Regulation of gene expression in eukaryotes. Medical search. Frequent questions

Molecular Biology: Advanced Topics in Eukaryotes (Ba3 - BSc in Molecular Biotechnology): this course aims at confronting the student with the fundamental principles of molecular biology in prokaryotes and eukaryotes and zooms in on the structure-function relationship of DNA and chromosomes with regards to replication, transcription, translation and gene regulation. (ugent.be)
This module will provide appropriate grounding regarding the structure of proteins, how this relates to their function and the mechanisms responsible for the regulation of gene expression in prokaryotes and eukaryotes. (le.ac.uk)
Thus, arrest peptides are used for metabolite-dependent gene regulation in both prokaryotes and eukaryotes. (u-bordeaux.fr)

In higher eukaryotes DNA methylation acts as another method for the regulation of gene expression (Costello and Plass, 2001). (thermofisher.com)
Oxr1p belongs to the group of TLDc domain containing proteins that are highly conserved in higher eukaryotes. (upstate.edu)

However, the mechanisms underlying these variations and their phenotypic expression are unclear. (nature.com)
Our group is interested in the mechanisms that control gene expression from very early to very late in human life. (unibas.ch)
We are interested primarily in mechanisms of post-transcriptional gene expression control, involving small non-coding RNAs and RNA-binding proteins. (unibas.ch)
The Goodell Lab focuses on the basic mechanisms that regulate hematopoietic stem (HSC) cells, and how their mis-regulation leads to leukemia development. (chicagobiomedicalconsortium.org)
6/2013 School Award - Joerg Braun, a postdoctoral associate, was awarded the Otto Hahn Medal for his outstanding PhD work on the mechanisms of miRNA-mediated gene silencing from the Max Planck Institute. (umassmed.edu)
Increasing evidence now suggests a major role for epigenetic mechanisms in gene expression in the parasite. (biorxiv.org)
In the Course of Genetics, the student will learn the genetic mechanisms at the bases of Mendelian genetics, the main molecular aspects of the Central Dogma, how genes work, with emphasis on the relationship between the type of mutation and the resulting phenotype, and last the models for the study of evolutionary processes. (uninsubria.eu)
The learning outcomes, in terms of "Knowledge and know" are: achievement of informed judgment, adequate expertise and communication skills in relation to the genetic mechanisms at the bases of Mendelian genetics, molecular aspects of DNA replication, of transcription and translation, gene function, evolutionary processes and the theoretical and practical bases of recombinant DNA technology. (uninsubria.eu)
This description was satisfactory inasmuch as the intricate pathways of metabolism and, later, the basic mechanisms of gene regulation and signal transduction were still being unraveled. (berkeley.edu)
While significant advances have been made in understanding the plant adaptation in stress environments, there are still challenges to translate this acquired knowledge for improved crop performance and productivity under stress environments due to complex genetics involving multitude of genes and stress tolerance mechanisms and interaction with numerous environmental factors pose. (eurekaselect.com)
Elucidating the mechanisms controlling gene expression is important to the understanding of human health. (pressbooks.pub)
RATIONALE: Post-translational modification of histone proteins are major mechanisms that modify chromatin structure and regulate gene expression in eukaryotes. (cdc.gov)
Molecular mechanisms for regulation of gene expression at different levels: remodeling of chromatin, initiation of transcription, nuclear transport and signalling, and RNA interference. (lu.se)
Streptococcal pathogens continue to evade concerted efforts to decipher clear-cut virulence mechanisms, although numerous genes have been implicated in pathogenesis. (cdc.gov)

What features of eukaryotes provide additional opportunities for the regulation of gene expression compared to bacteria? (pearson.com)
The Khan Academy has an educational unit on gene regulation , including videos about gene regulation in bacteria and eukaryotes. (medlineplus.gov)
A comprehensive method for amplicon-based and metagenomic characterization of viruses, bacteria, and eukaryotes in freshwater samples. (cdc.gov)

citation needed] In eukaryotes, the spliceosome performs the splicing reactions essential for removing intron sequences, this process is required for the formation of mature mRNA. (wikipedia.org)
Gene regulation can occur at any point during gene expression, but most commonly occurs at the level of transcription (when the information in a gene's DNA is passed to mRNA). (medlineplus.gov)
Messenger RNA (mRNA) molecules are encoded by genes and are themselves templates for the proteins that carry the main metabolic functions in a cell. (sciencedaily.com)
The complex then cleaves the mRNA into smaller pieces, thereby preventing translation of the protein it encodes, and thus inhibiting or "silencing" gene expression. (sciencedaily.com)
The plants showed increased accumulation of ARF17 mRNA and altered levels of mRNAs corresponding to several genes that may be regulated by ARF17. (sciencedaily.com)
Dr. Bellini and her colleagues found that the mutant plants over-accumulate ARF17 mRNA within the hypocotyl, pointing to ARF17 as a major regulator of adventitious rooting and microRNA-mediated regulation as a major regulator of ARF17. (sciencedaily.com)
Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis. (us.es)
The function of RNA Polymerase II (Pol2) is essential for eukaryotes as it transcribes all cellular mRNA. (uni-wuerzburg.de)
Subsequently, we detected the expression of EZH2 on mRNA level and protein level in two different embryonic development stages (65-dpc and 90-dpc) via qRT-PCR and western blots. (hindawi.com)

Another ubiquitous RNP called SRP recognizes and transports specific nascent proteins to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes. (wikipedia.org)
We have learned that genes in mammalian cells are transcribed into messenger RNAs (mRNAs), which are to be translated into polypeptides (proteins). (intechopen.com)
These proteins bind to regulatory regions of a gene and increase or decrease the level of transcription. (medlineplus.gov)
Polycomb Group (PcG) of proteins compact chromatin keeping genes in a repressed state. (chicagobiomedicalconsortium.org)
Research reported in The Plant Cell shows that microRNAs control the accumulation of transcription factor proteins that regulate the expression of genes in the auxin response pathway. (sciencedaily.com)
There are many AGO1-like proteins in animals and other eukaryotes as well, indicating that the RNA-induced silencing complex is of ancient evolutionary origin, and that microRNA-mediated regulation of gene expression is shared among many eukaryotes. (sciencedaily.com)
Mechanically, m6A can be recognized by "reader" proteins or can directly modify RNA conformation, and it widely affects gene expression by mediating RNA stability, translation, splicing and export. (scienceopen.com)
Whereas regulating gene expression in multicellular organisms allows for cellular differentiation, in single-celled organisms like prokaryotes, it primarily ensures that a cell's resources are not wasted making proteins that the cell does not need at that time. (pressbooks.pub)
Polycomb Group (PcG) proteins are a family of protein complex that regulate gene expression, especially repressing gene transcription [ 1 ]. (hindawi.com)
Alternative splicing of gene can generate multiple transcripts and proteins to regulate tissue and organ development [ 17 ]. (hindawi.com)

Students will understand the basis of genome maintenance and gene expression, and appreciate the concept of mutation at the level of the genotype and how this manifests at the phenotypic level. (manchester.ac.uk)
The National Human Genome Research Institute provides a definition of gene regulation in their Talking Glossary of Genetic Terms. (medlineplus.gov)
Collectively, these maps provide a high-resolution view of 3D maize genome architecture, and its role in gene expression and phenotypic variation. (nature.com)
Accordingly, three-dimensional genome architecture models at various resolutions, based on chromatin interactomes, have provided a conceptual framework for transcriptional regulation in animals ranging from flies to humans 12 . (nature.com)
By integrating expression quantitative trait locus (eQTL) and genome-wide association study (GWAS) data, we demonstrate that long-range chromatin interactions between variant regulatory elements and their target genes contribute to variations in gene expression, metabolic phenotypes, and agronomic traits. (nature.com)
Topics covered will include cell membrane structure and function, metabolism, cell motility and division, genome structure and replication, the regulation of gene expression and protein production, genotype to phenotype relationship, and basic principles of inheritance. (middlebury.edu)
In this study, we first identified all the CAMTA homologous genes in the whole genome of maize. (frontiersin.org)
In eukaryotes, many lncRNAs have been identified and shown to be pivotal regulators of genome structure and gene expression. (biorxiv.org)
ChIRP-seq of candidate lncRNAs revealed that lncRNA occupancy sites within the parasite genome are focal and sequence-specific with a particular enrichment for several parasite-specific gene families, including those involved in pathogenesis, erythrocyte remodeling, and regulation of sexual differentiation. (biorxiv.org)
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. (nature.com)
Eukaryotic genome organization and regulation of gene expression, transposable elements. (inspirenignite.com)
Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species. (cdc.gov)

Genomic DNA contains both structural gene s, which encode products that serve as cellular structures or enzymes, and regulatory gene s, which encode products that regulate gene expression. (pressbooks.pub)
Three types of epigenetic modification that regulate gene expression in mammalian cells. (nationaljewish.org)

The H/ACA box and C/D box snoRNAs are ncRNAs found in archaea and eukaryotes. (wikipedia.org)

In prokaryotes, and specially in eukaryotes, replication and transcription regulation involve the interaction of many specialized protein factors at regulator locations on the sequence to ensure correct sequence recognition, initiation, processivity, fidelity, and kinetic control. (berkeley.edu)
Each histone subtype has several copies of the same gene to allow for the large demand placed during DNA replication. (news-medical.net)
Histones can be classified as replication dependent or replication independent, which is decided by their expression pattern during the cell cycle. (news-medical.net)
The replication independent histone genes are transcribed at a relatively constant low rate, regardless of cell cycle stage. (news-medical.net)
However, most of the vertebrate histone genes are replication dependent and are therefore more highly expressed during the cell cycle's S phase. (news-medical.net)
Given that the replication dependent histone genes all activate upon entry into the S phase, it is speculated that there exists some further upstream regulatory element. (news-medical.net)

In addition to RNA-associated silencing and histone modification, a major epigenetic mechanism in higher-order eukaryotes is DNA methylation. (qiagen.com)
Epigenetic changes play a crucial role in the regulation of important cellular processes, such as gene expression and cellular differentiation, and were also identified as key factors in various diseases. (qiagen.com)
A) Methylation of DNA cytosine residues at the carbon 5 position (5 me C) is a common epigenetic mark in many eukaryotes and is most often found in CpG sequence context. (nationaljewish.org)

As one of the two distinct complexes, namely, Polycomb Repressive Complex 1 (PRC1) and PRC2, PRC2 mediates gene silencing by modulating chromatin structure [ 2 ]. (hindawi.com)

Chromatin loops connect regulatory elements to their target genes. (nature.com)
However, spatial organization of regulatory elements and its impact on gene expression in plants remain unclear. (nature.com)
The maps indicate that chromatin loops are formed between regulatory elements, and that gene pairs between promoter proximal regions tend to be co-expressed. (nature.com)
In eukaryotes, cis regulatory elements and associated trans -acting factors regulate spatiotemporal gene expression, which affects individual development. (nature.com)
However, due to the limited resolution of Hi-C maps, comprehensive high-resolution chromatin maps involving regulatory elements, which allow for elucidation of their impact on transcriptional regulation are still lacking in plants. (nature.com)
In this study, we explore the regulatory role of mutations occurring in distal regulatory elements related to gene expression and phenotypic variations with adapted long-read ChIA-PET, and construct high-resolution chromatin interaction maps of maize promoter proximal regions and distal regulatory elements associated with RNA polymerase II occupancy and histone mark H3K4me3. (nature.com)
Our results highlight the significance of 3D organization of regulatory elements and suggest that the topology of long-range genetic variations may affect gene expression as well as phenotype variation. (nature.com)
They are usually clustered around the regulatory region of genes and can affect their transcriptional regulation. (qiagen.com)
mRNAs corresponding to several regulatory genes that mediate auxin responses contain short stretches of sequence that are complementary to microRNAs, and therefore have been considered potential targets of microRNA-mediated regulation. (sciencedaily.com)
We then surveyed the distribution of stress-related cis -regulatory elements in the −1.5 kb promoter regions of ZmCAMTA genes. (frontiersin.org)
the cell may regulate the transcription of individual genes through regulatory molecules (ex. (powershow.com)
One or more transcription factors activate transcription by binding to cis-regulatory sites, which are commonly situated upstream of protein-coding genes. (nationaljewish.org)

CAMTAs participate in gene expression regulation by binding to the cis -elements in the promoter regions of numerous target genes. (frontiersin.org)

The Genetic Science Learning Center at the University of Utah offers an explanation of gene expression as it relates to disease risk . (medlineplus.gov)
Through lectures, laboratory classes, tutorials and computer-based practical classes, this module will give you a thorough understanding of molecular aspects of the expression and regulation of genetic information in living cells. (le.ac.uk)
Notably, a large number of stress-related elements present in the promoter regions of some ZmCAMTA genes, indicating a genetic basis of stress expression regulation of these genes. (frontiersin.org)
The effects of mutation, gene flow, selection and genetic drift on the gene pool. (uninsubria.eu)
An approach to the regulation of field trials, known as the "Stanford Model," is designed to assess risks of new agricultural introductions, whether or not the organisms are genetically engineered, and independent of the genetic modification techniques employed. (eurekaselect.com)
Basic Principles of inheritance, molecular basis of heredity, sex determination and sex-linked characteristics, cytoplasmic inheritance, linkage, recombination and mapping of genes in eukaryotes, population genetics, genetic disorders, roles of model organisms in understanding genetic principles. (inspirenignite.com)
You will study the structure of DNA and chromatin, and develop an understanding for how the expression of genetic information is regulated. (lu.se)
Gene technology: basic and applied molecular genetic methods. (lu.se)

To provide a general introduction to the molecular basis of genetics, how genes are maintained from one generation to the next and how their expression is regulated in various systems. (manchester.ac.uk)
The latest schedule for the course Molecular Genetics of Eukaryotes in the schedule software TimeEdit. (lu.se)

An important aim is to bring insight into gene structure, recombination, gene expression and gene regulation, including the differences between pro-and eukaryotes. (ugent.be)

They serve as bridges between transcriptional regulation and phenotypic variation in mammals. (nature.com)
In the future, the core promoter will be an integral part of all analyses of transcriptional regulation. (grantome.com)

Gene mutations: missense versus nonsense mutations, insertions, deletions and frameshifts. (manchester.ac.uk)
Analysis of GFM1 gene mutations in a family with combined oxidative phosphorylation deficiency 1]. (nih.gov)
Gene mutations: their rate and their molecular basis. (uninsubria.eu)

From DNA to RNA: the structure and function of the gene, promoters and terminators. (manchester.ac.uk)
When located at gene promoters, DNA methylation is usually association with repression of gene expression. (nationaljewish.org)

QIAseq Targeted Methyl Panels deliver high mapping efficiency (figure QIAseq Targeted Methyl Panel: mapping efficiency Input >1 ng – gDNA – FFPE – ccfDNA Results show high mapping on primer and high unique mapping. "> QIAseq Targeted Methyl Panel: mapping efficiency ), high reproducibility (figure QIAseq Targeted Methyl Panel: methylation degree reproducibility To test methylation degree accuracy and reproducibility, 40 ng control DNA with 0%, 50% and 100% methylation were processed using the QIAseq Targeted Methyl Panel, which consisted of 749 primers. Samples were sequenced on MiSeq and methylation degree of CpG covered by >30 UMI was evaluated, resulting in accurate and highly reproducible methylation calling. "> QIAseq Targeted Methyl Panel: methylation degree reproducibility ) and high correlation with established methods (figures QIAseq Targeted Methyl Panel - high correlation with established methods To test correlation with established methods, the QIAseq Targeted Methyl Panel was used with 40 ng input gDNA from hepatocytes. The panel consisted of 102 primers, covering 71 CpGs. Compared to the Supplier I array, methylation degree resulted in high correlation. "> QIAseq Targeted Methyl Panel - high correlation with established methods and QIAseq Targeted Methyl Panel: methylation status of FFPE DNA: methylation degree To test methylation status of FFPE DNA, the QIAseq Targeted Methyl Panel was used with 40 ng input FFPE DNA. The panel consisting of 93 primers covered 566 CpG sites. The evaluated methylation degree of 7 CpG sites of the MGMT gene highly correlates to the methylation degree that was previously validated with Pyrosequencing. "> QIAseq Targeted Methyl Panel: methylation status of FFPE DNA: methylation degree ). (qiagen.com)
Methylation of CpG islands is known to inactivate gene expression and plays an important role in normal and disease development. (qiagen.com)
1997). DNA methylation has also been shown to play a central role in gene imprinting, embryonic development, x-chromosome gene silencing, and cell cycle regulation. (thermofisher.com)
PCR2 targets genes that are developmentally regulated and catalyzes di- and histone tri-methylation, resulting in chromatin compaction and gene repression. (chicagobiomedicalconsortium.org)

This gene encodes one of the mitochondrial translation elongation factors. (nih.gov)
however, gene expression in eukaryotes is more complicated because of the temporal and spatial separation between the processes of transcription and translation. (pressbooks.pub)

These results validated a different transcript in pigs and characterized its expression profile in fetal tissues of different gestation stages, which indicated that EZH2 played important roles during porcine embryonic development. (hindawi.com)
In the early embryonic development, abnormal expression of EZH2 impaired embryo growth and pluripotency maintenance [ 7 , 8 ]. (hindawi.com)
Thus, the appropriate expression level of the EZH2 gene is important for embryonic development. (hindawi.com)
In pigs, several studies have focused on its function in early embryonic development regulation and in SCNT efficiency improvement [ 8 , 14 - 16 ]. (hindawi.com)
However, the transcript and expression status of the EZH2 gene during porcine embryonic development remains unknown. (hindawi.com)

Thus, although most regulation of gene expression occurs through transcriptional control in prokaryotes, regulation of gene expression in eukaryotes occurs at the transcriptional level and post-transcriptionally (after the primary transcript has been made). (pressbooks.pub)
However, the transcript variant and temporal expression pattern of EZH2 in the middle and late porcine fetus are still unknown. (hindawi.com)

MicroRNAs are tiny ribonucleic acid (RNA) molecules (~22 nucleotides long) that recently have been found to play important roles in regulating gene expression in eukaryotic organisms, including plants and animals. (sciencedaily.com)

To this end, we develop models to explain various properties of RNAs, such as the usage of specific processing sites or the expression level of individual isoforms in terms of the combination of binding sites that these RNAs have for various regulators. (unibas.ch)

For example, in E. coli , all of the structural genes that encode enzymes needed to use lactose as an energy source lie next to each other in the lactose (or lac ) operon under the control of a single promoter, the lac promoter. (pressbooks.pub)

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. (nih.gov)
There, he chose to tackle what was, at the time, a little-known form of translational control: the regulation of ribosomal protein synthesis by the nascent polypeptide. (u-bordeaux.fr)
Regulation of transcription and the correct succession of Pol2 in the transcriptional cycle is critically determined by post-translational modifications. (uni-wuerzburg.de)
Translational regulation in prokaryotes. (schoolnova.org)

The main mammalian histone subtypes ( H2A, H2B, H3, and H4 ) and the linker H1 are located in different gene clusters. (news-medical.net)

The more conserved ncRNAs are thought to be molecular fossils or relics from the last universal common ancestor and the RNA world, and their current roles remain mostly in regulation of information flow from DNA to protein. (wikipedia.org)
Molecular Biology introduces you to the structure and function of molecules, including DNA and RNA, which allow genes to be expressed and be maintained from one generation to the next. (manchester.ac.uk)
En: Methods in Molecular Biology. (us.es)
Because the course includes a major practical part, you will gain experience of molecular biology techniques for the analysis of gene structure and function. (lu.se)

Auxin influences development by affecting the expression of numerous genes that control the processes of cell division and cell expansion in specific plant tissues at specific stages during the plant life cycle - e.g. for leaves, roots, and floral organs to develop in the correct patterns and correct time sequence. (sciencedaily.com)

Interestingly, the 2-MIB synthesis gene was consistently expressed, regardless of the water temperature. (mdpi.com)

In this way, regulation of the transcription of all of the structural genes encoding the enzymes that catalyze the many steps in a single biochemical pathway can be controlled simultaneously, because they will either all be needed at the same time, or none will be needed. (pressbooks.pub)

In other words, expression of specific genes might have relevance to pathogenesis of diseases. (intechopen.com)

Interaction between different genes. (uninsubria.eu)
Understanding the interaction between the gene expression of a pathogen and that of its human host is important for the understanding of a particular infectious disease. (pressbooks.pub)

The internal N6-methyladenosine (m6A) modification in messenger RNA is one of the most abundant RNA modifications in eukaryotes. (chicagobiomedicalconsortium.org)
N6-methyladenosine (m6A) is the most abundant inner RNA modification in eukaryotes. (scienceopen.com)

Recent global analyses of gene transcripts revealed that specific transcription factors (TFs) and their networking systems physiologically correspond to the onset of human diseases, including cancer. (intechopen.com)
Functional analyses indicated that some of the genes induced by dragonfly larvae caused an increase in laminins necessary for cell adhesion in the extracellular matrix. (biomedcentral.com)
Methods for analysis of gene expression: microarray, hybridisation, promoter analyses. (lu.se)

The complex life cycle of Plasmodium falciparum requires coordinated gene expression regulation to allow host cell invasion, transmission, and immune evasion. (biorxiv.org)

The graduate programs offered by the Centre for Biotechnology encompass the broad fields of chemical and gene biotechnology. (brocku.ca)
Gene biotechnology involves the use of DNA technology, bioinformatics and microbiological techniques to study biological phenomena. (brocku.ca)

Furthermore, the decreased expression of the EZH2 gene is crucial for stem cell differentiation into specific cell lineages involved in myogenesis, adipogenesis, osteogenesis, neurogenesis, and haematopoiesis [ 9 ]. (hindawi.com)

These modifications lead to either repression or enhancement of gene expression. (nationaljewish.org)

Furthermore, the expression pattern of ZmCAMTA genes under RBSDV infection was analyzed to investigate their potential roles in responses of different maize cultivated varieties to RBSDV. (frontiersin.org)

Gene regulation involves a complex web of interactions within a given cell among signals from the cell's environment, signalling molecules within the cell, and the cell's DNA. (pressbooks.pub)

Several genes involved in different aspects of stem cell activation are being studied, including some that transduce initial signals, and others that regulate self-renewal and differentiation. (chicagobiomedicalconsortium.org)
A cyclin E-CDK2 substrate called NPAT has been found to be associated with histone gene clusters, and cyclin E-CDK2 bolsters activation of histone gene transcription by NPAT. (news-medical.net)
Histone deacetylase and acetyltransferase inhibitors decrease organic dust-mediated activation of proinflammatory gene expression. (cdc.gov)

In eukaryotes, DNA is packaged as chromatin, which acts as a barrier between the transcription machinery and genomic material. (pitt.edu)

A recent study from the Wilkens lab in collaboration with Seoul National University uncovered a novel mechanism of yeast V-ATPase regulation based on biochemical experiments and cryo electron microscopy (cryo-EM) structures of holo V-ATPase and Oxr1 bound V 1 subcomplex. (upstate.edu)

The maps also demonstrated the topological basis of quantitative trait loci which influence gene expression and phenotype. (nature.com)
Quantitative real-time PCR was used to test the expression of ZmCAMTA genes under several abiotic stresses (drought, salt, and cold), various stress-related hormones [abscisic acid, auxin, salicylic acid (SA), and jasmonic acid] and biotic stress [rice black-streaked dwarf virus (RBSDV) infection]. (frontiersin.org)

Genes and alleles, phenotype and genotype. (uninsubria.eu)

Genes are turned on and off in different patterns during development to make a brain cell look and act different from a liver cell or a muscle cell, for example. (medlineplus.gov)
The results showed that nine ZmCAMTA genes showed highly diversified gene structures and tissue-specific expression patterns. (frontiersin.org)
Silencing the m(6)A methyltransferase significantly affects gene expression and alternative splicing patterns, resulting in modulation of the p53 (also known as TP53) signalling pathway and apoptosis. (scienceopen.com)

The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene. (wikipedia.org)
Epigenetics describes the study of heritable changes in gene function that occur without a change in the nuclear DNA sequence. (qiagen.com)
Here, we identified the coding sequence of the EZH2 gene and characterized its expression pattern in fetal tissues of Duroc pigs at 65- and 90-day postcoitus (dpc). (hindawi.com)
Complete sequence of an IncFII plasmid harbouring the colistin resistance gene mcr-1 isolated from Belgian pig farms. (cdc.gov)

We are studying the structural basis of protein-DNA interactions and their relevance in the processes of control of gene expression using single molecule manipulation methods. (berkeley.edu)

Using nascent RNA expression profiles, we identified a total of 1,768 lncRNAs, of which 58% were identified as novel lncRNAs in P. falciparum . (biorxiv.org)

Each cell expresses, or turns on, only a fraction of its genes at any given time. (medlineplus.gov)
Your second year builds on this knowledge and covers areas such as gene regulation, cell biology and metabolism. (kent.ac.uk)
In both cases, each genetically identical cell does not turn on, or express, the same set of genes. (pressbooks.pub)
Upregulation of histone gene expression is one of the hallmarks of entry into the cell cycle's S phase. (news-medical.net)
Therefore, NPAT could be the link between cell cycle machinery and shared heightened transcription of histone genes during S phase. (news-medical.net)
Gene regulation in developmental biology and the cell cycle. (lu.se)

New Facets in Mycobacterium and Malaria parasite biology, Regulation of gene expression. (infinitecourses.com)

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation. (us.es)

The current approach to regulation, which captures organisms to be field tested or commercialized according to the techniques used to construct them rather than their properties, flies in the face of scientific consensus. (eurekaselect.com)
Strategies for gene therapy and production of medicines via genetically-modified organisms (expression vectors and viral vectors). (lu.se)

Anatomy19

Organisms27

Diseases1

Chemicals and Drugs65

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Phenomena and Processes108

Disciplines and Occupations3

Technology, Industry, Agriculture1

Information Science8

Health Care2

Prokaryotes and eukaryotes3

Higher eukaryotes2

Mechanisms14

Bacteria3

MRNA9

Proteins10

Genome12

Regulate gene expression2

Archaea1

Replication6

Epigenetic3

Chromatin structure1

Regulatory12

Target genes1

Genetic8

Genetics2

Recombination1

Transcriptional regulation2

Mutations3

Promoters2

Methylation4

Translation2

Embryonic development5

Transcript2

Eukaryotic1

RNAs1

Operon1

Translational4

Mammalian1

Molecular4

Numerous genes1

Synthesis1

Structural genes1

Pathogenesis1

Interaction2

Modification2

Analyses3

Plasmodium1

Biotechnology2

Stem cell differenti1

Repression1

Roles1

Molecules1

Activation3

Genomic1

Yeast1

Quantitative2

Alleles1

Patterns3

Sequence4

Manipulation1

Nascent1

Cell6

Biology1

Ribosome1

Organisms2