• agonist
  • Full agonists such as progesterone, which display agonist properties in all tissues, strongly shift the conformational equilibrium in the agonist direction. (wikipedia.org)
  • In addition, it is a weak agonist of the pregnane X receptor (PXR) (EC50 >10,000 µM)), with approximately six-fold lower potency relative to its 5β-isomer, 5β-dihydroprogesterone. (wikipedia.org)
  • functionally
  • Since the 1990s it has been evident that the two major receptor isomers, A and B, are functionally distinct within the female reproductive system. (wikipedia.org)