X-Linked Inhibitor of Apoptosis ProteinInhibitor of Apoptosis ProteinsApoptosisCaspasesCaspase 3Caspase InhibitorsApoptosis Regulatory ProteinsCaspase 9Proto-Oncogene Proteins c-bcl-2Cell Line, TumorMicrotubule-Associated ProteinsCaspase 7Neoplasm Proteinsbcl-2-Associated X ProteinCell SurvivalMitochondrial ProteinsProteinsDNA FragmentationIn Situ Nick-End LabelingSignal TransductionApoptotic Protease-Activating Factor 1Neuronal Apoptosis-Inhibitory ProteinCytochromes cEnzyme ActivationCaspase 8TNF-Related Apoptosis-Inducing LigandMitochondriaCASP8 and FADD-Like Apoptosis Regulating Proteinbcl-X ProteinIntracellular Signaling Peptides and ProteinsDown-RegulationTumor Cells, CulturedCells, CulturedAntineoplastic AgentsCell ProliferationBlotting, WesternFas Ligand ProteinCell LineNF-kappa BCysteine Proteinase InhibitorsTumor Suppressor Protein p53RNA, Small InterferingApoptosis Inducing FactorCarrier ProteinsTransfectionTumor Necrosis Factor-alphaFlow CytometryCell CycleGene Expression Regulation, NeoplasticDrug Resistance, NeoplasmReverse Transcriptase Polymerase Chain ReactionPoly(ADP-ribose) PolymerasesHeLa CellsApoptosomesUp-RegulationEnzyme InhibitorsProto-Oncogene Proteins c-aktRNA, MessengerCell DeathRNA InterferenceJurkat CellsPhysical PhenomenaProto-Oncogene ProteinsBH3 Interacting Domain Death Agonist ProteinCell DivisionDose-Response Relationship, DrugMembrane Potential, MitochondrialImmunohistochemistryBiomimetic MaterialsAnnexin A5Molecular Sequence DataPhosphorylationMembrane GlycoproteinsCytochrome c Groupbcl-Associated Death ProteinAzocinesModels, BiologicalAdaptor Proteins, Signal TransducingTime FactorsDrug SynergismUbiquitinImmunoblottingAmino Acid SequenceAmino Acid Chloromethyl KetonesAntineoplastic Agents, PhytogenicProtein BindingOligopeptidesProteasome Endopeptidase ComplexMitochondrial MembranesTNF Receptor-Associated Factor 1Mice, Inbred C57BLCaspase 6UbiquitinationReceptors, TNF-Related Apoptosis-Inducing LigandGene Expression RegulationHCT116 CellsXenograft Model Antitumor AssaysMice, KnockoutReceptors, Tumor Necrosis FactorProtein Structure, Tertiary