Cell AgingAxin Signaling ComplexPhenotypeDNA DamageFibroblastsInterleukin-6Cells, CulturedEpithelial CellsSignal TransductionMutationMolecular Sequence DataGenotypeBase SequenceAmino Acid SequenceAllelesCell DifferentiationMice, Inbred C57BLMice, KnockoutPedigreeGenetic Complementation TestMice, TransgenicChromosome MappingGene DeletionTranscription FactorsRNA, MessengerCell LineImmunophenotypingCrosses, GeneticGene Expression Regulation, DevelopmentalDisease Models, AnimalHomozygote