Using randomly selected subsamples (Ns=200 and 60) of salivary analyte data collected as part of a larger epidemiologic study, we compute the rICCs for seven commonly assayed salivary measures in biobehavioral research - cortisol, alpha-amylase, c-reactive protein, interlekin-6, uric acid, secretory immunoglobulin A, and testosterone. (bvsalud.org)
How is mental health associated with adolescent alpha-amylase and cortisol reactivity and coordination? (researchgate.net)
Starches2
Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine, while the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the brush border of the small intestine. (drugs-library.com)
Only Old World primates known as ceropithecines have evolved AMY1 (salivary alpha-amylase) to consume starches from fruit seeds that they carry in their cheek pouches. (blogspot.com)
Salivary2
We explore the possibility that, due to advances in salivary assay precision, the contribution of laboratory-based measurement error in salivary analyte data is very small relative to more important and meaningful variability in analyte levels across biological replicates (i.e., between different specimens). (bvsalud.org)
However, with simulated gelada baboon gut, minimal changes were observed and this is consistent with animals without salivary amylase. (blogspot.com)
Consistent1
This is consistent with the low bioavailability of the parent drug. (drugs-library.com)
Cleavage2
The derivatives were reconverted to the parent compound (Cur) after cleavage of the ester bonds by microsomal esterase, indicating that the compounds could act as Cur prodrugs. (researchgate.net)
One metabolite (formed by cleavage of a glucose molecule from acarbose) also has alpha-glucosidase inhibitory activity. (drugs-library.com)
Compound3
Because acarbose acts locally within the gastrointestinal tract, this low systemic bioavailability of parent compound is therapeutically desired. (drugs-library.com)
This metabolite, together with the parent compound, recovered from the urine, accounts for less than 2% of the total administered dose. (drugs-library.com)
In contrast, less than 2% of an oral dose was recovered in the urine as active (that is, parent compound and active metabolite) drug. (drugs-library.com)
Children2
i.e., whether children are vulnerable to negative parenting styles (diathesis-stress) or, in addition to this vulnerability, also benefit more from positive parenting (differential susceptibility). (bvsalud.org)
A review of current approaches used to help children and parents cope with health care procedures. (mcmaster.ca)
Important1
There are two important points relative to analyzing data from this micro-data tape that should be noted: 1-Micro-data tape users should be fully aware of the importance of the 'patient visit weight' and how it must be used. (cdc.gov)
Data1
Most data tape users can obtain an adequate working knowledge of the relative standard error from the information presented in the Appendix. (cdc.gov)
Inhibitor5
Acarbose Tablets are an oral alpha-glucosidase inhibitor for use in the management of type 2 diabetes mellitus. (nih.gov)
To evaluate the relative potency of extracts and catechins, their concentrations required for 50 and 90% inhibition of enzyme activity were determined and compared to the widely used pharmacological glucosidase inhibitor, acarbose. (nih.gov)
Solution structure of the main alpha-amylase inhibitor from amaranth seeds. (lookformedical.com)
The most abundant alpha-amylase inhibitor (AAI) present in the seeds of Amaranthus hypochondriacus, a variety of the Mexican crop plant amaranth, is the smallest polypeptide (32 residues) known to inhibit alpha-amylase activity of insect larvae while leaving that of mammals unaffected. (lookformedical.com)
Structural comparison of the solution structure with the X-ray structure of the inhibitor when bound to its alpha-amylase target in Tenebrio molitor shows that the backbone conformation is only slightly adjusted on complexation, while that of the side chains involved in protein-protein contacts is similar to those present in solution. (lookformedical.com)
Inhibit1
The data show that plant extracts containing catechin 3-gallates, in particular epigallocatechin gallate, are potent inhibitors of α-glucosidase activity and suggest that procyanidins in grape seed extract strongly inhibit α-amylase activity. (nih.gov)
Pancreatic2
The antihyperglycemic action of acarbose results from a competitive, reversible inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucoside hydrolase enzymes. (nih.gov)
Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine, while the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the brush border of the small intestine. (nih.gov)
Enzymes1
PMID- 214397 TI - Influence of alpha-naphthylthiourea on blood glucose & some enzymes in albino rats. (nih.gov)
Activity5
One metabolite (formed by cleavage of a glucose molecule from acarbose) also has alpha-glucosidase inhibitory activity. (nih.gov)
Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity. (nih.gov)
This study evaluated the inhibitory effects of plant-based extracts (grape seed, green tea, and white tea) and their constituent flavan-3-ol monomers (catechins) on α-amylase and α-glucosidase activity, two key glucosidases required for starch digestion in humans. (nih.gov)
Results showed that grape seed extract strongly inhibited both α-amylase and α-glucosidase activity, with equal and much higher potency, respectively, than acarbose. (nih.gov)
Alpha-amylase is a biomarker of autonomic nervous system activity. (adxs.org)
Effect1
The effect of epinephrine on pseudofacility is due to alpha adrenergic stimulation. (nih.gov)
Results1
The results revealed that girls' high testosterone levels moderated the association between mothers' authoritarian parenting style and reactive aggression. (bvsalud.org)