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  • insulin
  • Quantitative determination of the lateral diffusion coefficients of the hormone-receptor complexes of insulin and epidermal growth factor on the plasma membrane of cultured fibroblasts. (springer.com)
  • sequence
  • Neural agrin, in addition to its unique ability to cluster AChRs through its B/z sequence insert, also exhibits laminin-dependent AChR clustering, the latter enhancing and stabilizing its activity. (unibas.ch)
  • Selective
  • Resistance to selective oestrogen receptor modulators (SERMs), chiefly tamoxifen, and to chemotherapy drugs often occurs, failing the goal of long-lasting remission and exposing patients to short and long-time side effects. (hindawi.com)
  • Growth
  • Rotational diffusion of epidermal growth factor complexed to its surface receptor the rapid microaggregation and endocytosis of occupied receptors. (springer.com)
  • Hillman GM, Schlessinger J. The lateral diffusion of epidermal growth factor complexed to its surface receptors does not account for the thermal sensitivity of patch formation and endocytosis. (springer.com)
  • High-affinity epidermal growth factor receptors on the surface of A-431 cells have restricted lateral diffusion. (springer.com)
  • role
  • 1-3 However, receptor immobilization also appears to play an important role in eliciting the stimulatory signal in other receptor systems. (springer.com)
  • The mobile receptor hypothesis revisited: a mechanistic role for hormone receptor lateral mobility in signal transduction. (springer.com)
  • Jans DA, Pavo I. A mechanistic role for polypeptide hormone receptor lateral mobility in signal transduction. (springer.com)