Regional cerebral cerebral arterial diseases. Medical search. Frequent questions

G-protein-coupled receptors and ion channels present on the endothelial cells and vascular smooth muscle cells (SMCs) that form the walls of cerebral blood vessels initiate many of the signaling cascades that enable these intrinsic adaptive processes. (elifesciences.org)
We hypothesized that bradykinin receptor inhibition alleviates the vascular dysfunction in a transgenic arcAβ mouse model of cerebral amyloidosis and that fMRI techniques can be used to monitor the treatment response. (uzh.ch)
Similarly, measuring cerebral blood volume changes upon pharmacological stimulation using vessel dilator acetazolamide revealed recovery of regional impairment of cerebral vascular reactivity in arcAβ mice upon noscapine treatment. (uzh.ch)
In summary, bradykinin receptors blockade recovered cerebral vascular dysfunction in a mouse model of cerebral amyloidosis. (uzh.ch)
Cerebral vascular insufficiency, typically caused by extracranial or intracranial steno-occlusive disease (any arterial occlusion or severe extracranial or intracranial stenosis in symptomatic arterial territory), is the leading cause of ischemic stroke . (medscape.com)
1 2 Arteriolosclerosis (age-related or vascular risk-factor-related small vessel diseases) is sporadic and the most prevalent form of CSVD. (bmj.com)
He has also studied the role of cerebral micro-emboli in degenerative and vascular dementias and developed methods to quantify dysfunction of cerebro-vascular autoregulation. (beardsandjackson.com)
His group has an international reputation in the development of biomarkers of the vascular microenvironment in tumours and in microvascular brain disease. (beardsandjackson.com)
Cerebral vascular pathology comprises the major part of neurology and neurosurgery. (hindawi.com)
Finally, the authors outline the methodologies behind specific perfusion magnetic resonance imaging (MRI) and ultrasound Doppler techniques, which allow measurement of disease-specific and age-specific vascular changes in the aging population and MS patients. (ccsvi.nl)
After normal trial balloon occlusion (TBO) and flow testing results, permanent balloon occlusion is a preoperative intervention that may reduce cerebral vascular accident (CVA) incidence over simple ligation in this clinical setting. (medscape.com)
During a prolonged apnea, arterial content of O 2 decreases and CO 2 increases - each of which drive vascular dilation in the brain and a consequent increase in CBF. (ubc.ca)
Much of our work has focused on cardiovascular function and specifically how blood pressure, arterial stiffness and vascular elasticity contribute to cognitive function and the risk of cognitive decline. (edu.au)
Characterization of cerebral microangiopathy using 3 Tesla MRI: Correlation with neurological impairment and vascular risk factors. (mpg.de)
In August 2020, Koniklijke Philips NV announced the acquisition of Intact Vascular Inc. to expand the portfolio of minimally invasive therapy options for peripheral artery disease. (reportsanddata.com)
Magnetic resonance angiography segment is expected to account for largest revenue share over the forecast period owing to increasing use of this technique for identifying vascular anomalies such as cerebral aneurysms, arterial lesions in sickle cell disease, arterial ischemic infarction, and other vascular anomalies. (reportsanddata.com)
Diabetes is serious due to its complications, namely: cardiovascular ailments, cerebral vascular accidents, renal insufficiency, blindness, sexual impotence and gangrene of the feet leading to amputation. (who.int)

Intracranial hematoma and Intracerebral hemorrhage (ICH) will cause an increase in cerebral blood volume. (wikipedia.org)
Both cerebral blood volume and cerebral blood flow depend on several important parameters, including cerebrovascular resistance, intracranial pressure, and mean arterial pressure. (wikipedia.org)
In a systematic review of effects of revascularization on cognitive outcomes in patients with intracranial steno-occlusive disease, review authors examined existing literature on intracranial steno-occlusive disease, including intracranial atherosclerosis and MMD, to determine the extent and quality of evidence for the effect of revascularization on cognitive performance. (medscape.com)
They concluded that effects of revascularization on cognitive performance in intracranial steno-occlusive disease remain uncertain due to limitations in existing studies. (medscape.com)
It was shown that cerebral revascularization using extracranial to intracranial bypass may result in neurological symptoms improvement and an objective increase in regional cerebral blood flow in a selective cohort of patients with symptomatic chronic cerebrovascular ischemia [ 1 ]. (hindawi.com)
24. Development of Brain Infarction after Extracranial-Intracranial Bypass Surgery in a Patient with Moyamoya Disease. (yumc.ac.kr)
This includes the establishment of a new rat model of chronic intracranial venous hypertension and its effects on CBF and behaviour (together with the Institute for neurosurgical pathophysiology, University of Mainz), as well as intraoperative assessment of CBF-regulation during resection of cerebral arteriovenous malformations and in temporomesial epilepsy. (unige.ch)
Noninvasive imaging of asymptomatic brain aneurysms, arteriovenous malformations, and intracranial arterial stenosis became available. (hindawi.com)
Flow velocity and pulsatility index were measured in the middle cerebral, basilar and intracranial internal carotid arteries of a sample of 141 diabetic patients with no other risk factors, and 132 age- and sex-matched healthy controls. (who.int)

Ischemic stroke will cause a substantial reduction in cerebral blood volume. (wikipedia.org)
Cerebral blood volume is one of the parameters that is assessed with CT perfusion, often as part of Ischemic stroke evaluation. (wikipedia.org)
In its mildest form, impaired regional CBF causes a transient ischemic attack (TIA). (vin.com)
We hypothesized that TRPA1 channels in endothelial cells are activated by hypoxia-derived reactive oxygen species, leading to cerebral artery dilation and reduced ischemic damage. (elifesciences.org)
Each of these conditions puts the brain at risk of cerebral ischemia or ischemic stroke. (medscape.com)

However, cerebral small vessel disease (CSVD) accounts for about 50%-70% of VCI, which represented a more homogeneous subtype of VCI. (bmj.com)
The term cerebral small vessel disease (CSVD) encompasses all the pathological processes that affect the small vessels of the brain, including small arteries and arterioles, and capillaries and small veins. (bmj.com)
Small vessel disease- what's the big deal? (apsc2023hk.org)
Characterization of cerebral small vessel disease by proton spectroscopy and morphological magnetic resonance. (mpg.de)
This study assessed its validity in determining cerebral small vessel disease in patients with type 2 diabetes mellitus. (who.int)
Transcranial doppler may be useful in early diagnosis of cerebral small vessel disease in patients with type 2 diabetes mellitus. (who.int)

In the dog, blood supply to the brain arises from the basilar and internal carotid arteries, which join at the base to form the arterial circle of Willis. (vin.com)
5 The cerebrum is supplied by three pairs of cerebral arteries arising from this arterial circle, with each one responsible for the perfusion of large but overlapping areas of the cerebrum. (vin.com)
Using isolated cerebral arteries expressing a Ca 2+ biosensor in endothelial cells, we show that 4-hydroxynonenal and hypoxia increased TRPA1 activity, detected as TRPA1 sparklets. (elifesciences.org)
Hypoxia caused dilation of cerebral arteries, which was disrupted by antioxidants, TRPA1 blockade and by endothelial cell-specific Trpa1 deletion ( Trpa1 ecKO mice). (elifesciences.org)
Such conditions include moyamoya disease , carotid artery disease , and atherosclerosis of the cerebral arteries. (medscape.com)
Microvascular anastomosis techniques are important for revascularization surgeries on brachiocephalic and carotid arteries and complex cerebral aneurysms and even during resection of brain tumors that obstruct major cerebral arteries. (hindawi.com)
It would be therefore be interesting enough to study regional CBF (using Duplex ultrasound of the internal carotid and vertebral arteries, see Figure) during a prolonged apnea, but our plan goes further. (ubc.ca)
TCD enables continuous monitoring of mean blood flow velocity through the cerebral arteries and therefore the evaluation of cerebral blood flow [ 2 ]. (hindawi.com)

arterial infarction can be due to either obstruction from thrombosis or embolism or to occlusion from blood vessel abnormalities such as vasculitis. (vin.com)
Although the bones of the scull remain an obstacle for ultrasound waves and therefore ultrasound may not seem to be the optimal technique for cerebral vessel imaging, transcranial ultrasound techniques were improved and found their place and indications. (hindawi.com)
The latter technique can both quantify regional brain metabolism/activity, and haemopoietic tissue activity and large vessel arterial inflammation [6,8]. (pace-cme.org)

Bypass techniques are still valuable for the surgical treatment of complex cerebral aneurysms by reducing the risk of temporary and constant brain ischemia due to the alteration in blood flow. (hindawi.com)

Cerebral hypoxia-ischemia remains a not infrequent complication in children with congenital heart disease (CHD) before, during and after cardiothoracic interventions. (nonin.com)
The Nonin EQUANOX Regional Oximeter System with EQUANOX Advance 8004CB sensor accurately measures the absolute value of cerebral saturation in children over a wide range of oxygenation levels, and may offer advantages in the detection of tissue hypoxia-ischemia in CHD over other devices. (nonin.com)
Hypoxia and ischemia are linked to oxidative stress, which can activate the oxidant-sensitive transient receptor potential ankyrin 1 (TRPA1) channel in cerebral artery endothelial cells, leading to vasodilation. (elifesciences.org)
15. Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in rats. (yumc.ac.kr)

Cerebral autoregulation maintains constant blood flow (CBF) through the brain in spite of changing mean arterial pressure [ 8 ]. (hindawi.com)
Autoregulation of cerebral blood flow consists of mechano- and chemoregulation. (hindawi.com)
Illustration of the traditionally viewed concept of cerebral autoregulation (black line) compared to the pressure‐dependent relationship of cerebrovascular control (red line). (comprehensivephysiology.com)

Our aim was to measure the CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen use in patients with different severities of middle cerebral artery stenosis or acute stroke by using the arterial spin-labeling and susceptibility-weighted imaging techniques. (ajnr.org)

It is a new method for studying hemodynamic changes in brain pathophysiology, including clinical studies of cerebrovascular diseases or brain tumors. (wikipedia.org)
Emergence of age-associated pathology, such as cardiovascular diseases, may interact with the MS pathophysiology and further contribute to disease progression. (ccsvi.nl)
This coordinate-based meta-analysis included voxel-based morphometry (VBM) studies and resting-state voxel-based pathophysiology (VBP) studies of blood flow, glucose metabolism, regional homogeneity, and amplitude of low-frequency fluctuations (ALFF) and fractional ALFF (fALFF). (psychiatryonline.org)
Cerebral endothelial dysfunction is mentioned in the pathophysiology of several neurological diseases. (hindawi.com)

However, clinical data indicates that etomidate administration in geriatric patients, particularly those with hypertension, may result in decreases in heart rate, cardiac index, and mean arterial blood pressure. (nih.gov)
Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. (nih.gov)
Chemoregulation is in direct correlation to the serum level of carbon dioxide (CO 2 ) [ 8 ] and is, contrary to mechanoregulation, independent of changes in mean arterial pressure. (hindawi.com)
Comparisons of mean arterial blood pressures in rats (closed circles, solid lines) and humans (open circles, broken lines) during progressive lower body negative pressure (A) and controlled hemorrhage (B). (comprehensivephysiology.com)
Responses of heart rate (broken line) and mean arterial pressure (solid line) during graded LBNP in a single subject demonstrating the onset of severe hypotension and bradycardia with hemodynamic decompensation. (comprehensivephysiology.com)

After a large dose of iodinated contrast agent was injected into the brain tissue, the temporal change in iodine concentration was compared to changes in cerebral arterial input. (wikipedia.org)
Determination of cerebrovascular reactivity by means of fMRI signal changes in cerebral microangiopathy: A correlation with morphological abnormalities. (mpg.de)

The present study aimed to examine the effect of acute HG on cerebral endothelial function as one of the essential cerebral blood flow regulatory functions. (waseda.jp)
These results suggest that enhancement in cerebral endothelial function is not an essential mechanism responsible for acute HG‐induced cognitive improvement. (waseda.jp)
Does handgrip exercise, a small muscle exercise, improve cerebral endothelial function? (waseda.jp)
Acute interval isometric handgrip exercise (2 min of exercise at 25% maximum voluntary contraction, followed by 3 min of recovery, repeated for a total of 4 sets) did not improve cerebral endothelial function. (waseda.jp)
Since the cerebrovascular shear rate did not change during exercise, it is possible that acute handgrip exercise is not sufficient stimulation to improve cerebral endothelial function. (waseda.jp)
In this review, the role of cerebrovascular reactivity to L-arginine (CVR-L-Arg) for assessment of cerebral endothelial function is discussed. (hindawi.com)
However, it seems to show specific cerebral endothelial function. (hindawi.com)
So far CVR-L-Arg has been used to study cerebral endothelial function in many pathological conditions such as stroke, migraine, etc. (hindawi.com)
In conclusion CVR-L-Arg is a promising noninvasive research method that could provide means for evaluation of cerebral endothelial function in physiological and pathological conditions. (hindawi.com)
Endothelial function is not uniform throughout the arterial system. (hindawi.com)
Until recently it was impossible to determine specific cerebral endothelial function. (hindawi.com)
However, these techniques do not enable any evaluation of cerebral endothelial function. (hindawi.com)
In the past few years cerebrovascular reactivity to L-arginine by means of TCD has emerged as a parameter for evaluation of cerebral endothelial function [ 3 - 7 ]. (hindawi.com)

My interest (and thesis) is in the regulation of cerebral blood flow, particularly in the context of this regulation by changes in arterial blood gases (oxygen and carbon dioxide). (ubc.ca)
The role of pericytes in the regulation of cerebral blood flow (CBF) and neurovascular coupling remains, however, under debate. (nature.com)
In the CNS EETs have been shown to be involved in regulation of cerebral blood flow (Iliff et al. (mdm2-inhibitors.com)

Carbon monoxide administered by a single inhalation is a reliable and accurate blood tracer for measuring cerebral blood volume with emission computed tomography. (wikipedia.org)

We identified the numerical order of the Soptimal as the characterizing Alzheimer's disease risk events (CARE) index to measure disease stage. (humanconnectome.org)

Perfusion MRI using an arterial spin labeling technique showed regional hypoperfusion in arcAβ compared to non-transgenic controls, which was alleviated by noscapine treatment. (uzh.ch)

These magnetic resonance cerebral blood volume imaging methods can be applied to academic research of normal human brain activities and clinical studies of patients with brain tumors. (wikipedia.org)

Background and aims The aim of our study is to compare the postnatal cerebral tissue oxygenation values in babies with early versus late cord clamping born after elective C/S. (bmj.com)
Thus, we evaluated the effect of RIPC on regional cerebral oxygenation after tourniquet release during TKR. (medsci.org)
Regional cerebral oxygenation and pulmonary oxygenation were assessed up to 24 h postoperatively. (medsci.org)
RIPC increased cerebral oxygenation after tourniquet release during TKR by improving pulmonary oxygenation. (medsci.org)

Cerebral revascularization is surgery that restores blood flow to the brain, decreasing the chance of stroke or other damage to brain tissue. (medscape.com)
Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? (mcmaster.ca)
Hemispheres with occluded MCA (group 3) or acute stroke (group 4) had a significantly lower CBF and cerebral metabolic rate of oxygen and a significantly higher oxygen extraction fraction than the contralateral hemisphere. (ajnr.org)
Moreover, the oxygen extraction fraction and cerebral metabolic rate of oxygen significantly increased and decreased, respectively, in the occluded MCA region during acute stroke. (ajnr.org)
It is possible to use both parameters and the arterial oxygen content to derive cerebral metabolic rate of oxygen (CMRO 2 ) use, which is of critical importance in the occurrence of stroke. (ajnr.org)

A variety of imaging modalities, including structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET) studies of cerebral metabolism, have shown characteristic changes in the brain of patients with Alzheimer disease in prodromal and even presymptomatic states. (medscape.com)
The intravenous administration of up to 0.6 mg/kg of etomidate to patients with severe cardiovascular disease has little or no effect on myocardial metabolism, cardiac output, peripheral circulation or pulmonary circulation. (nih.gov)
Fig. Schematic depicting gold-standard measurement of cerebral metabolism. (ubc.ca)

Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)
As with other intravenous induction agents, reduction in cerebral oxygen utilization is roughly proportional to the reduction in cerebral blood flow. (nih.gov)
An occluded MCA led to reduction in both the CBF and cerebral metabolic rate of oxygen. (ajnr.org)
A reduction in cerebral blood flow in brain tissue is typically accompanied by a compensatory increase in the oxygen extraction fraction (OEF) to maintain normal neuronal function. (ajnr.org)

The Alzheimer's Disease Connectome Project (ADCP) will collect data from participants who range from cognitively healthy to those with dementia due to Alzheimer's disease. (humanconnectome.org)
The goal is to develop robust technology to accurately stage Alzheimer's disease across the full spectrum of its progression on an individual subject basis. (humanconnectome.org)
Approximately 70% of participants will also undergo lumbar puncture to determine levels of Alzheimer's disease related proteins in cerebrospinal fluid (phosphorylated tau and abeta42). (humanconnectome.org)
Participants will comprise 300 participants (ages 55+) who fall into three groups: 1) healthy older adult control, 2) participants with mild cognitive impairment, and 3) participants with dementia due to Alzheimer's disease. (humanconnectome.org)
Staging Alzheimer's Disease Risk by Sequencing Brain Function and Structure, Cerebrospinal Fluid, and Cognition Biomarkers. (humanconnectome.org)
This study aims to develop a composite biomarker that can accurately measure the sequential biological stages of Alzheimer's disease (AD) on an individual level. (humanconnectome.org)
We selected 144 subjects from the Alzheimer's Disease Neuroimaging Initiative 2 datasets. (humanconnectome.org)
Functional magnetic resonance imaging (fMRI) techniques can be used to assess cerebrovascular dysfunction in Alzheimer's disease, an important and early contributor to pathology. (uzh.ch)
Thus, pericyte degeneration as seen in neurological disorders such as Alzheimer's disease may contribute to neurovascular dysfunction and neurodegeneration associated with human disease. (nature.com)
Zlokovic, B.V. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. (nature.com)

Cerebral blood flow (CBF) is an indirect marker of neuronal function. (frontiersin.org)
Interruption of regional blood flow within the brain can rapidly cause irreparable neuronal damage. (elifesciences.org)

The cardiovascular health, the presence of various cardiovascular diseases, and their effect on MS cognitive performance are further explored. (ccsvi.nl)
Cardiovascular diseases (hereinafter CVD) are the main reason for early loss of work capacity (at an age below 65) and death in Estonia. (who.int)
The experience of other countries shows that cardiovascular diseases can be reduced by long-term programmes covering multiple disciplines and enlisting the population extensively. (who.int)
to provide the prerequisites and conditions for each child born in this millennium to enable him or her to live to at least an age of 65 without suffering from avoidable cardiovascular diseases. (who.int)
Cardiovascular diseases are the main cause of premature deaths and disability throughout the world. (who.int)
Type 2 diabetes, which is the most common form, can be life threatening due to its complications, particularly, cardiovascular diseases. (who.int)
In the African Region, efforts made to create an environment that enhances the fight against diabetes include adoption of resolutions AFR/RC50/R4 on noncommunicable diseases: strategy for the African Region, in 2000, and AFR/RC55/R4: cardiovascular diseases in the African Region, in 2005. (who.int)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention convened panels of anthrax experts to review and update guidelines for anthrax postexposure prophylaxis and treatment. (cdc.gov)
In the United States, use of IV artesunate is monitored by the Centers for Disease Control and Prevention (Atlanta, GA, USA) under an investigational new drug protocol ( 12 ). (cdc.gov)

6 Severe arterial hypotension produces bilateral infarction in the boundary or watershed zones between major arterial territories. (vin.com)

They concluded that cerebral revascularization may be done safely at high-volume cerebrovascular centers for high-risk patients for whom optimal medical therapy has failed, and that further research must be done to develop an improved method of risk stratification for patients with symptomatic atherosclerotic cerebrovascular steno-occlusive disease to determine which patients may benefit from intervention. (medscape.com)
Global and regional brain network characters were compared between patients with CSVD and healthy control. (bmj.com)
9. Hypoxic hepatitis during the perioperative period in patients with severe pulmonary disease and cor pulmonale. (yumc.ac.kr)
[ 31 , 32 ] Such events occur despite heparinization and placement of a temporary shunt to maintain cerebral perfusion during reconstruction, an essential step in high-risk patients. (medscape.com)
Mortality rates in diabetic patients have been estimated to be up to 5 times greater than in nondiabetic patients, often related to the end-organ damage caused by the disease. (medscape.com)
Pneumocystis pneumonia was the most common respiratory disease (8.8%), while cerebral toxoplasmosis was diagnosed in 8.4% of patients. (who.int)
A single-center, randomized controlled trial of pediatric patients with acute lung injury after surgery for congenital heart disease who will receive prone position ventilation or usual care (control group). (springer.com)
La vitesse d'écoulement du flux sanguin et l'index de pulsatilité ont été mesurés dans les artères carotides internes intercrâniennes, les artères basilaires et cérébrales moyennes d'un échantillon de 141 patients diabétiques sans autre facteur de risque et de 132 témoins en bonne santé appariés pour l'âge et le sexe. (who.int)
Les patients ont été répartis en deux groupes : 73 patients souffrant d'un diabète compliqué dans le premier groupe et 68 patients atteints d'un diabète non compliqué dans le deuxième groupe. (who.int)
[ 3 , 4 , 5 ] As data regarding the risks (and also safety) of noncardiac surgery in patients with PH continue to accumulate, it is imperative for anesthesiologists to be well versed in the disease and its sequelae. (medscape.com)
Patients with acute viral infections (eg, coronavirus disease 2019 [COVID-19]) should delay screening/enrollment until the acute infection has resolved. (who.int)
Patients enrolled in areas where malaria is prevalent must be on malaria prophylaxis based on regional guidance and resistance results. (who.int)
Regional dGEMRIC analysis in patients at risk of osteoarthritis provides additional information about activity related changes in cartilage structure. (lu.se)

With the advances of magnetic resonance technology, the CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen can be measured in MRI. (ajnr.org)
Arterial spin-labeling and SWI sequences were used to acquire CBF, oxygen extraction fraction, and cerebral metabolic rate of oxygen. (ajnr.org)
When this offset a decrease in CBF, the cerebral metabolic rate of oxygen remained at a normal level. (ajnr.org)

Peripheral arterial oxygen saturation (SpO 2 ) and heart rate were measured using pulse oximetry (Nellcor N200) and regional oxygen saturation of the brain (rSO 2 brain) were measured (Invos 5100) between the 3rd and15th minutes and recorded every minute. (bmj.com)

Cerebral endothelium is probably one of the most specific types but until recently it was impossible to determine its function. (hindawi.com)
L-Arginine induces vasodilatation through enhanced production of nitric oxide (NO) in the cerebral endothelium. (hindawi.com)
Cerebral endothelium is probably one of the most specific types since it is the crucial element of the well-known blood-brain barrier. (hindawi.com)
Cerebral endothelium is a one cell layer on the inner wall of the vessels and as such is a difficult subject to image. (hindawi.com)

Handgrip exercise (HG), a small muscle exercise, improves cognitive function and is expected to provide a useful exercise mode to maintain cerebral health. (waseda.jp)

In both white and gray matter, cerebral blood volume decreases by about 0.50% per year with increasing age. (wikipedia.org)

the impairment may be global or regional. (vin.com)
AD is a genetic and sporadic neurodegenerative disease that is a common cause of cognitive impairment acquired in midlife and in late life, but its clinical impact is modified by other neurodegenerative and cerebrovascular conditions. (medscape.com)

Background: Hand, foot, and mouth disease (HFMD), classically a childhood viral infection, has an atypical and severe clinical presentation in adults. (cdc.gov)
Systematic data are not available for safety and efficacy of IV artesunate for treatment of severe P . falciparum malaria outside disease-endemic areas. (cdc.gov)
Severe malaria is rare outside disease-endemic regions. (cdc.gov)

Routine structural neuroimaging evaluation has long been based on nonspecific features such as atrophy, which is a late feature in the progression of the disease. (medscape.com)
The Pediatric Regional Epilepsy Program (PREP) at CHOP specializes in the diagnosis, evaluation and treatment of infants, children and adolescents with seizures and epilepsy. (chop.edu)
Transcranial Doppler sonography is used for evaluation of cerebral blood flow changes. (hindawi.com)

In addition, imaging of the cerebral function became possible by functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) scan. (hindawi.com)

Peripheral angiography segment revenue is expected to expand at a rapid CAGR over the forecast period, attributable to rising prevalence of peripheral arterial diseases and increasing use of peripheral angiography procedure to identify and evaluate blockage or any abnormalities in leg, arm, or neck. (reportsanddata.com)

A clear tomographic depiction of cerebral blood volume distribution in human subjects can achieve by using emission computed tomography, which provides real-time measurements of the cerebral hemodynamic parameters. (wikipedia.org)
Cerebral blood volume measurements are based on methods used in dynamic computed tomography. (wikipedia.org)
Numerous studies are under way to identify specific imaging markers for different types of dementia, including cerebral volumetric measurements, diffusion imaging, spectroscopy, very-high-field MRI scans of senile plaques, and PET scan markers of senile plaques. (medscape.com)

Expert opinion: Cardiovascular pathology significantly contributes to worse clinical and MRI-derived disease outcomes in MS. Global and regional cerebral hypoperfusion may be associated with poorer physical and cognitive performance. (ccsvi.nl)

The ratio between cerebral blood flow and cerebral blood volume can be an accurate predictor of decreased cerebral perfusion pressure, thereby predicting cerebral circulation. (wikipedia.org)
The cerebral circulation exhibits unique capabilities that allows it to adjust to varying environmental conditions and pathophysiological situations so as to maintain optimal perfusion and minimize such injury. (elifesciences.org)

As a result, transient hypotension and acidosis can occur [ 4 , 5 ], and serious cerebral complications can be induced [ 3 , 6 , 7 ]. (medsci.org)

We compared resting CBF measured with pulsed arterial spin labeling in 21 RAN and 16 healthy comparison women (CW) when hungry (after a 16-h fast) and after a meal. (frontiersin.org)
Both OEF and CBF can be determined using MR susceptometry and arterial spin-labeling (ASL). (ajnr.org)
Continuous arterial spin labeling at the human common carotid artery: The influence of transit times. (mpg.de)
Continuous arterial spin labeling using a local magnetic field gradient coil. (mpg.de)

The cerebral blood volume maps can be calculated by dynamic magnetic resonance image set obtained by echo planar imaging after intravenous injection of thiol contrast agent. (wikipedia.org)
Coronal, T1-weighted magnetic resonance imaging (MRI) scan in a patient with moderate Alzheimer disease. (medscape.com)
Rising preference for less invasive surgical and transcatheter procedure to treat various cardiovascular conditions such as aortic disease, coronary and valvular diseases is driving adoption of computed tomography, Doppler ultrasound, magnetic resonance imaging, nuclear imaging among others. (reportsanddata.com)

fMRI methods revealed the functional deficit in disease condition and were useful tools to monitor the treatment response. (uzh.ch)
Ultrasound remains the ultimate method for real time functional cerebral blood flow imaging. (hindawi.com)

The results show that, in the Soptimal, hippocampal and posterior cingulate cortex network biomarkers occur first, followed by aberrant cerebrospinal fluid amyloid-β and p-tau levels, then cognitive deficit, and finally regional gray matter loss and fusiform network abnormality. (humanconnectome.org)
These areas are the cerebral cortex, the hippocampus, the amygdala, several basal and thalamic nuclei, and the cerebellar cortical Purkinje cells. (vin.com)
The human brain owes its characteristic wrinkled appearance to its outer layer, the cerebral cortex. (biotechnology.report)
During human evolution, the neocortex, the evolutionarily youngest part of the cerebral cortex, expanded dramatically and had to fold into wrinkles to fit inside the restricted space of the skull. (biotechnology.report)

Carotid artery disease in NIDDM diabetes. (who.int)

Etomidate induction is associated with a transient 20% to 30% decrease in cerebral blood flow. (nih.gov)

Activity in cerebral or cerebellar or control extra-cranial tissue (subcutaneous fat) did not predict the risk of CVD. (pace-cme.org)

In Phase I (calibration phase), arterial and jugular bulb venous blood were obtained for co-oximetry simultaneously with NIRS signals to calibrate an algorithm for NIRS regional cerebral saturtion (rScO 2 ) to a weighted average cerebral saturation (SavO 2 = 0.7 SjO2 + 0.3 SaO 2 ). (nonin.com)
Duplex ultrasound of the (A) ICA and (B) VA for regional CBF quantification, that, combined with measures of brain venous blood from the IJV. (ubc.ca)

Areas covered: This review summarizes the cardiovascular involvement in MS pathology, its disease activity and progression. (ccsvi.nl)
In similar fashion, the emerging evidence of a higher incidence of extracranial arterial pathology and its association with brain MS pathology are discussed. (ccsvi.nl)

The purpose of this study is to evaluate the feasibility and effectiveness of prone position ventilation in infants who develop postoperative acute lung injury after surgery for congenital heart disease. (springer.com)
This study will investigate the feasibility and effectiveness of prone position ventilation techniques in children who develop postoperative acute lung injury after surgery for congenital heart disease. (springer.com)
The results may help inform strategies to improve airway management after surgery for congenital heart disease. (springer.com)
Pediatric acute lung injury (PALI) is a common complication of congenital heart disease that presents with refractory hypoxemia. (springer.com)

New neuroimaging methods not only facilitate diagnosis of the most common neurodegenerative conditions (particularly AD) after symptom onset but also show diagnostic promise even at very early or presymptomatic phases of the disease. (medscape.com)
In the past few decades the immense development of neuroradiological methods enabled better imaging of cerebral blood vessels. (hindawi.com)

Alzheimer disease is a progressive neurodegenerative disorder characterized by gradual onset of dementia . (medscape.com)
Professor Jackson's main areas of clinical interest include neuro-oncology, neurovascular and neurodegenerative diseases, as well as the development and testing of advanced imaging techniques including CT, MRI and PET imaging. (beardsandjackson.com)
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. (ccsvi.nl)
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by motor dysfunction (parkinsonism) and several non-motor features. (bmj.com)

Anatomy42

Organisms8

Diseases63

Chemicals and Drugs41

Analytical, Diagnostic and Therapeutic Techniques and Equipment64

Psychiatry and Psychology10

Phenomena and Processes29

Anthropology, Education, Sociology and Social Phenomena2

Information Science2

Health Care20

Geographicals1

Vascular17

Intracranial9

Ischemic5

Small vessel disease6

Arteries8

Vessel3

Aneurysms1

Ischemia4

Autoregulation3

Stenosis1

Pathophysiology4

Mean arterial5

Changes in cerebral2

Endothelial function13

Regulation of cerebral bloo3

Measuring cerebral blood volume1

Characterizing Alzheimer's disease1

Perfusion MRI1

Brain tumors1

Oxygenation4

Stroke5

Metabolism3

Reduction4

Alzheimer's10

Neuronal2

Cardiovascular diseases7

Centers for Diseas3

Infarction1

Patients13

Metabolic Rate3

Pulse oximetry1

Endothelium4

Maintain cerebral1

Decreases1

Impairment2

Severe3

Evaluation3

Positron emission t1

Prevalence1

Measurements3

Hypoperfusion1

Circulation2

Hypotension1

Spin4

Magnetic3

Functional2

Cortex4

Carotid artery1

Transient1

Extra cranial1

Venous blood2

Pathology2

Congenital heart d4

Methods2

Neurodegenerative4