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  • Proteins
  • The cDNA library for the screen was prepared from rough endoplasmic reticulum-bound mRNA and is therefore enriched in clones encoding membrane and secreted proteins. (pnas.org)
  • Controlling the Editor: The Many Roles of RNA-Binding Proteins in Regulating A-to-I RNA Editing. (iu.edu)
  • In contrast, the exchange of non-conserved residues in the LBD that convert antagonist selectivity of GluK1-3 (GluK1-T503A, GluK2-A487T, GluK3-T489A, GluK1-N705S/S706N, GluK2-S689N/N690S, GluK3-N691S) did not alter the biosynthesis and trafficking of subunit proteins. (springer.com)
  • Thus, our data demonstrate that the expression of AMPARs divides inhibitory interneurons in macaque V1 into two categories that are compatible with existing classification methods based on calcium-binding proteins and firing behavior. (jneurosci.org)
  • One important classification scheme relies on the differential expression pattern of calcium-binding proteins (CBPs), such as parvalbumin (PV), calbindin (CB), and calretinin (CR). (jneurosci.org)
  • All opioid receptors are linked through G-proteins to inhibition of adenylate cyclase. (brainscape.com)
  • 1997
  • Bennett PA, Thomas GB, Howard AD, Feighner SD, van der Ploeg LH, Smith RG, Robinson IC (1997) Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat. (springer.com)
  • GluA2
  • D, the symmetry mismatch between the TMDs and the extracellular domains (ATDs and LBDs) as well as the subunit crossover (or domain swapping) from the LBD to the ATD give rise to two distinct types of subunits in the homotetrameric GluA2 receptor with two distinct conformations. (nih.gov)
  • We found that PV-IR cells, which have previously been identified as fast spiking, show high expression of the GluA2 and GluA3 subunits. (jneurosci.org)
  • EMDB-8823: Activated GluA2 complex bound to glutamate, cyclothiazide, and ST. (pdbj.org)
  • isoforms
  • Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. (abnova.com)