• By means of microelectrode techniques the electrophysiological effects of beta blocking agents, sotalol and metoprolol, were studied on isolated rabbit right atrium-atrioseptum preparations. (eurekamag.com)
  • Background Mechanisms and changes of electrophysiological (EP) characteristics in successful radiofrequency (RF) modification of right midseptal and posteroseptal areas for controlling rapid ventricular response to atrial fibrillation (Af) are not clear. (ahajournals.org)
  • 18 19 20 Almost all the patients in these studies had chronic atrial fibrillation, and evaluation of AV node electrophysiological properties after successful modification procedures was impossible. (ahajournals.org)
  • Background In this study we tested the hypothesis that atrial fibrillation (AF) causes electrophysiological changes of the atrial myocardium which might explain the progressive nature of the arrhythmia. (ahajournals.org)
  • A possible explanation for all these epidemiological and clinical observations is that, apart from the progressive changes due to an underlying heart disease, atrial fibrillation itself causes progressive electrophysiological and/or structural changes to the atria, which promote the initiation or perpetuation of atrial fibrillation. (ahajournals.org)
  • There has also been evidence of prolonged budiodarone cardiac effect days after drug discontinuation as the atrial fibrillation baseline measurements were not reached in washout periods. (wikipedia.org)
  • Its effects on the refractory period are significantly more substantial, and therefore pilsicainide treatment results in an increased wavelength and termination of atrial fibrillation. (wikipedia.org)
  • Abstract -Combined experimental and theoretical developments have demonstrated that in addition to preexisting electrophysiological heterogeneities, cardiac electrical restitution properties contribute to breakup of reentrant wavefronts during cardiac fibrillation. (ahajournals.org)
  • It has electrophysiological effects of a class III antiarrhytmic drug and it is used as a medicine to increase the Q - T interval of the PQRST heart rhythm in patients with cardiac arrhythmias. (wikipedia.org)
  • In the first phase, a short period of ventricular contraction known as the systole, the tricuspid and mitral valves snap shut, producing the familiar "lub" sound heard in the physician's stethoscope. (thefreedictionary.com)
  • Recently intravenous (IV) Liposomal amphotericin B (L-AmB) has been recommended as monotherapy therapy for refractory coccidioidal meningitis based on its advantages over (AmB-d), however, its intrathecal use has not been reported. (bioportfolio.com)
  • Brief report: Clinical experiences after emergency use of daratumumab monotherapy for relapsed or refractory multiple myeloma in real practice. (bioportfolio.com)
  • Reentry induction was possible for short battery applications when break excitations were slowed and forced to take convoluted pathways upon interaction with refractory tissue from prior make excitations or sinus beats. (ox.ac.uk)
  • If rate and rhythm control cannot be maintained by medication or cardioversion, it may be necessary to perform electrophysiological studies with ablation of abnormal electrical pathways. (wikipedia.org)
  • The refrcactory period of neurons mediating an electrically elicited behavior (self-stimulation) was estimated by varying the intrapair pulse separation in a stimulating train made up of pulse pairs and measuring the intensity of the elicited behavior. (sciencemag.org)
  • Progress in the problem of relapsed or refractory acute myeloid leukemia. (bioportfolio.com)
  • Heavy recreational use of methamphetamine may lead to a post-acute-withdrawal syndrome, which can persist for months beyond the typical withdrawal period. (wikipedia.org)
  • Trending serial CSF samples to guide treatment of refractory coccidioidal meningitis with intrathecal liposomal amphotericin. (bioportfolio.com)
  • Daratumumab is a human CD38-directed monoclonal antibody indicated for the treatment of relapsed and refractory multiple myeloma (MM). (bioportfolio.com)
  • Clinical observation of recombinant human endostatin in treating relapsed refractory multiple myeloma. (bioportfolio.com)
  • Recombinant human endostatin (rhES) can inhibit multiple myeloma, while its clinical efficacy in treating relapsed refractory multiple myeloma (RRMM) has not been assessed. (bioportfolio.com)
  • In electrophysiological models, the axon hillock is included with the initial segment of the axon where membrane potentials propagated from synaptic inputs to the dendrites or cell body are summed. (wikipedia.org)
  • A recent detailed analysis of the unique population of M cells in the ventricular midmyocardium 2 3 4 5 6 revealed electrophysiological features intermediate between those of myocardial and specialized conducting (Purkinje) fibers. (ahajournals.org)
  • They depend on the proportion of sensitive cells (that are not refractory) and on the proportion of these cells receiving at least threshold excitation. (wikipedia.org)
  • We define refractory nasopharyngeal carcinoma as the following: recurrence with radiation brain injury after radiotherapy, recurrence after the second or more courses of radiotherapy, stan. (bioportfolio.com)