Receptor tyrosine kinase inhibitors. Medical search. Frequent questions

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Anatomy11

Cell Line, Tumor Cells, Cultured Cell Line Tumor Cells, Cultured 3T3 Cells COS Cells Cell Membrane NIH 3T3 Cells PC12 Cells Fibroblasts Cell Line, Transformed

Organisms7

Mice, Nude Rats, Sprague-Dawley Mice, SCID Mice, Inbred BALB C Mice, Knockout Mice, Inbred C57BL Cricetinae

Diseases17

Lung Neoplasms Carcinoma, Non-Small-Cell Lung Neoplasms Leukemia, Myelogenous, Chronic, BCR-ABL Positive Neovascularization, Pathologic Carcinoma, Renal Cell Kidney Neoplasms Adenocarcinoma Exanthema Breast Neoplasms Glioblastoma Cell Transformation, Neoplastic Neoplasm Metastasis Brain Neoplasms Gastrointestinal Stromal Tumors Head and Neck Neoplasms Disease Progression

Chemicals and Drugs159

Protein Kinase Inhibitors Receptor Protein-Tyrosine Kinases Quinazolines Protein-Tyrosine Kinases Tyrosine Receptor, Epidermal Growth Factor Pyrimidines Pyrroles Antineoplastic Agents Indoles Benzamides Enzyme Inhibitors Tyrphostins Piperazines Receptors, Vascular Endothelial Growth Factor Genistein Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins src-Family Kinases Proto-Oncogene Proteins c-met Phenylurea Compounds Phthalazines Angiogenesis Inhibitors Phosphotyrosine Receptors, Platelet-Derived Growth Factor Proto-Oncogene Proteins c-kit Indazoles Pyridines Protein-Serine-Threonine Kinases Epidermal Growth Factor Protein Tyrosine Phosphatases Receptor, erbB-2 Mitogen-Activated Protein Kinases Receptor, Platelet-Derived Growth Factor beta Protein Kinases Vascular Endothelial Growth Factor Receptor-2 Receptor Tyrosine Kinase-like Orphan Receptors fms-Like Tyrosine Kinase 3 Quinazolinones Calcium-Calmodulin-Dependent Protein Kinases Proto-Oncogene Proteins c-akt Benzenesulfonates Lactams, Macrocyclic Receptors, Eph Family Receptor, EphA2 Benzoquinones Protein Kinase C Quinones Fusion Proteins, bcr-abl Mitogen-Activated Protein Kinase 1 Phosphoproteins Quinolines Niacinamide Proto-Oncogene Proteins c-abl Proto-Oncogene Proteins c-ret Receptor, EphB2 Mitogen-Activated Protein Kinase 3 Isoflavones Vascular Endothelial Growth Factor A Adaptor Proteins, Signal Transducing Intracellular Signaling Peptides and Proteins Receptor, EphA4 Thiazoles Proto-Oncogene Proteins pp60(c-src)Piperidines Receptor, Insulin Receptor, EphB4 Vanadates Receptor, erbB-3 Recombinant Fusion Proteins RNA, Messenger Receptor, trkA Receptors, Growth Factor Antibodies, Monoclonal Hepatocyte Growth Factor Ephrin-A1 Staurosporine p38 Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase Kinases Nitriles Receptor, TIE-2 Recombinant Proteins Extracellular Signal-Regulated MAP Kinases HLA-DR1 Antigen Vascular Endothelial Growth Factor Receptor-1 Proteins Cyclin-Dependent Kinase Inhibitor p27 Ligands Cyclic AMP-Dependent Protein Kinases Ephrins Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Receptor, IGF Type 1 Phospholipase C gamma Ephrin-B1 GRB2 Adaptor Protein Ephrin-B2 Receptor, Platelet-Derived Growth Factor alpha Janus Kinase 2 Focal Adhesion Protein-Tyrosine Kinases Membrane Proteins Receptor, EphA1 Morpholines Type C Phospholipases Oncogene Proteins JNK Mitogen-Activated Protein Kinases Isoenzymes ras Proteins Receptors, TIE Phosphotransferases (Alcohol Group Acceptor)Receptor, TIE-1 Proto-Oncogene Proteins c-cbl Tyrosine 3-Monooxygenase Receptor, trkB Focal Adhesion Kinase 1 Platelet-Derived Growth Factor Receptors, Cell Surface Cyclin-Dependent Kinases Protein Tyrosine Phosphatase, Non-Receptor Type 11 Oncogene Proteins v-erbB Androstadienes Shc Signaling Adaptor Proteins RNA, Small Interfering Chromones Focal Adhesion Kinase 2 Flavonoids Receptors, Mitogen Organic Chemicals Ephrin-A2 Calcium Indole Alkaloids MAP Kinase Kinase 1 Receptors, Fibroblast Growth Factor Drosophila Proteins Receptor, EphB6 Receptor, EphA3 DNA Primers Carbazoles DNA-Binding Proteins Cyclin-Dependent Kinase Inhibitor p21 Stem Cell Factor Neuregulins Neuregulin-1 p21-Activated Kinases Pyrazoles Receptor, EphB3 Tumor Markers, Biological Sirolimus Nerve Growth Factors Ribosomal Protein S6 Kinases DNA, Complementary Intercellular Signaling Peptides and Proteins Imidazoles Carrier Proteins Receptor, Macrophage Colony-Stimulating Factor Cinnamates Tetradecanoylphorbol Acetate Glial Cell Line-Derived Neurotrophic Factor Receptors MAP Kinase Kinase Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Xenograft Model Antitumor Assays Blotting, Western Transfection Administration, Oral Immunohistochemistry Drug Screening Assays, Antitumor Treatment Outcome Inhibitory Concentration 50 Precipitin Tests Immunoblotting Neoplasm Transplantation Models, Biological Maximum Tolerated Dose Clinical Trials as Topic Molecular Targeted Therapy Reverse Transcriptase Polymerase Chain Reaction Mutagenesis, Site-Directed Cloning, Molecular Immunoprecipitation Models, Molecular

Phenomena and Processes38

Phosphorylation Signal Transduction Drug Resistance, Neoplasm Enzyme Activation Mutation Dose-Response Relationship, Drug Cell Proliferation MAP Kinase Signaling System Cell Division Apoptosis Amino Acid Sequence Transfection Protein Binding Cell Movement Cell Survival Protein Structure, Tertiary src Homology Domains Drug Synergism Time Factors Base Sequence Inhibitory Concentration 50 Gene Expression Regulation, Neoplastic Kinetics Binding Sites Down-Regulation Sequence Homology, Amino Acid Maximum Tolerated Dose Gene Expression Cell Cycle Cell Differentiation Substrate Specificity Genes, erbB Cell Adhesion Gene Expression Regulation Up-Regulation Genes, erbB-1 Protein Processing, Post-Translational Structure-Activity Relationship

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care2

Treatment Outcome Clinical Trials as Topic

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Protein Kinase Inhibitors Receptor Protein-Tyrosine Kinases Quinazolines Protein-Tyrosine Kinases Tyrosine Receptor, Epidermal Growth Factor Phosphorylation Pyrimidines Signal Transduction Pyrroles Antineoplastic Agents Indoles Benzamides Enzyme Inhibitors Tyrphostins Piperazines Cell Line, Tumor Receptors, Vascular Endothelial Growth Factor Genistein Lung Neoplasms Phosphatidylinositol 3-Kinases Drug Resistance, Neoplasm Proto-Oncogene Proteins Enzyme Activation src-Family Kinases Proto-Oncogene Proteins c-met Phenylurea Compounds Carcinoma, Non-Small-Cell Lung Phthalazines Mutation Angiogenesis Inhibitors Phosphotyrosine Dose-Response Relationship, Drug Receptors, Platelet-Derived Growth Factor Cell Proliferation Proto-Oncogene Proteins c-kit Indazoles Pyridines MAP Kinase Signaling System Xenograft Model Antitumor Assays Cells, Cultured Protein-Serine-Threonine Kinases Epidermal Growth Factor Mice, Nude Protein Tyrosine Phosphatases Cell Line Receptor, erbB-2 Tumor Cells, Cultured Molecular Sequence Data Cell Division Mitogen-Activated Protein Kinases Receptor, Platelet-Derived Growth Factor beta Apoptosis Blotting, Western Protein Kinases Vascular Endothelial Growth Factor Receptor-2 Receptor Tyrosine Kinase-like Orphan Receptors fms-Like Tyrosine Kinase 3 Amino Acid Sequence Quinazolinones Calcium-Calmodulin-Dependent Protein Kinases Proto-Oncogene Proteins c-akt Neoplasms Benzenesulfonates Lactams, Macrocyclic Receptors, Eph Family Receptor, EphA2 Transfection Leukemia, Myelogenous, Chronic, BCR-ABL Positive Benzoquinones Administration, Oral Protein Kinase C Protein Binding Quinones Fusion Proteins, bcr-abl Mitogen-Activated Protein Kinase 1 Neovascularization, Pathologic Phosphoproteins Quinolines Cell Movement Niacinamide 3T3 Cells Proto-Oncogene Proteins c-abl Proto-Oncogene Proteins c-ret Receptor, EphB2 Cell Survival Mitogen-Activated Protein Kinase 3 Isoflavones Vascular Endothelial Growth Factor A Protein Structure, Tertiary Adaptor Proteins, Signal Transducing src Homology Domains Drug Synergism Immunohistochemistry Time Factors Intracellular Signaling Peptides and Proteins Receptor, EphA4 Thiazoles Proto-Oncogene Proteins pp60(c-src)Piperidines

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