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  • CCL3
  • CCR1 is a chemokine receptor that responds to a large number of CC chemokines including CCL3 (MIP-1alpha), CCL5 (RANTES), CCL7 (MCP-3), CCL9 (MIP-1gamma), CCL15 (MIP1 delta), CCL23 (MIP-3), and with low affinity to CCL4 (MIP-1 beta) and CCL8 (MCP-2). (springer.com)
  • CCR1
  • Discovery and lead optimization of a novel series of CC chemokine receptor 1 (CCR1)-selective piperidine antagonists via parallel synthesis. (springer.com)
  • Gerard C, Frossard JL, Bhatia M, Saluja A, Gerard NP, Lu B, Steer M. Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury. (springer.com)
  • Khan IA, Murphy PM, Casciotti L, Schwartzman JD, Collins J, Gao JL, Yeaman GR. Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection. (springer.com)
  • angiogenesis
  • Chemokines exhibit a tremendous functional diversity and participate in a wide variety of processes that include inflammation, innate and adaptive immunity, immune cell differentiation, angiogenesis, tumorigenesis, development, neurobiology and viral pathogenesis. (springer.com)
  • Chemokines and Angiogenesis*Michael P. Keane, M.D., John A. Belperio, M.D., and Robert M.Strieter, M.D.University of California, Los Angeles and University of Virginia16. (indigo.ca)
  • Chemokine receptors play a role in leukocyte recruitment, activation, and maintaining effector functions and regulate adaptive immune response and angiogenesis. (hindawi.com)
  • novel
  • Chemokine Receptors targets the pharmaceutical industry, provides an authoritative perspective on the future direction of this field, and insights into areas of active development of novel therapeutics. (springer.com)
  • Neuroprotection in Ischemia-Reperfusion Injury: An Antiinflammatory Approach Using a Novel Broad-Spectrum Chemokine Inhibitor," Journal of Cerebral Blood Flow and Metabolism, vol. 21, 683-689, 2001. (patentgenius.com)
  • Antibodies
  • Committed to providing high quality research reagents in the formats and quantities researchers need, R&D Systems has introduced a 25-test size of our fluorochrome-conjugated chemokine receptor antibodies. (rndsystems.com)
  • In addition to this new size, our industry-leading chemokine receptor antibodies are also available in an economical 100-test size. (rndsystems.com)
  • integrins
  • This process is likely to be analogous to the homing of mature leukocytes, which involves selectin-mediated weak adhesion to vasculature endothelium, followed by chemokine signaling, strong adhesion through integrins, and transmigration ( 19 , 20 , 21 ). (jimmunol.org)