Subsequent research was mainly focused mainly on the effects of inbreeding on human fertility, early morbidity and mortality, and the effects on quantitative biological traits [ 8 - 10 ]. (biomedcentral.com)
Unfortunately, these advances led to transmission of viral diseases including HIV and hepatitis, resulting in an increased burden of morbidity and mortality, especially during the 1980s. (interleukinreceptor.com)
Infant2
The effects of consanguinity on such parameters as fertility, infant and child development, mortality and morbidity are well known and havebeen studied in American 4 , Japanese 5 and Indian populations 6 . (org.pk)
Congenital anomalies or birth defects are among the leading causes of infant mortality and morbidity around the world. (biomedcentral.com)
Perinatal1
Perinatal malformation related mortality has recently been studied in Europeans and Pakistanis settled abroad 7-9 (Table). (org.pk)
Malformation1
No autopsy tal malformation and its relationship with examinations were performed on any in- consanguineous marriage in Kashan city, fants who died. (who.int)
Marriages2
3], but there is an impression that they are stetric history for any disease or medication more prevalent in populations with consan- during the recent pregnancy, consanguinity guineous marriages [4]. (who.int)
Secret marriages threatened not only parental authority but also class interests. (yivoencyclopedia.org)
Pedigree2
Parental consanguinity documenting pedigree analyzing, chromosome analysis and clinical examination were carried out for all cases. (who.int)
A Birmingham study proved that the relationship of parents significantly and adversely affected the child, the total prevalence of congenital malformations and handicap of 9% in the consanguineous group (mainly Pakistanis settled in the UK) as compared to 3% in the general population. (org.pk)
Populations1
The majority of this adverse effect happens in low- and middle-income countries (LMICs), with mortality rates being higher in rural and low-resource populations. (researchprotocols.org)
Clinical1
Conclusions -Early mortality is high in childhood dilated cardiomyopathy, but the clinical status of long-term survivors is good. (gotomydoctor.com)
High2
High hsCRP level was significantly associated with hypercholesterolemia (P = 0.001), age (P = 0.01), and mortality (0.04). (ac.ir)
Due to the high mortality rate among women during childbirth, it was not unusual for children to become orphaned or semiorphaned and integrated into new families with stepparents. (yivoencyclopedia.org)
Marriage4
familia ) is a group of people related either by consanguinity (by recognized birth) or affinity (by marriage or other relationship). (wikipedia.org)
in societies with a sexual division of labor, marriage , and the resulting relationship between two people, it is necessary for the formation of an economically productive household . (wikipedia.org)
To ensure that matchmaking remained under parental control, the Lithuanian Council decreed in 1623 that any marriage contracted without the knowledge of a father or close relative would be annulled. (yivoencyclopedia.org)
Anyone forced into marriage faces an increased risk of rape and sexual abuse as they may not consent, or may not be the legal age to consent to a sexual relationship. (safeguardingcambspeterborough.org.uk)
Effects2
The negative effects of parental consanguinity and inbreeding were studied in relationship with socioeconomic status and variability. (wikipedia.org)
In 1981, Schull and colleagues summarized thirty-four years of study on the genetic effects of the atomic bomb, followed by a series of papers on the causes of mortality of A-bomb survivors. (wikipedia.org)
Health1
The main objectives are to investigate the relationship of birth outcomes to both maternal and paternal preconception health and determine the effect of preconception care intervention on improvement of maternal nutritional status and reduction of the risk of adverse birth outcomes such as prematurity, low birth weight, and maternal and neonatal complications. (researchprotocols.org)
Higher1
A higher incidence may be encountered in cultures where parental consanguinity is common. (medscape.com)
Study1
on behalf of the National Australian Childhood Cardiomyopathy Study Background -Despite considerable mortality, population-based prognostic factors for childhood dilated cardiomyopathy are lacking. (gotomydoctor.com)
Impact1
We used logistic regression to assess the impact of parental age on the occurrence of cleft lip with or without cleft palate and cleft palate. (typeset.io)
Cardiologic evaluation should be done immediately in the case of RDS with treatment-resistant full-term newborn because a delay in the diagnosis increases operative mortality. (lupinepublishers.com)
The idiosyncratic relationship between diagnostic delay and stage of oral squamous cell carcinoma. (tractorgallery.net)
Morbidity7
NTM does not commonly cause disease, but under certain circumstances, these mycobacteria can cause serious morbidity and mortality. (medscape.com)
10] The increased rates of cardiovascular morbidity and mortality reinforce the close association between the syndromes. (medscape.com)
Birth defects are the main cause of mortality in infancy and represent an important source of morbidity at all ages, with a major proportion of cases being identified during pregnancy. (nature.com)
Whi le infections and malnutrition are the dominant causes of infant morbidity and mortality in the poorer countries, in the developed countries these causes are cancer, accidents and congenital malformations. (omjournal.org)
It is transmitted as an autosomal recessive gene characterized by recurrent chronic hemolytic anemia, vaso-occlusive crises, and predisposition to infections that seriously impact morbidity and mortality. (omjournal.org)
9 Generally, the care for patients with SCA has improved over the years due to earlier diagnosis, the widespread use of penicillin prophylaxis, vaccination, folate supplementation, and access to comprehensive care programs including blood transfusions and hydroxyurea therapy, impacting significantly on morbidity and mortality. (omjournal.org)
Indeed, patients with sub-optimal nutrition status are at increased risk of hospital admission and severe morbidity and mortality. (omjournal.org)
METHODS: The 2019 Global Burden of Disease database was searched to collect incident cases/incidence and deaths/mortality of neonatal jaundice, as well as global socio-demographic index (SDI) and universal health coverage index (UHCI). (bvsalud.org)
The correlations between incidence/mortality of neonatal jaundice and SDI and UHCI were evaluated. (bvsalud.org)
Chromosome2
Parental consanguinity documenting pedigree analyzing, chromosome analysis and clinical examination were carried out for all cases. (who.int)
Parental consanguinity is not uncommon in children with developmental problems in our study population, and can be identified by use of a combined CGH and SNP chromosome microarray. (biomedcentral.com)
Developmental2
However, the frequency of parental consanguinity in children with developmental disabilities is unknown, and consanguineous couples may not be identified during doctor's visit or genetic counseling without microarray. (biomedcentral.com)
Here we report our study results on patients referred for developmental problems using a combined CGH/SNP array with a focus on detection of parental consanguinity. (biomedcentral.com)
Proportion3
A reciprocal relationship between the fitness effect of a mutation and the proportion of de novo mutations (DNMs) is observed in a dominantly inherited disorder. (nature.com)
The Kaplan Meier proportion for mortality (90% CI) at 10 and 24 weeks for AMB was 17% (10, 29) and 24% (15, 37), compared to 20% (12, 32) and 30% (20, 43) for 1600mg, and 33% (23, 46) and 38% (27, 51) for 2000mg/day FCZ. (bvsalud.org)
10 In developed countries such as the United Kingdom, CM account for a substantial proportion (26-34%) of perinatal mortality. (omjournal.org)
Genetic3
In 1981, Schull and colleagues summarized thirty-four years of study on the genetic effects of the atomic bomb, followed by a series of papers on the causes of mortality of A-bomb survivors. (wikipedia.org)
The present patient was an immunocompetent, previously healthy woman without known parental consanguinity or genetic disorders. (medscape.com)
Genetic effects of consanguinity can be traced to the fact that the inbred individual may carry two copies of a gene that was present in a single copy in the common ancestor of his/her consanguineous parents. (omjournal.org)
Birth defects1
Consanguinity is associated with an increased risk of birth defects and autosomal recessive disorders. (biomedcentral.com)
Cases2
Identification of parental consanguinity in such cases can be important for further diagnostic testing. (biomedcentral.com)
Our results suggested presence of parental consanguinity in 21 cases (3.46%) including 4 (3.07%) from Brazil and 17 (3.56%) referred from hospitals in south Florida (Table 1 ). (biomedcentral.com)
Social1
Consanguinity has been a long standing social habit among some Iranians. (omjournal.org)
Effect1
2023. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. (edu.qa)