• Ribeiro KB, Buffler PA, Metayer C. Socioeconomic status and childhood acute lymphocytic leukemia incidence in São Paulo, Brazil. (medscape.com)
  • Lymphomas, lymphocytic leukemias, and myeloma are from the lymphoid line, while acute and chronic myelogenous leukemia, myelodysplastic syndromes and myeloproliferative diseases are myeloid in origin. (wikipedia.org)
  • For instance, B-cell chronic lymphocytic leukemia (CLL) and B-cell small lymphocytic lymphoma (SLL) are different manifestations of the same neoplasm, as are lymphoblastic lymphomas and T-cell acute lymphocytic leukemias. (medscape.com)
  • Acute lymphoblastic leukemia (ALL) is a systemic disease, and treatment is primarily based on chemotherapy. (medscape.com)
  • Thus, surgical care is generally not required in the treatment of ALL, except for the placement of a central venous catheter for administering chemotherapy, blood products, and antibiotics, and for obtaining blood samples. (medscape.com)
  • Before and during the initial induction phase of chemotherapy, patients may develop tumor lysis syndrome , which refers to the metabolic derangements caused by the systemic and rapid release of intracellular contents as chemotherapy destroys leukemic blasts. (medscape.com)
  • The phases and duration of chemotherapy for acute lymphoblastic leukemia (ALL) are briefly discussed in this section. (medscape.com)
  • The more aggressive forms of disease require treatment with chemotherapy, radiotherapy, immunotherapy and-in some cases-a bone marrow transplant. (wikipedia.org)
  • Patients who present with aggressive forms of NHL, or whose disease converts to an aggressive form, may achieve complete remission with combination chemotherapy regimens, with or without aggressive high-dose consolidation therapy with marrow or stem cell support. (medscape.com)
  • Leukemia Basophilic A rare acute myeloid leukemia in which the immature cells differentiate towards basophils. (nih.gov)
  • Malignant C6923 Acute Bilineal Leukemia Acute Bilineal Leukemia An acute leukemia of ambiguous lineage in which there is a dual population of blasts with each population expressing markers of a distinct lineage (myeloid and lymphoid or B-and T-lymphocyte). (nih.gov)
  • WHO, 2001) -- 2003 Malignant C4673 Acute Biphenotypic Leukemia Acute Biphenotypic Leukemia An acute leukemia of ambiguous lineage characterized by blasts which coexpress myeloid and T or B lineage antigens or concurrent B and T lineage antigens. (nih.gov)
  • M6 Acute Myeloid Leukemia An acute myeloid leukemia characterized by a predominant immature erythroid population. (nih.gov)
  • Acute Leukemia of Indeterminate Lineage An acute leukemia in which the blasts lack sufficient evidence to classify as myeloid or lymphoid or they have morphologic and/or immunophenotypic characteristics of both myeloid and lymphoid cells. (nih.gov)
  • However, in some cases acute myeloid leukemia (AML) demonstrates APL-like morphological features such as atypical promyelocytes accumulation. (bvsalud.org)
  • INTRODUCTION: B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common neoplasm in children. (bvsalud.org)
  • Acute lymphoblastic leukaemia. (medscape.com)
  • A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial. (medscape.com)
  • Because these tissues are all intimately connected through both the circulatory system and the immune system, a disease affecting one will often affect the others as well, making aplasia, myeloproliferation and lymphoproliferation (and thus the leukemias and the lymphomas) closely related and often overlapping problems. (wikipedia.org)
  • citation needed] Historically, hematological malignancies have been most commonly divided by whether the malignancy is mainly located in the blood (leukemia) or in lymph nodes (lymphomas). (wikipedia.org)
  • Aggressive lymphomas are increasingly observed in patients who are HIV positive, and treatment of these patients requires special consideration. (medscape.com)
  • Both lymphomas and lymphoid leukemias are included in this classification because both solid and circulating phases are present in many lymphoid neoplasms and distinction between them is artificial. (medscape.com)
  • In patients with B-precursor ALL, bone pain, arthritis, and limping may be presenting symptoms and in 5% of patients are the only symptoms, leading to delays in diagnosis. (medscape.com)
  • 1) precursor B-cell neoplasms, which include B lymphoblastic leukemia/lymphoma with or without recurrent genetic abnormalities, and (2) mature B-cell neoplasms. (medscape.com)
  • This commonly leads to a different approach in diagnosis and treatment of hematological malignancies. (wikipedia.org)
  • The use of rituximab has been established for the treatment of B-cell-derived hematologic malignancies, including follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). (wikipedia.org)
  • NHLs are a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment. (medscape.com)
  • Acute promyelocytic leukemia (APL) pathogenesis is based on RARA gene translocations, which are of high importance in the diagnosis of and proper therapy selection for APL. (bvsalud.org)
  • There are two subtypes recognized: erythroleukemia and pure erythroid leukemia. (nih.gov)
  • In patients with T-lineage ALL, respiratory distress and stridor secondary to a mediastinal mass may be a presenting symptom. (medscape.com)
  • The presence of stridor is cause for concern and may signify a mediastinal mass, found in half of patients with T-lineage ALL, with a risk of imminent respiratory arrest. (medscape.com)
  • Triple intrathecal therapy (methotrexate/hydrocortisone/cytarabine) does not improve disease-free survival versus intrathecal methotrexate alone in children with high risk B-lymphoblastic leukemia: results of Children's Oncology Group Study AALL1131. (medscape.com)
  • Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group. (medscape.com)
  • Using this approach, we examined questionable monocytic populations in five patients with dominant leukemic populations of B-lymphoblastic origin. (bvsalud.org)
  • PMID- 3504195 TI - [Prazosin in the treatment of chronic heart failure]. (nih.gov)
  • Patients with this type of diffuse large B-cell lymphoma are reported to have a less favorable outcome compared to those with a germinal center B-cell expression profile, with a 5-year survival rate of 35% and a median survival of 2 years. (nih.gov)
  • Different forms of ALL require different approaches for optimal results, nevertheless ALL treatment typically consists of a remission-induction phase, intensification (consolidation) phase, and continuation therapy targeted at eliminating residual disease. (medscape.com)
  • Patients at high risk for tumor lysis still need to excrete preexisting uric acid, which is unaffected by the use of allopurinol. (medscape.com)
  • Campana D. Role of minimal residual disease monitoring in adult and pediatric acute lymphoblastic leukemia. (medscape.com)
  • [ 2 ] Although relapse is common in advanced-stage NHL, patients can often be retreated with considerable success as long as the disease histology remains low grade. (medscape.com)
  • The risk of late relapse is higher in patients with a divergent histology of both indolent and aggressive disease. (medscape.com)
  • Initially transfer children to a facility in which they can be in the care of a pediatric oncologist, preferably a center that participates in multi-institutional clinical trials. (medscape.com)
  • This approach is able to identify implicit cases of MPAL and therefore leads to the necessary clinical management for patients. (bvsalud.org)
  • PMID- 3504191 TI - [Clinical overview of the present state of treatment of cardiac insufficiency using vasodilating agents]. (nih.gov)
  • Mixed-phenotype acute leukemia (MPAL), a rare and heterogeneous category of acute leukemia, is characterized by cross-lineage antigen expression. (bvsalud.org)
  • Leukemia-mediated pancytopenia is typically due to marrow replacement of normal hematopoietic precursors, a process known as myelopthisis. (wikidoc.org)
  • A cohort of 203 patients with BCP-ALL was selected based on FISH screening and was studied by karyotyping, FISH, RT-PCR and high throughput sequencing. (bvsalud.org)
  • There are no life-threatening causes of pancytopenia that require acute treatment within 24 hours. (wikidoc.org)
  • Patients commonly present with pallor caused by anemia and petechiae and bruising secondary to thrombocytopenia. (medscape.com)
  • Attempts to lay the patient flat or perform intubation should be avoided, and the patient should commence steroid therapy and be transferred to the pediatric intensive care unit for close observation while workup is underway. (medscape.com)
  • PMID- 3504207 TI - New multidrug regimen with indigenous drugs and dapsone in the treatment of lepromatous leprosy (preliminary report). (nih.gov)