CD34+ Cell Therapy for No-Option Refractory Disabling Angina: Time for FDA Approval? (crtonline.org)
Progenitor cell therapy is being investigated for the treatment of damaged myocardium resulting from acute or chronic cardiac ischemia and for refractory angina. (southcarolinablues.com)
For individuals who have refractory angina who receive progenitor cell therapy, the evidence includes phase 2 trials and a phase 3 pivotal trial. (southcarolinablues.com)
Additional larger trials are needed to determine whether progenitor cell therapy improves health outcomes in patients with refractory angina. (southcarolinablues.com)
So signs phase II study to 125 Restenosis in these angina or oral dabigatran or from with severe entities such start the remains the you should major contributor. (acaringtouchboardandcare.com)
A. Being invasive, CS Reducing device once approved, should always be a second line therapy indicated after failure of MMT in refractory angina pts. (ccclivecases.org)
It is appropriate for refractory angina pts with no treatable epicardial disease and is likely due to diffuse small vessel disease. (ccclivecases.org)
At the same time, the use of tirofiban as an adjunctive medication in the catheterization laboratory (Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis [RESTORE] regimen) for the prevention of ischemic complications during percutaneous coronary intervention (PCI) gave controversial results. (jacc.org)
Thrombosis5
However, There were still 8.0 % (5/62) of the patients with poor outcomes, including optic disc atrophy in 3 patients and stent-interior thrombosis in 2 patients, which occurred 6.3 months after stenting. (benthamscience.com)
Efficacy of stenting in patients with cerebral venous sinus thrombosis-related cerebral venous sinus stenosis. (benthamscience.com)
Mortality, major adverse cardiovascular events (MACEs), target vessel failure, and stent thrombosis (ST) occur more frequently as the result of calcium-mediated poor lesion preparation, stent under expansion, and stent malapposition ( 2 ). (frontiersin.org)
This procedure had major drawbacks such as acute vessel closure due to arterial recoil, coronary artery dissection, acute arterial thrombosis, and restenosis due to neointimal hyperplasia. (statpearls.com)
8 - 10 Because this finding may be associated with adverse clinical events such as late stent thrombosis 10 , 11 in the coronary circulation, we sought to identify the presence of any ISA within the intracranial circulation in patients undergoing stent-mediated coiling by using the self-expanding intracranial EN (Cordis, Miami Lakes, Florida). (ajnr.org)
Renal artery3
Up to 60% of patients with TA have renal artery involvement, often resulting in refractory hypertension (HTN) and impaired renal function 4 , 5 , 6 . (jrheum.org)
Therefore, our study analyzed longterm outcomes and clinical variables associated with poor outcomes (e.g., refractory HTN, chronic renal insufficiency, or death) in all patients with TA-associated renal artery involvement, regardless of whether they underwent revascularization procedures. (jrheum.org)
Is there still a role for renal artery stenting in the management of renovascular hypertension - A single-center experience and where do we stand? (crtonline.org)
Coronary Stent1
The coronary stent was first developed in the 1980s and has continued to evolve in terms of shape, structure, and the material used within them. (statpearls.com)
Drug-elutin1
Not only has the rate of primary PCI increased over the years, but progress in device technologies and adjunctive pharmacology has also improved the pro- cedural success rate - for example, the availability of stents and second generation drug eluting stents, thrombus aspiration devices, and safer and more effective periprocedural anticoagulation/antiplatelet treatments. (romanianjournalcardiology.ro)
Placement1
The mean trans-stenotic pressure gradients were 6~43 mmHg prior to stenting and returned to 0~4 mmHg after stent placement. (benthamscience.com)
Balloon6
Revascularization procedures, including balloon angioplasty with or without stenting, are often used for the treatment of steno-occlusive lesions 6 , 7 , 8 . (jrheum.org)
They recruited 212 patients with intermittent claudication who had never had invasive treatment-which immediately made me realise the study couldn't have been done in America, where at the first twinge of calf pain you get a stent or balloon stuck down your femoral artery. (bmj.com)
A total of 87 de novo lesions were treated by IVL with the following indications: 25 before attempting other balloon-based devices (primary IVL), 51 after the failure of non-compliant balloon dilatation (secondary IVL), and 11 after stent implantation because of stent under expansion (bailout IVL). (frontiersin.org)
In a pre-stent era, balloon angioplasty was the mainstay of coronary revascularization in which an inflatable balloon-tipped catheter was inserted percutaneously through an arterial entry site in the extremity and advanced into the coronary arteries. (statpearls.com)
For endovascular rescue therapy (ERT), the intra-arterial (IA) administration of vasodilators and the use of transluminal balloon angioplasty (TBA) are proven techniques to treat severe and refractory CVS. (bmj.com)
Paclitaxel-coated balloon catheter versus paclitaxel-coated stent for the treatment of coronary in-stent restenosis. (ihr-herz.de)
PTCA1
Left ventricular diastolic function parameters after PTCA and stent Implantation. (ihr-herz.de)
Versus2
The experimental use of everolimus in refractory chronic graft-versus-host disease was reported in 2012. (wikipedia.org)
Univariate analysis revealed ISA in the ICA to correlate with a large stent-subtended angle, a small curvature radius, and a large diameter but not stent length or jailing versus a sequential technique. (ajnr.org)
Lesion3
Target lesion failure may be more frequent when IVL is performed for the treatment of ISR due to calcium-mediated stent under expansion. (frontiersin.org)
Other stents like bifurcation stents and covered stents are designed for special circumstances such as lesion over vascular bifurcation or coronary artery perforation, respectively. (statpearls.com)
Patient is now planned for staged PCI of LAD and Diagonal bifurcation lesion using rotational atherectomy and dedicated two stent technique. (ccclivecases.org)
Implantation1
The stent implantation rate in group A was significantly lower than that in group B (4.2% vs. 50% in lesions, P (bvsalud.org)
Outcomes in patients1
However, there is a lack of evidence of the long-term good outcomes in patients with CVSS who underwent stenting. (benthamscience.com)
Vessel7
Little data are available on the ability of the stent struts to maintain vessel-wall apposition once deployed in the tortuous cerebral vasculature and the prevalence of ISA. (ajnr.org)
The purpose of this study was to evaluate the relationship between geometric features of the parent vessel at the stent deployment site and prevalence of ISA. (ajnr.org)
Parent vessel diameter, curvature radius, and stent-subtended arc angle were measured at the site of deployment and analyzed for prediction of ISA in the ICA. (ajnr.org)
In this study, ISA was detectable by 3T-MRA in a significant proportion of patients undergoing EN stent-assisted coiling of ICA aneurysms in a vessel geometry− and stent-deployment location−dependent manner. (ajnr.org)
1 - 4 Stents serve as a physical barrier to prevent coil protrusion into the parent vessel during coiling of wide-neck or fusiform lesions. (ajnr.org)
Several studies have evaluated the architecture of stents within coronary vessels and have noted the presence of ISA to the vessel wall. (ajnr.org)
Correlating our findings with angiographic FPCT, we describe here a new crescent-shaped flow signal intensity external to the stent struts on 3T-MRA as a marker for ISA in EN-treated aneurysms and describe the morphologic characteristics of target vessels that predispose to poor stent−vessel wall apposition. (ajnr.org)
Incidence1
The symptoms and signs of IH prior to stenting and post-stenting and the incidence of restenosis after stenting were analyzed. (benthamscience.com)
Aneurysms2
Flexible microstents, such as the closed-cell EN, have facilitated adjunctive coiling of intracranial aneurysms. (ajnr.org)
Endovascular embolization using a stent-assisted technique has proved to be an effective option in the treatment of wide-neck intracranial aneurysms. (ajnr.org)
Patients11
Methods: A total of 62 patients with imaging confirmed non-thrombotic and non-external compression CVSS were enrolled into this single center real-world cohort study after undergoing stenting, and were continuously followed up for more than 12 years. (benthamscience.com)
42% of the patients suffered from visual loss, 11.3% pulsatile tinnitus, and 96.8% Papilledema before stenting. (benthamscience.com)
During the following 12~126 months (the median was 62) after stenting of the follow-up, 91.9% (57/62) of the patients obtained good outcomes. (benthamscience.com)
Patients with CVSS may get long-term benefit from stenting, especially when they are accompanied with severe IH. (benthamscience.com)
After a median followup of 90.6 months, 11 (17.7%) of the 62 patients had refractory HTN and 6 (9.7%) had chronic renal insufficiency. (jrheum.org)
However, previous studies on vascular interventions in patients with TA have shown inconsistent results, ranging from a high risk of restenosis to good longterm efficacy and patency, although open revascularization resulted in superior patency rates compared with endovascular intervention 4 , 6 , 9 , 10 , 11 . (jrheum.org)
Postprocedural 3T-MRA was performed in a cohort of 39 patients undergoing EN stent-assisted intracranial aneurysm coiling. (ajnr.org)
Follow-up imaging of patients who have undergone stent-mediated coil embolization procedures has traditionally focused on the presence or absence of residual filling in the dome. (ajnr.org)
Since January 2009, all patients undergoing stent-mediated coiling in our service have routinely undergone prospective 3T-MRA postprocedurally. (ajnr.org)
An additional 6 patients who underwent prospective 3T-MRA imaging within 3 days of EN deployment between June 2007 and September 2008, as part of a pilot study on the utility of 3T-MRA in randomly selected patients following stent-coiling, were also included in the study. (ajnr.org)
Perioperative management of patients with coronary stents undergoing non-cardiac surgery. (ihr-herz.de)
Intracranial4
Background and Purpose: Cerebral Venous Sinus Stenosis (CVSS) usually results in severe Intracranial Hypertension (IH), which can be corrected by stenting immediately. (benthamscience.com)
Intracranial venous sinus stenting for benign intracranial hypertension: Clinical indications, technique, and preliminary results. (benthamscience.com)
5 Despite excellent laboratory evaluations of stent conformation in vitro, 6 , 7 data on visualization and strut configuration of stents deployed in the intracranial circulation remain scant. (ajnr.org)
All aneurysm stent-coiling procedures using ENs in the intracranial vasculature from January 2009 to September 2010 with 3T-MRA performed within 3 days of stent deployment, totaling 33 cases, were included. (ajnr.org)
Efficacy1
This finding probably reflects the suboptimal platelet inhibition when tirofiban is employed at RESTORE (Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis) regimen. (jacc.org)
Vascular1
With the introduction of coronary stents, coronary dissection and vascular recoil were eliminated due to the expandable, metallic meshwork of the stent, which prevents negative remodeling. (statpearls.com)
Chronic1
Poor outcome was defined as refractory HTN, chronic renal insufficiency, or death. (jrheum.org)
Therapy3
Despite dual therapy, however, her symptoms recurred frequently and were refractory to further medical treatment. (surgicalneurologyint.com)
Conclusion: Our data suggest that stenting may be a promising therapy for CVSS correcting. (benthamscience.com)
Progressive stenosis of the pulmonary veins after repair of total anomalous pulmonary venous drainage is frequently refractory to surgical therapy. (nih.gov)
Stenosis2
To our knowledge, this is the first report of carotid artery stenting (CAS) for the treatment of kinking stenosis after CEA. (surgicalneurologyint.com)
Coronary stents (CS) are expandable tubular metallic devices which are introduced into the coronary arteries that demonstrate stenosis due to an underlying atherosclerosis disease. (statpearls.com)
Treatment2
After 3 months, she had suffered transient ischemic attacks that were refractory to medical treatment, so we performed CAS to prevent future events. (surgicalneurologyint.com)
In 23 lesions, IVL was used for the treatment of in-stent restenosis (ISR). (frontiersin.org)
Procedure1
Q How much would you expect the restenosis rate for the LAD procedure performed today? (ccclivecases.org)
Months2
The kinked ICA was immediately resolved by stenting and there was no restenosis at a follow-up angiogram 19 months later. (surgicalneurologyint.com)
While DEB has only antiproliferative drug coating without an underlying metallic structure of the stent, BRS is also devoid of metallic structure and is entirely resorbed in a few months after serving their purpose. (statpearls.com)
Technique1
2 of the 3 survivors were repaired with a novel technique creating a sutureless neoatrium without evidence of restenosis at 1.8 years' follow-up. (nih.gov)
Results1
Results from the carotid artery stent (CAS)-registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK). (ihr-herz.de)
Site2
In this report, we present a case of successful ICA course repair achieved by deploying a stent at the site of the kink. (surgicalneurologyint.com)
Commonly used drugs act to block signal transduction and cell cycle progression in different phases, thereby blocking smooth muscle cell (SMC) proliferation or intimal hyperplasia in the stented arterial site. (statpearls.com)
Case1
We present the details of a case successfully treated by carotid artery stenting (CAS). (surgicalneurologyint.com)