Regulation embryonic clone cells. Medical search. Frequent questions

In 1-cell and 2-cell embryos Dnmt1s is derived from the oocyte, whereas from the 2-cell stage onward the embryo starts to synthesize its own Dnmt1s 8 . (nature.com)
Furthermore, due to ethical and legal concerns, very limited techniques can be applied to human embryos to validate some of significant conclusions drawn from descriptive studies regarding human embryonic development. (nature.com)
Because ES cells are cultured from the embryoblast 4-5 days after fertilization, harvesting them is most often done from donated embryos from in vitro fertilization (IVF) clinics. (wikipedia.org)
Belgium bans reproductive cloning but allows therapeutic cloning of embryos. (wikipedia.org)
France prohibits reproductive cloning and embryo creation for research purposes, but enacted laws (with a sunset provision expiring in 2009) to allow scientists to conduct stem cell research on imported a large amount of embryos from in vitro fertilization treatments. (wikipedia.org)
Italy has a 2004 law that forbids all sperm or egg donations and the freezing of embryos, but allows, in effect, using existing stem cell lines that have been imported. (wikipedia.org)
In 2003, Spain's laws state that embryos left over from IVF and donated by the couple that created them can be used in research, including ES cell research, if they have been frozen for more than five years. (wikipedia.org)
In addition, Chinese scientists claim to have been cloning human embryos (using rabbit eggs and human DNA) since 1999 - two years before U.S. researchers accomplished this ghastly feat using only human materials - reportedly for the purposes of isolating stem cells and possibly harvesting spare organs and tissues. (thenewatlantis.com)
Embryonic stem cells can be derived legally from surplus embryos donated following IVF treatment. (eurostemcell.org)
Kaji has hailed this discovery as a "step towards the practical use of reprogramed cells in medicine, perhaps even eliminating the need for human embryos as a source of stem cells. (theinterim.com)
The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)
Most human embryos reproduced by most human cloning techniques would actually be genetically unique -- i.e., having never existed before. (lifeissues.net)
True cloning performed by nuclear transfer from an adult and differentiated somatic cell to a previously enucleated egg (somatic cell nuclear transfer, SCNT), gives rise to a new cell, the nuclovulo (nucleus+ovum), distinct from the zygote because the sperm is not involved in its creation, while both can develop as embryos and give rise to offspring. (sibi.org)
The efﬁciency of cloning, deﬁned as the proportion of transferred embryos that result in viable offspring, is approximately 2 to 3% for all species. (sibi.org)
Embryonic stem cells come from human embryos that are three to five days old. (healthline.com)
Embryonic stem cells (ESCs): These stem cells are derived from embryos and have the ability to develop into any type of cell in the body. (stemcellassurance.com)
A researcher works with stem cells from mice embryos in a stem cell lab in the Biomedical Science Building on Oct. 3, 2008. (michigandaily.com)
The initiative would overturn a 1978 Michigan law banning the destruction of embryos in research, allowing scientists to use embryos that would otherwise be discarded from fertility clinics to derive their own stem cell lines. (michigandaily.com)
Chinese scientists at various research institutions have reported successful experiments in human cloning, including the production of human-rabbit hybrid embryonic stem cells, according to the claims of Professor Lu Guangxiu at Xiangya Medical College, who told the Wall Street Journal in March of 2002 that researchers at the College had been successfully cloning embryos for two years. (publicintegrity.org)
Japan subsequently enacted legislation in late 2000 criminalizing the cloning of human embryos for reproductive purposes. (publicintegrity.org)
China enacted regulations early this year to allow the cloning of human embryos for research, and South Korea enacted similar legislation to allow research days ahead of the February announcement. (publicintegrity.org)
Human cloning involves creating embryos with the intent of implanting them in women to produce children. (boloji.com)
The bill also applies Federal ethical regulations on human subject research and outlaws the transfer of cloned embryos to a woman's uterus or to any artificial womb. (boloji.com)
At the same time, the statement calls for a five-year moratorium on the use of cloning to create human embryos for research purposes. (boloji.com)
While supporting research that would help to determine whether stem cells have therapeutic effects, they point out that those adult stem cells, umbilical cord stem cells, and embryonic stem cells not derived from embryos created for research can be used. (boloji.com)
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
We characterize the activation kinetics of these reagents in vitro and demonstrate their efficacy in zebrafish embryos that express NfsB either ubiquitously or in defined cell populations. (cdc.gov)

Sweden forbids reproductive cloning, but allows therapeutic cloning and authorized a stem cell bank. (wikipedia.org)
Yesterday, scientists in the United Kingdom announced that they'd been granted permission by the Human Fertilization and Embryology Authority to create stem cells by therapeutic cloning. (sentientdevelopments.com)
Canada should follow its lead and permit therapeutic cloning under strict regulation. (sentientdevelopments.com)
In therapeutic cloning, scientists take a human egg from a healthy donor, and remove its nucleus. (sentientdevelopments.com)
Therapeutic cloning possesses enormous potential for revolutionizing medical and thera- peutic techniques. (who.int)
This is therapeutic cloning. (who.int)
This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)
Note that each and every individual "loophole" discussed below that permits human cloning by default (and most bills have literally dozens of such loopholes) thus permits it for both "therapeutic" and for "reproductive" human cloning. (lifeissues.net)
Primary satellite cells can be harvested from muscle tissue to investigate or even use as potential therapeutic application. (sun.ac.za)
In conclusion, using clones that were distinctly different as assessed by the comparative index, this thesis illuminates that the two FGF family members investigated, act on cell cycle in different ways, thus would influence their utilization in experimental or therapeutic applications. (sun.ac.za)
The isolation and characterization of embryonic stem cells in the late 1990s opened up new possibilities for studying and utilizing these cells for therapeutic purposes. (stemcellassurance.com)
Researchers continue to work towards overcoming challenges and limitations to harness the power of stem cells for therapeutic purposes. (stemcellassurance.com)
A growing number of U.S. legislators seem prepared to support research on therapeutic cloning. (publicintegrity.org)
Before delving into the molecular biology and therapeutic potentials of induced pluripotent stem cells, it is crucial to provide foundational definitions and descriptions. (papersowl.com)
In therapeutic cloning on the other hand, genetic material from a body cell is inserted into an egg cell, replacing the nucleus. (boloji.com)
However, the Senate bill does allow for therapeutic cloning, known as 'nuclear transplantation', for research on therapies that could cure several serious and life-threatening diseases. (boloji.com)
The Society for Women's Health Research, a non-profit group, agrees that therapeutic cloning should be allowed. (boloji.com)
The potential of therapeutic cloning for treating, and perhaps curing, a variety of debilitating diseases demands that the scientific community be allowed to continue this promising work. (boloji.com)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)

When investigating the causes of this failure via cellular and molecular analysis of 2-cell zygotes and the successive cell divisions (blastomeres), all kinds of abnormalities were found. (sibi.org)
NOVOcan: a molecular link among selected glial cells. (ox.ac.uk)
Collins, a cellular and molecular biology major from Livonia, works in the neurology lab on campus, using embryonic stem cells for her research on epilepsy in rats. (michigandaily.com)
Molecular mechanisms for regulation of gene expression at different levels: remodeling of chromatin, initiation of transcription, nuclear transport and signalling, and RNA interference. (lu.se)
Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
and (i i) to develop (epi)genomic powerful molecular and/or cell biology and close col aboration to create synergies methodologies, profiling strategies, and functional genomics tools, recent progress and better exploit and further expand bioinformatics tools and resources that in understanding of the cancer (epi) unique research tools and expertise. (who.int)

Canadian regulations on embryonic stem cell research are woefully inadequate, but at least it is a criminal offence in this country to create a human embryo for medical research and to clone a human embryo for any purpose. (theinterim.com)
Thus to use the phrase "of an existing or previously existing human being" to refer to the product of human cloning would not be a scientifically accurate description of the cloned or genetically engineered human embryo -- thus creating yet another loophole in the bill or treaty. (lifeissues.net)
Among the factors thought to contribute to the greater success in cloning cattle are the relatively late embryonic genome activation speciﬁc for this species [16 -18] and the optimization of reproductive technologies, such as in vitro embryo production and embryo transfer, brought about by the cattle industry [19]. (sibi.org)
During the process of harvesting embryotic stem cells, the embryo is destroyed. (healthline.com)
Boiani M, Schöler HR. Regulatory networks in embryo-derived pluripotent stem cells. (bdbiosciences.com)
Conception" (fertilization) is the union of an oocyte and sperm cell (specifically, the fusion of the membranes of an oocyte and spermatozoon upon contact) giving rise to a new and distinct living human organism, the embryo. (sanjosearticles.com)
For example, in rare instances at an early point in embryonic development, some cells become disaggregated from the embryo and through a process of internal restitution and regulation, resolve themselves into a separate new living human organism-a monozygotic (identical) twin of the original embryo. (sanjosearticles.com)
During the first week, the embryo becomes a solid mass of cells and then acquires a cavity, at which time it is known as a blastocyst. (sanjosearticles.com)
Unfortunately, certain scientists and scientific organizations have followed such a course in the past, by arguing, for example, that the term "embryo" should not be used to describe the individual human being who is used and destroyed in embryonic stem cell (and other forms of embryo) research. (sanjosearticles.com)
In a recent landmark judgment, the European Court of Justice rightly rejected such terminological manipulation, holding that "any human ovum after fertilization, any non-fertilized human ovum into which the cell nucleus from a mature human cell has been transplanted, and any non-fertilized human ovum whose division and further development have been stimulated by parthenogenesis constitute a 'human embryo'" [ECJ 18.10.2011, C-34/10, Brustle v Greenpeace]. (sanjosearticles.com)
for the purposes of embryo research": * bring about the creation of an embryo * replace the nucleus of a cell of an embryo with a nucleus taken from any other cell * clone any embryo. (biopolicywiki.org)
Several western scientists have been conducting their research in Asian countries in the past few years, including Cibelli, formerly of Advanced Cell Technology, an early U.S. pioneer of embryo research, as well as Alan Colman, now located in Singapore, one of the scientists who helped create the first mammalian clone, the sheep Dolly. (publicintegrity.org)
When I saw the embryo, I suddenly realized there was such a small difference between it and my daughters," said Dr. Yamanaka, 45, a father of two and now a professor at the Institute for Integrated Cell-Material Sciences at Kyoto University. (cbc-network.org)
A pluripotent stem cell has the potential to form all cells of the embryo, but cannot form a placenta. (papersowl.com)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)

So far the reprogramming of somatic cells shows very low rates of efficiency (~0.0006-1%) that have not improved in the last two decades of continuous research. (sibi.org)
Induced pluripotent stem cells (iPSCs): These stem cells are created by reprogramming adult somatic cells, such as skin cells, back into a pluripotent state. (stemcellassurance.com)
In contrast, adult stem cells can only give rise to differentiated somatic cells of the particular tissue from which these cells originated (Can/Hematol 2008). (papersowl.com)
The methodology included inducing differentiated somatic cells with the primary genes responsible for embryonic stem cell potency. (papersowl.com)
In somatic cells, the activity of telomerase, a reverse transcriptase that can elongate telomeric repeats, is usually diminished after birth so that the telomere length is gradually shortened with cell divisions, and triggers cellular senescence. (nature.com)
Thus, even in stem cells, except for embryonal stem cells and cancer stem cells, telomere shortening occurs during replicative ageing, possibly at a slower rate than that in normal somatic cells. (nature.com)
Telomeric DNA consists of short guanine-rich repeat sequences in all eukaryotes with linear chromosomes, and its length in human somatic cells is remarkably heterogeneous among individuals ranging from 5 to 20 kb, according to age, organ, and the proliferative history of each cell ( Wright and Shay, 2005 ). (nature.com)
In most human somatic cells except for stem cells and lymphocytes, telomerase activity is diminished after birth so that telomere length shortens with each cell division. (nature.com)
In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)

The reproductive cloning of people is prohibited, including that for the purposes of donating organs, tissues and cells. (eurostemcell.org)
The Law on Transplantation of Organs, Tissues, and Cells (promulgated SG No. 83/19 September 2003, into force 1 January 2004) regulates the use, collection and storage (including biobanks) of all cells, organs and human tissue in Bulgaria. (eurostemcell.org)
Law on the Transplantation of Organs, Tissues and Cells (Promulgated in the State Gazette, issue No. 83/19 September 2003, entered into force on 1 January 2004), at http://bgtransplant.bg/iat/docs/Law%20on%20transplantation.doc (Word download), accessed 10 October 2011. (eurostemcell.org)
Notch-1, Jagged-1, Jagged-2, and stem cell marker Nanog are expressed in SHED cultured in KGM which may be involved in the differentiation into epithelial-like cells in human dental pulp tissues. (bvsalud.org)
Stem cells from human exfoliated deciduous teeth (SHED) are multipotent stem cells derived from the pulp tissues of extracted deciduous teeth 1 . (bvsalud.org)
Notch signaling pathway is also involved in the regulation of epithelial cell differentiation in various tissues 5-6 . (bvsalud.org)
These stem cells come from developed organs and tissues in the body. (healthline.com)
Adult stem cells: These stem cells are found in various tissues and organs of the body, such as bone marrow, blood, and adipose tissue. (stemcellassurance.com)
Plasticity: Some types of stem cells have the ability to differentiate into cell types from other tissues or organs, a property known as plasticity. (stemcellassurance.com)
The history of stem cell research dates back to the 19th century, when scientists first observed that certain cells have the ability to regenerate and repair tissues. (stemcellassurance.com)
Stem cells serve as a valuable tool for studying the development and function of various organs and tissues, as well as for modeling diseases and developing new drugs. (stemcellassurance.com)
Totipotent stem cells contain all the constituents necessary to produce a living being, given that these cells can supply all embryonic and extraembryonic tissues required for proper growth (Can/Hematol 2008). (papersowl.com)
Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. (mpi-cbg.de)
27 Jun, 2007 06:08 pm Stem cells have the potential to become all the cells and tissues in the human body. (scitizen.com)
In combination with transgenic organisms, such enzyme-actuated antisense tools will enable gene silencing in specific cell types, including tissues that are not amenable to optical targeting. (cdc.gov)

Is the Subject Area "Cell differentiation" applicable to this article? (plos.org)
Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM). (bvsalud.org)
Since the Notch signaling pathway molecules play an important role in differentiation of epithelial cells, it is important to identify the presence of notch signaling molecules in SHED during the process of cell differentiation. (bvsalud.org)
The Notch signaling pathway provides important intercellular signaling mechanisms essential for cell fate specification and it regulates differentiation and proliferation of stem or progenitor cells by para-inducing effects 3-4 . (bvsalud.org)
Differentiation: Stem cells can differentiate into specialized cell types, such as muscle cells, nerve cells, or blood cells, based on the signals they receive from their surrounding environment. (stemcellassurance.com)
A stem cell commences as an undifferentiated cell that can either undergo self-renewal, whereby it generates daughter cells that remain as stem cells, or mature into a specific cell type via differentiation (Can/Hematol 2008). (papersowl.com)
A cascade effect occurs when ras -GTPase is "switched on" by incoming signals, leading to activation of other proteins, which, in turn, activate genes responsible for cell growth and differentiation. (medscape.com)
Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)

Monkeys have served as one of the most valuable models for understanding DNA methylation dynamics during early embryogenesis in human due to their similarities in genetics and early embryonic development 17 , 18 . (nature.com)
Zygotic mutants develop to pupal stages, but do not eclose, whereas maternal mutants display severe defects in early embryonic patterning (Veraksa, 2002). (sdbonline.org)

Ironically, just eight days before Obama expanded funding for embryonic stem cell research, two teams of scientists, one led by Dr. Keisuke Kaji of the University of Edinburgh and the other by Dr. Andras Nagy of Toronto's Mount Sinai Hospital, disclosed in Nature , a leading scientific journal, that they have come up with a practical method for transforming ordinary skin cells into pluripotent stem cells. (theinterim.com)
Scientists should focus instead on legitimate avenues of research, such as the new method for creating pluripotent stem cells from skin cells. (theinterim.com)
Having played a key role in encouraging scientists to explore alternatives to embryonic stem cell research, we should not relent in our opposition to the death-dealing procedure until it is banned and stopped altogether. (theinterim.com)
Do U.S. Scientists Have a Right to Perform Human Cloning? (lifenews.com)
To prohibit any future 'political interference' with science, some scientists and biotech advocates want to permanently unmoor scientific inquiry from most societal regulation and control. (lifenews.com)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)
Note: The unfolding and often ugly details of the current contentious issues of human cloning, human embryonic stem cell research, and patient "therapies" have called into serious question the very integrity of scientists and medical researchers, of their data, of the institutions (both private and public) which fund them, of the politicians and legislators who promote them, and of the scientific and medical research enterprises themselves. (lifeissues.net)
Since stem cells have the ability to turn into various other types of cells, scientists believe that they can be useful for treating and understanding diseases. (healthline.com)
Scientists have recently discovered how to turn adult stem cells into pluripotent stem cells. (healthline.com)
To create iPSCs, scientists genetically reprogram the adult stem cells so they behave like embryonic stem cells. (healthline.com)
Scientists are hoping that the cells can be made from someone's own skin to treat a disease. (healthline.com)
In Japan, scientists at Kyoto University announced in January that they had successfully produced embryonic stem cells domestically for the first time. (publicintegrity.org)
Pro embryonic stem cell research scientists sure can get touchy about ethics. (cbc-network.org)
The implication from their attempting to force other people to take on their definitions of "ethical" stem cell research is that scientists and members of the public who support ESC research are bad people, immoral people. (cbc-network.org)
In the early 1980s, scientists began to exploit two major classes of stem cells: embryonic and non-embryonic, or adult stem cells. (papersowl.com)
As the cell begins to divide, scientists believe stem cells can be extracted and grown into tissue or organs. (boloji.com)
Scientists believe that stem cells could be used as a "repair kit" super for the body to generate healthy tissue to replace damaged by trauma or compromised by the disease. (batarakresnarental.com)
Among the conditions which scientists believe can be treated with stem cell therapy are Parkinson's disease, heart disease, stroke, arthritis, diabetes, burns and spinal cord damage. (batarakresnarental.com)
Scientists have found a way to possibly avoid using embryonic stem. (scitizen.com)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)

A common example of a stem cell is the hematopoietic stem cell (HSC) which are multipotent stem cells that give rise to cells of the blood lineage. (wikipedia.org)
In contrast to multipotent stem cells, embryonic stem cells are pluripotent and are thought to be able to give rise to all cells of the body. (wikipedia.org)
Unlike embryonic stem cells, adult stem cells are multipotent, meaning they can differentiate into a limited number of cell types. (stemcellassurance.com)
To delve further into the specifics, embryonic and adult stem cells fall into potency categories reflecting their ability to differentiate: totipotent, pluripotent, multipotent, and unipotent. (papersowl.com)
Multipotent stem cells are capable of forming many, but not all, cell types of the body. (papersowl.com)
Until recently, it was believed that they were tissue-specific…however, this concept has been challenged… (multipotent cells) can differentiate in vitro and in vivo into various cell types not only from the tissue of origin" (Can/Hematol 2008). (papersowl.com)
Using these definitions, embryonic stem cells can be classified as totipotent or pluripotent at different developmental stages and locations, whereas adult stem cells can be categorized as pluripotent, multipotent, or unipotent (Figure 1). (papersowl.com)
1983) and the multipotent progenitor cells from fetal disease (Bjorklund and Lindvall, 2000). (lu.se)

Their 'Human Cloning Prohibition Act of 2002' would prohibit human reproductive cloning by imposing significant criminal and civil penalties in the form of fines (at least $1 million) and up to ten years in prison. (boloji.com)
In June 2002, numerous international organizations joined the Collective in issuing a statement on human cloning in which they called on Congress to pass a strong, effective ban on using human cloning to create a human being. (boloji.com)
2002). In humans, SSEA4 is expressed by building the nervous system but also for their prospec- nonneural cells such as the erythrocytes (Kannagi et al. (lu.se)
explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)

While embryonic stem cells are taken from embryoblasts, induced pluripotent stem cells are undifferentiated from somatic adult cells. (wikipedia.org)
Stem cell treatments are a type of cell therapy that introduce new cells into adult bodies for possible treatment of cancer, somatic cell nuclear transfer, diabetes, and other medical conditions. (wikipedia.org)
Adult stem cells have a misleading name, because they are also found in infants and children. (healthline.com)
For example, hematopoietic stem cells are a type of adult stem cell found in bone marrow. (healthline.com)
Adult stem cells can't differentiate into as many other types of cells as embryonic stem cells can. (healthline.com)
Adult stem cells don't present any ethical problems. (healthline.com)
ENGLISH ABSTRACT: Introduction: Adult mammalian tissue regeneration recruits progenitor stem cells. (sun.ac.za)
Fibroblast Growth Factors (FGFs) are fundamental in embryonic development but also in adult skeletal muscle regeneration from injury or pathology. (sun.ac.za)
Pexidartinib is a colony-stimulating factor-1 receptor inhibitor approved in the United States for treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not amenable to improvement with surgery. (bvsalud.org)
Pexidartinib is approved for treatment of adult symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not amenable to improvement with surgery. (bvsalud.org)
These results demonstrate the loss of AND-34 dysregulates focal adhesion complex signaling in lens epithelial cells and suggest that AND-34-mediated signaling is required for maintenance of the structural integrity of the adult ocular lens. (molvis.org)
That is to say, one type of stem cell may be capable of differentiating into all adult cell types, while another may only be capable of maturing into one specific somatic cell type. (papersowl.com)
On a macro scale, the two classifications of stem cells are embryonic and adult stem cells. (papersowl.com)
However, the crowning achievement arose in 2006 when researchers at Kyoto University discovered the necessary means to reprogram differentiated adult cells to possess embryonic stem cell-like functionality, as if reversing time itself. (papersowl.com)
Adult Stem Cells: The New Plastic Surgery? (scitizen.com)
27 Jun, 2008 05:23 pm A new article in Live Science predicts that adult stem cells may replace silicone breast implants and other contemporary plastic surgery techniques. (scitizen.com)
In fact, low levels of telomerase activity have been found in human adult stem cells including haematopoietic and non-haematopoietic stem cells such as neuronal, skin, intestinal crypt, mammary epithelial, pancreas, adrenal cortex, kidney, and mesenchymal stem cells (MSCs) ( Table 1 ). (nature.com)
The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)

However, robust and large-scale genome-wide reprogramming of DNA methylome occurs during two critical developmental processes: (1) development of primordial germ cells and (2) pre-implantation embryogenesis. (nature.com)
This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)
Reproductive cloning versus germ cell (egg, ovum). (who.int)
Human embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and they are key components of germ cell tumors (GCTs). (sigmaaldrich.com)
This antibody reacts with TRA-1-60 antigen that is expressed upon the surface of human tetracarcinoma stem cells (EC), human embryonic germ cells (EG) and human embryonic stem cells (ES). (sigmaaldrich.com)
This pluripotency enables these cells to produce daughter cells of all differentiated somatic cell types, germ cells, and cells of all three embryonic germ layers (Can/Hematol 2008). (papersowl.com)
Overexpression of DEAF-1 by using a maternal driver inhibits germ-band retraction and causes defects in dorsal closure, whereas overexpression at later stages causes cell death (Reed, 2008). (sdbonline.org)
Thus, telomerase activity and telomere maintenance are associated with the immortality of cancer cells, germ-line cells, and embryonic stem (ES) cells. (nature.com)

Stem cell laws are the law rules, and policy governance concerning the sources, research, and uses in treatment of stem cells in humans. (wikipedia.org)
The European Union has yet to issue consistent regulations with respect to stem cell research in member states. (wikipedia.org)
Whereas Germany, Austria, Italy, Finland, Portugal and the Netherlands prohibit or severely restrict the use of embryonic stem cells, Greece, Sweden, Spain and the United Kingdom have created the legal basis to support this research. (wikipedia.org)
Germany has restrictive policies for stem cell research, but a 2008 law authorizes "the use of imported stem cell lines produced before May 1, 2007. (wikipedia.org)
According to modern stem cell researchers, Spain is one of the leaders in stem cell research and currently has one of the most progressive legislations worldwide with respect to human embryonic stem cell (hESC) research. (wikipedia.org)
The United Kingdom is one of the leaders in stem cell research, in the opinion of Lord Sainsbury, Science and Innovation Minister for the UK. (wikipedia.org)
A new £10 million stem cell research centre has been announced at the University of Cambridge. (wikipedia.org)
Now the U.K. is positioned to lead the world in translating the potential benefits of stem-cell research into patients. (sentientdevelopments.com)
Human embryonic stem cell research and the derivation of human embryonic stem cell lines is not directly regulated by Bulgarian legislation, but falls partially within the scope of the Bulgarian Health Act (promulgated SG No. 70/10 August 2004, into force from 1 January 2005). (eurostemcell.org)
President Barack Obama has once again demonstrated his shocking disregard for the sanctity of human life by lifting the ban on federal funding for embryonic stem cell research that was imposed by his predecessor George W. Bush. (theinterim.com)
The Bush administration at least limited federal funding for embryonic stem cell research to already-existing stem cell lines. (theinterim.com)
Now, Obama has extended federal support to research on all new, as well as old, stem cell lines produced in privately financed laboratories. (theinterim.com)
Obama has even gone so far as to suggest that the Congress should authorize human cloning for medical research. (theinterim.com)
Why, though, can Obama not grasp that human cloning for medical research is also dangerous and profoundly wrong, if only because it is all too likely to lead to human cloning for reproduction? (theinterim.com)
Similar claims have been made for embryonic stem cell research. (theinterim.com)
Obama has recalled how Christopher Reeve, the actor, quadriplegic and champion of embryonic stem cell research, once told a reporter: "If you came back here in 10 years, I expect that I'd walk to the door to greet you. (theinterim.com)
DOES THE FIRST AMENDMENT guarantee the right to conduct research into human cloning? (lifenews.com)
The Science and Bioethics Establishments are outraged by legislative attempts at the federal and state levels to outlaw human cloning and frustrated by the funding restrictions President Bush placed on embryonic stem cell research. (lifenews.com)
Having the courts issue a cloning Roe v. Wade establishing a 'right to research' would be just the ticket. (lifenews.com)
Funding of research using non-embryonic stem cells. (iowacatholicconference.org)
Public funding of abortion or embryonic stem cell research. (iowacatholicconference.org)
The "pros" and "cons" of human cloning research have already been dealt with at length in the literature, so they will not be reviewed here. (lifeissues.net)
Rather, after having published analyses of dozens of state, national, federal and international legislative attempts to ban human cloning research, I simply wish to offer seriously considered suggestions for the use of scientifically accurate language and definitions to be used in such endeavors in order to prevent loopholes which would result in much human cloning not being really banned. (lifeissues.net)
Many of these accurate definitions can also be used in bills and treaties concerning related issues, e.g., human embryonic stem cell research, human genetic engineering, abortion, the use of abortifacients, conscience clauses, IVF and other artificial reproductive technology research and regulation, etc. (lifeissues.net)
In a meeting in Washington (3 December 2001) the researcher Tanja Dominko presented the results of monkey cloning (Macacus rhesus) when she worked at the Regional Center of Research in Primates of Beaverton, Oregon (USA). (sibi.org)
But there's so much just scientifically that's happening now whether it's embryonic stem cell research, even in vitro fertilization, cloning. (wgbh.org)
However, more research is needed to help understand the potential uses of amniotic fluid stem cells. (healthline.com)
These political moralities are then used to examine current law and public policy in areas of bioethical concern, such as abortion, pre-birth testing, embryonic stem cell research, reproductive cloning, surrogate motherhood, voluntary euthanasia, and the treatment of newborn infants with severe disabilities. (monash.edu)
The unit also considers law and public policy in relation to informed consent, conflict of interest, and the regulation of research on humans. (monash.edu)
Research cloning is specifically allowed. (biopolicywiki.org)
History=The Human Reproductive Technology Ordinance of 200 appears to have prohibited research cloning, stating that "No person shall. (biopolicywiki.org)
Stem cell research has been a topic of great interest and excitement in the scientific community for many years. (stemcellassurance.com)
This field of research focuses on studying the properties and potential applications of stem cells, with the aim of advancing our understanding of the human body and developing new treatments for various diseases and conditions. (stemcellassurance.com)
In the 1960s, the discovery of bone marrow transplantation paved the way for further research into the potential medical applications of stem cells. (stemcellassurance.com)
Stem cell research is of paramount importance because it has the potential to revolutionize medicine by offering new approaches for treating diseases and conditions that were previously considered incurable. (stemcellassurance.com)
Currently, stem cell research is a rapidly evolving field, with ongoing research and clinical trials exploring the potential applications of stem cells in various fields, such as regenerative medicine, genetic disorders, organ transplants, cosmetic and plastic surgery, and drug development. (stemcellassurance.com)
She said she hopes to go on to graduate school at the University so she can research human embryonic stem cells. (michigandaily.com)
We can do animal stem cell research, but there's no way we can move forward to use it on humans - you can't put animal stem cells in people. (michigandaily.com)
There's a separate section of the proposal that say all state and local laws apply unless they constrict stem cell research," said MiCause spokesman David Doyle. (michigandaily.com)
The legislature will never be able to pass a law that deals with embryonic stem cell research. (michigandaily.com)
Sean Morrison, director of the University's Center for Stem Cell Biology, said the passage of the proposal is key if the University wants to remain a competitive research institution. (michigandaily.com)
Michigan's laws haven't prevented researchers at the University from doing embryonic stem cell research. (michigandaily.com)
LSA senior Landon Krantz, president of Student Society for Stem Cell Research, said his group has been handing out flyers in the Diag and bringing in speakers to help garner support for the ballot initiative and stem cell research. (michigandaily.com)
The privately-funded experiment, which took place at Seoul National University under the guidance of Korean Hwang Woo-suk and American Jose Cibelli, was only the latest in a group of announcements from research institutions in Asia in the last few years, and demonstrates that cloning research is becoming "globalized" like any other commodity. (publicintegrity.org)
China has reportedly been increasing its funding for cloning and other biotechnology research efforts. (publicintegrity.org)
Although stem cell research efforts have been in place for several years, the top countries in Asia have only recently begun to regulate the science. (publicintegrity.org)
The United States currently has no comprehensive law, and legislation that would have banned both research and reproductive cloning has failed to reach a vote in the Senate after approval in the House of Representatives in July 2001. (publicintegrity.org)
Knoepfler criticizes my opinion - always fair game - expressed in a blog entry today about another advance in induced pluripotent stem cell research . (cbc-network.org)
What does it mean to do ethical science in general and in particular what is ethical stem cell research? (cbc-network.org)
According to the opponents of embryonic stem cell (ESC) research, that line of research is unethical and even immoral and it is they who get to make those decisions for the rest of us. (cbc-network.org)
It is no different with embryonic stem cell research. (cbc-network.org)
Nor people on the left who have qualms about human cloning research, such as the people at the Center for Genetics and Society. (cbc-network.org)
The piece begins "Ethical stem cell research continues to advance. (cbc-network.org)
American feminists and women's health activists are debating on the difficult issue of human cloning and stem cell research. (boloji.com)
The South Korean president has pledged $ 89 million (£ 56 million) in state funds to revive the country's reputation as a world leader in stem cell research. (batarakresnarental.com)
The announcement comes five years after a damaging scandal when it was discovered a pioneer in cloning research was fake. (batarakresnarental.com)
The president said that South Korea alongside the U.S. has been a world leader in stem cell research a decade ago. (batarakresnarental.com)
Unfortunately, there was an incident that damaged inevitable disappointment to the community all stem cell research in Korea," he said, referring to the conviction of Hwang Woo-suk. (batarakresnarental.com)
As the program faltered stem cell Seoul, streamlined regulations, and other nations aggressively expanded funding for research, Mr. Lee. (batarakresnarental.com)
Father Frank Pavone, a key proponent of the Roman Catholic Church's pro-life movement, has devoted his life's work to ending abortion, euthanasia, embryonic stem cell research, and other techniques and procedures that he believes threaten human life from conception to death. (asu.edu)
8 Feb, 2008 06:09 pm Six years ago, biomedical engineer Michael King was exploring the strange rolling motion of white blood cells when his research took a radical turn. (scitizen.com)
27 Nov, 2007 10:41 am Tony Maciulis talks with Dr. Jon LaPook about a breakthrough in stem cell research. (scitizen.com)
21 Nov, 2007 10:54 am A huge advancement in stem cell research--and a stake in the heart of human cloning--was announced yesterday. (scitizen.com)
6 Sep, 2007 12:57 pm British authorities decided yesterday to permit research that uses animal eggs to create human stem cells because of the limited supply of human eggs. (scitizen.com)
25 Jun, 2007 04:43 pm On June 7, the House of Representatives voted 247-176 to pass a bill (S 5) that would allow federal funding for research using stem cells derived from. (scitizen.com)
5. Most countries in the African Region have no specific regulations and policies governing genetic manipulations for assisted conception, treatment and research. (who.int)
Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
Below you can see some examples of the infrastructure for research on genes and cells, available for researchers at Lund University. (lu.se)
Recently, research has increased in the area of transplanting embryonic cells across species and growing kidneys and endocrine pancreas cells in situ. (medscape.com)

Safety regulations and reporting requirements for abortion clinics. (iowacatholicconference.org)

General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)

Marking a vast leap in reproductive therapy, it became possible to isolate these human embryonic stem cells for reproductive purposes, such as in vitro fertilization. (papersowl.com)

Doctors have been performing stem cell transplants, also known as bone marrow transplants, for decades using hematopoietic stem cells in order to treat certain types of cancer. (healthline.com)
Hematopoietic stem cells, which can produce several different types of blood cells, are prime examples of multipotency. (papersowl.com)
We discuss these properties with examples both from the hematopoietic and embryonic stem cell (ESC) systems. (lu.se)

Nanog and transcriptional networks in embryonic stem cell pluripotency. (bdbiosciences.com)
In terminally differentiated cell fate is coupled to appropriate regulation of the alternative cells, transcriptional networks must be stable and irreversible, pathways. (lu.se)

They then take a cell -- a skin cell, for example -- from a patient, and remove its nucleus. (sentientdevelopments.com)
They put the nucleus of the patient's cell into the egg whose nucleus has been removed. (sentientdevelopments.com)
When the nucleus of a stem cell has been the technique of cloning. (who.int)
The basic techniques of of the implanted nucleus, when it fully cloning have been known for some time, and develops. (who.int)
I believe that the reprogramming errors are not the only cause of these low rates of cloning: the mammalian SCNT fails with a very high frequency mainly due to the damage that the technique itself inflicts in the egg and the somatic nucleus, and the very few successful cases occur only when the damage is not significant. (sibi.org)
Prior to SCNT, the somatic cell (differentiated) must be reprogramed to a similar state of a pluripotent embryonic cell (undifferentiated) before the nucleus is extracted and transferred. (sibi.org)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)

These cells have been described as embryonic stem cells (ESCs) and. (scitizen.com)

Specificity Comments: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. (thermofisher.com)
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. (genscript.com)
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. (bdbiosciences.com)
Expression of AND-34 regulates epithelial cell growth pattern, motility, and growth factor dependence. (molvis.org)

A variety of intrinsic and extrinsic molecules, including proteoglycans, regulate embryonic and postnatal brain development. (ox.ac.uk)

2000). In *Correspondence to: Perrine Barraud, Department of Veterinary Medi- contrast, several cell surface markers have been used to cine, Neurosciences, Madingley Road, Cambridge CB3 OES, United enrich for NSCs in the rodent CNS. (lu.se)

The have been applied to both the plant and ani- stem cells possess pluripotential charac- mal kingdoms without even stirring a ripple teristics, and can differentiate into various of concern in international conscience [ 2 ]. (who.int)
iPSCs have characteristics similar to embryonic stem cells and can differentiate into various cell types. (stemcellassurance.com)

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. (thermofisher.com)
Results and conclusion: The development of the CI was successful in determining the difference in proliferation rate for the different clones. (sun.ac.za)
There are also scientific techniques (including but not limited to somatic cell nuclear transfer, otherwise known as cloning) that bring into being a distinct new human individual at the embryonic stage of development. (sanjosearticles.com)
NOVOcan was expressed in cells lining the ventricles, including a variety of radial glia during early postnatal development. (ox.ac.uk)
These studies set the stage for determining the roles of NOVOcan in brain cell lineage patterns as well as in other aspects of development. (ox.ac.uk)
Overall, the presence of stem cells is essential for proper human development and function as they contribute to the growth, maintenance, and repair of numerous physiological systems (Kara et al. (papersowl.com)
8 Jun, 2007 04:13 pm Stem cells provide the starting material for the development and repair of every organ and tissue in the body and they are present in all stages of life. (scitizen.com)
Mechanisms that regulate development from single cell to multicellular organisms. (lu.se)
Principles of how dysregulation causes tumour growth and deviant embryonic development. (lu.se)

However, in cattle, average cloning efﬁciency is higher than in other species, ranging from 5 to 20% [10 -15]. (sibi.org)
Using probes modeled after species conserved domains of heparan sulfate proteoglycans, we cloned a novel gene called novocan, raised monoclonal antibodies against a segment of the predicted amino acid sequence of the expressed protein (NOVOcan) and used the antibodies to establish the cell and tissue localization of NOVOcan in postnatal rat brains by immunohistochemistry. (ox.ac.uk)
Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)

Proponents of the ballot initiative, including a group called Cure Michigan, are pushing for the proposal to pass because embryonic stem cells have the potential to cure diseases like Parkinson's disease and diabetes. (michigandaily.com)
4] Porcine skin has been grafted onto burn patients,[5] and pig neuronal cells have been transplanted into patients with Parkinson (Parkinson's) disease and Huntington (Huntington's) disease. (medscape.com)

Cord blood stem cells are harvested from the umbilical cord after childbirth. (healthline.com)

While an international framework to regulate cloning remains stalled in the United Nations, some Asian countries are offering more stable climates for researchers to pursue their work. (publicintegrity.org)

It wasn't until over a decade later, in the late 1990s, that human-derived stem cells were propelled to the forefront of experimentation. (papersowl.com)

For improving our understanding of epigenetic regulation of gene expression: the biological mechanisms that affect how genetic information is variably expressed. (wraltechwire.com)
An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. (thermofisher.com)
Knowledge on the expression analysis of Notch signaling pathway molecules in SHED cultured in KGM could highlight its involvement in controlling the biological activity of these stem cells, particularly during odontogenesis and other developmental process. (bvsalud.org)
Their failures or incompletion (regulation and gene expression, epigenetic, etc.) are attributed to the inviability and losses detected in the laboratory as well as the pathologies observed during the animal´s pregnancy and offspring after birth or later. (sibi.org)
ORF sequences can be delivered in our standard vector, pcDNA3.1 + /C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. (genscript.com)
Unlike FGF2, individual treatment with FGF6 was adequate to activate the quiescent PHMs and aid their re-entry into cell cycle with consistency in all three PHM clones by upregulating ki67 expression. (sun.ac.za)
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. (bdbiosciences.com)
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. (bdbiosciences.com)
DEAF-1 activates the expression of Mtk and Drs promoter-luciferase fusion genes in S2 cells. (sdbonline.org)
Briefly, eight RNA polymerase I plasmids (for the synthesis of the eight influenza A viral RNAs) together with plasmids for the expression of the PB2, PB1, PA, and NP proteins derived from the influenza A virus strain A/WSN/33 (H1N1) were transfected into 293T cells. (cdc.gov)
Principles for regulation of gene expression through intercellular signalling. (lu.se)
Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)

Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)

16 , 17 In particular, transgenic zebrafish lines that express nfsB in β cells, cardiomyocytes, or other cell types have been established, and their exposure to the metronidazole leads to the targeted loss of these cells. (cdc.gov)

HN - 2008 BX - Von Ebner's Glands MH - Cumulus Cells UI - D054885 MN - A05.360.319.114.630.535.200.500 MN - A06.407.312.497.535.300.500 MN - A11.436.300.500 MS - The granulosa cells of the cumulus oophorus which surround the OVUM in the GRAAFIAN FOLLICLE. (bvsalud.org)

Indeed, if the legal scholars and bioethicists Alexander interviewed are right, conducting experiments in human cloning-not to mention other equally controversial areas of scientific inquiry-will one day be as constitutionally guaranteed as is my writing of this article. (lifenews.com)

Finally, FGF6 and FGF2, both individually and sequentially, were used to treat quiescent myoblasts to determine their involvement in activation and proliferation with the use of cell cycle analysis and mRNA assessment of ki67, p21, myf5, and MyoD. (sun.ac.za)

The information presented here covers the legal implications of embryonic stem cells (ES), rather than induced pluripotent stem cells (iPSCs). (wikipedia.org)
These new types of cells are called induced pluripotent stem cells (iPSCs). (healthline.com)

In January 2007, researchers at Wake Forest University reported that "stem cells drawn from amniotic fluid donated by pregnant women hold much of the same promise as embryonic stem cells. (wikipedia.org)
18 Sep, 2007 12:13 pm Rice University researchers have engineered musculoskeletal cartilages with human embryonic stem cells, with the hope of eventually using the neotissue. (scitizen.com)
6 Jun, 2007 07:00 pm Researchers have reprogrammed skin cells into embryonic stem cells. (scitizen.com)

Embryonic stem cells were isolated in mice in 1981, and in humans in 1998. (wikipedia.org)
All humans start out as only one cell. (healthline.com)
While promising, these cells were solely murine-derived, limiting their applicability to humans. (papersowl.com)
Basically, given the difference of telomere and telomerase activity in human and mouse cells, the telomere and telomerase status in stem cell populations is different between humans and mice ( Harrington, 2004 ). (nature.com)

WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)

The key is that the DNA, the genetic material in those embryonic stem cells, comes from the patient, whose immune system won't reject the stem cells. (sentientdevelopments.com)

Bulgarian Centre for Bioethics, at http://www.bio-ethics.net/en/content/mission , accessed 7 November 2011. (eurostemcell.org)
But the fateful tenor of the President's Bioethics Council report on the "possible" regulation of the in vitro fertilization (IVF) industry is as expected, and was already apparent in recent publications and web postings by industry leaders. (lifeissues.net)

The following product was used in this experiment: SOX2 (Embryonic Stem Cell Marker) Recombinant Rabbit Monoclonal Antibody (SOX2/4267R) from Thermo Fisher Scientific, catalog # 6657-RBM7-P1. (thermofisher.com)

Undifferentiated mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis Kit. (bdbiosciences.com)
The entire BD Mouse Pluripotent Stem Cell Transcription Factor Analysis Kit must be stored in the dark at 2° to 8°C. Do not freeze. (bdbiosciences.com)

Myo10 in brain: developmental regulation, identification of a headless isoform and dynamics in neurons. (genscript.com)
Gene regulation in developmental biology and the cell cycle. (lu.se)

Twenty years have passed since Dolly the sheep was born by cloning (somatic cell nuclear transfer, SCNT) but the results of non-human mammalian cloning are very poor, and cause animal diseases and huge biological losses. (sibi.org)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)

Madin-Darby canine kidney (MDCK) cells were maintained in Eagle's minimal essential medium (MEM) containing 5% newborn calf serum (NCS). (cdc.gov)

RNA was reverse-transcribed to obtain the cDNA and then proceeded with PCR using specific primers for the Notch signaling pathway molecules (Notch1, Jagged-1, Jagged-2 and, Hes1) as well as stem cell marker (Nanog). (bvsalud.org)
The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)
Our facilities provide the opportunity to study molecules, cells, organs and entire organisms. (lu.se)

The stage-specific embryonic antigen 4 (SSEA4) is com- isolate the NSCs from neonatal mice and rats (Campos monly used as a cell surface marker to identify the pluri- et al. (lu.se)

Critical epigenetic regulation of primate embryogenesis entails DNA methylome changes. (nature.com)

However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker. (thermofisher.com)
CD133+), but are rarely codetected with the neural stem dents, very few human-specific NSC markers have been cell (NSC) marker CD15. (lu.se)

The Chinese Ministry of Health recently approved plans for the country's first state-run stem cell bank, and although the facility is smaller than stem cell banks in the U.S., it will likely become the largest such bank in Asia. (thenewatlantis.com)
We have to regain our national reputation as a power of stem cells," he said, adding that the government streamline the rules and establish a stem cell bank in the state. (batarakresnarental.com)

Anatomy10

Organisms3

Chemicals and Drugs21

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Phenomena and Processes37

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Information Science4

Health Care1

Embryos29

Therapeutic19

Molecular6

Embryo15

Somatic cells9

Tissues15

Differentiation10

Early embryonic2

Scientists21

Multipotent8

20024

Adult20

Germ8

Research70

Abortion1

Prohibit1

Reproductive purposes1

Hematopoietic3

Transcriptional networks2

Nucleus8

ESCs1

Regulates4

Intrinsic and extrinsic1

20001

Differentiate into various2

Development9

Species3

Parkinson's2

Umbilical cord1

Regulate1

Late 1990s1

Expression12

Progenitor2

Cardiomyocytes1

Ovum1

Experiments in human1

MRNA1

IPSCs2

Researchers3

Humans4

19972

Genetic material1

Bioethics2

Monoclonal1

Pluripotent stem2

Developmental2

Nuclear2

Kidney1

Molecules3

Isolate1

Epigenetic1

Marker2

Stem cell bank2