• This state of akinetic mutism varies in intensity, but it is distinguished by drowsiness, lack of motivation, hyper-somnolence, and reduction in spontaneous verbal and motor actions. (wikipedia.org)
  • CASE SUMMARY: A 61-year-old Chinese man initially presented with Korsakoff syndrome, followed by rapid-onset dementia, visual hallucinations, akinetic mutism, myoclonus, and hyperthermia. (bvsalud.org)
  • It usually begins with memory loss, followed by rapidly progressing dementia, loss of coordination, slurred speech and myoclonus, and - in the final stages - akinetic mutism, coma and death. (health.gov.au)
  • Akinetic mutism is a medical condition where patients tend neither to move (akinesia) nor speak (mutism). (wikipedia.org)
  • citation needed] Another cause of both akinesia and mutism is ablation of the cingulate gyrus. (wikipedia.org)
  • citation needed] Akinetic mutism is a symptom during the final stages of Creutzfeldt-Jakob disease (a rare degenerative brain disease) and can help diagnose patients with this disease. (wikipedia.org)
  • Akinetic mutism can occur in the frontal region of the brain and occurs because of bilateral frontal lobe damage. (wikipedia.org)
  • Other causes of akinetic mutism are as follows: Respiratory arrest and cerebral hypoxia Acute cases of encephalitis lethargica Meningitis Hydrocephalus Trauma Tumors Aneurysms Olfactory groove meningioma Cyst in third ventricle Toxical lesions and infections of central nervous system Delayed post-hypoxic leukoencephalopathy (DPHL) Creutzfeldt-Jakob disease (mesencephalic form) Akinetic mutism can be misdiagnosed as depression, delirium, or locked-in syndrome, all of which are common following a stroke. (wikipedia.org)
  • Magnetic resonance imaging of the brain revealed extensive hyperintense signals in the cortex, while positron emission tomography/computed tomography showed a diffuse reduction in cerebral cortex metabolism. (bvsalud.org)
  • Akinetic mutism is often the result of severe frontal lobe injury in which the pattern of inhibitory control is one of increasing passivity and gradually decreasing speech and motion. (wikipedia.org)
  • Suprachiasmatic pressure may cause altitudinal visual field deficits, abulia or akinetic mutism, amnestic syndromes, or hypothalamic dysfunction. (medscape.com)
  • Lack of motor function (but not paralysis) Lack of speech Apathy Slowness Disinhibition Akinetic mutism can be caused by a variety of things. (wikipedia.org)
  • This significant reduction in iCJD was attributed to the 1977 introduction of a highly selective, column chromatography step in the hormone purification protocol that can markedly reduce prion infectivity ( 1 , 2 ). (cdc.gov)
  • The primary findings were a significant increase in the number of ultrashort EEG microstates and a reduction in the average duration of EEG microstates in cognitively impaired and demented patients. (medscape.com)
  • [ 8 ] the term akinetic mutism (AM) has been used to describe a syndrome characterized by marked reduction of nearly all motor functions, including facial expression, gestures, and speech output, but with some degree of alertness. (medscape.com)
  • Several individuals have developed an asymmetric akinetic rigid syndrome with arm and gait dystonia and pyramidal signs that may be related to treatment with neuroleptic drugs. (nih.gov)
  • One of the most disabling late effects of posterior fossa tumour surgery is the cerebellar mutism syndrome (CMS) which has been reported in up to 39% of the patients but the exact incidence is uncertain since milder cases may be unrecognized. (biomedcentral.com)
  • The cerebellar mutism syndrome (CMS) refers to the constellation of transient mutism, ataxia, hypotonia and irritability following surgery for cerebellar or fourth ventricle tumours in children and adolescents [ 7 ]. (biomedcentral.com)
  • The disturbance can range from marked reduction in movements to marked agitation. (medilib.ir)
  • Suprachiasmatic pressure may cause altitudinal visual field deficits, abulia or akinetic mutism, amnestic syndromes, or hypothalamic dysfunction. (medscape.com)