• These reductions in flow and metabolism were partly attenuated by adjunct N2O. (silverchair.com)
  • A variety of imaging modalities, including structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET) studies of cerebral metabolism, have shown characteristic changes in the brain of patients with Alzheimer disease in prodromal and even presymptomatic states. (medscape.com)
  • there is exquisite coupling of blood flow and metabolism on a regional basis. (neuro-anesthesia.org)
  • Regional flow and metabolism coupling depends on the buildup of metabolites that cause local dilatation of the microvessels. (neuro-anesthesia.org)
  • Other agents that may mediate flow and metabolism coupling include nitric oxide (NO), calcium, adenosine, and eicosanoids such as thromboxane and prostaglandin. (neuro-anesthesia.org)
  • Fig. Schematic depicting gold-standard measurement of cerebral metabolism. (ubc.ca)
  • In collaboration with medical doctors I am now studying the effect of therapies such as controlled hypothermia on cerebral metabolism to establish NIRS as a potential tool to guide and optimize individual care, and, in collaboration with ISS Inc., I have developed a commercial version of our FDNIRS-DCS device. (harvard.edu)
  • Invasive monitoring of cerebral metabolism and intracranial pressure is to be applied in patients with impaired consciousness in order to detect a threatening cerebral ischemia as early as possible. (csnn.eu)
  • 5 , 6 MR susceptometry uses gradient-echo phase maps to estimate oxygen saturation in segments of the jugular and gray matter veins. (ajnr.org)
  • 7 , 8 Susceptibility-weighted imaging is a type of MR susceptometry that can obtain measurements of venous oxygen saturation by using the phase difference between the venous blood and surrounding tissue. (ajnr.org)
  • The effects of protective lung ventilation on regional cerebral oxygen saturation in intracranial tumor operation during dura opening:study protocol for a randomized controlled trial. (researchsquare.com)
  • Objective: To investigate the effects of protective lung ventilation on regional cerebral oxygen saturation during dura opening, that is from Ta (after dura opening) to Tb (before dura closing), in patients undergoing intracranial tumor surgery. (researchsquare.com)
  • Regional cerebral oxygen saturation (rSO2), partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2), oxygenation index (OI), lactic acid level (Lac) in arterial blood, and mean arterial pressure (MAP) will be compared before anesthesia (T0), before dura opening (T1), after dura closing (T2) and 24 h after surgery (T3). (researchsquare.com)
  • Discussion: This study aims to determine whether protective lung ventilation during dura opening can improve regional cerebral oxygen saturation and the state of pulmonary ventilation in patients undergoing intracranial tumor surgery, and to investigate whether this strategy does not affect the degree of brain tissue swelling and the reoperation rate after operation. (researchsquare.com)
  • Results indicate differences in variability of oscillations of oxygen saturation (SO 2 ) between the two different bands. (frontiersin.org)
  • Near-infrared spectroscopy (NIRS) is a noninvasive, continuous method of measuring regional tissue oxygen saturation, and may be used to supplement conventional monitoring to improve neonatal perioperative care. (nih.gov)
  • Neonates were monitored with both cerebral and renal NIRS for 24 h after induction of anesthesia and compared with systemic blood pressure (BP), peripheral oxygen saturation (SpO2 ), and heart rate (HR). (nih.gov)
  • A near-infrared spectroscopy sensor connected to a regional oximetry system (O3 TM , Masimo, Irvine, CA) was placed on the subject's forehead, to provide continuous measurement of regional oxygen saturation (rSO 2 ). (lww.com)
  • Absolute and trend accuracy of the regional oximetry system was determined by comparing rSO 2 against reference cerebral oxygen saturation (SavO 2 ), that is calculated by combining arterial and venous saturations of oxygen in the blood samples. (lww.com)
  • However, standard monitoring methods of systemic arterial and venous oxygen saturation may not represent the oxygenation state in peripheral tissues such as the brain. (lww.com)
  • In recent years, the measurement of cerebral regional oxygen saturation (rSO 2 ) during resuscitation has attracted attention. (biomedcentral.com)
  • In recent years, the measurement of cerebral regional oxygen saturation (rSO 2 ) by near-infrared spectroscopy (NIRS) during resuscitation has attracted attention. (biomedcentral.com)
  • Electrocardiogram (ECG), peripheral oxygen saturation (SpO 2 ), noninvasive blood pressure monitoring were performed on the patients. (clinmedjournals.org)
  • Again, NIRS probes were placed right and left on the forehead for right cerebral oxygen saturation follow-up (INVOS 5100C oximeter, Coivden 2-channel right-left). (clinmedjournals.org)
  • Traditional patient monitoring may not detect cerebral tissue hypoxia, and typical interventions may not improve tissue oxygenation. (lww.com)
  • 1 , 2 Brain tissue is particularly susceptible to hypoxia, and oxygenation of the cerebral tissue has been found to be an important predictor of short- and long-term clinical outcomes. (lww.com)
  • 7 Therefore, maintenance of adequate cerebral oxygenation may increase patient safety by preventing decreased cerebral perfusion and prolonged cerebral tissue ischemia. (lww.com)
  • Fast, low-angle shoot functional magnetic resonance imaging (fMRI), based on the blood oxygenation level-dependent (BOLD) effect, was combined with optical recording of intrinsic signals (ORIS) and 2-deoxyglucose labeling in gerbil barrel cortex. (jneurosci.org)
  • Thus, we evaluated the effect of RIPC on regional cerebral oxygenation after tourniquet release during TKR. (medsci.org)
  • Regional cerebral oxygenation and pulmonary oxygenation were assessed up to 24 h postoperatively. (medsci.org)
  • RIPC increased cerebral oxygenation after tourniquet release during TKR by improving pulmonary oxygenation. (medsci.org)
  • Microcirculation facilitates tissue oxygenation and the exchange of substances between tissues and blood. (springeropen.com)
  • As an experimentalist interested in biomedical applications, I have tested the technique for several medical applications, including detection of breast cancer, assessment of peripheral vascular disease, non-invasive blood glucose monitoring, brain oxygenation monitoring, brain functional activity, and neurovascular coupling investigation. (harvard.edu)
  • Since early 2000, I have devoted part of my time to the development of a sophisticated near-infrared spectroscopy device (FDNIRS-DCS) that can determine brain health in infants at the bedside by quantifying regional hemoglobin oxygenation, cerebral blood volume, cerebral blood flow, and oxygen consumption in the neonates brain. (harvard.edu)
  • We evaluated anesthesia depth, cerebral oxygenation and postoperative cognitive functions with NIRS and BIS monitoring and Mini-Mental State Examination (MMSE) score. (clinmedjournals.org)
  • Perfusion and oxygenation, in turn, depend on the heart's ability to pump oxygenated blood throughout the body. (medscape.com)
  • NIRS reported cerebral/renal hypoxia 2.8 (±8.3)%/19.3 (±25.4)% of the time intraoperatively and 9.6 (±17.0)%/9.9 (±18.9)% of the time postoperatively. (nih.gov)
  • The high incidences of regional hypoxia reported by NIRS in this study imply that there is a need for a more specific regional cerebral and renal monitoring. (nih.gov)
  • Masimo O3 regional oximetry provided absolute root-mean-squared error of 4% and relative root-mean-squared error of 2.1% in healthy volunteers undergoing controlled hypoxia. (lww.com)
  • Cerebral hypoxia could be linked to neurological complications, 3 organ dysfunctions, 4 , 5 stroke, 6 and increased hospital length of stay. (lww.com)
  • Acute hypoxia impairs posterior cerebral bioenergetics and memory in man. (waseda.jp)
  • We sought to examine the effects of acute hypoxia on central executive (selective attention and response inhibition) and non-executive (memory) performance and the extent to which impairments are potentially related to reductions in regional cerebral blood flow and oxygen delivery. (waseda.jp)
  • Cerebral hypoxia was monitored using NIRS monitoring in patients who underwent controlled hypotension with total intravenous anesthesia (TIVA) or balanced general anesthesia, and the effect of anesthesia methods on postoperative cognitive function change was investigated. (clinmedjournals.org)
  • Neonatal hypoxia/ischemia is a known cause of cerebral damage resulting from inadequate blood flow and/or oxygen delivery to the infant brain before, during, or after birth. (sbir.gov)
  • The authors quantified the effects of sevoflurane and propofol as sole anesthetics and in combination with N2O on regional cerebral blood flow (rCBF), metabolic rate of oxygen (rCMRO2), and blood volume (rCBV) in the living human brain using positron emission tomography. (silverchair.com)
  • Regional cerebral blood flow measured during symptom provocation in obsessive - compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. (colongquanhiep.vn)
  • 3 The causes of strokes can be divided into two basic groups: (1) obstruction of the blood vessels leading to ischemia, and (2) rupture of blood vessel walls leading to hemorrhage. (vin.com)
  • Moreover, the long period of brain operation is more likely to cause the imbalance of brain oxygen supply and consumption. (researchsquare.com)
  • The unbalance of brain oxygen supply and consumption may lead to deterioration of brain function, such as postoperative cognitive function[6]. (researchsquare.com)
  • Arai T, Mori K, Nakao S, Watanabe K, Kito K, Aoki M, Mori H, Morikawa S, Inubushi T (1991) In vivo oxygen-17 nuclear magnetic resonance for the estimation of cerebral blood flow and oxygen consumption. (springer.com)
  • The exceptionally high demand for circulating blood and oxygen is reflected is reflected in the disproportionately high rate of CBF compared with flow to other parts of the body, comprising 20% of the cardiac output and 15% of oxygen consumption when the body is at rest, even though the brain makes up only 2% of the body weight. (vin.com)
  • To examine the effects of phenylephrine infusion and increases in pump flow on systemic oxygen supply and demand, when they are used to support mean arterial pressure (MAP) during normothermic cardiopulmonary bypass (CPB), we measured oxygen delivery (DO 2 ), oxygen consumption (VO 2 ) and lactate concentration in patients with good left ventricular function undergoing elective CABG. (czytelniamedyczna.pl)
  • Oxygen consumption increased when mean blood pressure decreased below 50 mm Hg (6.67 kPa). (czytelniamedyczna.pl)
  • With the advances of magnetic resonance technology, the CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen can be measured in MRI. (ajnr.org)
  • Our aim was to measure the CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen use in patients with different severities of middle cerebral artery stenosis or acute stroke by using the arterial spin-labeling and susceptibility-weighted imaging techniques. (ajnr.org)
  • Arterial spin-labeling and SWI sequences were used to acquire CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen. (ajnr.org)
  • Hemispheres with occluded MCA (group 3) or acute stroke (group 4) had a significantly lower CBF and cerebral metabolic rate of oxygen and a significantly higher oxygen extraction fraction than the contralateral hemisphere. (ajnr.org)
  • When this offset a decrease in CBF, the cerebral metabolic rate of oxygen remained at a normal level. (ajnr.org)
  • An occluded MCA led to reduction in both the CBF and cerebral metabolic rate of oxygen. (ajnr.org)
  • Moreover, the oxygen extraction fraction and cerebral metabolic rate of oxygen significantly increased and decreased, respectively, in the occluded MCA region during acute stroke. (ajnr.org)
  • It is possible to use both parameters and the arterial oxygen content to derive cerebral metabolic rate of oxygen (CMRO 2 ) use, which is of critical importance in the occurrence of stroke. (ajnr.org)
  • Tetralogy of Fallot patients with pulmonary atresia (TOF/PA) present a pulmonary blood supply directly from aortic collateral arteries. (stanford.edu)
  • In a pathologic state, PH of all forms leads to an increase in resistance to flow across the pulmonary vascular bed. (medscape.com)
  • 14 mmol/L, hyperbilirubinaemia in the several undesirable consequences, includ- level of exchange transfusion [ 3 ], bleeding ing haemodynamic, pulmonary, cerebral, tendency, evidence of necrotizing entero- renal and gastrointestinal disturbances [ 3 ]. (who.int)
  • Other maternal conditions such as aortic stenosis, pulmonary hypertension, or right-to-left shunts are also relative contraindications to the use of regional analgesia. (medscape.com)
  • The ratio between cerebral blood flow and cerebral blood volume can be an accurate predictor of decreased cerebral perfusion pressure, thereby predicting cerebral circulation. (wikipedia.org)
  • Autoregulation allows CBF to remain constant if the cerebral perfusion pressure (CPP) varies between 50 and 150 mm Hg. (neuro-anesthesia.org)
  • As with other intravenous induction agents, reduction in cerebral oxygen utilization is roughly proportional to the reduction in cerebral blood flow. (nih.gov)
  • Arai T, Nakao S, Mori K, Ishimori K, Morishima I, Miyazawa T, Fritz-Zieroth B (1990) Cerebral oxygen utilization analyzed by the use of oxygen-17 and its nuclear magnetic resonance. (springer.com)
  • S+N especially reduced the oxygen extraction fraction, suggesting disturbed flow-activity coupling in humans at a moderate depth of anesthesia. (silverchair.com)
  • Possible regional anesthesia techniques include epidural analgesia, spinal analgesia (sometimes referred to as the intrathecal or subarachnoid space), or a combination of epidural and spinal analgesia. (medscape.com)
  • As exacerbation of neurological diseases might be attributed without cause to the anesthetic agent, many clinicians avoid regional anesthesia in its presence. (medscape.com)
  • Retinal changes may, therefore, associate with CBF in critically ill patients, offering a novel biomarker to monitor in real-time and reduce cerebral hypoperfusion. (springeropen.com)
  • Neurological complications and postoperative cognitive dysfunction (POCD) may occur as a result of developing cerebral hypoperfusion [ 2 ]. (clinmedjournals.org)
  • Carbon monoxide administered by a single inhalation is a reliable and accurate blood tracer for measuring cerebral blood volume with emission computed tomography. (wikipedia.org)
  • Relationship between cerebral blood flow and arterial carbon dioxide tension (PaCO 2 ) in the normocapnic adult, the hypercapnic adult, and the newborn. (neuro-anesthesia.org)
  • Reference blood samples were taken from the radial artery and internal jugular bulb vein, at baseline and after a series of increasingly hypoxic states induced by altering the inspired oxygen concentration while maintaining normocapnic arterial carbon dioxide pressure (PaCO 2 ). (lww.com)
  • My interest (and thesis) is in the regulation of cerebral blood flow, particularly in the context of this regulation by changes in arterial blood gases (oxygen and carbon dioxide). (ubc.ca)
  • 1988. Neurological examination, computerized- tomography, cerebral blood-flow and neuropsychological examination in workers with long-term exposure to carbon disulfide. (cdc.gov)
  • 1992. Regional cerebral blood flow after long-term exposure to carbon disulfide. (cdc.gov)
  • Cerebral hemodynamics reflect cognitive processes and underlying physiological processes, both of which are captured by functional near infrared spectroscopy (fNIRS). (frontiersin.org)
  • A reduction in cerebral blood flow in brain tissue is typically accompanied by a compensatory increase in the oxygen extraction fraction (OEF) to maintain normal neuronal function. (ajnr.org)
  • Ischemic stroke will cause a substantial reduction in cerebral blood volume. (wikipedia.org)
  • This reduction in blood flow appears to be uniform in the absence of intracranial space occupying lesions. (nih.gov)
  • Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)
  • These magnetic resonance cerebral blood volume imaging methods can be applied to academic research of normal human brain activities and clinical studies of patients with brain tumors. (wikipedia.org)
  • MRI is contraindicated in patients with pacemakers , certain metal prostheses (eg, cochlear implants ), or a large number of cerebral aneurysm clips. (medscape.com)
  • However, clinical data indicates that etomidate administration in geriatric patients, particularly those with hypertension, may result in decreases in heart rate, cardiac index, and mean arterial blood pressure. (nih.gov)
  • Among patients with AD, the presence of ketone bodies in the body can improve cerebral circulation. (karger.com)
  • Blood-brain barrier (BBB) impairment is a stable characteristic over 1 year and is present in an important subgroup of patients with Alzheimer disease. (medscape.com)
  • We measured the serial changes in the cerebral rSO 2 values of patients with out-of-hospital cardiac arrest before and after ECPR in Osaka National Hospital. (biomedcentral.com)
  • From January 2013 through March 2015, the serial changes in the cerebral rSO 2 values were evaluated in 16 patients. (biomedcentral.com)
  • Our study suggested that the patients whose cerebral rSO 2 values showed no significant improvement after ECPR might have had a good neurological prognosis. (biomedcentral.com)
  • By chance, we detected a difference in the way the values of cerebral rSO 2 in patients with OHCA changed before and after the application of ECPR. (biomedcentral.com)
  • Monitoring microcirculatory flow offers the potential to enhance monitoring in the care of critically ill patients, and imaging retinal blood flow during critical illness offers a potential biomarker for cerebral microcirculatory perfusion. (springeropen.com)
  • Cerebral vasospasms are among the most severe complications, identified in 40-70% of patients after subarachnoid bleeding. (csnn.eu)
  • We compared laboratory tests, age, education status, blood loss, and fluid input between POCD and non-POCD patients. (biomedcentral.com)
  • In obstetric patients, regional analgesia refers to partial or complete loss of pain sensation below the T8 to T10 spinal level. (medscape.com)
  • It also helps control blood pressure in women with preeclampsia by alleviating labor pain, and it blunts the hemodynamic effects of uterine contractions and the associated pain response in patients with other medical complications. (medscape.com)
  • After a large dose of iodinated contrast agent was injected into the brain tissue, the temporal change in iodine concentration was compared to changes in cerebral arterial input. (wikipedia.org)
  • The objective of this study was to clarify the relationship between the serial changes in the cerebral rSO 2 values during extracorporeal cardiopulmonary resuscitation (ECPR) and the neurological outcome. (biomedcentral.com)
  • The serial changes in the cerebral rSO 2 values during ECPR may predict a patient's neurological outcome. (biomedcentral.com)
  • Medically speaking a wide range of neurological and psychological disorders affects various cerebral structures. (healthanalyzermachine.com)
  • The transportation of these fuel molecules requires sufficient blood flow through a cerebral vasculature with adequate capacity. (vin.com)
  • Autoregulatory curve of the cerebral vasculature in the normotensive adult, the hypertensive adult, and the newborn. (neuro-anesthesia.org)
  • This review discusses the relationship between cerebral and retinal blood flow, and the relevance of that relationship to systemic pathology and monitoring microcirculatory perfusion in critical illness, focussing more on sepsis. (springeropen.com)
  • Preoperative and postoperative arterial blood gas (ABG), S-100β, C-reactive protein (CRP), and cognitive dysfunction scales were tested. (biomedcentral.com)
  • Chest compression alone could not increase the cerebral rSO 2 value, which was found to gradually increase with a return of spontaneous circulation (ROSC). (biomedcentral.com)
  • During CPB with low mean pressure, both increased pump flow and phenylephrine infusion can maintain satisfactory oxygen delivery and peripheral circulation. (czytelniamedyczna.pl)
  • Helps control lipid levels and lower oxidised LDL (bad cholesterol) and maintain heart health by regulating blood circulation in the body. (arelang.com)
  • These findings provide preliminary evidence for the utility of the OV index and are the first to describe the relationship between cerebral autoregulation and age in children using fNIRS methodology. (frontiersin.org)
  • In particular, these variations provide information about cerebral autoregulation (CA), the mechanism that optimizes oxygen delivery to the brain. (frontiersin.org)
  • Cerebral blood flow (CBF) is reduced and autoregulation impaired in sepsis, but current methods to image CBF do not reproducibly assess the microcirculation. (springeropen.com)
  • 7 , 8 This technique requires blood vessels to have a substantially greater length than the diameter. (ajnr.org)
  • With the growing recognition of the complexity of neurovascular coupling, research has focused on the "neurovascular unit", a close association between neurons, astrocytes and blood vessels. (springer.com)
  • 5 Any diseases which affect the cerebral blood vessels will cause disturbances of the cerebral blood flow (CBF) which in turn can lead to tissue damage. (vin.com)
  • In isolated vessels, when the vessel wall is stretched, as it would be by increased blood pressure, the smooth muscle contracts, causing a vasoconstriction that reduces flow. (neuro-anesthesia.org)
  • Grafts, sometimes made of artificial materials, may be implanted to replace blood vessels or connective tissue, and metal rods may be inserted into bone to stabilize or replace broken parts. (msdmanuals.com)
  • The cerebral blood volume maps can be calculated by dynamic magnetic resonance image set obtained by echo planar imaging after intravenous injection of thiol contrast agent. (wikipedia.org)
  • Cerebral blood volume measurements are based on methods used in dynamic computed tomography. (wikipedia.org)
  • Assessment and maintenance of end-organ perfusion are key to resuscitation in critical illness, although there are limited direct methods or proxy measures to assess cerebral perfusion. (springeropen.com)
  • The ICP elevation along with pneumoperitoneum further increases in the extreme Trendelenburg positioning, which may rise the risk of brain edema, blood-brain barrier damage, as well as potential brain injury caused by the decrease of cerebral perfusion and insufficient supply of oxygen. (biomedcentral.com)
  • There was no reopening after the ductal closure during the hospital stay or in the follow-up visits in either group and no excessive increases in the blood urea nitrogen or serum creatinine levels were observed. (who.int)
  • Etomidate induction is associated with a transient 20% to 30% decrease in cerebral blood flow. (nih.gov)
  • We think that, the desflurane group be preferred as a priority with less remifentanil expenditure, lower blood pressure values, higher rSO 2 values, no 20% decrease in rSO 2 values, faster extubation, and statistically significant early recovery. (clinmedjournals.org)
  • A small decrease in the vessel diameters may lead to a remarkable decrease of the blood flow. (biomedcentral.com)
  • About 15% of the blood volume is present in the arteries, 40% in the veins, and 45% in the nerve tissue and capillaries. (wikipedia.org)
  • In the dog, blood supply to the brain arises from the basilar and internal carotid arteries, which join at the base to form the arterial circle of Willis. (vin.com)
  • 5 The cerebrum is supplied by three pairs of cerebral arteries arising from this arterial circle, with each one responsible for the perfusion of large but overlapping areas of the cerebrum. (vin.com)
  • It would be therefore be interesting enough to study regional CBF (using Duplex ultrasound of the internal carotid and vertebral arteries, see Figure) during a prolonged apnea, but our plan goes further. (ubc.ca)
  • In still other procedures, arteries and veins are attached in new places to provide additional blood flow to areas that do not receive enough. (msdmanuals.com)
  • In the state of ketosis, blood glucose levels are stable, reaching physiological values. (karger.com)
  • The central nervous system (CNS) requires a continuous supply of glucose and oxygen to sustain its high expenditure of energy. (vin.com)
  • Numerous studies are under way to identify specific imaging markers for different types of dementia, including cerebral volumetric measurements, diffusion imaging, spectroscopy, very-high-field MRI scans of senile plaques, and PET scan markers of senile plaques. (medscape.com)
  • Regional citrate anticoagulation (RCA) is rarely preferred in neonates because of citrate accumulation (CA) and metabolic complications. (bvsalud.org)
  • Ischaemic reperfusion injury (IRI) after tourniquet release during total knee arthroplasty (TKR) is related to postoperative cerebral complications. (medsci.org)
  • As a result, transient hypotension and acidosis can occur [ 4 , 5 ], and serious cerebral complications can be induced [ 3 , 6 , 7 ]. (medsci.org)
  • The aim of this prospective observational study was to find the incidence rate as well as possible risk factors of POCD in RARC with cerebral oxygen monitoring. (biomedcentral.com)
  • Unlike traditional pulse oximeters, regional oximeters measure a mix of arterial, capillary, and venous blood in cerebral and peripheral tissue and do not depend on pulsatile flow. (lww.com)
  • This treatment is used to hasten tissue recovery and improve its physiological aspects, by providing an increased supply of oxygen to the damaged tissue. (mdpi.com)
  • Ketosis is indicated by reaching a blood BOHB concentration of ≥0.5 mmol/L. Ketone bodies are used in tissues, serving as their main energy substrate. (karger.com)
  • A clear tomographic depiction of cerebral blood volume distribution in human subjects can achieve by using emission computed tomography, which provides real-time measurements of the cerebral hemodynamic parameters. (wikipedia.org)
  • Measurements of heart rate (HR), mean arterial pressure (MAP), central venous pressure (CVP), end-tidal CO 2 (etCO 2 ), and cerebral oxygen were immediately obtained after different time points during the surgery. (biomedcentral.com)
  • 3.Reddan JM, Macpherson H, White DJ, Scholey A, Pipingas A. Examining the relationship between nutrition and cerebral structural integrity in older adults without dementia. (edu.au)
  • Our study demonstrated that the CBF SPECT-CA method can detect the brain blood perfusion changes induced by rehabilitation with high sensitivity and accuracy. (biomedcentral.com)
  • the impairment may be global or regional. (vin.com)