CLI to PET is critical to progress this technique further for use in high-throughput screening of pharmaceutical compounds. (snmjournals.org)
  • Glomerulonephritis: Evaluate and consider dose-reduction or interruption of UDENYCA if causality is likely. (drugs.com)
  • The goal of the FORESEE Study is to evaluate the performance of CNSide in monitoring the LM's response to treatment and to assess the impact of CNSide on treatment decisions made by Physicians. (stanford.edu)
  • The PET and CLI data presented confirm the correlation and dynamic sensitivity of this new imaging modality. (snmjournals.org)
  • One of the treatments applied in cancer is radiotherapy (RT), a therapeutic modality that uses ionizing radiation to induce damage in unwanted cells. (frontiersin.org)
  • Throughout the measurements, the radiation background is the key factor that determines the sensitivity of the counter. (sinap.ac.cn)
  • CLI measurements were radiance, radiance per injected dose (radiance/ID), and total radiant volume. (snmjournals.org)
  • The U.S. National Council on Radiation Protection and Measurements (NCRP) conducted a retrospective assessment of the U.S. data, and the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) performed a similar worldwide assessment for 2009-2018 (with most data from 2014 to 2017). (cdc.gov)
  • CLI uses radionuclides commonly used in PET and SPECT, thereby allowing researchers the ability to monitor a wide range of energy-qualified radionuclides for distribution and uptake. (snmjournals.org)
  • Characterizing, modeling, monitoring and remediating radionuclides in the subsurface: What is needed? (tib.eu)
  • There is a critical need to identify readily translatable adjuncts to potentiate the dismal median survivals of only 15-20 months in glioblastoma (GBM) patients after standard of care, i.e., concurrent Temozolomide (TMZ) and radiation (XRT) therapy. (mdpi.com)
  • To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. (stanford.edu)
  • It has been found promising in the diagnosis of primary lung cancer and its remote metastases, although it is less sensitive than positron emission tomography in detection of metastatic lung cancer in hilar and mediastinal lymph nodes. (medscape.com)
  • Sustained lymphatic delivery enables lower dosing and fewer administrations to potentially improve therapeutic response while reducing adverse effects and costs. (gatech.edu)
  • PET data analysis was performed using percentage injected dose per cubic centimeter of tissue (%ID/cm 3 ), average standardized uptake values, and total glycolytic volume. (snmjournals.org)
  • P = 0.053), but some of the nonmalignant lesions showed high uptake. (snmjournals.org)
  • Although the sensitivity of octreotide scanning is low for adrenal pheochromocytomas and juxtarenal paragangliomas (25%) owing to high renal uptake and excretion of 111In octreotide, its sensitivity is high for metastatic pheochromocytoma (87%) and paragangliomas of the head and neck (chemodectomas). (medscape.com)
  • Imaging, understanding, and managing radiotherapy inflammation and radiation necrosis. (usherbrooke.ca)
  • 1 Early clinical studies of the EGFR monoclonal antibody in combination with radiotherapy primarily included head and neck squamous cell carcinoma, and the study of its combination with radiation therapy for NSCLC was performed relatively late. (dovepress.com)
  • Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML): Monitor patients with breast and lung cancer using UDENYCA in conjunction with chemotherapy and/or radiotherapy for signs and symptoms of MDS/AML. (drugs.com)
  • This paper provides a methodology for calculating inhalation doses to public health and other response personnel at such facilities who would be receiving and assisting potentially contaminated persons from whom particles can be resuspended. (cdc.gov)
  • The highest calculated dose via inhalation with no respiratory protection was 0.23 mSv for the Base Case. (cdc.gov)
  • CRC screening efforts are directed toward removal of adenomas and sessile serrated lesions and detection of early-stage CRC. (lww.com)
  • In previously published work, we demonstrated the first in vivo use of Cerenkov luminescence imaging (CLI) with a highly sensitive and ultracooled charged-coupled device camera, allowing detection of this optical emission ( 15 ). (snmjournals.org)
  • Cerenkov radiation is produced when a high-energy, charged particle travels with a velocity that exceeds the speed of light through a medium ( 16 - 19 ). (snmjournals.org)
  • Sunlight is a portion of the electromagnetic radiation given off by the Sun, in particular infrared, visible, and ultraviolet light. (wikipedia.org)
  • The ultraviolet radiation in sunlight has both positive and negative health effects, as it is both a requisite for vitamin D3 synthesis and a mutagen. (wikipedia.org)
  • Phototherapy lights emit minimal ultraviolet (UV) radiation that does not cause erythema and is completely absorbed by the acrylic Plexiglas covering of the tubes. (medscape.com)
  • In this study, we conducted a systematic experimental investigation on the radiation background outside and inside four representative body counters with assorted designs using a variety of radiation detectors, including high-purity germanium detectors, CdZnTe detector, radon emanometer, and gamma-ray dosimeter. (sinap.ac.cn)
  • In overnight trials, the device detected sleep apnea and hypopnea with 95% precision and 100% sensitivity compared to data professionally scored by licensed clinicians. (gatech.edu)
  • I n the wake of the success of the 2018 edition, HPXM2021 is planned with the twofold aim to consolidate the existing interconnections between the research teams and foster creating new ones, offering the opportunity for all the participants to discuss and share the results of their activities focusing on a common protagonist: X-ray precision detection. (infn.it)
  • Preclinical studies suggested that the epidermal growth factor receptor (EGFR) monoclonal antibody was a radiation-sensitizing agent because it increased the rate of apoptosis, regulated the cell cycle, reduced radiation resistance, and increased radiation injuries. (dovepress.com)
  • The International Workshops on Radiation Imaging Detectors are held yearly and provide an international forum for discussing current research and developments in the area of position sensitive detectors for radiation imaging, including semiconductor, gas and scintillator-based detectors. (cern.ch)
  • This can be accomplished by achieving high rates of adherence, quality monitoring and improvement, following evidence-based guidelines, and removing barriers through the spectrum of care from noninvasive screening tests to screening and diagnostic colonoscopy. (lww.com)
  • 4 Primary care practitioners are uniquely positioned to influence adherence to screening procedures, recognize those at highest risk of disease, and address modifiable risk factors in their patients. (naturalmedicinejournal.com)
  • It is, however, the level of documentation and proof of accuracy required by the relevant legislation, rather than its analytical capability, that generally determines whether a particular instrument can be used evidentially. (druglibrary.net)
  • 1993. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. (cdc.gov)
  • Body counter Radiation background Shielding room In vivo measurement. (sinap.ac.cn)
  • Identifying the viral components themselves-rather than the body's reaction to the viral presence (i.e., antibodies)-potentially improves early detection in asymptomatic subjects. (gatech.edu)
  • 9 Identifying the risk factors relevant for individual patients provides an opportunity for clinicians to educate patients on how to modify their risk. (naturalmedicinejournal.com)
  • Rather, its genotoxic effects are limited to indirect clastogenicity occurring in select cell types, and only when high dose and time thresholds are exceeded. (cdc.gov)
  • For the bottom up part, we have performed extensive testing with very high sampling scheme so as to quantify the main effects. (spie.org)
  • This includes studies on the effects of low doses, group related radiation sensitivity, and epidemiological studies where sampling and handling of biological samples is included. (europa.eu)
  • Screening and early diagnosis have profound effects on the prognosis of individuals with colorectal cancer, and recognizing those at high risk may save lives through early detection. (naturalmedicinejournal.com)
  • Indeed, it has been shown that miRNAs play an important role in gene expression, mainly when associated with the monitoring of several cell and metabolic pathways, being also an essential component of the gene silencing machinery in most eukaryotic organisms ( 4 , 8 ). (frontiersin.org)
  • however, the sensitivity of modern imaging systems makes it possible to detect and quantify the light. (snmjournals.org)
  • Idea: Create a Real-time Aspiration Alarm Device on Tracheal Stent (RAAD-on-TS) to both detect and intervene during aspiration in real-time for chronic aspiration patients and high-risk aspiration population. (clevelandclinic.org)
  • Today, it can already detect deviations in process monitoring data and implement quality control in real time. (compamed-tradefair.com)
  • Healthcare represents one of the biggest sectors in advanced industrialised countries (the OECD average in 2017 was 8.8 percent of GDP), yet as a market it may be one of the most complicated to access: fragmentation, the strong role of the public sector, the high level of regulation, the often competing interests of powerful stakeholders, and other factors make life difficult for industry. (semieuconf.org)
  • Optimiser les soins des patients atteints du cancer de la prostate résistant à la castration en utilisant une stratégie de triple traceur en imagerie moléculaire et en radiothérapie ciblée. (usherbrooke.ca)
  • The expert panel recommends PSMA PET to be used for staging the majority of patients with unfavourable intermediate and high risk, and for restaging of suspected recurrent PCa. (bvsalud.org)
  • Over half of cancer patients undergo radiation therapy (RT). (nature.com)
  • Increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Subsyndrome of Acute Radiation Syndrome). (drugs.com)
  • Chest imaging in patients with acute respiratory failure plays an important role in diagnosing, monitoring and assessing the underlying disease. (ersjournals.com)
  • Radiation therapy plays an important role in cancer treatment, as it is an established method used as part of the treatment plan for the majority of cancer patients. (bioone.org)
  • Systems are now entering clinical practice that can analyse CT scans of a patient with cancer and by combining this data with learning from previous patients, provide a radiation treatment recommendation, tailored to that patient which aims to minimise damage to nearby organs. (bmj.com)
  • Due to the severity of underlying disease and frequent need of placement of monitoring devices, ICU patients are very likely to develop complications related to underlying disease process and interventions. (bvsalud.org)
  • Conclusions Based on a multidisciplinary approach, items relevant for fistula management were identified and algorithms on diagnosis and treatment of pCD were developed. (bmj.com)
  • Anomaly detection algorithms generate anomaly scores based on properties of the neural network, providing a measure of severity by assessing how anomalous an instance appears compared to the healthy distribution. (gatech.edu)
  • Non-pharmacological interventions included supportive care, 3 nutritional correction, and symptom monitoring and evaluation frequency. (ehd.org)
  • Standard of Care methods to diagnose, or assess the treatment response of LM (Clinical Evaluation, MRI and Cytology) have limited sensitivity and specificity. (stanford.edu)
  • Reliable and timely health information is essential for policy development, proper health management, evidence-based decision-making, rational resource allocation and monitoring and evaluation of the public health situation. (who.int)
  • This allows DNA methylation cancer biomarkers to be suitable for early detection and also to have utility across a range of areas relevant to cancer detection and treatment. (frontiersin.org)
  • The Secretariat is facilitating global surveillance of MERS-CoV for early detection of changes in the epidemiology of the virus and for investigation and reporting of cases, and it continues to make global risk assessments and information rapidly available through the Event Information Site for National IHR Focal Points, Disease Outbreak News, press releases and other reports. (who.int)
  • It is believed to be driven by changes in risk factors, early detection of cancer through CRC screening, and removal of precancerous polyps with colonoscopy, in addition to advances in surgical and treatment approaches. (lww.com)
  • RENEB maximizes the effort that can be deployed for early classification of individuals according to the received dose. (europa.eu)
  • Across the patient journey from initial detection, to treatment and then monitoring, there are several points where DNA methylation assays can inform clinical practice. (frontiersin.org)
  • High-dose oral treatment has proven to be as effective as the parenteral route, even in subjects with malabsorption, ensuring the complete resolution in the majority of cases. (mjhid.org)
  • These criteria are intended to guide radiologists, radiation oncologists and referring physicians in making decisions regarding radiologic imaging and treatment. (bvsalud.org)
  • These three methods of triplication should significantly increase the reliability of non-radiation hardened designs, which should allow commercial off-the-shelf (COTS) processing components to be used as flight critical hardware. (nasa.gov)
  • A European network of biological and physical-retrospective dosimetry "RENEB" has been set up which has the capacity and capability to significantly contribute to European Radiation Emergency Preparedness and to Radiation Protection Research in Europe. (europa.eu)
  • Digital imaging is a term that describes the presentation of a radiologic image on a computer monitor as a digital picture. (medscape.com)
  • At the same time, more data is required per wafer to generate higher order analyses while at the same time greater productivity in terms of silicon area processed in unit time is needed to keep the economics favorable. (spie.org)
  • As a result of this research, the proposed "International Center" can have one of its strategic scientific goals such as making prognosis, based on the data of global monitoring, of what new infections might emerge in the future. (biosecuritycommons.com)
  • This is higher than the efficacy (of source) of artificial lighting other than LEDs, which means using sunlight for illumination heats up a room less than fluorescent or incandescent lighting. (wikipedia.org)
  • While radiation tolerant devices will maintain an essential role in spacecraft design, having the cheaper and more state-of-the-art options of COTS products available and using this research to make them more palatable to the industry, will decrease satellite turn-around time in terms of the testing and specialized design knowledge required. (nasa.gov)
  • Two very perspective projects will be started soon in the field of development of fast and very sensitive PCR-microchip detection of dangerous pathogen genomes in blood and other biological samples. (biosecuritycommons.com)
  • The CDC practiced its activation protocols, exercised the establishment of its updated Incident Management System structure for radiation emergencies, and identified critical staffing needs for this type of response. (cdc.gov)
  • In 2006 the STFC Rutherford Appleton Laboratory began the development of the High Energy X-ray Imaging Technology (HEXITEC) detector system. (cern.ch)
  • Feature papers represent the most advanced research with significant potential for high impact in the field. (mdpi.com)
  • It benefits MELODI and EURADOS by providing capacity for radiation research and specialized biomarker development. (europa.eu)
  • In addition, RENEB contributes to the crosscutting topics "E&T" by providing inter-comparisons, specialized courses and seminars open also to non partners and to "Infrastructure" by acting as analysis platform for radiation emergency preparedness and radiation research. (europa.eu)
  • When direct solar radiation is not blocked by clouds, it is experienced as sunshine, a combination of bright light and radiant heat (Atmospheric). (wikipedia.org)
  • Here, we aim to provide an overview on the mechanisms of miRNA biogenesis and to discuss the functional impact of miRNAs on PCa under radiation response. (frontiersin.org)
  • High-intensity phototherapy first described by Tan in 1977 uses irradiance greater than 25 µW/cm 2 /nm up to 40 µW/cm 2 /nm when a dose-response relationship to bilirubin degradation reaches a plateau. (medscape.com)
  • Following the emergence of a novel coronavirus in 2012 (since named Middle East respiratory syndrome coronavirus (MERS-CoV)), the Secretariat has been working closely with Member States, National IHR Focal Points and partners to monitor and respond to the epidemic within the framework of the Regulations. (who.int)
  • In addition, many evidence-based nutritional interventions exist that may reduce the risk of developing colorectal cancer in those at high risk. (naturalmedicinejournal.com)
  • In addition to genetic syndromes and IBD, established risk factors include age, personal history of adenomas, family history of colorectal cancer, diets high in fat and low in fruit/vegetables, obesity, sedentary lifestyle, smoking, and excessive alcohol intake. (naturalmedicinejournal.com)
  • Such tests hold great promise for the development of simple, economical, and highly specific cancer detection tests suitable for population-wide screening, with several successfully translated examples already. (frontiersin.org)
  • The incidence of colorectal cancer is highest in Western populations. (naturalmedicinejournal.com)
  • Radiation damage suffered by the FI chips has had a negative impact on their energy resolution - the BI devices were not affected - thus affecting the basic considerations as to how to make best use of the instrument. (harvard.edu)
  • Another direct sensor is the high-density line-scan solid-state detector, which is lined by photostimulable barium fluorobromide "doped" with europium or caesium bromide phosphor. (medscape.com)
  • To meet these needs will require a new generation of detector technologies running at higher frame rates and making use of high-Z sensor materials. (cern.ch)
  • The distribution of particular person scores by criteria (Figure thirteen) exhibits a high dispersion of individual solutions for many criteria, except for illness frequency (but one outlier) and illness severity. (ehd.org)
  • The Advanced CCD Imaging Spectrometer (ACIS) offers the capability to simultaneously acquire high-resolution images and moderate resolution spectra. (harvard.edu)
  • Idea: Create a high fidelity simulation environment to practice everything from routine maintenance and managing time-sensitive emergencies for extracorporeal membrane oxygenation therapies. (clevelandclinic.org)
  • Furthermore, the detection of low levels of serum vitamin B12 appears poorly sensitive and specific. (mjhid.org)
  • Integrated metrology 2 , in-chip overlay control, advanced sampling and process correction-mechanism (using the highest order of correction possible with scanner interface today), are a few of such technologies considered in this publication. (spie.org)
  • Goa, India) and OptiMAL method for the health infrastructure coupled with political detection of pLDH (DiaMed, Cressier sur instability in malaria endemic countries, Morat, Switzerland) [ 10,12 ]. (who.int)
  • Use of this patch on the chest could improve detection of key markers of numerous harmful health conditions. (gatech.edu)
  • This will ensure the generation of more effective evidence to monitor improvement in the health situation, national y, regional y and global y. (who.int)
  • This comprehensive health profile is intended to serve as a tool to monitor progress in the health of the population. (who.int)
  • RENEB as analysis platform is of interest for the Emergency Preparedness Platform NERIS by adding preparedness in the field of individual dose estimation. (europa.eu)
  • Although consensus statements cannot replace high-certainty evidence, these can aid in the interpretation and dissemination of best practice from centres of excellence to the wider clinical community. (bvsalud.org)