Regions physiological differences in brain. Medical search. Frequent questions

Here, we challenge that unified view with convergent anatomical and physiological results from rhesus macaques. (nature.com)
It is well known that enriched or complex stimular environments affect CNS at both anatomical and physiological levels. (psicothema.com)
However, certain gene classes including neurotransmitter release and reuptake as well as synapse turnover, harbor significant variability in the same cell type across anatomical regions, suggesting differences in network activity may influence cell-type identity. (biorxiv.org)
The same cell type traced across development shows more isoform variability than across adult anatomical regions, indicating a coordinated modulation of functional programs dictating neural development. (biorxiv.org)
However, a translational barrier exists between rodents and humans because of the anatomical and physiological differences between the two species. (en-journal.org)
Understanding the anatomical, physiological, behavioral, and computational bases for the development and expression of multisensory integration. (wakehealth.edu)
The overall goal is to scientifically explain all the connections - both anatomical and wireless - that activate different brain regions during cognitive tasks. (mightynatural.com)

To study the interplay of metabolic state (hungry vs. satiated) and glucose administration (including hormonal modulation) on brain function, resting-state functional magnetic resonance imaging (rs-fMRI) and blood samples were obtained in 24 healthy normal-weight men in a repeated measurement design. (frontiersin.org)
Several studies using rs-fMRI revealed associations of insulin or glucose levels with the functional connectivity (FC) of particular brain networks or brain sites that are related to homeostatic regulation but not without contradictions. (frontiersin.org)
Functional magnetic resonance imaging was used to determine brain areas associated with steadiness and force during static (isometric) lower limb target-matching contractions at low and high intensities. (cdc.gov)
Single photon emission computed tomography (SPECT) -- a scanning method less distracting than functional magnetic resonance imaging (fMRI) -- showed IBMT subjects had increased blood flow in the right anterior cingulate cortex, a region associated with self regulation of cognition and emotion. (eurekalert.org)
For example, participants were shown pictures of yummy, high-calorie foods (candy, cookies, pizza, and juicy burgers) while their brains were scanned via functional magnetic resonance imaging. (nationalgeographic.com)
These two subregions have notable functional differences. (nature.com)
they are instead due to the circuitry and functional organization of the brain, as well as to inappropriate experimental protocols that ignore this organization. (freethoughtblogs.com)
Resting fMRI has potential for assessing brain function independently from a task, but greater understanding of how networks of resting functional connectivity relate to the functioning of the brain is needed. (ox.ac.uk)
this overlapped with increased resting fMRI functional connectivity in the same regions. (ox.ac.uk)
Specifically , "The term 'cognitive reserve' is thus meant to represent physiological robustness within functional brain networks, while the term 'brain reserve' refers to differences in available structural neural substrates. (bigthink.com)
Physiological and behavioral studies have revealed that SC multisensory integration depends on the functional integrity of converging projections that descend from different regions of association cortex. (wakehealth.edu)
And they're getting better at recording how information moves through the brain by using enhanced functional magnetic resonance imaging to measure blood flow. (mightynatural.com)

To avoid these disadvantages in the present investigation, we used resting-state fMRI in order to reveal potential links between whole brain activity and insulin and glucose levels in different metabolic states. (frontiersin.org)
According to the late neuroscientist Oliver Sacks, M.D., fMRI scans demonstrate that brains of musicians appear and function differently (and more effectively) than the brains of people who are not engaged with music. (nymetroparents.com)
The magnitude of the fMRI signal cannot be quantified to reflect accurately differences between brain regions, or between tasks within the same region. (freethoughtblogs.com)
Task fMRI data were acquired during the execution of a memory paradigm designed to account for differences in task performance. (ox.ac.uk)
Structural and physiological confounds were modeled for both fMRI modalities. (ox.ac.uk)
CONCLUSIONS: Our results show that task fMRI and resting fMRI are sensitive markers of residual ability over the known changes in brain morphology and cognition occurring in AD and suggest that resting fMRI has a potential to measure the effect of new treatments. (ox.ac.uk)
fMRI analysis revealed that analgesia was related to decreased brain activity in pain-related brain regions, including the lingual and parahippocampal gyrus. (jneurosci.org)

The contention about individual differences between men with different cognitive ability related with differences in cerebral structures has prompted the design of a number of experiments (Rosenzweig, 1979) and whether animals exposed to enriched environments differ with respect to their behaviour, neuroanatomy and neurochemistry from those brought up in an impoverished environment (Bennet et al. (psicothema.com)
Brain reserve specifically references individual differences in the brain's structural properties that affords one resilience against neurodegenerative diseases. (bigthink.com)
The authors first showed that individual differences in asymmetric frontal electrical activity are a stable characteristic. (virginia.edu)
In addition, individual differences in CSF CRH concentrations were stable from 4 to 52 months of age. (virginia.edu)
Therefore, the following review integrates neuroimaging research related to factors that may impact symptom expression in asthma, such as individual differences in sensitivity to visceral signals, the influence of expectation and emotion on symptom perception, and changes related to disease chronicity, such as conditioning and plasticity. (virginia.edu)
There are also new findings on the physiological predictors of individual differences in emotional behavior and experience, and on the role of autonomic arousal in emotional memory. (virginia.edu)

The underlying brain mechanisms, however, are unclear. (jneurosci.org)
These findings have implications for the underlying brain mechanisms of psychological analgesia. (jneurosci.org)
The finding of regional abnormalities specific to individual conditions, Dr. Opel added, "could help shift the focus of future psychiatric and neuroscientific research on brain regions that appear to be central to disorder-specific biological processes and hence might facilitate the discovery of mechanisms underlying the development of specific psychiatric disorders. (neurosciencenews.com)
Name physiological mechanisms where transport is operational? (fsu.edu)
Recent technological advances enable us to investigate whether similar mechanisms underlie aging and neurodegeneration, by quantifying the similarities and differences in their genome-wide gene expression profiles. (lisanwanglab.org)
CONCLUSIONS: This study establishes a quantitative scale for measuring premature aging in neurodegenerative disease cohorts, and it identifies specific physiological mechanisms common to aging and some forms of neurodegeneration. (lisanwanglab.org)
Affective style, psychopathology, and resilience: Brain mechanisms and plasticity. (virginia.edu)

Neural activity in the subgenual prefrontal cortex, a brain region active during rumination - repetitive thought focused on negative emotions - decreased among participants who walked in nature versus those who walked in an urban environment. (timberry.com)
But recent findings in brain scans and neuroscience underline just how profound these benefits are to a child's rapidly developing neural networks. (nymetroparents.com)
By analyzing scans of the auditory cortex and grouping clusters of brain cells with similar activation patterns, the MIT scientists have identified neural pathways that react almost exclusively to the sound of music-any music. (nymetroparents.com)
In this sense, playing music is akin to cross-circuit training for the brain-exercise that builds stronger and denser neural networks that can then be activated in tasks related to language, sequencing, and mathematical operations. (nymetroparents.com)
The Brigham and Women's Hospital (BWH) and Harvard Medical School (HMS) SCORE is advancing our understanding of stress exposures and neural regulation of reproductive aging health outcomes, and catalyzing growth of translational women's health and sex-differences research in aging women. (nih.gov)
1994). Animals reared in enriched environments have been demonstrated to learn more quickly in behavioural tests and present, in comparison with animals reared in an impoverished environment, increased brain weight, neural size, dendritic extension, glial proliferation and activity of certain neurotransmitters such as cortical acetylcholine (Parks et al. (psicothema.com)
As with physical exercise, brain exercises keep your neural connections growing. (bigthink.com)

A new study has found that long-term use of anabolic steroids can lead to significant brain structural changes and cognitive impairment. (swacift.org)
Comparing data from multiple neuroimaging studies, researchers found shared brain structural abnormalities between four psychiatric disorders, including schizophrenia and bipolar disorder. (neurosciencenews.com)
Researchers have previously identified brain structural signatures associated with individual neurological diseases using techniques such as magnetic resonance imaging (MRI). (neurosciencenews.com)
In a new study, a team of scientists based in Germany has compared data from multiple studies to find brain structural abnormalities shared between four different neuropsychiatric conditions. (neurosciencenews.com)
Co-first author Nils Opel, MD, (together with Janik Goltermann, MSc) said of the work, "the identification of shared and disorder-specific brain structural signatures might enhance the future development of biologically informed diagnostic applications in psychiatry. (neurosciencenews.com)
We found that 4 major psychiatric disorders - major depression, bipolar disorder, schizophrenia, and obsessive-compulsive disorder - show a surprisingly high level of similarity in their brain structural abnormalities," said Dr. Opel. (neurosciencenews.com)
The shared brain areas showing structural aberrations were mainly in cortical areas associated with cognitive processing, memory and self-awareness. (neurosciencenews.com)
Interestingly, these distinct structural differences sometimes appeared in the same area for two disorders, but in opposite directions from the norm. (neurosciencenews.com)
In contrast, attention-deficit/hyperactivity disorder and autism spectrum disorder did not share brain structural signatures with any other disorders. (neurosciencenews.com)
"Cross-Disorder Analysis of Brain Structural Abnormalities in Six Major Psychiatric Disorders: A Secondary Analysis of Mega- and Meta-analytical Findings From the ENIGMA Consortium" by Bernhard T. Baune et al. (neurosciencenews.com)
Neuroimaging studies have consistently reported similar brain structural abnormalities across different psychiatric disorders. (neurosciencenews.com)
Here, we conducted a cross-disorder analysis of brain structural abnormalities in 6 psychiatric disorders based on effect size estimates for cortical thickness and subcortical volume differences between healthy control subjects and psychiatric patients from 11 mega- and meta-analyses from the ENIGMA (Enhancing Neuro Imaging Genetics Through Meta Analysis) consortium. (neurosciencenews.com)

PRINCIPAL FINDINGS: We have developed a computational method for assessing an individual's "physiological brain age" by comparing global mRNA expression datasets across a range of normal human brain samples. (lisanwanglab.org)

HCG, der anvendes pa en bestemt made i lobet af de forste 1-2 uger med PCT i en dosis pa 100-1, anabolic steroids effects on cognition. (swacift.org)
This concept refers to one's ability to improvise in order to maintain healthy cognition, which requires co-opting other brain regions to accomplish new tasks. (bigthink.com)

Glial brain-region specificity in isoform expression includes strong poly(A)-site regulation, whereas neurons have stronger TSS regulation. (biorxiv.org)
In cortical regions in which stimulus- or task-related perceptual or cognitive capacities are sparsely represented (for example, instantiated in the activity of a very small number of neurons), volume transmission- which probably underlies the altered states of motivation, attention, learning and memory-may dominate haemodynamic responses and make it impossible to deduce the exact role of the area in the task at hand. (freethoughtblogs.com)
The cerebellum is also the brain region that contains the highest number of neurons. (bigthink.com)
Anatomy alone - the neurons and nerve fibers - cannot explain the excitation of these regions, concurrently or in tandem. (mightynatural.com)
In the case of the brain, nerve cells conduct electrical impulses down long threadlike arms called axons from the cell body to other neurons. (mightynatural.com)
Brain function relies on communication between large populations of neurons across multiple brain areas, a full understanding of which would require knowledge of the time-varying activity of all neurons in the central nervous system. (zotero.org)
Here we use light-sheet microscopy to record activity, reported through the genetically encoded calcium indicator GCaMP5G, from the entire volume of the brain of the larval zebrafish in vivo at 0.8 Hz, capturing more than 80% of all neurons at single-cell resolution. (zotero.org)
Demonstrating how this technique can be used to reveal functionally defined circuits across the brain, we identify two populations of neurons with correlated activity patterns. (zotero.org)
Understanding the mechanism by which the brain’s hundred billion neurons and hundred trillion synapses manage to produce such a range of cortical configurations in a flexible manner remains a fundamental problem in neuroscience. (zotero.org)

Each SCORE program serves as a national resource for translational research, at multiple levels of analysis, to identify the role of biological sex differences on the health of women. (nih.gov)
In this review, we explore the role of biological sex in the development of the brain and analyze its impact on the predisposition toward and the progression of neurodegenerative diseases. (mdpi.com)

The results seem to show integration -- a connectivity of brain and body. (eurekalert.org)
We hypothesized that the key to understanding the role of cOFC in the transformations associated with choice is through its connectivity with another region involved in economic choice: the posterior cingulate cortex (PCC). (nature.com)
Physiological connectivity developed between the ipsilateral cerebral hemisphere and the paralyzed hand. (medscape.com)

Thus animals under isoleted environment show disorders of physiological parameters related with stress (Gardiner and Bennett, 1977). (psicothema.com)
The bed nucleus of the stria terminalis (BNST) is a sexually dimorphic brain region which plays a key role in stress, anxiety, and anxiety-related disorders. (exeter.ac.uk)
Human females have an increased susceptibility to anxiety-related disorders, however the physiological basis of this is not fully understood. (exeter.ac.uk)
These sex-specific differences in excitability may contribute to altered susceptibility to anxiety-related disorders. (exeter.ac.uk)
Our understanding arising from brain imaging studies of the biology of neuropsychiatric disorders is changing," said John H. Krystal, MD, Editor of Biological Psychiatry. (neurosciencenews.com)
BACKGROUND: Human brain aging has received special attention in part because of the elevated risks of neurodegenerative disorders such as Alzheimer's disease in seniors. (lisanwanglab.org)
January 10, 2023 - Notice of Information to Expire the PAR-21-311, Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional). (nih.gov)
February 9, 2022 - Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional). (nih.gov)
This Funding Opportunity Announcement (FOA) encourages grant applications for the conduct of innovative, collaborative research projects with low- and middle-income country (LMIC) institutions/ scientists on brain and other nervous system function and disorders throughout life, relevant to LMICs. (nih.gov)

Much research has detected physiological abnormalities in fibromyalgia, including increased levels of substance P in the spinal cord, low levels of blood flow to the thalamus region of the brain, HPA axis hypofunction, low levels of serotonin and tryptophan, and abnormalities in cytokine function. (belmarrahealth.com)

In addition to behavioral and theoretical analyses of episodic memory, we also explore the neurophysiology of episodic memory with electrocorticographic (ECoG) and single neuron recordings from neurosurgical patients who have had electrodes surgically implanted on the cortical surface of the brain or through the medial temporal lobes (including hippocampus) as part of the clinical process of localizing seizure foci. (upenn.edu)
Indeed, while the physiological damage can be repaired following cessation of steroid use, behavioral damage takes much longer to heal. (swacift.org)
We are investigating this question at physiological and behavioral levels. (wakehealth.edu)
Data from other preclinical studies suggests that the increased brain CRH activity may underlie the behavioral and physiological characteristics of fearful endophenotype. (virginia.edu)

Although maintenance of steady contractions is required for many daily tasks, there is little understanding of brain areas that modulate lower limb force accuracy. (cdc.gov)
There were minimal sex differences in brain activation across the isometric motor tasks indicating men and women were similarly motivated and able to activate cortical motor centers during static tasks. (cdc.gov)
There are other instances of teachers returning to work after having a stroke even though brain tissue associated with cognitive tasks has been destroyed. (bigthink.com)
Their brains routed those tasks through other regions. (bigthink.com)

Located at the rear of the brain, the cerebellum plays an essential role in motor control in humans. (bigthink.com)
We investigated the effect of task differences on the ability of three models of saliency to predict the performance of humans viewing a novel database of 800 natural images. (zotero.org)

Before and after, the researchers measured heart and respiration rates, performed brain scans and had participants fill out questionnaires. (timberry.com)
Even after one year of music study, astounding physical changes can be seen when before and after brain scans are compared. (nymetroparents.com)
MRI scans show that depressed individuals have differences in brain appearance, especially in the regions that are related to sleep, mood, thinking, appetite, and behavior. (theperfectworkout.com)
The research team used scans to compare the brains of people who had used anabolic steroids for at least two years with those who had never taken them. (swacift.org)

The new findings, he said, point to how IBMT alters blood flow and electrical activity in the brain, breathing quality and even skin conductance, allowing for "a state of ah, much like in the morning opening your eyes, looking outside the grass and sunshine, you feel relaxed, calm and refresh without any stress, this is the meditation state. (eurekalert.org)
Our findings shed light in the mode of the transcriptional changes occurring in the brain during aging and suggest that strategies aiming to broader but more modest changes in gene expression may be preferrable to correct aging-associated deregulation in gene expression. (nsf.gov)
These findings illustrate the utility of using facial behavior to verify the presence of emotion, are consistent with the notion of emotion-specific physiological patterning, and underscore the importance of anterior cerebral asymmetries for emotions associated with approach and withdrawal. (virginia.edu)
CONCLUSIONS: These findings suggest that, in primates, the fearful endophenotype is characterized by increased fearful behavior, a specific pattern of frontal electrical activity, increased pituitary-adrenal activity, and increased activity of brain CRH systems. (virginia.edu)
The findings suggest iodine sufficiency at the national level, however southern region still has a goitre prevalence of mild degree severity and the proportion of households consuming adequately iodized salt is still below recommendations. (who.int)

We observed a modulatory impact of fasting state on intrinsic brain activity in the posterior cingulate cortex (PCC). (frontiersin.org)

This is an astounding finding, as it shows that we all have a distinct area in our brains that is closely mapped to the domain of music. (nymetroparents.com)
Cognitive functions such as reasoning and learning use a number of distinct brain regions in a time-sequenced manner. (mightynatural.com)
The data point to a set of behaviors and changes in gene expression following postnatal deletion of TrkB in the dorsal striatum distinct from those in other brain regions. (biomedcentral.com)

It's imaging the broader physiological activity - respiration, oxygen flux, vascular changes - in small chunks of the brain. (freethoughtblogs.com)

People who are adept at any or all of the six skills below have a strong brain reserve, and therefore can recover from insults to the brain such as neurodegenerative disease. (bigthink.com)

Using multiple linear regression analysis (MLRA) the interdependence of brain activity, plasma insulin and blood glucose was investigated. (frontiersin.org)
Strikingly, differences in plasma insulin levels between hunger and satiety states after glucose administration at the time of the scan were negatively related to brain activity in the posterior insula and superior frontal gyrus (SFG), while plasma glucose levels were positively associated with activity changes in the fusiform gyrus. (frontiersin.org)
FALFF is a reliable index of spontaneous brain activity. (frontiersin.org)
and their brains, while viewing luscious pictures of food, showed greater activity in regions associated with attention and reward. (nationalgeographic.com)
The results show a significant increase of CO activity in all of the regions studied in the isolated group, with differences among the studied hippocampal regions in both groups. (psicothema.com)
A study led by Stanford researcher Gregory Bratman showed that people who walked for 90 minutes in a natural area, as opposed to participants who walked in a high-traffic urban setting, had decreased activity in a region of the brain associated with a key factor in depression. (mindfood.com)
At some point during the syndrome's development, both show evidence of edema, changes in skin blood flow revealed by color changes and skin temperature changes greater than 1.1°C from the homologous body part, or abnormal sudomotor activity in the painful region. (medscape.com)
In this experiment, we combined the measurement of observable facial behavior with simultaneous measures of brain electrical activity to assess patterns of hemispheric activation in different regions during the experience of happiness and disgust. (virginia.edu)
When data aggregated across positive films were compared to aggregate negative film data, no reliable differences in brain activity were found. (virginia.edu)
BACKGROUND: Asymmetric patterns of frontal brain activity and brain corticotropin-releasing hormone (CRH) systems have both been separately implicated in the processing of normal and abnormal emotional responses. (virginia.edu)
Previous studies in rhesus monkeys demonstrated that individuals with extreme right frontal asymmetric brain electrical activity have high levels of trait-like fearful behavior and increased plasma cortisol concentrations. (virginia.edu)
METHODS: In this study we assessed cerebrospinal fluid (CSF) CRH concentrations in monkeys with extreme left and extreme right frontal brain electrical activity. (virginia.edu)
RESULTS: Monkeys with extreme right frontal brain activity had increased CSF CRH concentrations at all ages measured. (virginia.edu)
A large repertoire of spatiotemporal activity patterns in the brain is the basis for adaptive behaviour. (zotero.org)
Current sleep study evidence suggests that even before first tooth contact a series of physiological events occur which include activation of the autonomic cardiac system at minus 4 minutes, brain activity at minus four seconds, a rise in jaw opener muscle tone with 2 big breaths, and an increase in heart rate at minus one second. (medscape.com)

Our results indicate that hormonal signals like insulin alleviate an acute hemostatic energy deficit by modifying the homeostatic and frontal circuitry of the human brain. (frontiersin.org)
Furthermore, fructose doesn't stimulate insulin secretion or leptin production, which together send signals to the brain that suppress appetite by telling the body it's had enough to eat. (nationalgeographic.com)
Here at the Global Center for Neurological Networks we're focusing on how these wireless signals work in the brain to communicate information. (mightynatural.com)
Border ownership signals that model physiological observations arise through finite range, intraareal interactions. (zotero.org)

Self-inflicted wound or self-inflicted injury refers to a broader range of circumstances, including wounds that result from organic brain syndromes, substance abuse, and autoeroticism. (wikipedia.org)

Fortunately, I can just tell you to go read Christian Jarrett, who explains most of the flaws in the study , or you can look at these graphical illustrations of the magnitude of the differences . (freethoughtblogs.com)
The magnitude of the physiological impact of integration at the single neuron level has traditionally been measured as a change (usually expressed as a % change) in the total number of stimulus-elicited impulses. (wakehealth.edu)

Attention continues to focus on the amygdala and its interconnections with prefrontal cortical regions. (virginia.edu)

The synthesis of these literatures suggests that the insular and anterior cingulate cortices, in addition to other brain regions previously implicated in the regulation of emotion, may be both responsive to asthma-related bodily changes and important in influencing the appearance and persistence of symptom expression in asthma. (virginia.edu)
The brain circuitry underlying emotion includes several territories of the prefrontal cortex (PFC), the amygdala, hippocampus, anterior cingulate, and related structures. (virginia.edu)

A key finding from recent research is that the prefrontal cortex - responsible for EF skills like focus, planning, and self-control - is closely linked to brain regions that are responsible for signaling emotions like fear, anger, and anxiety [11] [12] . (aspeninstitute.org)

Metabolic state, insulin levels and glucose administration interact in their effects on brain activation patterns. (frontiersin.org)
The disease is likely caused by some combination of thought patterns and biological, genetic, environmental, and physiological factors. (theperfectworkout.com)
Your brain is flexible enough to change operational patterns to deal with challenges in novel ways. (bigthink.com)
Behaviour of mutation load also exhibits gender differences and late-life reversals, explaining some gender-specific and late-life patterns in cancer incidence rates. (who.int)

26. What physiological processes are in common for all neuron types? (fsu.edu)
The high affinity tyrosine kinase receptor, TrkB, is the primary receptor for brain derived neurotrophic factor (BDNF) and plays an important role in development, maintenance and plasticity of the striatal output medium size spiny neuron. (biomedcentral.com)

This is important as numerous forms of brain plasticity occur there. (bigthink.com)

Once infected by CWD, the CWD prions will induce normal brain proteins to change abnormally. (ubc.ca)
After enough brain proteins were infected, the brain will become "empty", and can't work as usual. (ubc.ca)

By applying our method to rat hippocampal data, we show that the types of estimated connections match the results inferred from other physiological cues. (nature.com)
For the experimental data, we compare our estimates of whether an innervating connection is excitatory or inhibitory with the results obtained by manually analyzing other physiological information such as spike waveforms, autocorrelograms, and mean firing rate. (nature.com)
Subgroup analysis stratified according to comorbidity, lifestyle, family structure, publication year, and region showed statistical differences between groups, and the consistency of the results revealed the sources of the heterogeneity. (frontiersin.org)
These results suggest sex differences in SON gene expression that are associated with cell signaling and ribosomal pathways. (bvsalud.org)
The results showed apparent differences in the size and shape of specific brain regions between the groups, köpa steroider 2022. (swacift.org)
Our results suggest that the cortical OFF pathway is faster than the ON pathway at increasing and suppressing visual responses, and these differences have parallels in the human visual perception of lights and darks. (zotero.org)
We review recent theoretical and empirical results supporting the notion that the brain is naturally poised near criticality, as well as its implications for better understanding of the brain. (zotero.org)

The Specialized Centers of Research Excellence (SCORE) on Sex Differences program is a signature program of the Office of Research on Women's Health (ORWH). (nih.gov)
SCORE investigators provide leadership in the development and promotion of standards and policies for the consideration of sex as a biological variable (SABV) and sex differences in biomedical research. (nih.gov)
The current SCORE U54 program leverages over 15 years of our prior investment to create a disease-agnostic research program focused on sex differences and major medical conditions affecting women in the U.S. The former Specialized Centers of Research (SCOR) P50 program funded established scientists at centers across the country, with support from our NIH Institute and Center (IC) partners. (nih.gov)
Basic, clinical, and translational research approaches led to seminal contributions to the study of sex differences related to women's health. (nih.gov)
The current ORWH SCORE program remains the only NIH centers program supporting disease-agnostic research on sex differences. (nih.gov)
ORWH published the Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional) request for applications (RFA), RFA-OD-18-004 , in fiscal year (FY) 2018 and funded six new awards. (nih.gov)
The Career Enhancement Core is a new feature of the program whose goal is to support pilot research and train the next generation of scientists in the study of sex differences. (nih.gov)
As NIH-supported Centers of Excellence, the SCORE program's centers provide leadership and serve as a resource in the development and promotion of standards and policies for the consideration of sex differences in biomedical research. (nih.gov)
Stroke research in non-human primates (NHPs) with gyrencephalic brains is a critical step in overcoming the translational barrier that limits the development of new pharmaceutical and rehabilitative strategies for stroke. (en-journal.org)
The team analyzed data collected as part of the effort by an international research consortium called ENIGMA, for "Enhancing Neuro Imaging Genetics through Meta Analysis," which uses genetic and imaging studies to understand brain diseases. (neurosciencenews.com)
To address this shortcoming, my team's bioengineering research focuses on relationships between brain structure and function. (mightynatural.com)
Research suggests that chronic exposure to poverty-related stressors can change the basic architecture of the brain, particularly the areas responsible for learning, memory, planning, and self-control [14] . (aspeninstitute.org)
The collaborative research programs are expected to contribute to the long-term goals of building and strengthening sustainable neuro-health research capacity in LMICs to address brain, nervous system and neuromuscular development, function and impairment throughout life and to lead to diagnostics, treatments, prevention and implementation strategies. (nih.gov)

Respiratory which inhalation dosimetric relationships contribute to this tract uptake of halothane, acetone, ethanol and diacetyl was species difference in regional airway injury is not known, but measured in male F344 rat to obtain data for model validation. (cdc.gov)

Brain areas relevant for ingestive behavior are modulated as a function of hunger/satiety. (frontiersin.org)
Prior work has largely assumed that the cOFC is a single region with a single function. (nature.com)
However, human brains have evolved additional cell-type specificity in splicing, suggesting gain-of-function isoforms. (biorxiv.org)
decrementing, what is their physiological function? (fsu.edu)
We're working on complex models that better capture what scientists know of brain function. (mightynatural.com)
Ultimately a clearer picture of structure and function may fine-tune the ways brain surgery attempts to correct structure and, conversely, medication tries to correct function. (mightynatural.com)
Where the conventional model uses a circular symmetric Gaussian function to describe the pRF, the new model uses a circular symmetric difference-of-Gaussians (DoG) function. (zotero.org)

As most cell-type specific exons in P56 mouse hippocampus behave similarly in newly generated data from human hippocampi, these principles may be extrapolated to human brain. (biorxiv.org)
physiological principles? (fsu.edu)

Sex differences in SON gene expression have been relatively unexplored. (bvsalud.org)
This study aimed to address this knowledge gap using spatial transcriptomics to test for sex-based differences in gene expression in the supraoptic nucleus. (bvsalud.org)

semester time - and so I didn't have time to comment on this recent PNAS paper that reports on dramatic sex differences in the brains of men and women. (freethoughtblogs.com)

While both groups experienced some benefit from the training, those in IBMT showed dramatic differences based on brain-imaging and physiological testing. (eurekalert.org)

This one found no significant difference between walking inside vs. walking outside, but noted a big advantage to walking vs. sitting. (timberry.com)
Application of this method to brains samples from select regions in two diseases-Alzheimer's disease (AD, superior frontal gyrus), frontotemporal lobar degeneration (FTLD, in rostral aspect of frontal cortex ∼BA10)-showed that while control cohorts exhibited no significant difference between physiological and chronological ages, FTLD and AD exhibited prematurely aged expression profiles. (lisanwanglab.org)
Significant sex and/or genotype differences were found in the forced swim test of depression-like behaviors, anxiety-like behaviors on the elevated plus maze, and cocaine conditioned reward. (biomedcentral.com)

Using enhanced long-read single-cell isoform sequencing, we comprehensively analyze RNA isoforms in multiple mouse brain regions, cell subtypes, and developmental timepoints from postnatal day 14 (P14) to adult (P56). (biorxiv.org)
Cox proportional hazard model was used to analyze travel time differences for colon versus rectal cancer patients. (cdc.gov)

People with large brain reserves can circumvent Alzheimer's. (bigthink.com)
Interaction Analysis Reveals Complex Genetic Associations with Alzheimer's Disease in the CLU and ABCA7 Gene Regions. (cdc.gov)
Voxel Extraction and Multiclass Classification of Identified Brain Regions across Various Stages of Alzheimer's Disease Using Machine Learning Approaches. (cdc.gov)

In a recent study at MIT, scientists note that music sensitivity may be more fundamental to the human brain than is speech perception. (nymetroparents.com)
The question of whether the environment can physically modify the brain has intrigued scientists from the XVII century until the present day. (psicothema.com)
Scientists are still piecing together the puzzle of how the brain works. (mightynatural.com)

Processing musical pulses recruits motor centers in the brain, supporting the idea that music and movement are closely intertwined. (nymetroparents.com)

No differences in asymmetry were found between emotions in the central and parietal regions. (virginia.edu)

The VEPs, consisting of initial positive-late negative waves, were recorded mainly on the occipital region contralateral to stimulated visual fields. (medscape.com)
The patients had hemiplegia due to a stroke, traumatic brain injury , cerebral palsy, or encephalitis, manifesting mainly as spasticity and weakness in the upper extremity contralateral to the cerebral lesion. (medscape.com)
MRI showed isolated injury to the brain hemisphere contralateral to the paralyzed hand. (medscape.com)

When musicians listen to music, their brains show more active and brilliant illumination than do the brains of non-musicians. (nymetroparents.com)

The difference between heat exhaustion and heat stroke is there is no sweating with heat stroke. (cdc.gov)

Among other physiological differences, musicians who begin training around 7 years of age have a significantly larger corpus callosum, which integrates motor, sensory, and cognitive performance between the right and left lobe of the cerebral cortex, so that messages are able to travel more quickly between these regions. (nymetroparents.com)
Se analizó en los animales el metabolismo oxidativo cerebral del hipocampo (areas CA1, CA3 y giro dentado) mediante histoquímica para la citocromo c oxidasa (CO). Los resultados muestran un incremento significativo de la actividad CO en todas las regiones estudiadas en el grupo aislado, con diferencias entre las areas hipocampales en ambos grupos. (psicothema.com)
Approach-withdrawal and cerebral asymmetry: emotional expression and brain physiology. (virginia.edu)

Until recently, technological limitations prevented a genome-wide appraisal of isoform influence on cell identity in various parts of the brain. (biorxiv.org)

Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells, anabolic steroids effects on pancreas. (swacift.org)
2010). Airborne vapor diffuses to the air:tissue interface and, if may contribute to the human-rat differences in diacetyl-induced soluble, enters the tissue phase. (cdc.gov)

The researchers also found brain signatures that were unique to individual conditions. (neurosciencenews.com)
and psoriatic arthritis may appear the same, symptomatically speaking, but they are two unique conditions with differences in their symptoms, causes, and treatments. (belmarrahealth.com)

However, how the brain contributes to sex-based differences in vasopressin and oxytocin release is poorly understood. (bvsalud.org)
The cerebellum is one brain structure that contributes to brain reserve. (bigthink.com)

Choosing among rewarding options requires coordination of multiple brain functions spanning sensory perception to valuation and motor output. (nature.com)

Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network. (cdc.gov)

Vasopressin is involved in sex-based differences in social behavior and body fluid regulation. (bvsalud.org)
Finally, the brain which is already out of order will give wrong and disordered instruct to its body. (ubc.ca)
These glands are activated when a portion of the brain determines that the body needs to be cooled down. (cdc.gov)

Disgust was found to be associated with right-sided activation in the frontal and anterior temporal regions compared with the happy condition. (virginia.edu)
Happiness was accompanied by left-sided activation in the anterior temporal region compared with disgust. (virginia.edu)

Recent evidence suggests that multisensory integration at the physiological level involves both linear and nonlinear computations. (wakehealth.edu)

Brain reserve refers to the brain structures that provide resilience against neurodegenerative diseases. (bigthink.com)

Anatomy36

Organisms8

Diseases25

Chemicals and Drugs20

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Psychiatry and Psychology12

Phenomena and Processes27

Disciplines and Occupations2

Humanities1

Information Science9

Health Care3

Anatomical7

Functional12

FMRI7

Individual differences6

Mechanisms7

Neural7

Structural12

Individual's1

Cognition2

Neurons9

Role of biological sex2

Connectivity3

Disorders9

Abnormalities1

Behavioral4

Tasks4

Humans2

Scans4

Findings5

Posterior cingul1

Distinct3

Respiration1

Neurodegenerative disease1

Activity15

Signals4

Broader1

Magnitude2

Cortical regions1

Emotion2

Prefrontal cortex1

Patterns4

Neuron2

Occur1

Proteins2

Results7

RESEARCH13

Species1

Function7

Principles2

Gene expression2

PNAS1

Dramatic1

Significant3

Analyze2

Alzheimer's3

Scientists3

Centers1

Parietal1

Contralateral3

Show1

Stroke1

Cerebral3

Identity1

Tissue2

Conditions2

Contributes2

Sensory1

Mutation1

Body3

Anterior2

Suggests1

Resilience1