Cell AgingCell CycleCell Cycle ProteinsGenes, cdcCyclin-Dependent Kinase Inhibitor p16Cyclin-Dependent Kinase Inhibitor p21Tumor Suppressor Protein p53TelomereCell ProliferationCell Cycle CheckpointsAging, PrematureFibroblastsbeta-GalactosidaseRetinoblastoma ProteinG1 PhaseCell DivisionTelomeraseCyclinsDNA DamageCells, CulturedCell Line, TumorAgingApoptosisTelomere ShorteningGene Expression RegulationSignal TransductionMitosisCell LineS PhaseDNA-Binding ProteinsTranscription FactorsGene Expression ProfilingG2 PhaseRNA, MessengerDown-RegulationNuclear ProteinsMolecular Sequence DataTranscription, GeneticE2F Transcription FactorsPromoter Regions, GeneticGene Expression Regulation, NeoplasticOxidative StressPhenotypeCyclin AHistonesRNA, Small InterferingCDC2 Protein KinaseTumor Suppressor ProteinsProtein-Serine-Threonine KinasesTime FactorsRNA InterferenceModels, BiologicalCyclin-Dependent Kinase Inhibitor p27Base SequenceCyclin D1PhosphorylationUp-RegulationMutationCyclin B2Reactive Oxygen SpeciesCell DifferentiationCyclin Ecdc25 PhosphatasesBlotting, WesternRepressor ProteinsDNA ReplicationReverse Transcriptase Polymerase Chain ReactionOligonucleotide Array Sequence AnalysisBiological ProcessesFlow CytometryMenstrual CycleCell Transformation, NeoplasticG2 Phase Cell Cycle CheckpointsHeLa CellsTransfectionE2F1 Transcription FactorGene ExpressionAmino Acid SequenceCyclin-Dependent KinasesSaccharomyces cerevisiaeMice, Inbred C57BLDNAProtein BindingTumor Cells, CulturedTumor Suppressor Protein p14ARFGene Expression Regulation, PlantTOR Serine-Threonine KinasesPlant LeavesCyclin-Dependent Kinase 4Endothelial CellsCitric Acid CycleNeoplasmsCell NucleusMice, KnockoutG0 PhaseCyclin-Dependent Kinase 2G1 Phase Cell Cycle CheckpointsArabidopsisE2F4 Transcription FactorChromatin Immunoprecipitation