Regulates distinct target genes. Medical search. Frequent questions

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Anatomy20

Cell Line, Tumor Cell Line Cells, Cultured Chromatin Cell Nucleus HEK293 Cells HeLa Cells Embryo, Nonmammalian Wing Tumor Cells, Cultured COS Cells NIH 3T3 Cells Hep G2 Cells HCT116 Cells Liver Embryonic Stem Cells Fibroblasts Embryo, Mammalian Hepatocytes 3T3 Cells

Organisms11

Drosophila Mice, Knockout Mice, Inbred C57BL Drosophila melanogaster Mice, Transgenic Animals, Genetically Modified Cercopithecus aethiops Arabidopsis Zebrafish Saccharomyces cerevisiae Caenorhabditis elegans

Diseases2

Cell Transformation, Neoplastic Breast Neoplasms

Chemicals and Drugs115

Transcription Factors DNA-Binding Proteins Repressor Proteins MicroRNAs Trans-Activators Homeodomain Proteins Nuclear Proteins RNA, Messenger Drosophila Proteins Basic Helix-Loop-Helix Transcription Factors beta Catenin RNA, Small Interfering Tumor Suppressor Protein p53 Wnt Proteins Proto-Oncogene Proteins c-myc Receptors, Cytoplasmic and Nuclear Receptors, Notch Luciferases Chromatin TCF Transcription Factors Hedgehog Proteins Proto-Oncogene Proteins Histones DNA Primers Hypoxia-Inducible Factor 1, alpha Subunit DNA Kruppel-Like Transcription Factors Wnt1 Protein Recombinant Fusion Proteins Polycomb-Group Proteins Histone Deacetylases Tumor Suppressor Proteins Estrogen Receptor alpha Orphan Nuclear Receptors Receptor, Notch1 Insect Proteins p300-CBP Transcription Factors Histone-Lysine N-Methyltransferase NF-kappa B Lymphoid Enhancer-Binding Factor 1 Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Co-Repressor Proteins Membrane Proteins 3' Untranslated Regions Receptors, Retinoic Acid Hypoxia-Inducible Factor 1 Intracellular Signaling Peptides and Proteins Neoplasm Proteins Cell Cycle Proteins Zebrafish Proteins E2F1 Transcription Factor Carrier Proteins Protein Isoforms Receptors, Steroid Transcription Factor 7-Like 2 Protein Histone Acetyltransferases PPAR alpha Polycomb Repressive Complex 2 Cyclin-Dependent Kinase Inhibitor p21 Oncogene Proteins, Fusion Forkhead Transcription Factors RNA, Plant Xenopus Proteins Oncogene Proteins Receptors, Thyroid Hormone Basic-Leucine Zipper Transcription Factors DNA, Complementary Armadillo Domain Proteins E2F Transcription Factors Nerve Tissue Proteins Receptors, Aryl Hydrocarbon STAT3 Transcription Factor Proteins Receptors, Androgen Protein-Serine-Threonine Kinases CREB-Binding Protein Ligands Transcription Factor RelA Smad3 Protein Cytoskeletal Proteins Transforming Growth Factor beta Immunoglobulin J Recombination Signal Sequence-Binding Protein Green Fluorescent Proteins PPAR gamma E1A-Associated p300 Protein NF-E2-Related Factor 2 Axin Protein Retinoid X Receptors Apoptosis Regulatory Proteins Proto-Oncogene Proteins c-mdm2 Smad4 Protein Tretinoin Intercellular Signaling Peptides and Proteins Smad Proteins Sterol Regulatory Element Binding Protein 1 Histone Demethylases Receptors, Glucocorticoid Arabidopsis Proteins Smad2 Protein LIM Domain Proteins Phosphoproteins Nuclear Receptor Coactivators Polycomb Repressive Complex 1 Proto-Oncogene Protein c-fli-1 Jumonji Domain-Containing Histone Demethylases Transcription Factor 7-Like 1 Protein RNA Core Binding Factor Alpha 2 Subunit Veratrum Alkaloids Saccharomyces cerevisiae Proteins Recombinant Proteins Adaptor Proteins, Signal Transducing T-Box Domain Proteins Receptors, Estrogen Lysine

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Chromatin Immunoprecipitation Gene Expression Profiling Oligonucleotide Array Sequence Analysis Reverse Transcriptase Polymerase Chain Reaction Transfection Gene Targeting Gene Knockdown Techniques Blotting, Western Models, Biological Real-Time Polymerase Chain Reaction Electrophoretic Mobility Shift Assay In Situ Hybridization Models, Genetic Polymerase Chain Reaction Immunoprecipitation Two-Hybrid System Techniques Blotting, Northern Microarray Analysis Immunoblotting Immunohistochemistry Sequence Analysis, RNA Cloning, Molecular Sequence Alignment Sequence Analysis, DNA Gene Knockout Techniques Cluster Analysis

Phenomena and Processes78

Gene Expression Regulation Promoter Regions, Genetic Transcription, Genetic Transcriptional Activation Signal Transduction Base Sequence Gene Expression Regulation, Developmental Protein Binding Gene Expression Regulation, Neoplastic Binding Sites RNA Interference Response Elements Genes, Reporter Mutation Transfection Cell Proliferation Down-Regulation Gene Regulatory Networks Gene Silencing Cell Differentiation Chromatin Gene Expression Apoptosis Up-Regulation Protein Structure, Tertiary Amino Acid Sequence Genes, Insect Phenotype Wnt Signaling Pathway Zinc Fingers Acetylation Cell Cycle Body Patterning Phosphorylation Gene Expression Regulation, Plant 3' Untranslated Regions Genes, myc Transcriptome Regulatory Elements, Transcriptional Plasmids Conserved Sequence Enhancer Elements, Genetic Methylation Gene Deletion Gene Expression Regulation, Fungal Consensus Sequence Genome Genes, Homeobox Active Transport, Cell Nucleus Cell Hypoxia Genetic Vectors Chromatin Assembly and Disassembly Epigenesis, Genetic Genes, Neoplasm Genes, p53 Time Factors Amino Acid Motifs Cell Survival Regulatory Sequences, Nucleic Acid Organ Specificity Transgenes Dimerization Nucleotide Motifs Genome, Human Feedback, Physiological DNA Methylation E-Box Elements Sequence Homology, Amino Acid Gene Expression Regulation, Bacterial Cell Division Gene Library Gene Expression Regulation, Enzymologic Helix-Loop-Helix Motifs DNA Damage Multigene Family Morphogenesis Protein Transport Genes, Tumor Suppressor

Disciplines and Occupations3

Computational Biology Immunohistochemistry Genomics

Information Science4

Molecular Sequence Data Base Sequence Amino Acid Sequence Feedback, Physiological

Health Care1

Cluster Analysis

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Transcription Factors Gene Expression Regulation Molecular Sequence Data Promoter Regions, Genetic DNA-Binding Proteins Transcription, Genetic Chromatin Immunoprecipitation Repressor Proteins Transcriptional Activation Signal Transduction MicroRNAs Gene Expression Profiling Oligonucleotide Array Sequence Analysis Cell Line, Tumor Trans-Activators Base Sequence Gene Expression Regulation, Developmental Protein Binding Homeodomain Proteins Nuclear Proteins Reverse Transcriptase Polymerase Chain Reaction Gene Expression Regulation, Neoplastic Cell Line Binding Sites RNA, Messenger Drosophila Proteins Basic Helix-Loop-Helix Transcription Factors RNA Interference Response Elements beta Catenin RNA, Small Interfering Genes, Reporter Mutation Tumor Suppressor Protein p53 Transfection Cell Proliferation Wnt Proteins Proto-Oncogene Proteins c-myc Down-Regulation Receptors, Cytoplasmic and Nuclear Gene Targeting Gene Regulatory Networks Gene Silencing Drosophila Cell Differentiation Receptors, Notch Luciferases Cells, Cultured Chromatin Gene Expression Apoptosis Gene Knockdown Techniques Mice, Knockout TCF Transcription Factors Cell Nucleus Hedgehog Proteins Up-Regulation Blotting, Western Proto-Oncogene Proteins Histones DNA Primers Hypoxia-Inducible Factor 1, alpha Subunit Protein Structure, Tertiary Models, Biological Amino Acid Sequence HEK293 Cells DNA Kruppel-Like Transcription Factors Wnt1 Protein Mice, Inbred C57BL Real-Time Polymerase Chain Reaction Electrophoretic Mobility Shift Assay Drosophila melanogaster Recombinant Fusion Proteins Genes, Insect Phenotype Polycomb-Group Proteins HeLa Cells Histone Deacetylases Wnt Signaling Pathway Mice, Transgenic Tumor Suppressor Proteins Embryo, Nonmammalian Estrogen Receptor alpha Zinc Fingers Wing Orphan Nuclear Receptors In Situ Hybridization Computational Biology Acetylation Cell Cycle Receptor, Notch1 Body Patterning Phosphorylation Insect Proteins p300-CBP Transcription Factors Histone-Lysine N-Methyltransferase Models, Genetic Animals, Genetically Modified Tumor Cells, Cultured

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