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  • 1995
  • 1995). GABA receptors are also located post-synaptically and when activated hyperpolarize the neuron thus decreasing the effectiveness of excitatory input (Malcangio and Bowery, 1996). (chiro.org)
  • aminobutyric acid
  • For example, by modifying the incubation conditions it has been possible to identify several pharmacologically and kinetically distinct binding sites for y-aminobutyric acid (GABA) in brain tissue. (springer.com)
  • Muscimol hydrobromide is a potent but toxic structural analog of g-aminobutyric acid (GABA), with a zwitterionic structure. (adooq.com)
  • aminobutyric acid (GABA), which primarily acts through GABAA receptors. (ideaconnection.com)
  • There are three receptors of the gamma-aminobutyric acid. (wikipedia.org)
  • Enrichment analyses revealed that GABA (gamma-aminobutyric acid) SNPs were over-represented among SNPs associated at po0.05 in both the discovery (Z = 3.64, p = 0.0003) and combined cohorts (Z = 2.07, p = 0.0388). (epfl.ch)
  • Presynaptic inhibition can occur through activation of spinal γ-aminobutyric acid (GABA) receptors on primary afferent fibers, which depolarize the terminal thus inhibiting neurotransmitter release from primary afferents and the consequent incoming afferent activity (see Eccles et al. (chiro.org)
  • Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. (abcam.com)
  • Protein
  • The GABAreceptor belongs to the class of G-Protein coupled receptors that inhibit adenylyl cyclase, therefore leading to decreased cyclic adenosine monophosphate (cAMP). (wikipedia.org)
  • It is concluded that GM might participate in the supramolecular organization of the GABA receptor complex, perhaps functioning as a modulator of this receptor protein. (jneurosci.org)
  • Belongs to the G-protein coupled receptor 3 family. (abcam.com)
  • GABA type A receptor associated protein like 1 is a protein that in humans is encoded by the GABARAPL1 gene. (wikipedia.org)
  • Protein kinase C (PKC) has been implicated in differentially modulating the response of the GABAA receptor to alcohol, with effects depending on the PKC isozyme. (wikipedia.org)