• Although the mechanism of primers amplifying env (437 bp and 1,700 bp) and env /LTR immunopathogenesis is unclear, viral envelope proteins (725 bp) are listed in Figure 2. (cdc.gov)
  • DNA sequences that form the coding region for the viral envelope (env) proteins in retroviruses. (lookformedical.com)
  • The products are usually synthesized as protein precursors or POLYPROTEINS, which are then cleaved by viral proteases to yield the final products. (lookformedical.com)
  • ChAdOx1-HPV is a recombinant replication-incompetent chimpanzee-derived adenovirus (ChAdY25) viral vector. (biosafety.be)
  • Gp120-alum boosting of a Gag-Pol-Env DNA/MVA AIDS vaccine: poorer control of a pathogenic viral challenge. (ucdenver.edu)
  • Elucidating these mechanisms and identifying which cellular factors are exploited by the retroviruses and which hinder their life cycle, will certainly lead to the discovery of new ways to inhibit viral replication and to improve retroviral vectors for gene transfer. (biomedcentral.com)
  • The life cycle of retroviruses is arbitrarily divided into two distinct phases: the early phase refers to the steps of infection from cell binding to the integration of the viral cDNA into the cell genome, whereas the late phase begins with the expression of viral genes and continues through to the release and maturation of progeny virions (see Figure 1 for a schematic view of the retroviral life cycle). (biomedcentral.com)
  • Evaluation of efficacy of Salmonella Dublin-Typhimurium vaccine, double gene deleted avirulent live culture in calves. (biosafety.be)
  • An open-label, phase I, dose-escalation and safety study of two intramuscular injections at dose of 2.9 log or 4 log CCID50 of the recombinant HIV I clade B measles vaccine vector in healthy adults. (biosafety.be)
  • Retroviral proteins, often glycosylated, coded by the envelope (env) gene. (lookformedical.com)
  • Proteins coded by the retroviral gag gene. (lookformedical.com)
  • Fully elucidating the early steps of retrovirus replication is therefore crucial not only for identifying new antiretroviral drugs, but also for improving the design of retroviral vectors for gene therapy. (biomedcentral.com)
  • A, B, C, and T) that are distinguished genetically by se- quence differences in the env gene and functionally by receptor interactions required for cell entry ( 13 ). (cdc.gov)
  • The predicted protein product belongs to the alkaline ceramidase, PAQR receptor, Per1, SID-1, and TMEM8 (CREST) superfamily of transmembrane hydrolase proteins and shows sequence similarity to Post-GPI-Attachment to Protein 6 (PGAP6), a GPI-PLA2 that acts after transfer of GPI precursors to protein in mammalian cells. (bvsalud.org)
  • The env genes contain a cis-acting RNA target sequence for the rev protein (= GENE PRODUCTS, REV ), termed the rev-responsive element (RRE). (lookformedical.com)
  • External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. (lookformedical.com)
  • Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. (lookformedical.com)
  • Here, we identify a gene, Tb927.7.6110, that encodes a protein that is both necessary and sufficient for GPI-phospholipase A2 (GPI-PLA2) activity in the procyclic form of the parasite. (bvsalud.org)
  • We show the trypanosome Tb927.7.6110 GPI-PLA2 gene resides in a locus with two closely related genes Tb927.7.6150 and Tb927.7.6170, one of which (Tb927.7.6150) most likely encodes a catalytically inactive protein. (bvsalud.org)
  • The FeLV-Pco virus health, wildlife managers released 8 female Texas pumas was closely related to the domestic cat exogenous FeLV-A into southern Florida to increase genetic variation and ame- subgroup in lacking recombinant segments derived from liorate the physiologic effects of inbreeding. (cdc.gov)
  • The shRNA packaged by the lentivirus inhibits GAS1 gene expression in human hepatoma cell line HepaRG (HepaRG-shNC and HepaRG-shGAS1-2) and primary hepatocytes of mice with liver-specific overexpression of GAS1 were isolated and induced by APAP in vitro to further investigate the regulatory role of GAS1 in APAP-induced acute liver failure. (bvsalud.org)
  • Growth arrest-specific 1 (GAS1) is a growth arrest-specific gene, which is closely related to the inhibition of cell growth and promotion of apoptosis. (bvsalud.org)
  • The aim of this study is to define www.selleckchem.com/products/isrib-trans-isomer.html the rheumatic manifestations of euthyroid patients with chronic lymphocytic thyroiditis (CLT) but without a well-defined connective tissue disease. (mdmpathway.com)
  • The FeLV-Pco virus health, wildlife managers released 8 female Texas pumas was closely related to the domestic cat exogenous FeLV-A into southern Florida to increase genetic variation and ame- subgroup in lacking recombinant segments derived from liorate the physiologic effects of inbreeding. (cdc.gov)
  • FeLV envelope ( env ) and the long (LTR4) was designed by using panther FeLV (FeLV-Pco) terminal repeat (LTR) sequences have been suggested as envelope sequence additionally. (cdc.gov)
  • The FeLV-Pco virus was closely related to the domestic cat exogenous FeLV-A subgroup in lacking recombinant segments derived from endogenous FeLV. (nih.gov)
  • In this study, we examined the effect of a recombinant envelope protein-based anti-KoRV vaccine in two groups of South Australian koalas: KoRV infected or KoRV free. (nature.com)
  • Recently, new genotypes, subtypes and recombinant SRLV viruses have been described widening significantly their genetic and antigenic heterogeneity, likely conferring them a wider spectrum of cell and host tropism. (biomedcentral.com)
  • The constitutive activation of the sonic hedgehog signaling pathway by acquired mutations within the PTCH and SMO genes seems to characterize the early basal cell carcinoma developmental determinant. (magainin.com)
  • For squamous cell carcinoma improvement, mutations within the p53 gene, particularly UV-induced mutations, have been recognized as early occasions. (magainin.com)