ApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsMammalsDNA FragmentationIn Situ Nick-End LabelingCell Line, Tumorbcl-2-Associated X ProteinSignal TransductionX-Linked Inhibitor of Apoptosis ProteinCell SurvivalCell LineCells, CulturedApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinMolecular Sequence DataMitochondriaCaspase 9Caspase InhibitorsEnzyme ActivationCaspase 8Tumor Suppressor Protein p53Tumor Cells, CulturedFas Ligand ProteinBlotting, WesternAmino Acid SequenceTransfectionCytochromes cCell Proliferationbcl-X ProteinCell CycleAnnexin A5Proto-Oncogene ProteinsRNA, MessengerFlow CytometryHeLa CellsCysteine Proteinase InhibitorsBase SequenceAmino Acid Chloromethyl KetonesEnzyme InhibitorsPhosphorylationAntineoplastic AgentsRNA, Small InterferingPoly(ADP-ribose) PolymerasesCarrier ProteinsDose-Response Relationship, DrugReactive Oxygen SpeciesJurkat CellsTime FactorsGene Expression RegulationDown-RegulationMutationDNA DamageMice, Inbred C57BLTNF-Related Apoptosis-Inducing LigandCell DeathProtein BindingHL-60 CellsMembrane ProteinsEmbryo, MammalianMembrane GlycoproteinsDNA-Binding ProteinsProtein-Serine-Threonine KinasesReverse Transcriptase Polymerase Chain ReactionCell DivisionCaspase 7Transcription FactorsMembrane Potential, MitochondrialGene ExpressionMice, KnockoutProto-Oncogene Proteins c-aktModels, BiologicalRecombinant ProteinsTumor Necrosis Factor-alphaRNA InterferenceUp-RegulationSequence Homology, Amino AcidCell NucleusGenes, bcl-2ProteinsTOR Serine-Threonine KinasesNuclear ProteinsImmunohistochemistrybcl-2 Homologous Antagonist-Killer ProteinCytochrome c GroupNecrosisNF-kappa BDNAMyeloid Cell Leukemia Sequence 1 ProteinFibroblastsCricetinaeBH3 Interacting Domain Death Agonist ProteinCloning, MolecularStaurosporineGene Expression Regulation, NeoplasticCysteine EndopeptidasesTranscription, Genetic