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  • Cytoplasmic
  • In the normal WT retinas, p27 was localized to the nuclei of RPE cells while nuclear and cytoplasmic p27 was detected in RPE cells undergoing EMT, suggesting a role for cytoplasmic p27 in the phenotype changes of RPE cells. (molvis.org)
  • transcription
  • E2A and HEB are structurally and functionally related basic helix-loop-helix transcription factors involved in T cell development. (jimmunol.org)
  • mammalian
  • However, although diverse physiological effects have been documented for this compound, curcumin's mechanism of action on mammalian cells remains unclear. (asm.org)
  • inactivation
  • The design of therapeutic strategies to reinstitute immune tolerance, however, is hampered by uncertainty regarding the molecular mechanisms involved in the inactivation of potentially autoreactive T cells. (biomedcentral.com)
  • CDK6
  • MicroRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma. (thefreedictionary.com)
  • substrates
  • Membrane potential-dependent transport of essential metabolic substrates during the cell cycle and/or volume regulation could also play a role (for review, see Wonderlin and Strobl, 1996 ). (jneurosci.org)
  • Neural
  • Neural stem cells (NSCs) isolated from embryonic cortex are characterized by their ability of self-renewal under continued maintenance of multipotency. (oregonstate.edu)
  • Arrests the Cell Cycle
  • For example, the G2-M DNA damage checkpoint ensures the fidelity of DNA replication, and arrests the cell cycle to allow time for replication error correction and DNA damage repair. (qiagen.com)