Receptors, N-Methyl-D-AspartateRats, Sprague-DawleySignal TransductionDose-Response Relationship, DrugCells, CulturedNeuronsMice, KnockoutMice, Inbred C57BLCell LineCalciumPhosphorylationApoptosisRNA, MessengerMolecular Sequence DataEnzyme ActivationGene Expression RegulationUp-RegulationRNA, Small InterferingCell Line, TumorBlotting, WesternTime FactorsDNA-Binding ProteinsEnzyme InhibitorsTransfectionProtein BindingTranscription FactorsTumor Suppressor Protein p53Down-RegulationMice, Inbred BALB CMice, TransgenicKineticsCell ProliferationTranscription, GeneticPromoter Regions, GeneticCarrier ProteinsBase SequenceAmino Acid SequenceCell MovementReverse Transcriptase Polymerase Chain ReactionMutationCell DifferentiationMembrane ProteinsTrans-ActivatorsCyclooxygenase 2Models, BiologicalRNA InterferenceSTAT6 Transcription FactorProtein-Serine-Threonine KinasesMacrophagesLipopolysaccharidesCell SurvivalFlow CytometrySTAT3 Transcription FactorRecombinant ProteinsToll-Like Receptor 4Myeloid Differentiation Factor 88Protein TransportTumor Necrosis Factor-alphaCell AdhesionTumor Cells, CulturedKeratin-17Calcium SignalingToll-Like Receptor 2DinoprostoneMembrane GlycoproteinsEpithelial CellsMAP Kinase Signaling SystemTranscriptional ActivationFibroblastsGene ExpressionHEK293 CellsNuclear ProteinsNF-kappa BNeutrophilsBinding SitesHeLa CellsSodiumNitric OxideHydrogen-Ion ConcentrationCell MembraneDisease Models, Animalp38 Mitogen-Activated Protein KinasesEndothelium, VascularCytokinesProtein Kinase CBiological TransportMitogen-Activated Protein KinasesImmunoprecipitationRecombinant Fusion ProteinsCyclic AMPAntigens, CD18Rats, WistarProto-Oncogene Proteins c-aktImmunoblottingCell DivisionCell Cycle ProteinsInterleukin-4Endothelial CellsAntigens, CD14Phosphatidylinositol 3-Kinases