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  • AChRs
  • Localization of AChRs and ChE at sites of nerve-muscle contact occurred when the culture medium contained 1.2 micron tetrodotoxin (TTX), 1.2 micron TTX, 10 mM magnesium, and no calcium salts, 1.2 micron TTX and 2 mM manganese, or 106 mM potassium methyl sulfate instead of sodium chloride. (jneurosci.org)
  • fibers
  • This study aimed to investigate the frequency of nerve fibers that express 5-HT3A-receptors alone and in combination with NaV1.8 sodium-channels in human muscles and to compare it between healthy pain-free men and women, the pain-free masseter and tibialis anterior muscles, and patients with myofascial temporomandibular disorders (TMD) and pain-free controls. (uib.no)
  • Results: A similar percentage of nerve fibers in the healthy masseter (85.2%) and tibialis (88.7%) muscles expressed 5-HT3A-receptors. (uib.no)
  • 001). In the patients, significantly more fibers per section were found with an average of 3.8 ± 3 fibers per section in the masseter muscle compared to 2.7 ± 0.2 in the healthy controls (P = .024). (uib.no)
  • Conclusions: This study showed that the 5-HT3A-receptor is highly expressed in human masseter and tibialis muscles and that there are more nerve fibers that express 5-HT3A-receptors in the masseter of women with myofascial TMD compared to healthy women. (uib.no)
  • The vestibular nerve fibers arise from neurons of Scarpa's ganglion and project peripherally to vestibular hair cells and centrally to the VESTIBULAR NUCLEI of the BRAIN STEM. (bioportfolio.com)
  • synaptic
  • Here, we review and bring together the previously published data to emphasize the relevance of these receptors for developmental axonal competition, synaptic loss and mature NMJ functional modulation. (frontiersin.org)
  • sodium
  • Also, tetrodotoxin resistant voltage gated sodium-channels (NaV) are involved in peripheral sensitization and found in trigeminal ganglion neurons innervating the rat masseter muscle. (uib.no)
  • The mechanism of this block is instructive - ongoing stimulation of the receptors causes decreased electrical excitability due to inactivation of voltage-sensitive sodium channels. (anaesthetist.com)
  • neuronal
  • 6 To date, 17 nicotinic subunits have been cloned in vertebrates: the muscle α 1 , β 1 , δ, γ, and ϵ subunits and the neuronal α 2-10 and β 2-4 subunits. (asahq.org)
  • thus
  • This autoimmune reaction is excarcerbated by activity, thus muscles controlling eyes, mouth, neck etc. are the first to be affected because you use them all the time. (metafilter.com)
  • Thus, the integrated interpretation of the complementary function of all these receptors is needed. (frontiersin.org)
  • A modification of the Russian Cosmonaut Penguin suit is to move body parts against a resistance, thus improving muscle strength. (mychildwithoutlimits.org)
  • injection
  • Curare immobilises muscles minutes after injection. (ehow.co.uk)
  • Injection of the chemical edrophonium (Tensilon) may result in a sudden, although temporary, improvement in your muscle strength, an indication that you may have myasthenia gravis. (dreddyclinic.com)
  • affects
  • It most commonly affects certain muscles, including those of the face, eyes, arms and legs, and those involved in chewing, swallowing and breathing. (dreddyclinic.com)
  • specific
  • My dad has myasthenia gravis and this doesn't sound like MG to me, because MG isn't localized to specific nerves such that only the left eye would be affected. (metafilter.com)
  • These receptors can become stimulated by the presence of specific chemical substances. (cardiacmatters.co.uk)
  • Marijuana
  • Marijuana use can be used to treat and prevent the eye disease glaucoma, which increases pressure in the eyeball, damaging the optic nerve and causing loss of vision. (msn.com)
  • That same report said there's equally strong evidence marijuana can help with muscle spasms related to multiple sclerosis. (420magazine.com)
  • One of the most common reasons that states allow medical marijuana use is to treat and prevent the eye disease glaucoma, which increases pressure in the eyeball, damaging the optic nerve and causing loss of vision. (420magazine.com)
  • human
  • Background: Previous studies have shown that 5-HT3-antagonists reduce muscle pain, but there are no studies that have investigated the expression of 5-HT3-receptors in human muscles. (uib.no)
  • These learning tools will help you understand the most important facts about the vagus nerve and why it serves a vital role in the human body. (study.com)
  • potential
  • These findings indicate that 5-HT3-receptors might be up-regulated in myofascial TMD and could serve as potential biomarkers of chronic muscle pain. (uib.no)