• Some of these agents are being developed for vaginal application, and for rectal use by those engaging in anal sex. (wikipedia.org)
  • Nonoxynol-9 can increase vaginal, cervical, and rectal tissue irritation, which makes HIV infection easier. (hivplusmag.com)
  • Because nonoxynol-9 creates abrasions in the vaginal and rectal walls, it may even make transmission of HIV and other STDs more likely, especially if used frequently. (wikidoc.org)
  • Spermicidal lubricants are not for rectal use or more-than-once-a-day vaginal use. (thepandorasplayhouse.com)
  • The likelihood of heterosexual acquired disease increases with a higher number of sexual partners, contact with intravenous drug users (IVDUs), prostitution, sexual practices that damage vaginal or rectal mucosa, and a previous history of other STDs. (health.am)
  • One of the first substances hoped to be an effective HIV microbicide, the spermicide nonoxynol-9, was shown by several groups, including the World Health Organization and the Centers for Disease Control and Prevention, to have the opposite effect. (hivplusmag.com)
  • Nonoxynol-9 Spermicide Is On This Condom for extra protection against pregnancy ONLY - NOT for extra protection against AIDS and other STDs. (thepandorasplayhouse.com)
  • Nonoxynol-9, a spermicide with some antiviral activity, enhances the protective effects of condoms and should be used in conjunction with condoms either as a spermicidal jelly or impregnated into the latex condom itself. (health.am)
  • Some malecondomsare made with the spermicide nonoxynol 9. (healthiack.com)
  • These condoms contain spermicides, nonoxynol-9, parabens, benzocaine and glycerine just to name a few things. (worldtruth.tv)
  • Spermicidal condoms contain Nonoxynol-9, the substance used in many brands of condoms, lubricants and creams as extra protection against STI's, however recent studies have shown that Nonoxynol-9, may strip the inner lining of the rectum during anal sex, making it more prone to abrasions and open wounds. (endinghiv.org.au)
  • Activities that may lead to damage of the rectal mucosa, such as rectal douching, manual penetration of the rectum ("fisting"), and concomitant ulcerative STDs, increase the likelihood of disease acquisition. (health.am)
  • This Anal Glide from Pjur is perfect for those who want to ease the discomfort of anal play, while still retaining sensitivity in the rectal region. (condomdepot.com)
  • However, they recommend using a nonoxynol-9 lubricated condom over no condom at all. (wikidoc.org)
  • The most common active ingredient of spermicides is nonoxynol-9 . (wikidoc.org)
  • Spermicides containing nonoxynol-9 are available in many forms, such as jelly (gel), films, and foams. (wikidoc.org)
  • Spermicides act to kill sperm and prevent STD's, the problem is that most spermicides contain nonoxynol-9, a chemical that kills skin cells in the vagina and rectal wall which increases the chances of catching an STD or urinary tract infection in the long term. (worldtruth.tv)
  • u003c\/p\u003e\n\u003cp\u003eThe Population Council, in a 2011 study, tested commercially available water-based sexual lubricants, and found that many damaged human rectal cells and that some of them - those containing polyquaternium-15 - appeared to actively increase HIV replication in cell cultures and therefore could raise one's risk of HIV transmission. (mysexshop.co.za)
  • Insertive rectal intercourse, fellatio, and ingestion of semen are associated with HIV transmission to a lesser degree. (health.am)
  • HIV can be transmitted through blood, semen, rectal and. (wrrl-oberes-edertal.de)
  • This can pose serious health risks as tears in the rectal area increase the chances of contracting HIV. (endinghiv.org.au)
  • Previously, it was believed that nonoxynol-9 reduced the risk of HIV infection, as it prevents transmission of the virus in the laboratory. (wikidoc.org)
  • While lemon juice has been proposed as a microbicide based on laboratory studies, [20] human testing has shown that, at the concentrations needed to kill HIV, it causes the same abrasions as nonoxynol-9. (wikidoc.org)
  • 99.75 % ) 13 2 propanol ip: 45 g / isopropanol, 1 propanol: 30 g / n propanol ethyl hexadecyl dimethyl ammonium ethylsulphate: 0.2 g emollient and moisturiser with skin protecting substances 500 ml bott with dispenser passes en 13727, en13624, en14476, en1500, en12791 standards, pack size: 500 ml bottle 14 4 methylumbelliferone ( 100gm ) ( purity ( hplc ) =98 %, mol. (jharkhandtenders.net)
  • Not for rectal (anal) use. (nih.gov)
  • and discouraged anal intercourse without condoms, rectal douching before and after anal intercourse, and the use of 'natural membrane' condoms and petroleum-based lubricants. (cdc.gov)
  • Some of these agents are being developed for vaginal application, and for rectal use by those engaging in anal sex. (wikipedia.org)
  • Most microbicide research has been focused on products for vaginal use, yet the risk of becoming infected with HIV from unprotected anal sex may be 20 times greater than unprotected vaginal sex, in part because the rectal lining is only one-cell thick compared to the vagina's multiple layers. (mtnstopshiv.org)
  • The study results advance efforts to develop a rectal microbicide that researchers hope can help curb the high rate of HIV infections attributed to unprotected anal sex. (mtnstopshiv.org)
  • Rectal microbicides are also being studied, as douches, lubes and inserts - products that may conform to behaviors already practiced around the time of anal sex. (mtnstopshiv.org)
  • These medications also lower the amount of the virus in other bodily fluids such as semen, anal or rectal secretions, and vaginal fluids. (healthline.com)
  • full citation needed] Detergent and surfactant microbicides such as nonoxynol-9, sodium dodecyl sulfate and Savvy (1.0% C31G), act by disrupting the viral envelope, capsid or lipid membrane of microorganisms. (wikipedia.org)
  • 7. Why do men and women need rectal microbicides? (mtnstopshiv.org)
  • The most common active ingredient of spermicides is nonoxynol-9 . (wikidoc.org)
  • Use a latex condom without nonoxynol-9 if you or your sex partner has HIV/AIDS, multiple sex partners, or other HIV risk factors. (nih.gov)
  • According to data presented at the Association of Nurses in AIDS Care 2019 Conference, half the gay and bisexual black men in the Deep South have used an enema - or "rectal douche" as it's called in the community - although what they are using to douche is unclear. (medscape.com)
  • In addition, Baker said he counsels his patients on how to care for the delicate rectal mucosa, which is only one layer of cells thick, unlike the vaginal lining, which is multiple layers thick. (medscape.com)
  • MTN-007 was a Phase I study involving 65 HIV-negative men and women designed to determine whether a reformulated version of tenofovir gel is safe and acceptable as a potential rectal microbicide. (mtnstopshiv.org)