BenzamidesPiperazinesPyrimidinesLeukemia, Myelogenous, Chronic, BCR-ABL PositiveGastrointestinal Stromal TumorsFusion Proteins, bcr-ablAntineoplastic AgentsProto-Oncogene Proteins c-kitProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor alphaLeukemia, Myeloid, Chronic-PhaseReceptor, Platelet-Derived Growth Factor betaDrug Resistance, NeoplasmBlast CrisisGenes, ablHypereosinophilic SyndromeCytogenetic AnalysisProto-Oncogene Proteins c-ablProtein-Tyrosine KinasesHypopigmentationK562 CellsGastrointestinal NeoplasmsTreatment OutcomePhiladelphia ChromosomeLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeRemission InductionReceptors, Platelet-Derived Growth FactorDermatofibrosarcomaMastocytosis, SystemicDose-Response Relationship, DrugDrug ApprovalEnzyme InhibitorsDrug Administration ScheduleDisease-Free SurvivalAntineoplastic Combined Chemotherapy ProtocolsPregnatrienesCell Line, TumorThiazolesFibromatosis, AggressiveProto-Oncogene Proteins c-sisAdministration, OralHarringtoninesLeukemia, Myeloid, Accelerated PhaseTime FactorsApoptosisSurvival AnalysisInterferon-alphaCell ProliferationLichenoid EruptionsTreatment FailureDrug SynergismSalvage TherapymRNA Cleavage and Polyadenylation FactorsNeoplasm, ResidualPrognosisPhosphorylationSurvival RateMutationRecurrenceKetonesDisease ProgressionRifabutinPyrrolesCytogeneticsFuransGene Expression Regulation, LeukemicCombined Modality TherapyUnited States Food and Drug AdministrationFollow-Up StudiesPrimary MyelofibrosisPrecursor Cell Lymphoblastic Leukemia-LymphomaHydroxyureaIn Situ Hybridization, FluorescenceChromosomes, Human, Pair 9Reverse Transcriptase Polymerase Chain ReactionNeoplastic Stem CellsSTAT5 Transcription FactorPlatelet-Derived Growth FactorCytarabineScleroderma, SystemicNeoadjuvant TherapyInhibitory Concentration 50Transplantation, HomologousStem Cell FactorHistiocytoma, Malignant FibrousSignal TransductionRNA, MessengerIndolesMyeloid Progenitor CellsHematopoietic Stem Cell TransplantationBlood Cell CountFibrosisCell SurvivalImmunohistochemistryGraves OphthalmopathyOncogene Proteins, FusionAntigens, CD34BleomycinClinical Trials as TopicBone Marrow