Ubiquitin-Protein LigasesUbiquitinUbiquitinsLigasesAngelman SyndromeUbiquitin-Conjugating EnzymesUbiquitin-Protein Ligase ComplexesUbiquitinationEndosomal Sorting Complexes Required for TransportProteasome Endopeptidase ComplexCullin ProteinsAnaphase-Promoting Complex-CyclosomeSKP Cullin F-Box Protein LigasesMolecular Sequence DataAmino Acid SequenceCarbon-Nitrogen LigasesProtein BindingF-Box ProteinsMutationPolyubiquitinUbiquitin-Activating EnzymesFatty Acid Synthase, Type IIS-Phase Kinase-Associated ProteinsBiotinylationRNA Ligase (ATP)Substrate SpecificityUbiquitin ThiolesteraseCell LineCell Cycle ProteinsSaccharomyces cerevisiae ProteinsSequence Homology, Amino AcidProtein Structure, Tertiarybeta-Transducin Repeat-Containing ProteinsBiotinSaccharomyces cerevisiaeF-Box MotifsPeptide SynthasesProteolysisBase SequenceCarrier ProteinsRepressor ProteinsMultienzyme ComplexesProtein Processing, Post-TranslationalIron Regulatory Protein 1Thioctic AcidCysteine EndopeptidasesTranscription FactorsRecombinant Fusion ProteinsHeLa CellsIron Regulatory Protein 2Acetyl-CoA CarboxylaseDNA LigasesHydroxyapatitesMultiprotein ComplexesDNA-Binding ProteinsProteinsVon Hippel-Lindau Tumor Suppressor ProteinBacterial ProteinsInhibitor of Apoptosis ProteinsHEK293 CellsTwo-Hybrid System TechniquesAdenovirus E4 ProteinsModels, MolecularEscherichia coliAmino Acid MotifsLeucine-Responsive Regulatory ProteinRecombinant ProteinsRING Finger DomainsNuclear ProteinsProtein StabilityPolynucleotide LigasesSignal TransductionBinding SitesImmunoprecipitationEscherichia coli ProteinsCloning, MolecularUbiquitin CIron-Regulatory ProteinsModels, BiologicalTranscription, GeneticPhosphorylationRNA InterferenceCell CycleTransfectionAdaptor Proteins, Signal TransducingElectrophoresis, Polyacrylamide GelRNA, Small InterferingGene Expression RegulationProtein TransportCell Line, Tumorvif Gene Products, Human Immunodeficiency VirusViral Regulatory and Accessory ProteinsIntracellular Signaling Peptides and ProteinsTumor Suppressor ProteinsImmunoblottingRNA, MessengerProto-Oncogene Proteins c-cblCyclin-Dependent Kinase Inhibitor ProteinsGlutamate-Cysteine LigaseSequence Alignment