Regulates cyclic amp dependent protein kinases. Medical search. Frequent questions

The activity of tyrosine hydroxylase is regulated by phosphorylation and through the regulation of its expression. (xray.cz)
Phosphorylation at Ser-40 by cyclic AMP-dependent protein kinase (PKA) induces the most potent activation of tyrosine hydroxylase. (xray.cz)
Phosphorylation at Ser‑19 induces binding of the 14‑3‑3 protein, which affects the structure of the regulatory domain and protects it against dephosphorylation (at phosphorylated Ser-40) and its degradation [4, 5]. (xray.cz)
A group of enzymes that are dependent on CYCLIC AMP and catalyze the phosphorylation of SERINE or THREONINE residues on proteins. (rush.edu)
Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. (antikoerper-online.de)
Biochemical validation, mass spectrometry and peptide spot arrays revealed that PKA phosphorylates ATG16L1α at Ser268 and ATG16L1β at Ser269, driving phosphorylation-dependent degradation of ATG16L1 protein. (mdc-berlin.de)
Translocation and structure switch of STING provides the prerequisite for TANK-binding kinase 1 (TBK1) recruitment and auto-phosphorylation. (frontiersin.org)
Regulating protein breakdown through proteasome phosphorylation. (harvard.edu)
It is possible that M2 and M2 come from dif-ferent modification of receptor proteins, such as phosphorylation, methylation, association with other protein or polymerization. (nii.ac.jp)
Publications] Y. Watanabe: 'Effect of phosphorylation of inhibitory GTP-binding protein by cyclic AMP-dependent protein kinase on its ADP-ribosylation by pertussis toxin, islet-activating protein. (nii.ac.jp)
The method, named Predikin, identifies key conserved substrate-determining residues in the kinase catalytic domain that contact the substrate in the region of the phosphorylation site and so determine the sequence surrounding the phosphorylation site. (biomedcentral.com)
Predikin now consists of two components: (i) PredikinDB, a database of phosphorylation sites that links substrates to kinase sequences and (ii) a Perl module, which provides methods to classify protein kinases, reliably identify substrate-determining residues, generate scoring matrices and score putative phosphorylation sites in query sequences. (biomedcentral.com)
New features in Predikin include the use of SQL queries to PredikinDB to generate predictions, scoring of predictions, more reliable identification of substrate-determining residues and putative phosphorylation sites, extended options to handle protein kinase and substrate data and an improved web interface. (biomedcentral.com)
The post-translational modification of proteins by phosphorylation of serine, threonine or tyrosine residues is a ubiquitous process in cellular regulation. (biomedcentral.com)
Protein kinases, the enzymes responsible for protein phosphorylation, make up almost 2% of protein-encoding genes in the human genome [ 1 ] and an estimated 30-50% of human proteins are phosphorylated [ 2 ]. (biomedcentral.com)
We show that MAPKAP kinase-2 phosphorylates CREB at Ser133 in vitro, that the FGF- or stress-induced activation of MAPKAP kinase-2 and phosphorylation of CREB and ATF-1 are prevented by similar concentrations of the specific p38 MAP kinase inhibitor SB 203580, and that MAPKAP kinase-2 is the only detectable SB 203580-sensitive CREB kinase in SK-N-MC cell extracts. (dundee.ac.uk)
Here DARPP-32 phosphorylation by protein kinase A (PKA), DARPP-32 into a powerful protein phosphatase 1 (PP1) inhibitor. (pp1a.com)
DARPP-32 can itself inhibit the following PKA DARPP-32 phosphorylation by cyclin-dependent kinase 5 (Cdk5). (pp1a.com)
Mechanistic investigations revealed reduce GR-Ser211 phosphorylation following PP1α silencing and provide the first indication of the involvement of glycogen synthase kinase 3 (GSK-3). (pp1a.com)
To map the mechanisms of aggressiveness we aimed to investigate changes in protein phosphorylation across WHO grades of human meningiomas. (nature.com)

To investigate the role of the cAMP-dependent protein kinase (PKA) in the desensitization and down-regulation of the D 1 dopamine receptor, we stably expressed the rat cDNA for this receptor in mutant Chinese hamster ovary (CHO) cell lines deficient in PKA activity. (aspetjournals.org)
We demonstrate here that the kinases Gsk3β and cAMP-dependent protein kinase A (PKA) are novel determinants of IZ formation and cooperate with E(Spl) activity in a dose-dependent manner. (biologists.com)
The cAMP-dependent protein kinase A (PKA) regulates various cellular functions in health and disease. (mdc-berlin.de)
A kinase anchoring proteins (AKAPs) compromise the largest group of multifunctional scaffolding proteins, which anchor not only Type II cAMP- dependent protein kinase (PKA), but also a variety of protein kinases, phosphatases, phosphodiesterases and targets of second messenger regulated signaling. (grantome.com)
cAMP activates the cAMP-dependent protein kinase (PKA). (nih.gov)

In Saccharomyces cerevisiae, Snf1 protein kinase has three isoforms of the β subunit that confer versatility on the kinase and that exhibit distinct patterns of subcellular localization. (elsevierpure.com)
The D2S and D2L dopamine receptor isoforms are differentially regulated in Chinese hamster ovary cells. (aspetjournals.org)
Arrestin3 (but not arrestin2) depletion enhanced A2BR-AC signalling and attenuated A2BR desensitization, while ß2AR-AC signalling was regulated by both arrestin isoforms. (bvsalud.org)
However, the effect of FGF is not mediated by cyclic AMP-dependent protein kinase, TPA-sensitive isoforms of protein kinase-C, p70(S6K) or p90(rsk) (all of which phosphorylate CREB at Ser133 in vitro). (dundee.ac.uk)

Phosphodiesterases (PDEs) regulate the local concentration of 3',5' cyclic adenosine monophosphate (cAMP) within cells. (nih.gov)
Considerably higher resistance against cyclic nucleotide phosphodiesterases compared to dibutyryl- or 8-Br-cAMP (Cat. (biolog.de)

2020 ) Cyclic AMP-dependent protein kinase and D1 dopamine receptors regulate diacylglycerol lipase-α and synaptic 2-arachidonoyl glycerol signaling. (neurotree.org)
2018 ) Dorsal BNST α-adrenergic receptors produce HCN-dependent excitatory actions that initiate anxiogenic behaviors. (neurotree.org)
Our results suggest that PKA significantly contributes to the desensitization and down-regulation of D 1 receptors in CHO cells and that type II PKA may be the more relevant isoform with respect to regulating D 1 receptor function. (aspetjournals.org)
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms. (aspetjournals.org)
Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11. (aspetjournals.org)
Vasoconstrictors interact with their cognate G protein coupled receptors activating a variety of signalling pathways to promote smooth muscle proliferation. (bvsalud.org)
However, despite numerous studies indicating that ß2AR and A2BR can be substrates for GRK/arrestin proteins, currently little is known regarding GRK/arrestin regulation of these endogenous receptors in arterial smooth muscle. (bvsalud.org)
This study provides a first demonstration of how different complements of GRK and arrestin proteins contribute to the regulation of signalling and desensitization of these important receptors mediating vasodilator responses in arterial smooth muscle. (bvsalud.org)
Publications] A. Mizushima: 'The H-L subgroup of guinea-pig cardiac M_2 receptors (M_2 ) regulates formation of inositol phosphates. (nii.ac.jp)
Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES. (bvsalud.org)

Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis. (uchicago.edu)
cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases. (harvard.edu)
Fibroblast growth factor (FGF) activates a protein kinase cascade in SK-N-MC cells that regulates gene expression at a cyclic-AMP response element (CRE) by stimulating the transcriptional activity of CREB. (dundee.ac.uk)
We also show that transfection of RK/p38 MAP kinase in SK-N-MC cells, but not transfection of p44 MAP kinase, activates Gal4-CREB-dependent transcription via Ser133. (dundee.ac.uk)
Beta-adrenergic stimulation activates adenylate cyclase, which increases cyclic adenosine monophosphate (AMP) levels and causes increased calcium influx into myocardial cells. (medscape.com)

Dopamine and cyclic-AMP activated Mr32kDa phosphoprotein (DARPP-32) is a central signaling proteins in neurotransmission. (pp1a.com)

We demonstrate here that PDE4 inhibitors enhance the anti-inflammatory cytokine interleukin-1 receptor antagonist (IL-1Ra) secretion in LPS-activated mouse peritoneal macrophages, and this response was regulated at the transcriptional level rather than an increased IL-1Ra mRNA stability. (ox.ac.uk)

A class of protein-serine-threonine kinases that was originally found as one of the three types of kinases that phosphorylate GLYCOGEN SYNTHASE. (rush.edu)
This graph shows the total number of publications written about "Glycogen Synthase Kinases" by people in this website by year, and whether "Glycogen Synthase Kinases" was a major or minor topic of these publications. (rush.edu)
Research over the last decade has revealed that lithium's effects as mood stabilization and regeneration of new brain cells (neurogenesis), are mainly due to the inhibition of a key enzyme called GSK-3β, glycogen synthase kinase-3β. (jeffreydachmd.com)

These findings establish a novel mechanism of regulation of Snf1 protein kinase by the PKA pathway. (elsevierpure.com)
Here we outline the current status of the viral evasion mechanism underlying the regulation of the cGAS-STING pathway, focusing on how post-transcriptional modifications, viral proteins, and non-coding RNAs involve innate immunity during viral infection, attempting to inspire new targets discovery and uncover potential clinical antiviral treatments. (frontiersin.org)
An important signaling pathway involved in the regulation of neuronal function is the cyclic AMP/Protein kinase A pathway. (pasteur.fr)
Evidence is accumulating that small G proteins are involved in the regulation of cell growth and differentiation. (nii.ac.jp)

We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. (biomedcentral.com)
Crystal structures of protein kinases with bound substrate peptides show that substrate residues at positions -3 to +3 relative to the phosphorylated serine, threonine or tyrosine residue adopt an extended conformation and bind to a pocket in the catalytic domain of the protein kinase [ 8 ]. (biomedcentral.com)

The models of most immune evasion during innate immune responses are conserved, including altering the post-transcriptional modifications (PTMs) of vital proteins to inactivate or degrade these components, eluding DNA sensing from PRRs, decreasing cyclic GMP-AMP (cGAMP) cellular abundance, and modifying metabolism approach in host cells ( Eaglesham and Kranzusch, 2020 ). (frontiersin.org)

Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages. (ox.ac.uk)
PKN, casein kinase 1, phosphodiesterase 4D3, protein phosphatases 1 and 2a and calmodulin as well as a number of putative downstream effectors. (grantome.com)

Cyclic AMP-Dependent Protein Kinase Type II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)

Luciferase reporter assays demonstrated that the Adcy1 promoter is selectively activated by neuronal PAS-domain protein 2 (NPAS2)/BMAL1. (jneurosci.org)

The second factor, termed peptide specificity, describes the interaction between amino acid residues in the catalytic domain of the protein kinase and the substrate residues that surround the phosphorylated residue. (biomedcentral.com)
The relative contribution of substrate recruitment and peptide specificity to protein kinase substrate specificity varies between protein kinases. (biomedcentral.com)
However, it is recognised that for many protein kinase families, particularly those that phosphorylate Ser/Thr residues, peptide specificity is the major factor that determines substrate specificity. (biomedcentral.com)
The prediction of peptide specificity is therefore the basis for most of the available computational methods aimed at predicting substrates of protein kinases. (biomedcentral.com)
Subcellular sequestration of second messenger-dependent mechanisms provides for specificity of signaling to discrete organelle systems or, in the case of polarized epithelial cells, plasma membrane domains. (grantome.com)

It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. (antikoerper-online.de)
How a particular protein kinase recognises its substrate protein(s) is therefore a key question. (biomedcentral.com)
Two major factors determine the formation of a protein kinase-substrate complex [ 4 ]. (biomedcentral.com)
The first, termed substrate recruitment, encompasses any process that increases the effective concentration of the protein kinase substrate. (biomedcentral.com)

A cyclic AMP-dependent protein kinase subtype primarily found in particulate subcellular fractions. (uchicago.edu)
While we and others have demonstrated that AKAP350 can potentially scaffold a wide range of proteins, the actual composition of scaffolded complexes is likely both cell specific as well as subcellular organelle specific. (grantome.com)

PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy. (harvard.edu)
Cardiac maCh-R (M2 subtype) are thought to consist of a single species of receptor protein. (nii.ac.jp)
The results showed that cardiac maCh-R consist of two subclasses, both regulated by GTP binding proteins. (nii.ac.jp)
Objective: The aim was to clarify the role of cyclic AMP dependent protein kinase (PKA) and changes in mechanical heart function during development of cardiac hypertrophy induced by volume overload. (uchile.cl)

They are tetrameric proteins that contain two catalytic subunits and two type II-specific regulatory subunits. (uchicago.edu)
Rgs1, a regulator of G-protein signaling, interacts with all the three G subunits and functions as a negative regulator of G-proteins in [52]. (bio2009.org)
The function consequences of mutation in loop 3 of CRP are similar to that of site A and site B in the regulatory subunits of cyclic AMP-dependent protein kinases. (utmb.edu)

In a forward screen for genes affecting neurotransmission in Drosophila, we identified mutations in dynamin-related protein (drp1). (nih.gov)
Several regulatory proteins such as dynamin-related protein 1 (Drp1) are required to maintain mitochondrial morphology via a balance between continuous fusion and fission. (en-journal.org)

Unlike other dynamin family proteins, however, Drp1 does not have a lipid-interacting pleckstrin homology domain [ 7 ], and thus the anchorage of Drp1 to the mitochondrial membrane is mediated by its receptor binding. (en-journal.org)

The Snf1/AMP-activated protein kinase family has diverse roles in cellular responses to metabolic stress. (elsevierpure.com)
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. (musc.edu)
The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. (antikoerper-online.de)
Protein kinases and their substrates regulate essentially all cellular processes through complex regulatory networks, in which phosphorylated proteins act as switches that tune the response of the cell to environmental stimuli. (biomedcentral.com)
Instead, we identify the FGF-stimulated CREB kinase as MAP kinase-activated protein (MAPKAP) kinase-2, an enzyme that lies immediately downstream of p38 MAP kinase, in a pathway that is also stimulated by cellular stresses. (dundee.ac.uk)
In siliteo analysis reinforced previously reported anti-inflammatory actions of 5-MeO-DMT & revealed modulatory effects on proteins associated with long-term potentiation, the formation of dendritic spines, including those involved in cellular protrusion formation, microtubule dynamics, and cytoskeletal reorganization. (baoninhsunrise.com)

Alpha-adrenergic receptor stimulation produces a cascade of second messenger systems that subsequently regulate calcium channels and in turn elicit increases in cytosolic calcium. (medscape.com)

Differentially regulated pathways were characteristic of high-grade meningiomas. (nature.com)
Out of the 6,728 identified proteins, 934 were found differentially expressed in 5-MeO-DMT-treated cerebral organoids. (baoninhsunrise.com)

Activator of protein kinase A (cyclic AMP agonist). (biolog.de)
Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. (bvsalud.org)

We further show that the cyclic AMP-dependent protein kinase (protein kinase A [PKA]) pathway maintains the cytoplasmic localization of Sip1 in glucose-grown cells. (elsevierpure.com)
The cyclic AMP-dependent protein kinase A signaling pathway plays a major role in regulating plant infection from the rice blast fungus and or are both necessary for development of spores and appressoria by and play roles in cell wall differentiation, regulating melanin pigmentation and cell surface hydrophobicity during spore formation. (bio2009.org)
Recently, we reported that MoRic8 interacts with MagB and functions upstream of the cAMP/PKA pathway to regulate multiple phases of infection-related morphogenesis in [56]. (bio2009.org)
However, downstream targets of the cAMP/PKA pathway are not well analyzed in and and are regulated by the cAMP/PKA pathway. (bio2009.org)
The cyclic GMP-AMP synthase (cGAS)-Stimulator of Interferon Genes (STING) pathway is a critical defender to sense various pathogens and trigger innate immunity of mammalian cells. (frontiersin.org)
We further show that upon cell surface stimulation, coronin 1 interacted with the G protein subtype Gαs to stimulate the cAMP/PKA pathway. (pasteur.fr)
The aryl hydrocarbon receptor (AhR), a member of the bHLH-Per-Arnt-Sim subfamily, is a ligand-activated transcription factor reported to regulate nervous system development in both invertebrates and vertebrates, but the functions that AhR signaling pathway may have for mammalian cerebral cortex development remains elusive. (waseda.jp)
These findings identify a new growth factor and stress-activated signaling pathway that regulates gene expression at the CRE. (dundee.ac.uk)

Immediate activation of chemosensory neuron gene expression by bacterial metabolites is selectively induced by distinct cyclic GMP-dependent pathways in Caenorhabditis elegans. (harvard.edu)
Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency. (harvard.edu)

In addition to cleavage of NAD + to Nam and ADP-ribose, NADases found in animals act as ADP-ribosylcyclases, generating cyclic ADP-ribose (cADPR), a potent intracellular Ca 2+ mobilizing agent 7 . (nature.com)
Vasoconstrictor-driven G protein-coupled receptor (GPCR)/phospholipase C (PLC) signaling increases intracellular Ca2+ concentration to mediate arterial contraction. (bvsalud.org)
We have hypothesized that intracellular AKAP350-coordinated complexes regulate both trafficking through the Golgi apparatus and processing of discrete RNA species within cytosolic domains. (grantome.com)
These complexes appear to coordinate the movement intracellular proteins and messenger RNAs responsible for far ranging processes within cells. (grantome.com)

Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation. (harvard.edu)

Here, endogenous GRK isoenzymes and arrestin proteins were selectively depleted using RNA-interference in rat arterial smooth muscle cells (RASM) and the consequences of this for ß2AR- and A2BR-mediated adenylyl cyclase (AC) signalling were determined by assessing cAMP accumulation. (bvsalud.org)

Our data suggest a specific role for mitochondria in regulating synaptic strength. (nih.gov)
Electrophysiological analysis of excitatory synaptic transmission in amygdala revealed that coronin 1 was essential for cyclic-AMP-protein kinase A-dependent presynaptic plasticity. (pasteur.fr)

The cAMP receptor protein of Escherichia coli, CRP, was employed as a model system to elucidate the functional roles of these loops. (utmb.edu)
Thus, the roles played by loop 3 in CRP may represent a more common mechanism employed by cyclic nucleotide binding domain in modulating ligand binding affinity and intramolecular communication. (utmb.edu)
Chen, R & Lee, JC 2003, ' Functional roles of loops 3 and 4 in the cyclic nucleotide binding domain of cyclic AMP receptor protein from Escherichia coli ', Journal of Biological Chemistry , vol. 278, no. 15, pp. 13235-13243. (utmb.edu)

For instance, due to their genetic flexibility, viruses have developed various viral proteins and non-coding RNAs to interrupt several checkpoints of cGAS-STING. (frontiersin.org)
We have learned that genes in mammalian cells are transcribed into messenger RNAs (mRNAs), which are to be translated into polypeptides (proteins). (intechopen.com)

The new features significantly enhance the ability of Predikin to analyse protein kinases and their substrates. (biomedcentral.com)
In general, a protein kinase acts on a discrete set of substrates to ensure that signalling fidelity is maintained. (biomedcentral.com)

In this research project, we have investigated the C-terminal structures of small G proteins, purified the regulatory proteins for small G proteins, and made monoclonal antibodies against small G proteins and their regulatory proteins. (nii.ac.jp)
Among these regulatory proteins, we have cloned the cDNAs of smg p21 GDS, smg p25A GDI, and rho GDI, and made monoclonal antibodies against them. (nii.ac.jp)

Pereyra, E. Mucor rouxii ultrastructure: Cyclic AMP and actin cytoskeleton. (uba.ar)
Moreno, S. 'Mucor rouxii ultrastructure: Cyclic AMP and actin cytoskeleton' (2006) Protoplasma. (uba.ar)

In the discovery set of fresh-frozen tissue specimens (14), the A-kinase anchor protein 12 (AKAP12) protein was found downregulated across the grades. (nature.com)

The 1.6 Å X-ray structure of the homodimeric A. fumigatus protein reveals unique properties including N-linked glycosylation and a Ca 2+ -binding site whose occupancy regulates activity. (nature.com)
The structure of the dimeric A. fumigatus enzyme revealed the presence of a Ca 2+ binding site whose occupancy partially regulates enzymatic activity. (nature.com)
Reducing PKA activity increased ATG16L1 protein levels and endothelial autophagy. (mdc-berlin.de)
This study found an increase in excess GR transcriptional activity of protein phosphatase 1 alpha (PP1α) in HEK-293 cells and a decrease in the expression levels of GR-responsive gene knockdown following PP1α model A549 cells endogenously . (pp1a.com)
Phosphoproteomic techniques have been widely employed to identify kinase activity, which may lend itself to pharmaceutical blockade. (nature.com)
There is a superfamily of ras p21/ras p21-like small GTP-binding proteins (small G proteins) with GTPase activity. (nii.ac.jp)

which encodes a putative G-protein-coupled receptor may be involved in regulating Mac pc1 activities, because is required for surface acknowledgement and virulence and exogenous cAMP restores appressorium formation and pathogenicity in deletion mutants [55]. (bio2009.org)

By acting as a ligand-dependent transcription factor of the glucocorticoid receptor (GR) mediates the action of glucocorticoids and regulates many physiological processes. (pp1a.com)

Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase. (musc.edu)
In yeasts, several downstream target proteins of PKA have also been recognized and functionally characterized. (bio2009.org)

We recently reported a procedure for inferring gene-regulatory network models by integrating gene-expression profiles with high-throughput measurements of protein interactions [ 18 ]. (biomedcentral.com)
Gene expression must be appropriately maintained to regulate development, differentiation, and proliferation of cells. (intechopen.com)

A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. (bvsalud.org)

Cyclic AMP is a ubiquitous secondary message that regulates a large variety of functions. (utmb.edu)

Based on the sequence differences between CRP and cyclic nucleotide gated channel, three mutants of CRP were constructed: deletion (residues 54-56 in loop 3 were deleted), insertion (loop 4 was lengthened by 5 residues between Glu-78 and Gly-79) and double mutants. (utmb.edu)
We have found that the C-terminal systeine residues of smg p21B, rhoA p21, and smg p25A are geranylgeranylated, and that these prenylation are essential for each small G protein to bind to membranes. (nii.ac.jp)

We here show an essential role for coronin 1, which is encoded in a genomic region associated with neurobehavioral dysfunction, in the modulation of cyclic AMP/PKA signaling. (pasteur.fr)

The circadian clock is an autonomous oscillator responsible for regulating physiology and behavior, thereby conferring adaptive advantage to living organisms by allowing them to anticipate regular changes in their environment. (jneurosci.org)

In both and Flo8 interacts with Efg1, a homolog of the Phd1/Sok2 and StuA proteins that regulate morphogenesis of and FoStuA, GcStuA and MoStu1 (Mstu1), have recently been recognized [29]C[31]. (bio2009.org)

Below are the most recent publications written about "Cyclic AMP-Dependent Protein Kinase Type II" by people in Profiles. (uchicago.edu)

The Snf1 catalytic subunit also exhibits aberrant localization to the vacuolar membrane in PKA-deficient cells, indicating that PKA regulates the localization of Snf1-Sip1 protein kinase. (elsevierpure.com)

This regulates their acute responses and chronic adaptations to the acidic pH e microenvironment. (biomedcentral.com)

Anatomy19

Organisms13

Chemicals and Drugs165

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Phenomena and Processes43

Information Science3

Phosphorylation20

CAMP-depend5

Isoforms4

Phosphodiesterases2

Receptors10

Activates5

Dopamine1

Inhibitors1

Glycogen3

Regulation4

SERINE2

Metabolism1

Phosphodiesterase2

MeSH1

Neuronal1

Specificity5

Substrate4

Subcellular2

Cardiac4

Subunits3

Dynamin-related protein2

DRP11

Cellular6

Calcium1

Differentially2

Activator2

Pathway8

Pathways2

Intracellular4

Mechanisms1

Selectively1

Synaptic2

Roles3

RNAs2

Substrates2

Regulatory proteins2

Ultrastructure2

Anchor protein1

Activity6

Putative1

Transcription Factor1

Functionally2

Gene2

Promoters1

Ubiquitous1

Residues2

Modulation1

Behavior1

Morphogenesis1

Profiles1

Catalytic1

Responses1