• Previously, promoter-GUS fusions showed that high expression of apyrase was associated with areas of rapid growth and regions with high auxin levels. (utexas.edu)
  • DNA microarrays revealed that decreased expression of apyrase leads to increased levels of transcripts coding for cell wall proteins involved in growth and genes involved in energy transfer and starch synthesis. (mpg.de)
  • The investigation of the subcellular localization of apyrases showed that some fraction of apyrase was localized on cell periphery. (utexas.edu)
  • To place these results in context, we determined the subcellular localization of the potato-specific apyrase. (mpg.de)
  • Through its hydrolysis of extracellular nucleotides, NTPDase-1 plays a role in the regulation of purinergic signaling (4). (rndsystems.com)
  • These findings provide a new marker of T cell exhaustion, and implicate the purinergic pathway in the regulation of T cell exhaustion. (ox.ac.uk)
  • Pollen tube elongation was inhibited by suppression of apyrase activity using anti-apyrase antibodies or by chemical inhibitors of apyrases. (utexas.edu)
  • Silencing of the apyrase gene family with RNA interference constructs under the control of the constitutive 35S promoter led to a strong decrease in apyrase activity to below 10% of the wild-type level. (mpg.de)
  • In this dissertation, I describe the important role of two Arabidopsis apyrases in the regulation of plant growth. (utexas.edu)
  • In this study, we used reverse genetic and biochemical approaches to investigate the role of potato (Solanum tuberosum)-specific apyrase. (mpg.de)
  • We describe the evidence that underlies both this fact and that potato-specific apyrase has a crucial role in regulating growth and development. (mpg.de)
  • They favor the hypothesis that Arabidopsis apyrases, like their homologs in animals, control the levels of ATP in the extracelluar space, and this control allows them to act as key regulators in growth. (utexas.edu)
  • Regulation of Respiration and Fermentation to Control the Plant Internal Oxygen Concentration. (mpg.de)
  • Because of the lethality of apy1apy2 double mutants, RNA interference (RNAi) was performed as an alternative approach to posttranscriptionally silence the expression of apyrases. (utexas.edu)
  • The suppression of apyrases in the RNAi lines resulted in a dwarf phenotype in overall vegetative growth and dramatically reduced growth in primary root and etiolated hypocotyls. (utexas.edu)
  • Microglial sensing of ATP, the ensuing microglia-dependent production of adenosine, and the adenosine-mediated suppression of neuronal responses via the adenosine receptor A1R are essential for the regulation of neuronal activity and animal behaviour. (nih.gov)
  • [ 28 ] Adenosine is generated in the extracellular space by the breakdown of ATP through a series of ectoenzymes, including apyrase and ecto-5'-nucleotidase. (medscape.com)
  • The intracellular amino and carboxyl termini play significant roles in determining the time-course and regulation of channel gating-for example, the C terminus regulates recovery from the desensitized state following agonist washout. (rupress.org)
  • This suggested a functional change in the cell following migration that may have been attributable to TRPC5, for example, channel up-regulation. (researchgate.net)
  • Circular RNAs (circRNAs) represent a milieu of non-coding RNAs that play a major role in gene regulation, development, and carcinogenesis. (atlantis-press.com)