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  • inhibitors
  • Mercurials (sulfhydryl inhibitors) and haloalkylamine alpha adrenergic blocking agents (Dibenamine and phenoxybenzamine) exhibit identical action on melanophores of the lizard Anolis carolinensis . (aspetjournals.org)
  • neurotransmitter
  • The alpha adrenergic receptor system, which responds to the neurotransmitter adrenaline, is an important signaling mechanism in the body and is believed to be involved in such diverse therapeutic indications as cardiovascular disease, benign prostatic hyperplasia (BPH), pain and glaucoma. (thefreedictionary.com)
  • rauwolscine
  • Association, dissociation, and saturation studies revealed one site interactions (k -1/k+1 = 1.2 nM, KD = 2.5 nM, Bmax = 160 fmol/mg protein) and competition studies indicated that [3H]rauwolscine labeled the alpha 2-receptor. (nih.gov)
  • 3H] Rauwolscine bound in a saturable manner to a single class of receptors, with an equilibrium dissociation constant (KD) of 1.4 nM and a density (Bmax) of 71 fmol/mg of protein, in crude synaptic membrane preparations from bovine pineal gland. (aspetjournals.org)
  • metabolism
  • These regional and strain differences in the metabolism of alpha-methyldopa suggest that the production of methylnorepinephrine in brain stem nuclei is most correlated with the hypotensive action of methyldopa. (ahajournals.org)
  • human
  • Autonomic Receptor-mediated Regulation of Production and Release of Nitric Oxide in Normal and Malignant Human Urothelial Cells. (abcam.com)
  • Expression Profiles of Neuropeptides, Neurotransmitters, and Their Receptors in Human Keratocytes In Vitro and In Situ. (abcam.com)
  • insulin
  • These results suggest that insulin, by modulating α 2 adrenergic receptor levels, is able to regulate the amount of NE present in the synaptic cleft. (springer.com)
  • D. W. Clarke, F. T. Boyd, Jr., M. S. Kappy, and M. K. Raizada, Insulin binds to specific receptors and stimulates 2-deoxy-D-glucose uptake in cultured glial cells from rat brain, J. Biol. (springer.com)
  • Richards E.M., Raizada M.K., Sumners C. (1987) Insulin Downregulates Alpha-2 Adrenergic Receptors in Cultured Glial Cells. (springer.com)
  • In: Raizada M.K., Phillips M.I., LeRoith D. (eds) Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System. (springer.com)