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Recombinant ProteinsRecombinant Fusion ProteinsDNA, RecombinantMolecular Sequence DataAmino Acid SequenceCloning, MolecularBase SequenceGenetic VectorsEscherichia coliVaccines, SyntheticRecombination, GeneticCell LineBaculoviridaePlasmidsKineticsGene ExpressionSequence Homology, Amino AcidDNA, ComplementaryEnzyme-Linked Immunosorbent AssaySpodopteraPichiaProtein BindingMice, Inbred BALB CVaccinia virusCells, CulturedCricetinaeTransfectionElectrophoresis, Polyacrylamide GelSubstrate SpecificityDNA PrimersAdenoviridaeBinding SitesBlotting, WesternBacterial ProteinsSequence AlignmentViral VaccinesMutationAntibodies, ViralDependovirusProtein Structure, TertiaryCHO CellsViral ProteinsMutagenesis, Site-DirectedAntibodies, MonoclonalPeptide FragmentsImmunizationRNA, MessengerImmunoglobulin GGenetic EngineeringErythropoietinInsectsGlycosylationRabbitsMice, Inbred C57BLDose-Response Relationship, DrugMolecular WeightVirus ReplicationCattleEpitopesGene Transfer TechniquesViral Envelope ProteinsGenetic TherapyProtein EngineeringProtein ConformationPolymerase Chain ReactionCercopithecus aethiopsInterferon-gammaGlycoproteinsTime FactorsDNAGenes, ViralAntigens, BacterialSequence Analysis, DNAProtozoan ProteinsTumor Cells, CulturedAntibodiesGenes, BacterialCarrier ProteinsDNA, ViralCircular DichroismAntigens, ViralRestriction MappingVaccinationAntigens, ProtozoanMothsModels, MolecularImmunoblottingHeLa CellsAntibodies, BacterialChromatography, AffinityEnzyme StabilityPeptidesSolubilityMembrane GlycoproteinsTransduction, GeneticNeutralization TestsAntibodies, ProtozoanStructure-Activity RelationshipAntibody SpecificityBacterial Vaccines
ProteinsColiAntibodyInterferonSpeciesPurityInsect CellsEnzymeBeta proteinSequenceYeastBDNFVitroInfluenzaConcentrationELISAMonomerSerumDeficiencySoluble1985CytotoxicGrowthCatalogProtein productionTherapeuticFormCellsBoneAffinitySearchMolecular massAmino acid proteinGenesHerpesExperimentsCCL4ResearchCell
Proteins14
Coli5
  • An E. coli strain that carries a plasmid encoding the cloned human histone H4 gene, HIST2H4. (neb.com)
  • Recombinant KISS1 protein was expressed in E.coli and purified by using conventional chromatography techniques. (novusbio.com)
  • POLR2K Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 81 amino acids (1-58 a.a) and having a molecular mass of 9.4kDa. (prospecbio.com)
  • IL21 Protein LS-G3653 is a Recombinant Human IL21 produced in E. coli. (lsbio.com)
  • LP3 is fully equipped for recombinant protein production in E. coli and insect cells (BEVS) and protein purification using state of the art chromatography systems. (lu.se)
Antibody3
  • This IL-5 protein is useful as a standard for a human IL-5 sandwich ELISA, using unlabeled JES1-39D10 antibody (catalog #500902) for capture and biotinylated JES1-5A10 antibody (catalog #501002) for detection. (biolegend.com)
  • Human Anti-HSV gD Recombinant Antibody (clone HuFd138-80) - 1mg - 1 kit is backordered and will ship as soon as it is back in stock. (dnamethsoc.com)
  • Here, we have used a recombinant scFv antibody microarray in an attempt to classify sera derived from pancreatic adenocarcinoma patients vs. healthy subjects. (lu.se)
Interferon17
  • Neurological effects of recombinant human interferon. (bmj.com)
  • Ten women with advanced locally recurrent breast cancer who had failed to respond to radiation and hormonal and cytotoxic agents were given up to 12 weeks of recombinant leucocyte interferon 20 X 10(6) U/m2 daily or 50 X 10(6) U/m2 three times a week. (bmj.com)
  • The IFNA2 (interferon alpha 2) gene is mapped to human chromosome 9p21.3. (sigmaaldrich.com)
  • Interferon α 2A human has been used to check its antiviral action against chikungunya virus. (sigmaaldrich.com)
  • Recombinant human interferon protein (IFN-y) is a bioactive protein primarily used for cell culture applications in many diagnostic laboratories. (clickpress.com)
  • The status of recombinant human interferon protein is strictly regulated as it require strict temperature control, which is around -70°C or below for retaining full action activity. (clickpress.com)
  • Recombinant human interferon protein is mostly available in beta and alpha form, though other forms have started emerging in the market. (clickpress.com)
  • Recombinant human interferon protein is principally studied on the protein production, it is probably going to strike the intensive research and development sector. (clickpress.com)
  • The adoption of recombinant human interferon protein started with the advancement in the field of molecular biology. (clickpress.com)
  • Tentatively, the global recombinant human interferon protein market can be segmented on the basis of type, end user and geography. (clickpress.com)
  • The global market for recombinant human interferon protein is expected to witness steady growth over the forecast period due to rise of molecular biology in most of the disease applications. (clickpress.com)
  • Geographically, the global recombinant human interferon protein market is segmented into North America, Latin America, Europe, CIS & Russia, Asia-Pacific excluding Japan (APEJ), Japan and the Middle East and Africa (MEA). (clickpress.com)
  • North America is expected to be the dominant regional market for recombinant human interferon protein owing to increasing number of research activities in the region. (clickpress.com)
  • The recombinant human interferon protein market in Asia Pacific excluding Japan is expected to grow at a significant CAGR due to product development and expansion by key players. (clickpress.com)
  • Europe is expected to hold a large share in the global recombinant human interferon protein market throughout the forecast period due to its quality healthcare facilities and modern outlook for recombinant human Interferon protein. (clickpress.com)
  • The global market for recombinant human interferon protein is highly fragmented. (clickpress.com)
  • Examples of some of the key players operating in the global recombinant human interferon protein market are Merck KGaA, Abcam plc, R&D Systems, Thermo Fisher Scientific, BioLegend, Invitrogen, OriGene, and Biorbyt, among others. (clickpress.com)
Species1
  • Human and murine TNF-α demonstrate significant cross-species reactivity. (peprotech.com)
Purity1
  • The purity of Human ACE2 (18-615) Recombinant Protein (hFc-Tag) was determined by densitometry after SDS-PAGE of 1 μg of protein, followed by staining with Coomassie Blue. (cellsignal.com)
Insect Cells1
Enzyme3
  • We produced the recombinant enzyme in mammalian cells, purified it, and measured the inhibition constants for paraoxon and surrogates of VX, sarin and tabun. (rcsb.org)
  • Enhanze™ technology is a proprietary drug delivery platform using Halozyme's first approved enzyme, recombinant human hyaluronidase or rHuPH20. (prnewswire.com)
  • The Recombinant Human Lysyl Oxidase Homolog 2 Protein has been validated for the following applications: Enzyme Activity. (fishersci.com)
Beta protein1
  • The Human CCL4/MIP-1 beta protein can be used in cell culture, as a CCL4/MIP-1 beta ELISA Standard, and as a Western Blot Control. (immunochemistry.com)
Sequence2
  • Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. (peprotech.com)
  • Mature human CCL4 shares 77% and 80% aa sequence identity with mouse and rat CCL4, respectively. (rndsystems.com)
Yeast2
  • Human CCL4 Recombinant Protein is purified chemokine ligand 4 (CCL4, MIP-1 beta) produced in yeast. (immunochemistry.com)
  • Together with former clinical results this underlines the experience that type I and type III reactions against putative yeast contaminants apparently play no major role after immunization with recombinant hepatitis B vaccines. (karger.com)
BDNF3
  • BDNF acts as a survival factor for human embryonic stem cells when plated on either feeder cells or Corning® Matrigel® (Pyle et al. (stemcell.com)
  • BDNF, together with glial cell line-derived neurotrophic factor (GDNF) and other supplements, is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into neurons (Brafman). (stemcell.com)
  • A) The biological activity of Human Recombinant BDNF was tested by its ability to promote the proliferation of a neuroblastoma cell line stably expressing TrkB (BR6). (stemcell.com)
Vitro2
  • We routinely use recombinant human TNF-α in co-incubation with HT29 cells to characterization in vitro of anti-inflammatory probiotic properties of potential candidate strains used IL-8 as readout. (peprotech.com)
  • In vitro and in vivo experiments will be conducted to investigate how recombinant transferrin interacts with cellular receptors, regulates iron uptake, and influences cellular proliferation. (prospecbio.com)
Influenza2
  • What are the risks from inactivated or recombinant influenza vaccine? (medlineplus.gov)
  • Researchers are conducting the first-in-human trial of a universal influenza vaccine candidate, the National Institutes of Health (NIH) announced April 3. (medscape.com)
Concentration1
  • Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. (rndsystems.com)
ELISA1
  • In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (rndsystems.com)
Monomer1
  • HumanKine IFN-α 2A, expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 16 kDa. (sigmaaldrich.com)
Serum3
  • Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. (rndsystems.com)
  • Exbumin ® is a recombinant human serum albumin that is manufactured using good manufacturing practices at an ISO9001:2015 certified facility in Kansas, USA. (invitria.com)
  • Based on analysis of non-fractionated, directly labeled, whole human serum proteomes we have identified a protein signature based on 19 non-redundant analytes, that discriminates between cancer patients and healthy subjects. (lu.se)
Deficiency4
  • Clinical trials and studies involving individuals with iron-related disorders, such as iron-deficiency anemia, will be conducted to evaluate the efficacy and safety of recombinant transferrin supplementation. (prospecbio.com)
  • HAE is a rare, severely debilitating, life-threatening genetic disorder caused by a deficiency of C1 inhibitor, a human plasma protein. (prnewswire.com)
  • In the United States, recombinant human growth hormone is used in the pediatric population to treat short stature due to growth hormone deficiency (including idiopathic [of unknown cause] growth hormone deficiency), Turner syndrome, Noonan syndrome, Prader-Willi syndrome, short stature homeobox-containing gene (SHOX) deficiency, chronic renal insufficiency, idiopathic short stature and children small for gestational age. (fda.gov)
  • The risk of death was reported to be increased when doses of recombinant growth hormone that are higher than what is normally prescribed for pediatric growth hormone deficiency were used. (fda.gov)
Soluble1
  • Recombinant Human TNF-α is a soluble 157 amino acid protein (17.4 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein. (peprotech.com)
19853
  • The study population was based on a mandatory registry of patients in France who received recombinant human growth hormone treatment during childhood between 1985 and 1996 and whose vital status and cause of death was determined through September 2009. (fda.gov)
  • 1-3 This study was based on a mandatory registry of patients in France treated with recombinant growth hormone during childhood between 1985 and 1996. (fda.gov)
  • The commercial introduction of recombinant human growth hormone (rhGH) in 1985 dramatically changed the field of therapy for growth hormone (GH). (medscape.com)
Cytotoxic1
  • Recombinant human IFN-γ induced cytotoxic effect on HT-29 cells in a dose-dependent manner. (biolegend.com)
Growth11
  • At this time, FDA recommends that patients continue their recombinant human growth hormone treatment as prescribed by their healthcare provider. (fda.gov)
  • Recombinant human growth hormone is a protein that is manufactured to be nearly identical to the main form of the naturally occurring human growth hormone. (fda.gov)
  • 1-3 It was designed to assess the long-term mortality of patients treated with recombinant human growth hormone during childhood. (fda.gov)
  • Do not stop taking recombinant human growth hormone without talking to your healthcare professional. (fda.gov)
  • Discuss any questions or concerns about recombinant human growth hormone with your healthcare professional. (fda.gov)
  • At this time, FDA believes the benefits of recombinant growth hormone continue to outweigh its potential risks. (fda.gov)
  • If you prescribe recombinant human growth hormone, follow the recommended indications and doses in the product labels. (fda.gov)
  • FDA is aware of the results of a long-term epidemiological study called SAGhE (Santé Adulte GH Enfant), which was designed to assess the long-term mortality of patients treated with recombinant human growth hormone during childhood. (fda.gov)
  • The investigators report a 30% increased risk of death with recombinant human growth hormone therapy compared to the general population, with 93 observed deaths in the treated group versus 70 expected deaths in the general population in France. (fda.gov)
  • The trends supporting the entire recombinant therapeutics are expected to influence the growth of the market. (clickpress.com)
  • Achievement of final adult height consistent with a child's genetic potential remains the primary therapeutic endpoint for recombinanat human growth hormone (rhGH) therapy in the pediatric population. (medscape.com)
Catalog1
  • The following product was used in this experiment: Human MAP4K5 (KHS1), GST Tag Recombinant Protein from Thermo Fisher Scientific, catalog # PV3682. (thermofisher.com)
Protein production1
  • As such, we provide services and make equipment available in the areas of recombinant protein production, crystallisation, biophysical characterization, and structure determination. (lu.se)
Therapeutic2
  • Its recombinant form, produced through advanced biotechnological methods, offers several advantages for therapeutic and research purposes. (prospecbio.com)
  • These investigations may provide insights into the use of recombinant transferrin as a therapeutic agent in various clinical settings. (prospecbio.com)
Form1
  • Recombinant human parathyroid hormone, sold under the brand names Preotact and Natpara, is an artificially manufactured form of the parathyroid hormone used to treat hypoparathyroidism. (wikipedia.org)
Cells8
  • Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses. (peprotech.com)
  • Recombinant Human Transferrin produced in CHO cells is a glycosylated, polypeptide chain containing having a molecular mass of 76 kDa. (prospecbio.com)
  • Per researcher's feedback, the protein is biologically active as determined by the dose-dependent stimulation of the proliferation of human μmbilical vein endothelial cells (HUVEC) in the presence of human VEGF165. (biovision.com)
  • Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CCR5. (rndsystems.com)
  • Production in human HEK 293 cells offers authentic glycosylation. (sigmaaldrich.com)
  • Tong Q, Chang-jian L, Feng R, Li H, Le Z, Lei L. Experimental study of recombinant aukaryotic expression vector of human eNOS in ECV304 cells. (smw.ch)
  • Determined by its ability to stimulate the proliferation of human ANBL-6 cells. (lsbio.com)
  • Modification of existing genes in living animal and human cells is enabled by engineered nucleases such as meganucleases, zinc finger nucleases, transcription activator-like effector-based nucleases, and the CRISPR-Cas system. (cdc.gov)
Bone1
  • Evaluate clinically and radiographically the conditions of bone density around the experimental bioactive implants that are covered with Bone Morphogenetic Protein recombinant human type-2 (rhBMP-2) (IE) and to compare it to that obtained whit rough- surface implants (IC). (bvsalud.org)
Affinity1
  • Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. (origene.com)
Search1
  • Aiming at identifying an alternative human protein bioscavenger, we looked for an original scaffold candidate by virtual screening of the Protein Data Bank for functional similarity using the "Surfing the Molecules" software (sumo-pbil.ibcp.fr) and a search model based on the BChE active site topology. (rcsb.org)
Molecular mass1
  • The 144 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 16,907 Da. (biolegend.com)
Amino acid protein1
Genes1
  • This study sought to (1) identify gene expression signatures in the mouse lungs following pharyngeal aspiration of well-dispersed MWCNT and (2) determine if these genes were associated with human lung cancer risk and progression. (cdc.gov)
Herpes1
  • By preventing shingles, Shingles (also called herpes zoster, or just zoster) recombinant shingles vaccine also protects against PHN is a painful skin rash, usual y with blisters. (cdc.gov)
Experiments1
  • Forty two years ago, in February 1975, the Asilomar Conference on Recombinant DNA [1] established guiding principles for safe conduct of experiments utilizing recombinant DNA technology, which facilitated the creation of a biotechnology industry in the 1980s. (cdc.gov)
CCL43
  • Bulk Order Inquiry for Recombinant Human CCL4 ------- (please add any order requirements, including desired quantity, timing, etc. (immunochemistry.com)
  • The first two N-terminal amino acids can be cleaved from human CCL4 by CD26/DPPIV (10, 11). (rndsystems.com)
  • In humans, the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a coreceptor (2). (rndsystems.com)
Research7
  • This product is for research use only and is not approved for use in humans or in clinical diagnosis. (novusbio.com)
  • The primary objective of this research is to elucidate the essential role of transferrin in iron homeostasis and its significance for human health. (prospecbio.com)
  • The third objective is to explore the broader implications of human recombinant transferrin in biomedicine and research. (prospecbio.com)
  • Understanding the multifaceted properties of recombinant transferrin may open new avenues for innovative approaches in various medical specialties and scientific research. (prospecbio.com)
  • By delving into the diverse functions of human recombinant transferrin, this research aims to expand our understanding of its physiological roles and clinical applications. (prospecbio.com)
  • Nicolau Cunha of the University of Brasilia, together with other scientists, reports the expression and stable accumulation of human coagulation factor IX (hFIX) in genetically engineered soybean seeds, published in the December 2010 issue of the Transgenic Research journal. (isaaa.org)
  • These principles of biosafety laid the foundation for the NIH Guidelines for Research involving Recombinant or Synthetic Nucleic Acid Molecules, the primary biosafety guidelines in use today [2]. (cdc.gov)
Cell2