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GnRHGonadotrophinPregnylPituitaryEquine chorionic gonadotropinExogenousFollicleGrowing embryoMenopausal gonadotropinSupplementationAntibodiesGlycoproteinUrinary and recombinantReactivityVitroEmbryo transferStimulationPregnancyPregnant mare serumSerumOocyteInfertilityLutealTestosteroneInjectionGrowth HormoneLuteinizingPeptidePlacentaToxoidTriggerGlycoproteinsOvarian hyperstimulationOvulationDosesVaccinesClinicalReproductive hormonesPreparationsMechanismsBetaUrineGranulosa cellsEmbryos

GnRH11

• Controlled ovarian hyperstimulation was achieved by administering 150 IU of recombinant FSH follitropin beta (Puregon, NV Organon, Oss, Netherlands) combined with GnRH antagonist cetrorelix acetate (Cetrotide, Asta Medica, Frankfurt, Germany). (hindawi.com)
• Luteinizing hormone (LH) is a glycoprotein gonadotropin secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GnRH), which is released by the hypothalamus. (medscape.com)
• Moreover, in the pivotal clinical trial demonstrating the efficacy and safety of Bemfola ® , pituitary suppression was performed using gonadotropin-releasing hormone (GnRH) agonists, whereas an increasing number of ART cycles are currently being performed using GnRH-antagonists. (jri.ir)
• The hypothalamus secretes gonadotropin-releasing hormone (GnRH) in pulsatile bursts every hour. (formularywatch.com)
• It included consecutive patients aged 18-41 years who fulfilled Bologna criteria for POR undergoing intra-ovarian androgen priming and ultra-long down-regulation with a gonadotropin-releasing hormone agonist (GnRHa), followed by stimulation with gonadotropins and GnRH antagonist co-treatment for IVF (n=30). (hoperesearchcenter.vn)
• Is earlier administration of human chorionic gonadotropin (hCG) associated with the probability of pregnancy in cycles stimulated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone (GnRH) antagonists? (druglib.com)
• Incidence and severity of ovarian hyperstimulation syndrome (OHSS) in high responders after gonadotropin-releasing hormone (GnRH) agonist trigger in "freeze-all" approach. (ivi-rmainnovation.com)
• The use of agonistic or antagonistic gonadotropin-releasing hormone (GnRH) protocols in stimulated IVF/intracytoplasmic sperm injection (ICSI) cycles cause disruptions to the luteal phase, leading to inadequate development of the endometrium and asynchrony between endometrial receptiveness and embryo transfer. (biomedcentral.com)
• Treatment of the genetic mother: The genetic mother will be treated with a period of long downregulation with the gonadotropin releasing hormone (GnRH) analog ( Leuprolide or buserelin) for up to 2 weeks after which the serum levels of luteinizing hormone (LH), progesterone and estradiol are measured. (universalhunt.com)
• Secondary hypogonadism is failure of the hypothalamus to produce gonadotropin-releasing hormone (GnRH), as in idiopathic hypogonadotropic hypogonadism, or of the pituitary gland to produce enough FSH and LH. (msdmanuals.com)
• Human chorionic gonadotrophin (hCG, Follutein, Solvay Veterinary Inc., Princeton, NJ) has LH-like activity and can be used as well as GnRH to induce ovulation. (ubbcluj.ro)

Gonadotrophin3

• Levels of the epidermal growth factor-like peptide amphiregulin in follicular fluid reflect the mode of triggering ovulation: a comparison between gonadotrophin-releasing hormone agonist and urinary human chorionic gonadotrophin. (druglib.com)
• Effect on fertility of human chorionic gonadotrophin and uterine lavage with oxytocin performed after mating in Arabian barren mares. (druglib.com)
• Product NameHuman Chorionic Gonadotrophin for InjectionSwissHCG is pharma grade HCG from SwitzerlandCompositionA preparation of Chorionic Gonadotrophin, which is a sterile lyophilized form after adding appropriate excipient.The titer is 80%-125% of the labelled amount.IndicationA. (wjxmysw.com)

Pregnyl1

• After 8 days of stimulation, 10000 IU of human chorionic gonadotropin (Pregnyl, NV Organon, Oss, Netherlands) was administered for oocyte maturation. (hindawi.com)

Pituitary4

• The same pituitary cells also secrete FSH, another gonadotropin. (medscape.com)
• In response to the secretions, the anterior pituitary secretes gonadotropins, follicle-stimulating hormone (FSH), and luteinizing hormone (LH). (formularywatch.com)
• FSH is a protein made by the human pituitary gland and it has an effect on the ovary to push more follicles to develop. (pacificfertility.ca)
• Long-term gonadotropin dysfunction should be supplemented with testosterone.C. Female anovulatory infertility induced by pituitary gonadotropin deficiency. (wjxmysw.com)

Equine chorionic gonadotropin3

• In veterinary medicine, equine chorionic gonadotropin (eCG) extracted from pregnant mare serum is used instead on a variety of mammals, sometimes eliciting an immune response in non-horse species. (wikipedia.org)
• Progesterone concentrations, exogenous equine chorionic gonadotropin, and timing of prostaglandin F(2alpha) treatment affect fertility in postpuberal Nelore heifers. (druglib.com)
• The effect of addition of equine chorionic gonadotropin to a progesterone-based estrous synchronization protocol in buffaloes (Bubalus bubalis) under tropical conditions. (druglib.com)

Exogenous3

• A number of tests have been proposed and evaluated that may be used to prognosticate ovarian responsiveness to exogenous gonadotropin stimulation, quality of the oocytes, subsequent implantation and pregnancy rates (PR) (6-9). (ijfs.ir)
• Thus, exogenous rLH administration can be calibrated independently of recombinant follicle-stimulating hormone (rFSH). (biomedcentral.com)
• and clinical monitoring for hyperresponse in those treated with exogenous gonadotropins for infertility. (medscape.com)

Follicle9

• Common side effects of preparations containing FSH and LH are: Mild bloating Pain, swelling, or irritation injection site Rash at injection site or other part of body Stomach pain or pelvic pain Preparations of follicle-stimulating hormone (FSH) mainly include those derived from the urine of menopausal women, as well as recombinant preparations. (wikipedia.org)
• The package insert for Puregon states that structural analysis shows that the amino acid sequence of follitropin beta is identical to that of natural human follicle stimulating hormone (hFSH). (wikipedia.org)
• Recombinant human follicle-stimulating hormone (r-hFSH) has been used as part of assisted reproductive technology (ART) since the 1990s. (jri.ir)
• With the aim to generate biologically active 15N-labeled glycohormones for conformational studies focused on the unravelling of the NMR structures in solution, the P. pastoris strains GS115 and X-33 were explored for the expression of human chorionic gonadotropin (phCG) and human follicle-stimulating hormone (phFSH). (iisc.ac.in)
• Pichia pastoris GS115;Pichia pastoris X-33;Human chorionic gonadotropin;Human follicle stimulating hormone;Glycosylation;Hypermannosylation;15N-Labeling. (iisc.ac.in)
• Follicle-stimulating hormone administered at the time of human chorionic gonadotropin trigger improves oocyte developmental competence in in vitro fertilization cycles: a randomized, double-blind, placebo-controlled trial. (druglib.com)
• The effect of cetrorelix vs. ganirelix on pregnancy outcome using minimal gonadotropin stimulation in women with elevated day 3 serum follicle stimulating hormone levels. (druglib.com)
• Recombinant follicle stimulating hormone(FSH) 150 IU or 225 IU daily is given and the patient is followed up after 5 days of stimulation and the stimulation is continued until two leading follicles reach at least 18 mm in mean diameter and serum estradiol levels are commensurate with the number and size of follicles. (universalhunt.com)
• Once the lead follicle/s measure at least 16 to 18 millimeters in diameter, you will be instructed to take an injection of human chorionic gonadotropin (hCG), which triggers ovulation. (ubbcluj.ro)

Growing embryo1

• Human Chorionic Gonadotropin is produced from the cells that surround a growing embryo, which goes on to form the placenta. (prospecbio.com)

Menopausal gonadotropin1

• To help stimulate the making of sperm in the testis, recombinant FSH ( rFSH ) or human menopausal gonadotropin ( hMG ) may be used . (maledoc.com)

Supplementation3

• A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study. (druglib.com)
• The benefit of human chorionic gonadotropin supplementation throughout the secretory phase of frozen-thawed embryo transfer cycles. (druglib.com)
• Although luteal human chorionic gonadotropin (hCG) supplementation has proven to be an effective way to overcome luteal phase defects, this treatment is frequently associated with an increased risk of ovarian hyperstimulation syndrome (OHSS) [ 7 ], so the current most widely used form of LPS is progesterone (P). (biomedcentral.com)

Antibodies1

• Gonadotropin-releasing hormone/human chorionic gonadotropin beta based recombinant antibodies and vaccines. (harvard.edu)

Glycoprotein3

• Human Chorionic Gonadotropin is a glycoprotein that is composed of 237 amino acids and has a molecular mass of 36.7 kDa, approximately 14.5 ahCG, and 22.2kDa βhCG. (prospecbio.com)
• Human thyrotropin (TSH), luteotropin (LH), follitropin (FSH), and chorionic gonadotropin are members of the heterodimeric glycoprotein hormone family. (jci.org)
• Two novel human glycoprotein hormonelike genes, α2 (A2) and β5 (B5), recently have been identified. (jci.org)

Urinary and recombinant2

• Results show the activity of hCG (both urinary and recombinant) on glycemia and leptins levels in experimental animals in different formulations, but specifically when administered intrarectal. (b12nearme.com)
• Most often, OHSS occurs There are urinary and recombinant HCG preparations. (ubbcluj.ro)

Reactivity2

• 118-20C-CR6077SP Clonality: Polyclonal Isotype: IgG Host: Rabbit Species Reactivity: Human Purity/Purification: Caprylic Acid Ammonium Sulfate Precipitation Purified Storage Buffer: (Preservative) 0.03% Proclin 300. (bioscience-explained.org)
• 15-930-100-TTG Reactivity: Human Tested Applications: ELISA Recommended dilutions: Optimal dilutions/concentrations should be determined by the end user. (bioscience-explained.org)

Vitro5

• A comparison of outcomes from in vitro fertilization cycles stimulated with either recombinant luteinizing hormone (LH) or human chorionic gonadotropin acting as an LH analogue delivered as human menopausal gonadotropins, in subjects with good or poor ovarian reserve: A retrospective analysis. (medscape.com)
• Comparison of serum and follicular fluid hormone levels with recombinant and urinary human chorionic gonadotropin during in vitro fertilization. (druglib.com)
• The objective of this study was to determine the gene expression profiles of the androgen/androgen receptor (AR) and anti-Müllerian hormone (AMH)/ Sry-related high-mobility group box 9 (SOX9) pathways in granulosa-luteal cells from patients undergoing standard in vitro fertilization (IVF) with or without recombinant luteinizing hormone (rLH) therapy. (biomedcentral.com)
• RÉSUMÉ La présente étude menée en Turquie a évalué l'impact de la loi rendant obligatoire le transfert d'un embryon unique en fonction de l'âge et de l'augmentation consécutive des transferts d'embryons congelés- décongelés sur l'issue de la grossesse des patientes bénéficiant d'une fécondation in vitro. (who.int)
• Le transfert d'un embryon unique, le transfert d'embryons congelés-décongelés et le transfert de deux embryons ont été réalisés chez 5632 patientes après l'entrée en vigueur de la loi, tandis que l'approche traditionnelle par fécondation in vitro et par transferts d'embryons congelés-décongelés a été utilisée chez 6029 patientes avant le vote de cette loi. (who.int)

Embryo transfer1

• Cryopreserved-thawed human embryo transfer: spontaneous natural cycle is superior to human chorionic gonadotropin-induced natural cycle. (druglib.com)

Stimulation1

• The effect of gonadotropin withdrawal and stimulation with human chorionic gonadotropin on intratesticular androstenedione and DHEA in normal men. (druglib.com)

Pregnancy4

• Initial results demonstrates similar pregnancy rates as daily recombinant FSH injections. (wikipedia.org)
• hCG, Human Chorionic Gonadotropin is the hormone that is detected on home pregnancy tests in the early stages of pregnancy. (prospecbio.com)
• If pregnancy occurs, human chorionic gonadotropin (hCG) from the placenta prevents regression of the corpus luteum and maintains steroid (progesterone and estrogen) production to sustain the pregnancy. (formularywatch.com)
• Human chorionic gonadotropin (hCG) is known as the pregnancy hormone because its levels increase once a pregnancy is established. (pacificfertility.ca)

Pregnant mare serum1

• MATERIALS AND METHODS: A COH mouse model was established via an intraperitoneal injection of 0.4 IU/g pregnant mare serum gonadotropin (PMSG) and 1 IU/g human chorionic gonadotropin (HCG). (bvsalud.org)

Serum4

• A prospective, randomized, controlled study to compare two doses of recombinant human chorionic gonadotropin in serum and follicular fluid in woman with high body mass index. (druglib.com)
• Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin. (druglib.com)
• Following gonadotropin treatment, serum adiponectin levels decrease as a result of the negative effect of high estradiol levels on adiponectin production. (b12nearme.com)
• Conversely, serum adiponectin levels increase following human chorionic gonadotropin treatment . (b12nearme.com)

Oocyte3

• The effect of low dose human chorionic gonadotropin on follicular response and oocyte maturation in PCOS patients undergoing IVF cycles: a randomized clinical trial of efficacy and safety. (druglib.com)
• 1,500 IU human chorionic gonadotropin administered at oocyte retrieval rescues the luteal phase when gonadotropin-releasing hormone agonist is used for ovulation induction: a prospective, randomized, controlled study. (druglib.com)
• Variations in L-selectin ligand expression in the luteal-phase endometrium after final oocyte maturation with human chorionic gonadotropin compared with a gonadotropin-releasing hormone agonist. (druglib.com)

Infertility1

• There are numerous classes of medications available to assist women who have been diagnosed with infertility.Agents that are used in the treatment of infertility include: clomiphene citrate, aromatase inhibitors, gonadotropins, chorionic gonadotropins, gonadotropin-releasing hormone, gonadotropin-releasing hormone agonists, gonadotropin-releasing hormone antagonists, follitropins, and other miscellaneous agents. (formularywatch.com)

Luteal1

• Low-dose human chorionic gonadotropin versus estradiol/progesterone luteal phase support in gonadotropin-releasing hormone agonist-triggered assisted reproductive technique cycles: understanding a new approach. (druglib.com)

Testosterone3

• Dose-dependent increase in intratesticular testosterone by very low-dose human chorionic gonadotropin in normal men with experimental gonadotropin deficiency. (druglib.com)
• Treatment varies with etiology but typically includes gonadotropin-releasing hormone, gonadotropin, or testosterone replacement. (msdmanuals.com)
• Bob recently asked about using hCG (human chorionic gonadotropin) rather than clomiphene to increase testosterone. (maledoc.com)

Injection2

• One study reported that users of the purified urinary FSH preparation Bravelle experienced less injection site pain compared to the recombinant preparation Follistim. (wikipedia.org)
• Generic lutropin alfa for injection Brands Luveris Human chorionic gonadotropin (hCG) can be recovered from the urine of pregnant women or be produced from recombinant DNA. (wikipedia.org)

Growth Hormone1

• Somatrogon is a long-acting protein known as a recombinant human growth hormone (rhGH), obtained through recombinant DNA technology. (pfizerpro.in)

Luteinizing1

• Luteinizing hormone (LH) plays a vital role in induced ovulation and controlled ovarian hyperstimulation in human assisted reproduction. (itmedicalteam.pl)

Peptide1

• 3A2 is an antibody raised against human chorionic gonadotropin and recognizes a linear epitope on the C-terminal peptide of the human chorionic gonadotropin ÉÇ-subunit. (antibodypedia.com)

Placenta1

• Human Chorionic Gonadotropin Production hCG is produced by the human placenta, by the syncytiotrophoblast. (prospecbio.com)

Toxoid1

• Published research shows that by 1976 WHO researchers had conjugated tetanus toxoid (TT) with human chorionic gonadotropin (hCG) producing a "birth-control" vaccine. (weeksmd.com)

Trigger1

• Human chorionic gonadotropin trigger is given 34 to 36 hrs before the intended time of oocytes recovery. (universalhunt.com)

Glycoproteins2

• Recombinant A2/B5 heterodimeric glycoproteins, purified using cation exchange and size fractionation chromatography, activated human TSH receptors, but not LH and FSH receptors, and showed high affinity to TSH receptors in a radioligand receptor assay. (jci.org)
• The methylotrophic yeast Pichia pastoris is widely used for the production of recombinant glycoproteins. (iisc.ac.in)

Ovarian hyperstimulation1

• Gonadotropin preparations are drugs that mimic the physiological effects of gonadotropins, used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. (wikipedia.org)

Ovulation1

• Human granulosa cells were used to test the hypothesis that exposure to a phthalate mixture (PHTmix) disrupts progesterone (P4)/progesterone receptor (PGR) signaling, which is a crucial pathway for ovulation. (bvsalud.org)

Doses1

• Evaluation of endocrine testing of Leydig cell function using extractive and recombinant human chorionic gonadotropin and different doses of recombinant human LH in normal men. (druglib.com)

Vaccines1

• Currently WHO researchers are working on more potent anti-fertility vaccines using recombinant DNA. (weeksmd.com)

Clinical1

• Human umbilical cord platelet-rich plasma to treat endometrial pathologies: methodology, composition and pre-clinical models. (ivi-rmainnovation.com)

Reproductive hormones1

• One way to take over the pituitary's production of its reproductive hormones is to use human chorionic gonadotropin ( hCG ), which looks like LH to the body. (maledoc.com)

Preparations1

• The recombinant preparations are more pure and more easily administered, but they are more expensive. (wikipedia.org)

Mechanisms1

• Perrett RM, McArdle CA. Molecular Mechanisms of Gonadotropin-Releasing Hormone Signaling: Integrating Cyclic Nucleotides into the Network. (medscape.com)

Beta1

• In adolescents and women with suspected FHA, we recommend obtaining the following screening laboratory tests: beta-human chorionic gonadotropin, complete blood count, electrolytes, glucose, bicarbonate, blood urea nitrogen, creatinine, liver panel, and (when appropriate) sedimentation rate and/or C-reactive protein levels. (medscape.com)

Urine3

• medical citation needed] For example, the so-called menotropins consist of LH and FSH extracted from human urine from menopausal women. (wikipedia.org)
• medical citation needed] hMG (human Menopausal Gonadotrophins), FSH and LH prepared from human urine collected from postmenopausal women. (wikipedia.org)
• Like other gonadotropins, it can be extracted for the urine of a pregnant person or produced from cultures of genetically modified cells using DNA technology. (prospecbio.com)

Granulosa cells1

• These findings suggest that phthalate mixture exposure inhibits P4/PGR signaling in human granulosa cells via decreased steroidogenesis, cAMP levels, and protein kinase A activity. (bvsalud.org)

Embryos2

• Furthermore, due to ethical and legal concerns, very limited techniques can be applied to human embryos to validate some of significant conclusions drawn from descriptive studies regarding human embryonic development. (nature.com)
• 11 ] developed the first time-lapse system for studying morphokinetics in human embryos. (ecerm.org)